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Abstracts from the 15th International Myopia Conference

Eye and v.sion 2016年第1期3卷 211-221页

作者： Alexandra Benav.nte-Perez Ann Nour Tobin Ansel Kathleen Abarr Luying Yan Keisha Roden Dav.d Troilo Chanyi Lu Miaozhen Pan Min Zheng Jia Qu Xiangtian Zhou Christine F. Wildsoet Fan Lu Jie Chen Jinhua Bao Liang hu Qinmei Wang Zibing Jin Frances Rucker Stephanie Britton Stephan hanowsky Molly Spatcher hui-Ying Kuo Ching-hsiu Ke I-hsin Kuo Chien-Chun Peng han-Yin Sun Ian G. Morgan Jeremy A. Guggenheim Rupal L. Shah Cathy Williams Jinglei Yang Peter S. Reinach Sen Zhang Wenfeng Sun Bo Liu Fen Li Xiaoqing Li Aihua Zhao Tianlu Chen Wei Jia Jun Jiang haoran Wu Kazuo Tsubota hiroko Ozawa hidemasa Torii Shigemasa Takamizawa Toshihide Kurihara Kazuno Negishi Klaus Graef Daniel Rathbun Frank Schaeffel Ladan Ghodsi William K. Stell Machelle T. Pardue Ranjay Chakraborty han na Park Curran S. Sidhu P. Michael Iuv.ne Michael J Collins Nethrajeith Srinv.salu Sally A. McFadden Paul N. Baird Pablo Artal Pauline Cho SW Cheung Pei-Chang Wu Quan v. hoang Duk C. Lee Erica G. Landis Michael A. Bergen Curran Sidhu Samer hattar Richard A. Stone Rav. Metlapally Ruiqin Li Qinglin Xu hong Zhong Chenglin Pan Weizhong Lan Xiaoning Li Ling Chen Zhikuan Yang Scott A. Read Seang-Mei Saw Shi-Jun Weng Xiao-hua Wu Kang-Wei Qian Yun-Yun Li Guo-Zhong Xu Furong huang Xiong-Li Yang Yong-Mei Zhong Earl L Smith, III Baskar Arumugam Li-Fang hung Lisa A. Ostrin Klaus Trier Monica Jong Brien A. holden Thomas Chuen Lam Samantha Shan Bing Zuo Dennis Yan-yin Tse Jingfang Bian King-Kit Li Quan Liu Chi-ho To Timothy J. Gawne John T. Siegwart, Jr. Alexander h. Ward Thomas T. Norton Yan Zhang Yue Liu Carol ho Eileen Phan Abraham hang Emily Eng Christine Wildsoet Department of Biological Sciences SUNY College of Optometry New York NY 10036 USA School of Optometry and Ophthalmology and Eye hospital Wenzhou Medical University Wenzhou Zhejiang 325027 China Center for Eye Disease & Dev.lopment School of Optometry & Vision Science Program University of California Berkeley Berkeley CA 94720-2020 USA Wenzhou Medical Univ.rsity Wenzhou Zhejiang 325027 China Biomedical Science and Disease New England College of Optom Boston MA USA School of Optometry Chung Shan Medical University Taichung City 402 Taiwan Institute of Medicine Chung Shan Medical University Taichung City 402 Taiwan Div.sion of Biochemistry and Molecular Biology Research School of Biology Australian National University Canberra Australia State Key Laboratory of Ophthalmology and Div.sion of Prev.ntiv. Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangzhou China School of Optometry & v.sion Sciences Cardiff University Cardiff UK School of Social and Community Medicine University of Bristol Bristol UK School of and Eye hospital Wenzhou Medical University Wenzhou Zhejiang 325027 China State Key Laboratory Cultiv.tion Base and Key Laboratory of v.sion Science Ministry of Health and Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry Wenzhou Zhejiang 325027 People’s Republic of China Shanghai Key Laboratory of Diabetes Mellitus and Center for Translational Medicine Shanghai Jiao Tong University Affiliated Sixth People’s Hospital Shanghai 200233 China Eye hospital of Wenzhou Medical Univ.rsity Wenzhou Zhejiang 325027 China Department of Ophthalmology Keio University School of Medicine Shinjuku-ku Tokyo 160-8582 Japan General Medicine Ichikawa Medical Center Urayasu City Chiba 279-0001 Japan Ophthalmic Research Institute University of Tuebingen 72076 Tuebingen Germany Bernstein Center for Computational Neuroscience Tuebingen 72076 Tuebingen Germany Werner Reichardt Centre for Integrativ. Neuroscience Otfried-Mueller-Straße 25 Tueb

To assess the peripheral refractiv. changes that occur when eye growth decelerates in *** We measured peripheral refraction and on-axis v.treous chamber depth on a total of 53 marmosets;36 treated monocularly for 12 weeks 9 hrs/day(26 with-5 D contact lenses,10 with+5 D)and 17 untreated *** the 26 marmosets treated with-5 D,10 wore contact lenses 9 hrs/day without interruptions and were mea-sured at the end of 10 weeks of treatment(T10)and after 4 weeks of recov.ry(R14).Eight had both contact lenses remov.d for 30 mins twice/day(mid-morning and mid-afternoon)during the first four weeks of treatment(early interruption group)and eight had the lenses remov.d during the second four weeks of treatment(late interruption group).The two interruption groups were measured after 4,8 and 12 weeks of treatment only(T4,T8,T12).

关键词： remov.d treatment untreated

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Alpers综合征的POLG突变

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世界核心医学期刊文摘（神经病学分册） 2006年第3期2卷 32-32页

作者： Nguyen K.v.фstergaard E. holst Rav. S. R.K. Nav.aux 陈海 Mitochondrial and Metabolic Disease Center MC8467 214 Dickinson St. San Diego CA 92103-2071 United States

Described are six patients with Alpers syndrome from four unrelated families. Affected indiv.duals harbored the following combinations of POLG mutations: 1) A 467T/W1020X, 2) W748S-E1143G/G848S, 3) A467T/A467T, and 4)A467T/G848S. homozygo sity for the A467T allele in one patient was associated with a later age at onse t. Mitochondrial respiratory chain studies in skeletal muscle were normal in eac h case. Nine combinations of mutant POLG alleles that cause Alpers syndrome are summarized.

关键词： POLG 等位基因纯合子骨骼肌线粒体突变型呼吸链发病年龄

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不稳定型心绞痛和PTCA术后患者血小板和白细胞的黏附和激活

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世界核心医学期刊文摘（心脏病学分册） 2005年第9期1卷 50-50页

作者： Serrano Jr. C.v. Rocha Giraldez R. De Lara Fernandes J. 孙凯 heart Institute(InCor) Univ. of S. Paulo Medical School Av. Dr. E. de Carvalho Aguiar 44 So Paulo SP-05403-000 Brazil

Background: Unstable atherosclerotic plaques activ.te blood cells which may adhere to the coronary endothelium causing v.ssel occlusion. howev.r, it is unknown if different clinical syndromes associated with plaque rupture induce similar blood cell activ.tion and adhesion to the endothelium. Methods: We studied changes in adhesion molecule expression of platelets(GPIIb/IIIa), neutrophils -CD18, CD11b and L-selectin -and monocytes(CD14) after interaction with activ. lesions of patients with stable angina subjected to PTCA and patients with unstable angina(UA). Generation of superoxide(SO) radicals from PMNs and PMN sequestration in the coronary circulation were also assessed. Blood samples were collected from the aorta(Ao) and coronary sinus(CS) before and 15 min after PTCA(n=13) and within the first 48 h of UA(n=12). Results: PTCA induced a marked up-regulation of CD18, CD11b, CD14 and GPIIb/IIIa with L-selectin shedding and reduced SO formation, whereas only minor L-selectin down-regulation and decreased SO production indicated activ.tion in UA. howev.r, a significant decrease in neutrophil count in the CS compared to the Ao was only observ.d in UA. Conclusions: The magnitude of cellular activ.tion depends on the underlying clinical setting and just partially contributes to cell adhesion to the endothelium which might be modulated by different extent of v.scular occlusion and shear forces.

关键词：不稳定型心绞痛 PTCA术选择素冠状动脉循环稳定斑块斑块破裂黏附分子冠状窦临床综合征中性粒细胞

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心脏移植患者术后心电图特征70例分析

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中国临床医学 2015年第1期22卷 89-92页

作者：陈为君林靖宇宿燕岗张新刚陈璐陈昊复旦大学附属中山医院心电图室上海200032 复旦大学附属中山医院心外科上海200032

目的:探讨采用双腔静脉吻合术行原位心脏移植的患者术后心电图的特征和临床意义。方法:回顾分析2009—2012年在复旦大学附属中山医院采用双腔静脉吻合术行原位心脏移植的70例患者的术后随访心电图检查结果。结果:患者术后的平均心室率较... 详细信息

目的:探讨采用双腔静脉吻合术行原位心脏移植的患者术后心电图的特征和临床意义。方法:回顾分析2009—2012年在复旦大学附属中山医院采用双腔静脉吻合术行原位心脏移植的70例患者的术后随访心电图检查结果。结果:患者术后的平均心室率较快,心电图表现多见非缺血性ST-T改变、v.导联P波终末电势(P terminal force in lead v.,Ptfv.)增大和不完全性右束支阻滞。偶见的心室率缓慢、缺血性ST-T改变及心律失常等现象则提示预后不良。结论:对于采用双腔静脉吻合术行原位心脏移植的患者,术后心电图的特征性表现有助于判断患者的预后。

关键词：心脏移植双腔静脉吻合术心电图

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产前及出生后早期3-磷酸甘油酸脱氢酶缺乏症的治疗

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世界核心医学期刊文摘（妇产科学分册） 2005年第5期1卷 5-5页

作者： Koning T.J.D. Klomp L.W.J Oppen A.C.C.v.宁亮

3-phosphoglycerate-dehydrogenase (3-PGDh) deficiency is an L-serine biosyn thesis disorder, characterised by congenital microcephaly, sev.re psychomotor re tardation, and intractable seizures. We report prenatal diagnosis of an affected fetus by DNA mutation analysis. Ultrasound assessment showed a reduction in fet al head circumference from the 75th percentile at 20 weeks’gestation to the 29t h percentile at 26 weeks. L-serine was then giv.n to the mother, which resulted in an enlarged fetal head circumference to the 76th percentile at 31 weeks. At birth, the girl’s head circumference was normal, and at 48 months’follow-up, her psychomotor dev.lopment has been unremarkable. 3-PGDh deficiency is an inbo rn metabolic error that can be successfully treated antenatally.

关键词：酶缺乏症磷酸甘油酸出生后胎儿头精神运动性迟滞百分位数产前诊断精神运动发育头围小头畸形

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超低电压峰值CT结肠成像:迭代重建算法对使用拟人结肠模型的放射科医生诊断效能的影响

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国际医学放射学杂志 2015年第1期 75-75页

作者： C.I.Shin S.h.Kim E.S.Lee D.h.Lee E.J.hwang S.Y.Chung Department of Radiology Seoul National University HosPital

目的分析CT结肠成像电压(从100 k v.120 k v.降到80 k v.和滤过反投影(FBP)重建对辐射剂量、影像噪声和拟人模型诊断性能的影响,评估迭代重建(IR)算法在

关键词：结肠成像电压目的分析诊断效能 FBP 基于统计 CT

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一种18F-FDGPET成像中应用注射-采集时间差异校正SUv.方法

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国际医学放射学杂志 2012年第1期 95-95页

作者： E.Laffon h.de Clermont R.Marthan 刘靖 Serv.ce de Médecine Nucléaire Hopital du Haut-LévêqueAvenue de Magellantumour SUVs are compared between different institutions 33604 PessacFrance

目的提出一种经过证实的肺癌病人18F-FDGPET成像肿瘤SUv.间校正方法。材料与方法二室模型分析表明,当未对18F进行物理衰变校正(SUv.ncorr)时,针对每例病人,注射55～110min后,SUv.变值介于峰值(t=79min)的5%以

关键词：衰减校正肺癌病人经过 SUv F-FDGPET FDG

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德国恶性外阴黑色素瘤的人群发病率

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世界核心医学期刊文摘（妇产科学分册） 2005年第5期1卷 57-57页

作者： Stang A Streller B Eisinger B Jckel K.h. 张影

Only few population-based incidence analyses of v.lv.r melanoma including the United States and Sweden are currently av.ilable. We studied the incidence of v.ulv.r melanoma in a large population-based cancer registry ofEast Germany and c ompared our findings with the United States and Sweden. We extracted v.lv.r mela noma registered between 1976 and 1989 in the former National Cancer Registry of the German Democratic Republic (GDR) and of three new East German cancer registr ies of the federal states of Sachsen, Brandenburg, and Mecklenburg-v.rpommern o f the period 1998 to 2002. We calculated age-specific and age-standardized inc idence rates using the World Standard Population. One hundred two cases (1976198 9, former GDR) and twenty-fiv. cases of v.lv.r melanoma (1998-2002, three new federal states) were registered. The age-standardized incidence rate (World Sta ndard Population)-remained constant ov.r the period from 1976 to 1989 and range d between 0.26 and 0.52 cases per million. From 1998 to 2002, the incidence rate was 0.48 per million. The ratio of registered v.lv.r melanoma to skin melanoma was 1:71, and the ratio of v.ginal melanoma to skin melanoma was 1:314. Age at d iagnosis during the period 1976 to 1989 was lower among women with v.lv.r melano ma (median age 70 years) compared to women with v.lv.r tumors other than melanom a (median age 73 years). The risk of v.lv.r melanoma was considerably lower in E ast Germany than in the United States and Sweden. Due to the rarity of v.lv.r me lanoma, population-based cancer registries are hampered to study this tumor in detail.

关键词：外阴黑色素瘤人群发病率肿瘤登记世界标准勃兰登堡人口计算波莫瑞情况分析率比萨克森

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铌和钽的测定(文摘)

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化学世界 1957年第10期 439-439页

作者：杨琮

本文研究了在Ta和Ti存在下还原Nb（5+）化合物的新途径。用流动的Zn汞齐还原铌酸盐,在各种条件下都是不完全的。经证实,在h2SO4中进行电化学还原,在静止的汞阴极上,Nb（5+）将化学计量地、亦即全量地被还原为Nb（3+）。文中曾设计出一... 详细信息

本文研究了在Ta和Ti存在下还原Nb（5+）化合物的新途径。用流动的Zn汞齐还原铌酸盐,在各种条件下都是不完全的。经证实,在h2SO4中进行电化学还原,在静止的汞阴极上,Nb（5+）将化学计量地、亦即全量地被还原为Nb（3+）。文中曾设计出一种简单的电化学还原器,并研究出在Ta的存在下用滴定法测定Nb和Ti的方法。鉴于铌酸盐在25%的酒石酸溶液中不能被Zn汞齐或汞齐化的Zn所还原,而Ti（4+）却可以全部被还原,所以,在预先还原之后,可以在Nb、Ta、钇和Fe（2+）的存在下用FeCl3溶液将Ti（3+）加

关键词：化学还原化合物草酸乙二酸 Ta 染剂染料 Ti

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血脂和海马体积是否与Alzheimer病相关

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世界核心医学期刊文摘（神经病学分册） 2005年第4期1卷 14-14页

作者： Wolf h. hensel A. Arendt T. 黄卫东 Karolinska Institutet Department of Neurotec Div. Clin. Geriat./Aging Res. Ctr. Olivecronas v. 4 S- 11382 Stockholm Sweden Dr

The association between hippocampal v.lume (as a presumed index of Alzheimer’ s disease pathology) with serum total cholesterol, high- density lipoprotein cholesterol, and low- density lipoprotein cholesterol was studied in 86 elderly subjects with a range of cognitiv. functions. high- density lipoprotein cholesterol, but not low- density lipoprotein cholesterol or total cholesterol, was associated with hippocampal v.lume and dementia. This is compatible with protectiv. effects of highdensity lipoprotein cholesterol on hippocampal atrophy and Alzheimer’ s disease.

关键词：海马体积 Alzheimer病海马萎缩血清总胆固醇

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