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Commentary on:“Human umbilical cord Wharton’s jelly-derived mesenchymal stem cell transplantation could improve diabetic intracavernosal pressure”

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Asian Journal of Andrology 2022年第2期24卷 226-227页

作者： Fotios Dimitriadis vasileios Palapelas Athanasios Zachariou Ioannis Sokolakis Department of Urology Aristotle UniversitySchool of MedicineThessalonikiGreece 3^(rd)Department of Obstetrics and Gynecology Aristotle UniversitySchool of MedicineThessalonikiGreece Department of Urology Ioannina UniversitySchool of MedicineIoanninaGreece Department of Urology Martha-Maria Hospital NurembergNurembergGermany

The article by Wu et al.1 is an interesting and meticulous work investigating the role of human umbilical cord Wharton’s jelly-derived mesenchymal stem cells(hWJ-MSCs)in the treatment of erectile dysfunction(ED)in th... 详细信息

关键词： diabetic al jelly

Forewordto the Special Issue on Nanomanufacturing and Atomic& Close-to-Atomic Scale Manufacturing (ACSM)

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Nanomanufacturing and Metrology 2022年第3期5卷 189-190页

作者： Nan Yu Stuart Reid Rebecca Cheung vasileios koutsos Institute for Materials and Processes The University of EdinburghEdinburgh EH89FBUK SUPA Department of Biomedical Engineering The University of StrathclydeGlasgow G11QEUK Institute for Integrated Micro and Nano Systems The University of EdinburghEdinburgh EH89FBUK

Nanomanufacturing(NM),developed over the past three decades,bridges nanosciencediscoveries tonanotechnology products by scaled-up,reliable,and cost-effective manufacturing materials,structures,devices,and systems at the nanoscale(1-100 nm).At this scale,physical and chemical properties of the materials and tools have been dominated by classical Newtonian mechanics,although quantum confinementeffects become *** of top-down and bottom-up approaches were developed,including nanomechanical machining,nanolithography,energy beam machining,deposition and etching,nanoprinting,nano assembly,nano replication,etc.[1].These techniques enabled a range of applications from medical imaging and renewable energy to sensor devices and quantum computing.

关键词： bridges printing machining

Homogenised Monthly and Daily Temperature and Precipitation Time Series in China and Greece since 1960

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Advances in Atmospheric Sciences 2023年第7期40卷 1326-1336页

作者： Athanassios A.ARGIRIOU Zhen LI vasileios ARMAOS Anna MAMARA Yingling SHI Zhongwei YAN Laboratory of Atmospheric Physics Department of PhysicsUniversity of PatrasRio 26504Greece key Laboratory of Regional Climate-Environment in Temperate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Hellenic National Meteorological Service Athens 16777Greece Longyang District Meteorological Service Baoshan 678007China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing 100049China

In this paper,we describe and analyze two datasets entitled“Homogenised monthly and daily temperature and precipitation time series in China during 1960–2021”and“Homogenised monthly and daily temperature and precipitation time series in Greece during 1960–2010”.These datasets provide the homogenised monthly and daily mean(TG),minimum(TN),and maximum(TX)temperature and precipitation(RR)records since 1960 at 366 stations in China and 56stations in *** datasets are available at the Science Data Bank repository and can be downloaded from https://***/10.57760/sciencedb.01731 and https://***/10.57760/*** China,the regional mean annual TG,TX,TN,and RR series during 1960–2021 showed significant warming or increasing trends of 0.27℃(10 yr)^(-1),0.22℃(10 yr)^(-1),0.35℃(10 yr)^(-1),and 6.81 mm(10 yr)-1,*** of the seasonal series revealed trends significant at the 0.05level,except for the spring,summer,and autumn RR *** Greece,there were increasing trends of 0.09℃(10 yr)-1,0.08℃(10 yr)^(-1),and 0.11℃(10 yr)^(-1)for the annual TG,TX,and TN series,respectively,while a decreasing trend of–23.35 mm(10 yr)^(-1)was present for *** seasonal trends showed a significant warming rate for summer,but no significant changes were noted for spring(except for TN),autumn,and *** RR,only the winter time series displayed a statistically significant and robust trend[–15.82 mm(10 yr)^(-1)].The final homogenised temperature and precipitation time series for both China and Greece provide a better representation of the large-scale pattern of climate change over the past decades and provide a quality information source for climatological analyses.

关键词： daily and monthly temperature precipitation homogenisation climate time series Greece China

Ocular stem cells:a narrative review of current clinical trials

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International Journal of Ophthalmology(English edition) 2022年第9期15卷 1529-1537页

作者： konstadinos Sotiropulos Dimitrios kourkoutas Diamantis Almaliotis katherine Ploumidou vasileios karampatakis Department of Ophthalmology 417 Army Shared Fund HospitalAthens 11521Greece Department of Ophthalmology 401 Army General Hospital of AthensAthens 11525Greece Laboratory of Experimental Ophthalmology School of MedicineAristotle University of ThessalonikiThessaloniki 54124Greece Department of Otolaryngology Children’s Hospital“Aglaia Kyriakou”Athens 11527Greece

·Stem cells are undifferentiated cells showcasing a remarkable capacity of self-replenishing and differentiating into mature *** ability to proliferate connotes that a designated stem cell source is capable of generating an unrestricted number of mature *** ever-increasing comprehension of position,activity,and function of ocular stem cells has led to rapid progress and incessant improvement of possible procedures and therapies.A narrative review was conducted to summarize the current evidence on clinical trials and respective literature,regarding current evolution in the field of ocular regenerative *** tried to ascertain the safety of experimental and clinical procedures,their effectiveness,and the ethical repercussion of their use.

关键词： stem cells cell-based therapies limbal stem cells h ESC-derived retinal pigment epithelium human induced pluripotent stem cells olfactory mucosa mesenchymal stem cells

Primary adrenal Ewing sarcoma:A systematic review of the literature

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世界临床病例杂志 2023年第28期11卷 6782-6791页

作者： Dimitrios k Manatakis Ioannis Tsouknidas Emmanouil Mylonakis Nikolaos Tasis Maria Ioanna Antonopoulou vasileios Acheimastos Aikaterini Mastoropoulou Dimitrios P korkolis 2^(nd)Department of Surgery Athens Naval and Veterans HospitalAthens 11521Greece General Surgery Lankenau Medical CenterMain Line HealthWynnewoodPA 19096United States Department of Surgical Oncology St Savvas Cancer HospitalAthens 11522Greece Department of Surgery Naval Hospital of CreteChania 73200Greece Department of Pediatrics Stony Brook University HospitalStony BrookNY 11794United States

BACkGROUND Ewing sarcoma(ES)is a malignant neoplasm of neuroectodermal origin and is commonly observed in children and young *** musculoskeletal system is the main body system impacted and ES is rarely seen in the visceral organs particularly the adrenal *** To present a comprehensive review of primary adrenal ES,with emphasis on diagnosis,therapy and oncological *** A systematic review of the literature was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses ***/MEDLINE,EMBASE and Google Scholar bibliographic databases were searched to identify articles from 1989 to 2022 and included patients with ES/primitive neuroectodermal tumor(PNET)of the adrenal ***,Google Scholar and EMBASE medical databases were searched,combining the terms“adrenal”,“ES”and“PNET”.Demographic,clinical,pathological and oncological data of patients were analyzed by SPSS version *** A total of 52 studies were included for review(47 case reports and 5 case series)with 66 patients reported to have primary adrenal *** age at diagnosis was 26.4±15.4 years(37.9%males,57.6%females,sex not reported in 3 cases).The most frequent complaint was abdominal/flank pain or discomfort(46.4%)followed by a palpable mass(25.0%),and the average duration of symptoms was 2.6±3.1 *** imaging modality of choice was computed tomography scan(81.5%),followed by magnetic resonance imaging(20.4%).Preoperative staging revealed that 17 tumors(27.9%)were metastatic and 14 patients had inferior vena cava or renal vein neoplastic thrombus at initial *** adrenalectomy was performed in the majority of cases(80.0%),of which 27.9%required more extensive *** invasive surgery was attempted in 8.2%of *** surgical resection was achieved in 89.4%of the *** therapy was administered to 32 patients,in the form of chemotherapy(62.5%),radiotherapy(3.1%)or combination(34.4%).Median overall s

关键词： Ewing sarcoma Primary adrenal tumor Adrenalectomy

Prospects of Huygens’ Metasurfaces for Antenna Applications

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Engineering 2022年第4期8卷 21-26页

作者： George V.Eleftheriades Minseok kim vasileios G.Ataloglou Ayman H.Dorrah Department of Electrical and Computer Engineering University of TorontoTorontoON M5S 3G8Canada

*** In recent years,there has been an intense research effort by the international community in the field of“artificial”electromagnetic materials,or“metamaterials.”Metamaterials are engineered structures that induce a tailored arrangement of magnetic and electric dipole moments when excited by an incident electromagnetic *** certain conditions,such as when the comprising unit cells are sub-wavelength,metamaterials can be homogenized and described in terms of macroscopic constitutive parameters such as permeability,permittivity,and refractive index.A summary of the early work on“artificial dielectrics”can be found in Ref.[1].In the over 20-year-old field of metamaterials,the desired macroscopic parameters correspond to extreme properties such as negative permittivity,negative permeability,and a negative refractive *** the most recognized metamaterial is that which realizes a negative refractive index,originally demonstrated at microwaves and based on a unit cellmade out of a split-ring resonator and a wire[2].In the engineering community,a transmission-line approach was developed for implementing metamaterials with significant advantages,such as reduced transmission losses and wider operating bandwidths[3,4].

关键词： refractive arrangement artificial

Polymer graph neural networks for multitask property learning

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npj Computational Materials 2023年第1期9卷 1420-1429页

作者： Owen Queen Gavin A.McCarver Saitheeraj Thatigotla Brendan P.Abolins Cameron L.Brown vasileios Maroulas konstantinos D.Vogiatzis Department of Mathematics University of TennesseeKnoxvilleTN 37996-1320USA Department of Electrical Engineering and Computer Science University of TennesseeKnoxvilleTN 37996-2250USA Department of Chemistry University of TennesseeKnoxvilleTN 37996-1600USA Eastman Chemical Company KingsportTN 37660USA

The prediction of a variety of polymer properties from their monomer composition has been a challenge for material informatics,and their development can lead to a more effective exploration of the material *** this work,POLYMERGNN,a multitask machine learning architecture that relies on polymeric features and graph neural networks has been developed towards this *** provides accurate estimates for polymer properties based on a database of complex and heterogeneous polyesters(linear/branched,homopolymers/copolymers)with experimentally refined *** POLYMERGNN,each polyester is represented as a set of monomer units,which are introduced as molecular graphs.A virtual screening of a large,computationally generated database with materials of variable composition was performed,a task that demonstrates the applicability of the POLYMERGNN on future studies that target the exploration of the polymer ***,a discussion on the explainability of the models is provided.

关键词： properties space polyester

Comparison between upfront surgery and neoadjuvant chemotherapy in patients with locally advanced gastric cancer:A systematic review

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世界胃肠外科杂志:英文版(电子版) 2023年第8期15卷 1808-1818页

作者： Stylianos Fiflis Menelaos Papakonstantinou Alexandros Giakoustidis Gregory Christodoulidis Eleni Louri vasileios N Papadopoulos Dimitrios Giakoustidis A’Department of Surgery General Hospital PapageorgiouThessaloniki 56429Greece Department of General Surgery University Hospital of LarissaLarissa 41110Greece

BACkGROUND Gastric cancer(GC)is a major health concern *** resection and chemotherapy is the mainstay treatment for gastric carcinoma,however,the optimal approach remains unclear and should be different in each *** can be administered both pre-and postoperatively,but a multidisciplinary approach is preferred when *** is particularly relevant for locally advanced GC(LAGC),as neoadjuvant chemotherapy(NAT)could potentially lead to tumor downsizing thus allowing for a complete resection with curative *** though the recent progress has been impressive,European and International guidelines are still controversial,thus attenuating the need for a more standardized approach in the management of locally advanced *** To investigate the effects of NAT on the overall survival(OS),the disease-free survival(DFS),the morbidity and the mortality of patients with LAGC in comparison to upfront surgery(US).METHODS For this systematic review,a literature search was conducted between November and February 2023 in PubMed,Cochrane Library and *** for studies including patients with *** independent reviewers conducted the research and extracted the data according to predetermined inclusion and exclusion *** Preferred Reporting Items for Systematic Reviews and Meta-Analyses was used to form the search strategy and the study protocol has been registered in the International Prospective Register of Systematic *** Eighteen studies with 4839 patients with LAGC in total were included in our systematic *** were separated into two groups;one receiving NAT before the gastrectomy(NAT group)and the other undergoing upfront surgery(US group).The OS ranged from 41.6%to 74.2%in the NAT group and from 30.9%to 74%in the US *** DFS was also longer in the NAT group and reached up to 80%in certain *** complications related to the chemotherapy or the surgery ranged from 6.4%to 38.1%in

关键词： Gastric cancer Locally advanced gastric cancer Neoadjuvant chemotherapy Surgery Survival

Fracturing process and effect of fracturing degree onwave velocity of a crystalline rock

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Journal of Rock Mechanics and Geotechnical Engineering 2017年第5期9卷 797-806页

作者： Charalampos Saroglou vasileios kallimogiannis Department of Geotechnical Engineering School of Civil Engineering National Technical University of Athens Athens Greece

The present paper investigates the effect of fracturing degree on P-and S-wave velocities in *** deformation of intact brittle rocks under loading conditions is characterized by a microcracking procedure,which occurs due to flaws in their microscopic structure and propagates through the intact rock,leading to shear *** fracturing process is of fundamental significance as it affects the mechanical properties of the rock and hence the wave *** order to determine the fracture mechanism and the effect of fracturing degree,samples were loaded at certain percentages of peak strength and ultrasonic wave velocity was recorded after every *** fracturing degree was recorded on the outer surface of the sample and quantified by the use of the indices P;（traces of joints/m）,P;（traces of joints/m;） and P;（length of fractures/m;）.It was concluded that the wave velocity decreases exponentially with increasing fracturing ***,the fracturing degree is described adequately with the proposed ***,other parameters concerning the fracture characteristics,rock type and scale influence were found to contribute to the velocity decay and need to be investigated further.

关键词： Wave velocity Fracturing Crack initiation Damage Granite