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A transversal pilot study of oropharyngeal carriage of Kingella kingae in healthy children younger than 6 months

World Journal of Pediatrics 2017年第6期13卷 615-617页

作者： vasiliki spyropoulou Gabriel Br(a)ndle Albane Bertha Rosa Maggio Rebecca Anderson della Llana Abdessalam Cherkaoui Gesuele Renzi Jacques Schrenzel Sergio Manzano Dimitri Ceroni Child and Adolescent Department University Hospitals of GenevaGenevaSwitzerland Pediatric Sport Medicine and Obesity Care Program University Hospitals of GenevaGenevaSwitzerland Intensive Care Unit University Hospitals of GenevaGenevaSwitzerland Clinical Microbiology Laboratory Service of Infectious DiseasesUniversity Hospitals of GenevaGenevaSwitzerland Clinical Microbiology Laboratory Service of Infectious DiseasesUniversity Hospitals of GenevaGenevaSwitzerland Genomic Research Laboratory Service of Infectious DiseasesUniversity Hospitals of GenevaGenevaSwitzerland Pediatric Emergency Division University Hospitals of GenevaGenevaSwitzerland Pediatric Orthopedic Service University Hospitals of GenevaGenevaSwitzerland

Background:The aim of this pilot study was to investigate the extent of oropharyngeal Kingella kingae carriage during the first 6 months of ***:We conducted a monocentric transversal pilot study on healthy children younger than 6 months in order to define the oropharyngeal carriage *** were recruited between December 2013 and September 2015 among children without symptoms or signs of invasive ***:We demonstrated an oropharyngeal carriage rate of 0.67% in children younger than 6 *** to the really low carriage rate,it was not possible to draw statistically significant conclusion about any other characteristic of our ***:The present study suggests that the oropharyngeal carriage of Kingella kingae among a Swiss population of healthy infants younger than 6 months is *** scarcity of colonization and disease in the early months of life suggests thus that defense against mucosai carriage and invasive infection is above all provided by vertically acquired *** exposure of the neonates due to limited social contacts may also represent another factor avoiding neonates'mucosal Kingella kingae carriage.

关键词： Kingella kingae oropharyngeal carriage young infants

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