检索结果-南通市图书馆

Vibrational spectra of oxygen and nitrogen-bridged iron octaethylporphyrin dimers by an U(2) algebraic

Journal of Biophysical Chemistry 2011年第3期2卷 310-315页

作者： Srinivasa rao Karumuri J. Vijayasekhar Sreeram Venigalla venkata basaveswara rao mandava Uma Maheswara rao Velagapudi Department of Electronics & Instrumentations Lakireddy Bali Reddy College of Engineering Mylavaram India Department of Mathematics GITAM University Hyderabad India Department of Chemistry P. G. Centre P. B. Siddhartha College Vijayawada India Department of Chemistry Krishna University Machilipatnam India Department of Applied Mathematics Andhra University Vishakapatnam India

Using U (2) algebraic model Hamiltonian the resonance Raman spectra of Oxygen bridged iron porphyrin dimers (OEPFe)2O and (OEPFe)2N calculated for selected some vibrational modes. Using this model the Hamiltonian so c... 详细信息

关键词： Vibrational Spectra Lie Algebra Octatehylporphyrin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neuroprotection by Melatonin on Mercury Induced Toxicity in the Rat Brain

引用

Pharmacology & Pharmacy 2011年第4期2卷 375-385页

作者： mandava V. rao Anshita R. Purohit 不详

Free radicals are common outcome of normal aerobic cellular metabolism. In-built antioxidant system of body plays its decisive role in prevention of any loss due to free radicals. However, imbalanced defense mechanism of antioxidants and overproduction or incorporation of free radicals from environment to living systems leads to serious damage. It also attacks nervous system resulting in neural-degeneration. In order to evaluate the neurotoxic effect on the brain parts of mercury in our study, oxidative stress indices of enzymatic and non enzymatic components were measured in rats intoxicated with mercury (2 mg and 4 mg/kg body weight) for 60 days to adult rats. Along with gravimetry, tissue burden was also recorded. Alterations in these indices were further supported by ultrastructural studies carried out in the brain as indicated by myelin disintegration, cell organelle alterations and neuronal loss by mercury poisoning. Treatment with the antioxidant melatonin (N-acetyl 5-methoxy tryptamine, 5 mg/kg) prevented mercury exerted toxicity due to its antioxidant property. The pathological changes were also ameliorated in the brain region comparatively to support biochemical profile of brain. Thus, melatonin produced neuroprotection against mercury poisoning in rats.

关键词： Mercuric Chloride Melatonin Neuroprotection Cerebral Hemisphere Cerebellum Medulla Oblongata Rats

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatoprotective evaluation of Anogeissus latifolia:In vitro and in vivo studies

引用

World Journal of Gastroenterology 2009年第38期15卷 4816-4822页

作者： Hulikere Ananth Pradeep Saleemullah Khan Karamkonda Ravikumar Mohammed Fazil Ahmed Meesala Srinivasa rao mandava Kiranmai Dachani Sudhershan Reddy Shaik Rasheed Ahamed Mohammed Ibrahim Department of Pharmacology and Biotechnology Nizam Institute of Pharmacy JSS College of Pharmacy OotyTamilnaduIndia and Manipal College of Pharmaceutical Sciences Centre for Liver Research and Diagno-stics Deccan College of Medical Sciences and Allied Hospitals

AIM： To evaluate the hepatoprotective activity of a hydroalcoholic extract of the bark of Anogeissus latifolia; in vitro in primary rat hepatocyte monolayer culture and in vivo in the liver of Wistar rats intoxicated by carbon tetrachloride （CCl4）. METHODS： In the in vitro study, a primary hepatocyte monolayer culture was treated with CCh and extract of Anogeissus latifolia. Hepatoprotective activity was demonstrated in the CCh damaged primary monolayer culture. In the in vivo study, the hepatoprotective activity of a hydroalcoholic extract ofAnogeissus latifolia was analyzed in liver injured CCh-treated rats. Biochemical parameters including serum transaminases [aspartate aminotransferase （AST） and alanine aminotransferase （ALT）] and alkaline phosphatase （ALP） in serum wereanalyzed. The biochemical findings were supplemented with histopathological examination of rat liver sections. RESULTS： In vitro： primary hepatocyte monolayer cultures were treated with CCh and extract of Anogeissus latifolia. A protective activity could be demonstrated in the CCh damaged primary monolayer cultUre. In vivo： Hydroalcoholic extract of Anogeissus latifolia （300 mg/kg） was found to have protective activity in rats with CCh-induced liver damage as judged from serum marker enzyme activity. CONCLUSION： The above findings lead to the conclusion that the hydroalcoholic extract of Anogeissus latifol/a is hepatoprotective. Hence, we suggest that the inclusion of this plant in the management of liver disorders is justified.

关键词： Anogeissus latifolial Hepatoprotective Carbon tetrachloride

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：