检索结果-南通市图书馆

Relevance of plasma lipoproteins and small metabolites in assessment of nutritional status among patients with severe injuries

引用

Journal of Intensive Medicine 2024年第4期4卷 496-507页

作者： Esmee A.H.Verheul Suzan Dijkink Pieta Krijnen Aswin verhoeven Martin Giera Roula Tsonaka Jochem M.Hoogendoorn Sesmu M.Arbous Ron Peters Inger B.Schipper Department of Trauma Surgery Leiden University Medical CenterLeidenThe Netherlands Acute Care Network West Netherlands LeidenThe Netherlands Center for Proteomics and Metabolomics Leiden University Medical CenterLeidenThe Netherlands Department of Biomedical Data Sciences Leiden University Medical CenterLeidenThe Netherlands Department of General Surgery Haaglanden Medical CenterThe HagueThe Netherlands Department of Intensive Care Leiden University Medical CenterLeidenThe Netherlands Department of Intensive Care Haaglanden Medical CenterThe HagueThe Netherlands

Background:This study aimed to identify plasma lipoproteins and small metabolites associated with high risk of malnutrition during intensive care unit(ICU)stay in patients with severe ***:This observational prospective exploratory study was conducted at two level-1 trauma centers in the *** patients(aged≥18 years)who were admitted to the ICU for more than 48 h between July 2018 and April 2022 owing to severe injuries(polytrauma,as defined by Injury Severity Scores of≥16)caused by blunt trauma were eligible for *** least squares discriminant analysis was used to analyze the relationship of 112 lipoprotein-related components and 23 small metabolites with the risk of malnutrition(mod-ified Nutrition Risk in Critically Ill score).Malnutrition was diagnosed based on Subjective Global Assessment *** relationship of lipoprotein properties and small metabolite concentrations with malnutrition(during ICU admission)was evaluated using mixed effects logistic ***:Overall,51 patients were ***(very)low-density lipoprotein([V]LDL)(free)cholesterol and phospholipid levels,low particle number,and higher levels of LDL triglycerides were associated with a higher risk of malnutrition(variable importance in projection[VIP]value>1.5).Low levels of most(V)LDL and intermediate-density lipoprotein subfractions and high levels of high-density lipoprotein Apo-A1 were associated with the diagnosis of malnutrition(VIP value>1.5).Increased levels of dimethyl sulfone,trimethylamine N-oxide,creatinine,N,N-dimethylglycine,and pyruvic acid and decreased levels of creatine,methionine,and acetoacetic acid were also indicative of malnutrition(VIP value>1.5).Overall,14 lipoproteins and 1 small metabolite were significantly associated with a high risk of malnutrition during ICU admission(P<0.05);however,the association did not persist after correcting the false discovery rate(P=0.35 for all).Conclusion:Increased triglyceride in sev

关键词： Trauma Severely injured Metabolites Lipoproteins Malnutrition Nutritional status

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Access to Higher Education of 25 Ethnic Minorities in Yunnan Province,South Western China

引用

Frontiers of Education in China 2010年第2期5卷 290-308页

作者： Jianxin Zhang Jef C.verhoeven Research Institute of Higher Education Yunnan UniversityKunming 650091China Centre for Sociological Research University of LeuvenLeuven 3000Belgium

The level of development of higher education(HE)is an important indicator to measure the development of the social economy and the civilization of a region or *** this article,we compare the distribution of the freshmen of ethnic minorities(EMs)with the distribution of EMs over the population,based on a sample of 1464 freshmen from 25 EMs of Yunnan Province in People's Republic of China(PRC).Although this analysis shows that access to HE is equal for some categories of EM students,it still shows that access to HE is harder for these minorities in comparison with freshmen from Han(major ethnic group comprising of 92%of the Chinese population)families.

关键词： ethnic minority undergraduate access to higher education education equality

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

HAMILTONIANS WITH TWO DEGREES OF FREEDOM ADMITTING A SINGLEVALUED GENERAL SOLUTION

引用

Analysis in Theory and Applications 2005年第2期21卷 188-200页

作者： R.Conte M.Musette C.verhoeven CEA-Saclay Vrije UniversiteitVrije Universiteit FranceBelgiumBelgium

Following the basic principles stated by Painlevé, we first revisit the process of selecting the admissible time-independent Hamiltonians H = （p1^2 ＋ p2^2）/2 ＋ V（q1, q2） whose some integer power qj^nj （t） of the general solution is a singlevalued function of the complez time t. In addition to the well known rational potentials V of Hénon-Heiles, this selects possible cases with a trigonometric dependence of V on qj. Then, by establishing the relevant confluences, we restrict the question of the explicit integration of the seven （three “cubic” plus four “quartic”） rational Hénon-Heiles cases to the quartic cases. Finally, we perform the explicit integration of the quartic cases, thus proving that the seven rational cases have a meromorphic general solution explicitly given by a genus two hyperelliptic function.

关键词： two degree of freedom Hamiltonians Painlevé test Painlevé property Hdnon-Heiles Hamiltonian hyperelliptic

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Clinical characteristics and outcomes of patients with hepatic angiomyolipoma:A literature review

引用

World Journal of Gastroenterology 2021年第19期27卷 2299-2311页

作者： Paul Calame Gaelle Tyrode Delphine Weil verhoeven Sophie Felix Anne Julia Klompenhouwer Vincent Di Martino Eric Delabrousse Thierry Thevenot Department of Radiology Jean Minjoz University HospitalBesançon 25030France Department of Hepatology Jean Minjoz University HospitalBesançon 25030France Department of Pathology Jean Minjoz University HospitalBesançon 25000France Department of Surgery Erasmus University Medical CenterRotterdam PO Box 2040The Netherlands

First reported in 1976,hepatic angiomyolipoma(HAML)is a rare mesenchymal liver tumor occurring mostly in middle-aged *** of the liver mass is often incidental on abdominal imaging due to the frequent absence of specific *** 10%of HAMLs are associated with tuberous sclerosis *** contains variable proportions of blood vessels,smooth muscle cells and adipose tissue,which renders radiological diagnosis *** express positivity for HMB-45 and actin,thus these tumors are integrated into the group of perivascular epithelioid cell ***,a HAML appears on magnetic resonance imaging(or computed tomography scan)as a hypervascular solid tumor with fatty areas and with washout,and can easily be misdiagnosed as other liver tumors,particularly hepatocellular *** therapeutic strategy is not clearly defined,but surgical resection is indicated for symptomatic patients,for tumors showing an aggressive pattern(i.e.,changes in size on imaging or high proliferation activity and atypical epithelioid pattern on liver biopsy),for large(>5 cm)biopsy-proven HAML,and if doubts remain on imaging or *** management may be justified in other conditions,since most cases follow a benign clinical *** summary,the correct diagnosis of HAML is challenging on imaging and relies mainly on pathological findings.

关键词： Angiomyolipoma Liver Tuberous sclerosis complex Imaging Pathology Potentially malignant

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

从欧洲的三个国家看——大学与政府关系的变化

引用

清华大学教育研究 2003年第5期24卷 1-8页

作者： Jef C.verhoeven 郭歆比利时鲁汶大学

近十年来,西欧的政策呈现出放松管制、组织自治和标榜对个体公民更加关切的特点。这种政策态度在欧洲的高等教育界成了主流意识形态。本文想要展示的是,是否一些欧盟政府在管理高等教育方面采取了“后退”的作法,是否将制定高等教育政... 详细信息

近十年来,西欧的政策呈现出放松管制、组织自治和标榜对个体公民更加关切的特点。这种政策态度在欧洲的高等教育界成了主流意识形态。本文想要展示的是,是否一些欧盟政府在管理高等教育方面采取了“后退”的作法,是否将制定高等教育政策作为自己的目标。欧洲政府的高等教育政策是否真的呈现分权化的特点?本文将对三个欧洲国家的高教政策进行讨论,它们分别具有不同的政策传统:法国(非常集权的政策传统)、英国(分权的政策传统)、比利时(集权的政策传统)。本文的研究结论是:到目前为止,法国的教育政策虽然还呈现集权的特点,但并不意味着高校完全没有选择它们发展方向的空间。而英国大学虽然仍独立于政府,但不止一次地被政府直接或非直接地推向某一特定方向。1989年以前,比利时(佛兰德区)保留着明最的集权的特点。而现在,高等教育政策已经不仅仅是政府的事情了,它比以往任何时候更成了私人机构的职责。

关键词：欧洲法国英国比利时大学政府教育政策集权制分权制教育管理

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Generic Service Architecture for Secure Ubiquitous Computing Systems

引用

International Journal of Communications, Network and System Sciences 2012年第1期5卷 50-65页

作者： Shudong Chen Johan Lukkien Richard verhoeven Department of Mathematics and Computer Science Eindhoven University of Technology

The development of ubiquitous computing systems benefits tremendously from the service-oriented computing concept in seamless interoperation of heterogeneous devices. However, architectures, services interfaces and network implementation of the existing service-oriented systems differ case by case. Furthermore, many systems lack the capability of being applied to resource constrained devices, for example, sensors. Therefore, we propose a standardized approach to present a service to the network and to access a networked service, which can be adopted by arbitrary types of devices. In this approach, services are specified and exposed through a set of standardized interfaces. Moreover, a virtual community concept is introduced to determine a secure boundary within which services can be freely discovered, accessed and composed into applications;a hierarchical management scheme is presented which enables the third party management of services and their underlying resources. In this way, application control logic goes into the network and environment context is dealt with intelligently by the system. A prototype system is developed to validate our ideas. Results show the feasibility of this open distributed system software architecture.

关键词： Generic Programming Service Orientation Ubiquitous Computing Virtual Community Context-Aware Resource Management

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Alfapump®implantable device in management of refractory ascites:An update

引用

World Journal of Hepatology 2022年第7期14卷 1344-1356页

作者： Delphine Weil-verhoeven Vincent Di Martino Guido Stirnimann Jean Paul Cervoni Eric Nguyen-Khac Thierry Thévenot Service d’Hépatologie Et Soins Intensifs Digestifs CHRU Jean MinjozBesançon 25030France EA 4266 EPILAB Universitéde Bourgogne Franche-ComtéBesançon 25030France Department of Visceral Surgery and Medicine Inselspital University Hospital and University of BernBern 3010Switzerland Service d’Hépato-Gastroentérologie CHU Amiens-PicardieAmiens 80080France

Refractory ascites(RA)is a frequent and life-threatening complication of *** selected patients with RA,transjugular intrahepatic portosystemic shunt(TIPS)placement and liver transplantation(LT)are currently considered the best therapeutic alternatives to repeated large volume *** patients with a contraindication to TIPS or LT,the alfapump®system(Sequana Medical,Ghent,Belgium)has been developed to reduce the need for iterative paracentesis,and consequently to improve the quality of life and nutritional *** report here recent data on technical progress made since the first implantation,the efficacy and tolerance of the device,the position of the pump in the therapeutic arsenal for refractory ascites,and the grey areas that remain to be clarified regarding the optimal selection of patients who are potential candidates for this treatment.

关键词： Alfapump Refractory ascites Automated low flow ascites pump Cirrhosis Liver

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Using modular 3D digital earth applications based on point clouds for the study of complex sites

引用

International Journal of Digital Earth 2016年第12期9卷 1135-1152页

作者： Oscar Martinez-Rubi Maurice de Kleijn Stefan verhoeven Niels Drost Jisk Attema Maarten van Meersbergen Rob van Nieuwpoort Rens de Hond Eduardo Dias Pjotr Svetachov Netherlands eScience Center AmsterdamThe Netherlands Spatial Information laboratory(SPINlab) VU University AmsterdamAmsterdamThe Netherlands Faculty of Arts Institute for HistoricalLiterary and Cultural studies(HLCS)Radboud UniversityNijmegenThe Netherlands Geodan b.v. AmsterdamThe Netherlands Donald Smits Center for Information Technology University of GroningenGroningenThe Netherlands

This article discusses the use of 3D technologies in digital earth applications(DEAs)to study complex *** are large areas containing objects with heterogeneous shapes and semantic *** study proposes that DEAs should be modular,have multi-tier architectures,and be developed as Free and Open Source Software if *** DEAs requiring high reliability in the 3D measurements,point clouds are proposed as basis for the 3D Digital digital earth *** the development of DEAs,we propose to follow a workflow with four components:data acquisition and processing,data management,data analysis and data *** every component,technological challenges of using 3D technologies are identified and solutions applied for a case study are *** case study is a modular 3D DEA developed for the archaeological project Mapping the Via *** 3D DEA allows archaeologists to virtually analyze a complex study area.

关键词： 3D digital earth application point clouds data management visualization

来源：

维普期刊数据库评论