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Antiurolithiatic activity of Aavarai Bhavanai Chooranam a Siddha polyherbal formulation on ethylene glycol-induced urolithiasis in Wister albino rats

引用

Drug Combination Therapy 2022年第4期4卷 25-29页

作者： Harishanbuselvan venkatesan Arthi Gurumurthy Rathinam Jayaraj Lakshmanakumar venkatachalam Resident Medical Officer National Institute of SiddhaChennai 600047Tamil NaduIndia Sai Siddha Clinic Salem 636354Tamil NaduIndia Govt upgraded Primary Health Centre EriayamangalamNamakkal 637210Tamil NaduIndia All India Institute of Medical Sciences(AIIMS) Raipur 492099ChattishgarhIndia

Background:Aavarai Bhavanai Chooranam(ABC)is a Siddha polyherbal formulation containing ten medicinal plants that have been used in the Siddha system of medicine,practiced in the Southern part of Tamil Nadu,India for the management of ***:The study is carried out to scientifically validate the traditional formulation and to study the mechanism of ***:In the present study,the antiurolithiatic activity of ABC was evaluated in Wister albino rats by using ethylene glycol through drinking *** I acted as the standard control group and was given unlimited access to conventional rat food and *** II-v was given ethylene glycol(0.75%)in water to induce renal calculi for 28 *** III got the typical anti-urolithiatic medication,Cystone(750 mg/kg),from the 15th day to the 28th day,whereas Group II functioned as the lithiatic control group and received the *** Bhavanai Chooranam(200 mg/kg)was administered to Group Iv from the 15th to the 28th day as a curative *** the first day to the 28th day,Group v received Aavarai Bhavanai Chooranam(200 mg/kg),which was administered as a preventative *** groups'urine samples were taken,and using accepted techniques,their calcium,magnesium,oxalate,inorganic phosphate,protein,and creatinine levels were *** treatment promotes diuresis which leads to flushing of the renal stones and maintains the alkaline condition in the urinary system which probably mediates the antilithiatic ***:ABC provides structural and functional protection to the kidneys by enhancing its physiological function against stone formation and validates its clinical use.

关键词： Aavarai Bhavanai Chooranam ethylene glycol kalladaippu Siddha drug urolithiasis

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