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Multi-clustering study on the association between human leukocyte antigen-DP-DQ and hepatitis B virus-related hepatocellular carcinoma and cirrhosis in Viet Nam

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World Journal of Gastroenterology 2024年第46期30卷 4880-4903页

作者： Thuy Thu Nguyen Tu Cam Ho Huong Thi Thu Bui van-khanh tran Tue Trong Nguyen Center for Gene and Protein Research Hanoi Medical UniversityHanoi 116177Viet Nam Institute of Virology TUM School of MedicineTechnical University of MunichMunich 81675Germany Department of Biochemistry Thai Nguyen University of Medicine and PharmacyThai Nguyen 251540Viet Nam Medical Technology Department Hanoi Medical UniversityHanoi 116177Viet Nam Clinical Laboratory Hanoi Medical University HospitalHanoi 116177Viet Nam

BACKGROUND Human leukocyte antigen(HLA)class II molecules are cell surface receptor proteins found on antigen-presenting *** and mutations in the HLA gene can affect the immune system and the progression of hepatitis *** To study the relation between rs2856718 of HLA-DQ,rs3077,and rs9277535 of HLA-DP,hepatitis B virus(HBV)-related cirrhosis,and hepatocellular carcinoma(HCC).METHODS In this case-control study,the genotypes of these single nucleotide polymorphisms(SNPs)were screened in 315 healthy controls,471 chronic hepatitis B patients,250 patients with HBV-related liver cirrhosis,and 251 patients with HCC using TaqMan real-time *** conducted Hardy-Weinberg equilibrium and linkage disequilibrium tests on the genotype distributions of rs2856718,rs3077,and rs9277535 before hierarchical clustering analysis to build the complex interaction between the markers in each patient *** The physical distance separating these SNPs was 29816 kB with the disequilibrium(D’)values ranging from 0.07 to *** close linkage between rs3077 and rs9277535 was attributed to a distance of 21 *** D’value decreased from moderate in the healthy control group(D’=0.50,P<0.05)to weak in the hepatic disease group(D’<0.3,P<0.05).In a combination of the three variants rs2856718,rs3077,and rs9277535,the A allele decreased hepatic disease risk[A-A-A haplotype,risk ratio(RR)=0.44(0.14;1.37),P<0.05].The G allele had the opposite effect[G-A/G-G haplotype,RR=1.12(1.02;1.23),P<0.05].In liver cancer cases,the A-A-A/G haplotype increased the risk of HCC by 1.58(P<0.05).CONCLUSION Rs9277535 affects liver fibrosis progression due to HBV infection,while rs3077 is associated with a risk of HBVrelated *** link between rs2856718,rs3077,and rs9277535 and disease risk was determined using a multiclustering analysis.

关键词： Human leukocyte antigen Multi-clustering study Hepatitis B virus Hepatocellular carcinoma Cirrhosis

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Health behavior outcomes in stroke survivors prescribed wearables for atrial fibrillation detection stratified by age

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Journal of Geriatric Cardiology 2024年第3期21卷 323-330页

作者： Joanne Mathew Jordy Mehawej Ziyue Wang Taylor Orwig Eric Ding Andreas Filippaios Syed Naeem Edith Mensah Otabil Alex Hamel Kamran Noorishirazi IrinaRadu Jane Saczynski David D.McManus khanh-van tran Division of Cardiovascular Medicine Department of MedicineUniversity of Massachusetts Chan Medical SchoolLake Avenue NorthWorcesterUSA Department of Internal Medicine Central Michigan UniversityMount PleasantUSA Department of Pharmacy and Health Systems Sciences School of PharmacyNortheastern UniversityBostonUSA Department of Population and Quantitative Health Sciences University of Massachusetts Chan Medical SchoolLake Avenue NorthWorcesterUSA

BACKGROUND Smartwatches have become readily accessible tools for detecting atrial fibrillation(AF).There remains limited data on how they affect psychosocial outcomes and engagement in older *** examine the health behavior outcomes of stroke survivors prescribed smartwatches for AF detection stratified by *** We analyzed data from the Pulsewatch study,a randomized controlled trial that enrolled patients(≥50 years)with a history of stroke or transient ischemic attack and CHA2DS2-VASc≥*** participants were equipped with a cardiac patch monitor and a smartwatch-app dyad,while control participants wore the cardiac patch monitor for up to 44 *** evaluated health behavior parameters using standardized tools,including the Consumer Health Activation Index,the Generalized Anxiety Disorder questionnaire,the 12-Item Short Form Health Survey,and wear time of participants categorized into three age groups:Group 1(ages 50-60),Group 2(ages 61-69),and Group 3(ages 70-87).We performed statistical analysis using a mixedeffects repeated measures linear regression model to examine differences amongst age *** Comparative analysis between Groups 1,2 and 3 revealed no significant differences in anxiety,patient activation,perception of physical health and wear *** use of smartwatch technology was associated with a decrease in perception of mental health for Group 2 compared to Group 1(β=-3.29,P=0.046).CONCLUSION Stroke survivors demonstrated a willingness to use smartwatches for AF ***,among these study participants,the majority did not experience negative health behavior outcomes or decreased engagement as age increased.

关键词： prescribed stratified wear

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Calculation of the ex-core neutron noise induced by individual fuel assembly vibrations in two PWR cores

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Nuclear Science and Techniques 2016年第4期27卷 67-77页

作者： Kiet A.T.Hoang van-Chung Cao van-khanh Hoang hoai-nam tran Institute of Research and Development Duy Tan University K7/25 Quang Trung Da Nang Vietnam American Polytechnic College Trung Son KDC Binh Chanh HCMC Vietnam Research and Development Center for Radiation Technology VINATOM Thu Duc HCMC Vietnam Faculty of Physics and Engineering Physics VNUHCM University of Science HCMC Vietnam Institute for Nuclear Science and Technology VINATOM 179 Hoang Quoc Viet Hanoi Vietnam

Calculation of the neutron noise induced by fuel assembly vibrations in two pressurized water reactor(PWR) cores has been conducted to investigate the effect of cycle burnup on the properties of the ex-core detector noise. An extension of the method and the computational models of a previous work have been applied to two different PWR cores to examine a hypothesis that fuel assembly vibrations cause the corresponding peak in the auto power spectral density(APSD) increase during the cycle. Stochastic vibrations along a random two-dimensional trajectory of individual fuel assemblies were assumed to occur at different locations in the cores. Two models regarding the displacement amplitude of the vibrating assembly have been considered to determine the noise source. Then, the APSD of the ex-core detector noise was evaluated at three burnup steps. The results show that there is no monotonic tendency of the change in the APSD of ex-core detector; however, the increase in APSD occurs predominantly for peripheral assemblies. When assuming simultaneous vibrations of a number of fuel assemblies uniformly distributed over the core, the effect of the peripheral assemblies dominates the ex-core neutron *** behaviour was found similar in both cores.

关键词：燃料组件随机振动中子噪声计算模型压水堆堆芯功率谱密度压水反应堆

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Development of a PARCS/Serpent model for neutronics analysis of the Dalat nuclear research reactor

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Nuclear Science and Techniques 2021年第2期32卷 32-44页

作者： Viet-Phu tran Kien-Cuong Nguyen Donny Hartanto Hoai-Nam tran Vinh Thanh tran van-khanh Hoang Pham Nhu Viet Ha Institute for Nuclear Science and Technology(INST) Vietnam Atomic Energy Institute(VINATOM)179 Hoang Quoc Viet str.Cau Giay DistrictHanoi 100000Vietnam Nuclear Research Institute(NRI) Vietnam Atomic Energy Institute(VINATOM)01 Nguyen Tu LucDalatLamdong 670000Vietnam Department of Mechanical and Nuclear Engineering University of SharjahPO.BOX 27272SharjahUnited Arab Emirates Institute of Fundamental and Applied Sciences Duy Tan UniversityHo Chi Minh city 700000Vietnam Faculty of Natural Science Duy Tan UniversityDanang 550000Vietnam Nuclear Safety Division Technical Support Center for Radiation and Nuclear Safety and Emergency ResponseVietnam Agency for Radiation and Nuclear Safety(VARANS)113 Tran Duy Hung str.Cau Giay DistrictHanoi 100000Vietnam

Cross-sectional homogenization for full-core calculations of small and complex reactor configurations,such as research reactors,has been recently recognized as an interesting and challenging *** paper presents the development of a PARCS/Serpent model for the neutronics analysis of a research reactor type TRIGA Mark-II loaded with Russian VVR-M2 fuel(known as the Dalat Nuclear Research Reactor or DNRR).The full-scale DNRR model and a supercell model for a shim/safety rod and its surrounding fuel bundles with the Monte Carlo code Serpent 2 were proposed to generate homogenized fewgroup cross sections for full-core diffusion calculations with *** full-scale DNRR model with Serpent 2 was also utilized as a reference to verify the PARCS/Serpent *** of the effective neutron multiplication factors,radial and axial core power distributions,and control rod worths showed a generally good agreement between PARCS and Serpent *** addition,the discrepancies between the PARCS and Serpent 2 results are also ***,the results indicate the applicability of the PARCS/Serpent model for further steady state and transient analyses of the DNRR.

关键词： PARCS Serpent 2 Group constant DNRR

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Knowledge and attitude toward COVID-19 among healthcare workers at District 2 Hospital, Ho Chi Minh City

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Asian Pacific Journal of Tropical Medicine 2020年第6期13卷 260-265页

作者： Huynh Giao Nguyen Thi Ngoc Han tran van khanh Vo Kim Ngan Vo van Tam Pham Le An Faculty of Public Health University of Medicine and Pharmacy at Ho Chi Minh CityVietnam Department of Infectious Diseases University Medical Center Ho Chi Minh CityVietnam Department of Scientific Research District 2 HospitalHo Chi Minh CityVietnam Department of Nursing District 2 HospitalHo Chi Minh CityVietnam Faculty of Nursing and Medical Technology University of Medicine Pham Ngoc Thach at Ho Chi Minh CityVietnam Center for the Training of Family Medicine Faculty of MedicineUniversity of Medicine and Pharmacy at Ho Chi Minh CityVietnam

Objective:To assess the knowledge and attitude toward coronavirus disease-2019(COVID-19)among healthcare workers at District 2 Hospital in Ho Chi Minh City(HCMC).Methods:A cross-sectional study was performed between January 2020 and February 2020 at District 2 Hospital.A systematic random sampling strategy was carried out and the data was collected through a self-administered questionnaire of the knowledge and attitude of healthcare workers regarding *** analysis was reported to describe the demographic,mean knowledge and attitude score of healthcare *** statistics including t-test,ANOVA and Spearman’s correlation were used to evaluate the relationship between study ***:A total of 327 eligible healthcare workers had a mean score of knowledge and attitude of 8.17±1.3(range 4-10)and 1.86±0.43(range 1-5),*** showed good knowledge and a positive ***,approximately two thirds of the participants knew the mode of transmission,the isolation period and treatment(67.0%,65.8%,and 58.4%,respectively),and 82.3%and 79.8%,respectively,held positive attitude regarding the risk of personal and family members getting *** was a negative correlation between knowledge scores and attitude scores(r=-0.21,P<0.001).Additionally,healthcare workerspredominately used social media to inform themselves about COVID-19(91.1%).Conclusions:The majority of healthcare workers had good knowledge and positive attitude toward ***,the level of some knowledge and attitude lower than that expected for their position level towards the *** education interventions and campaigns are required for healthcare workers.

关键词： Knowledge Attitude COVID-19 Healthcare worker District 2 Hospital

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Vibration characteristics of sandwich plates with an auxetic honeycomb core and laminated three-phase skin layers under blast load

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Defence Technology（防务技术） 2023年第6期24卷 148-163页

作者： Quoc-Hoa Pham van Ke tran Trung Thanh tran Faculty of Engineering and Technology Nguyen Tat Thanh UniversityHo Chi Minh CityViet Nam Faculty of Mechanical Engineering Le Quy Don Technical UniversityHanoiViet Nam

In this article,vibration characteristics of sandwich plates with an auxetic honeycomb core and laminated three-phase skin layers subjected to blast load are ***-order ES-MITC3 element based on higher-order shear deformation theory(HSDT)to achieve the governing *** sandwich plates with the ultra-light feature of the auxetic honeycomb core layer(negative Poisson’s ratio)and reinforced by two laminated three-phase skin *** obtained results in our work are compared with other previously published to confirm accuracy and *** addition,the effects of parameters such as geometrical and material parameters on the vibration characteristics of sandwich plates with an auxetic honeycomb core and laminated three-phase skin layers are fully investigated.

关键词： Laminated three-phase Sandwich plate Auxetic honeycomb ES-MITC3 element High-order shear deformation theory

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Structural and luminescent properties of (Eu,Tb) PO_4·H_2O nanorods/nanowires prepared by microwave technique

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Journal of Rare Earths 2011年第12期29卷 1170-1173页

作者： Nguyen Thanh Huong Nguyen Duc van Dinh Manh Tien Do khanh Tung Nguyen Thanh Binh tran Kim Anh Le Quoc Minh Institute of Materials Science Vietnam Academy of Science and Technology University of Engineering and Technology National University HanoiVietnam

Nanowires/nanorods of europium/terbium orthophosphate monohydrate with Eu^3＋ concentration of 6, 11, and 20 at.% were prepared by microwave synthesis method. The effects of Eu^3＋ doping concentration on structure, morphology and optical properties of nanomaterials were also investigated. The results showed that, for all studied Eu^3＋ doping concentrations, a single-crystalline phase of rhabdophane-type （Eu,Tb）PO4·H2O nanowires/nanorods was obtained by using microwave heating of an aqueous solution of terbium（Ⅲ） nitrate, europium（Ⅲ） nitrate and NH4H2PO4 with pH=2. The length and width of these nanowires/nanorods ranged from 150 to 300 nm and from 10 to 50 nm, respectively. The evidence of energy transfer from Tb^3＋ to Eu^3＋ due to the energy overlap between the donor Tb^3＋ and the acceptor Eu^3＋was observed obviously via a significant enhancement in the luminescent intensity of Eu^3＋. Keywords：

关键词： microwave technique nanowires/nanorods energy transfer fluorescence spectroscopy rare earths

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A comparative analysis of weight-based machine learning methods for landslide susceptibility mapping in Ha Giang area

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Big Earth Data 2023年第4期7卷 1005-1034页

作者： Thanh Trinh Binh Thanh Luu trang Ha Thi Le Duong Huy Nguyen Trong van tran Thi Hai van Nguyen khanh Quoc Nguyen Lien Thi Nguyen Faculty of Computer Science Phenikaa UniversityYen NghiaHa DongHanoi 12116Vietnam Phenikaa Research and Technology Institute(PRATI) A&A Green Phoenix Group JSCNo.167 Hoang NganTrung HoaCau GiayHanoi 11313Vietnam Northwestern Geological Division General Department of Geology and Minerals of VietnamHanoiVietnam Youth union office Thuyloi University175 Tay SonDong DaHanoiVietnam Center of Remote Sensing and Geohazards Vietnam Institute of Geosciences and Mineral ResourcesHanoiVietnam

Landslide susceptibility maps (LSMs) are very crucial for planningpolicies in hazardous areas. However, the accuracy and reliability ofLSMs depend on available data and the selection of suitable *** study is conducted to produce LSMs by combinations of machinelearning methods and weighting techniques for Ha Giang province,Vietnam, where has limited data. In study area, we gather 11 landslideconditioning factors and establish a landslide inventory *** the weights of classes (or factors) is very important toprepare data for machine learning methods to generate LSMs. Wefrst use frequency ratio (FR) and analytic hierarchy process (AHP)techniques to generate the weights. Then, random forest (RF), supportvector machine (SVM), logistic regression (LR), and AHP methods arecombined with FR and AHP weights to yield accurate and reliableLSMs. Finally, the performance of these methods is evaluated by fivestatistical metrics, ROC and R-index. The empirical results have shownthat RF is the best method in terms of R-index and the five metrics, *** rate (0.9661), FP rate (0.0), ACC (0.9835), MAE (0.0046), and RMSE(0.0350) for this study area. This study opens the perspective of weightbasedmachine learning methods for landslide susceptibility mapping.

关键词： Landslide logistic regression random forest SvM Vietnam

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Enhanced Intrusion Detection System for an EH IoT Architecture Using a Cooperative UAV Relay and Friendly UAV Jammer

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IEEE/CAA Journal of Automatica Sinica 2021年第11期8卷 1786-1799页

作者： van Nhan Vo Hung tran Chakchai So-In Institute of Research and Development Duy Tan UniversityDa Nang 550000Vietnam Faculty of Information Technology Duy Tan UniversityDa Nang 550000Vietnam Applied Network Technology Laboratory Department of Computer ScienceFaculty of ScienceKhon Kaen UniversityKhon Kaen 40002Thailand Faculty of Computer Science Phenikaa UniversityHanoi 100000Vietnam

In this paper,the detection capabilities and system performance of an energy harvesting(EH)Internet of Things(Io T)architecture in the presence of an unmanned aerial vehicle(UAV)eavesdropper(UE)are *** communication protocol is divided into two *** the first phase,a UAV relay(UR)cooperates with a friendly UAV jammer(UJ)to detect the UE,and the UR and UJ harvest energy from a power beacon(PB).In the second phase,a ground base station(GBS)sends a confidential signal to the UR using non-orthogonal multiple access(NOMA);the UR then uses its harvested energy to forward this confidential signal to IoT destinations(IDs)using the decode-and-forward(DF)***,the UJ uses its harvested energy to emit an artificial signal to combat the detected UE.A closed-form expression for the probability of detecting the UE(the detection probability,DP)is derived to analyze the detection ***,the intercept probability(IP)and throughput of the considered IoT architecture are ***,we identify the optimal altitudes for the UR and UJ to enhance the system and secrecy *** Carlo simulations are employed to verify our approach.

关键词： Detection probability(DP) energy harvesting(EH) friendly UAV jammer Internet of Things(IoT) system performance UAV detection

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LiMn_2O_4/CNTs and LiNi_(0.5)Mn_(1.5)O_4/CNTs Nanocomposites as High-Performance Cathode Materials for Lithium-Ion Batteries

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Acta Metallurgica Sinica(English Letters) 2015年第1期28卷 122-128页

作者： Thang van Le Ha tran Nguyen Anh Tuan Luu Man van tran Phung Loan My Le Faculty of Materials Technology Ho Chi Minh University of Technology 268 Ly Thuong Kiet Ward 14 District 10 Ho Chi Minh City Vietnam Department of Physical Chemistry University of Science VNUHCM 227 Nguyen Van Cu Street District 5 Ho Chi Minh CityVietnam

The demand of higher energy density and higher power capacity of lithium（Li）-ion secondary batteries has led to the search for electrode materials whose capacities and performance are better than those available today. Carbon nanotubes（CNTs）, with their unique properties such as 1D tubular structure, high electrical and thermal conductivities, and extremely large surface area, have been used as materials to prepare cathodes for Li-ion batteries. The structure and morphology of CNTs were analyzed by X-ray diffraction（XRD）, scanning electron microscopy（SEM）, and transmission electron microscopy（TEM）. The functional groups on the purified CNT surface such as –COOH, –OH were characterized by Fourier transform infrared spectroscopy. The electrode materials were fabricated from LiMn2O4（LMO）, doped spinel LiNi0.5Mn1.5O4, and purified CNTs via solid-state reaction. The structure and morphology of the electrode were characterized using XRD, SEM, and TEM. Finally, the efficiency of the electrode materials using CNTs was evaluated by cyclic voltammetry and electrochemical impedance spectroscopy.

关键词： Nanocomposites Carbon nanotubes(CNTs) Spinel materials Lithium-ion batteries(LIBs)

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