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Midline Spinal Cord Hamartomas—A Report of Six Cases

International Journal of Clinical Medicine 2013年第6期4卷 291-295页

作者： Damera Naveen Chandra Rao vallabhaneni kalyan chakravarthy Eslavath Aruna Gundala Venkata Ratnam Diddi Ranga Rao Department of Pathology Pinnamaneni Siddhartha Institute of Medical Sciences & Research Foundation Chinna Avutapalli India Department of Pathology Pinnamaneni Siddhartha Institute of Medical Sciences & Research Foundation Chinna Avutapalli India.

Midline Spinal Cord Hamartomas are relatively rare and asymptomatic. These lesions may present with a tethered cord and a normal overlying skin, a skin dimple, a dermal sinus tract or dense collagen. Most patients have few or no neurological symptoms related to them. Microscopically they are composed of mature and well-differentiated ectodermal and mesodermal elements, meningothelial cells, calcification, and even urothelium. We report MRI and histologic features of midline spinal cord hamartomas in six cases.

关键词： Hamartoma Meningothelial Cells Ectodermal

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Role of Allergy in Sinonasal Polyposis

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International Journal of Otolaryngology and Head & Neck Surgery 2012年第1期1卷 1-6页

作者： Mahesh Chandra Hegde Vennela Burra kalyan chakravarthy Burra Department Of Community Medicine Dr. Pinnamaneni Siddhartha Institute of Medical Sciences & Research Foundation Chinoutpally. Gannavaram India Department of ENT & Head & Neck Surgery Dr. Pinnamaneni Siddhartha Institute of Medical Sciences & Research Foundation Chinoutpally. Gannavaram India Department of ENT & Head & Neck Surgery Kasturba medical College Mangalore India

Objectives: The exact role of allergy in sinonasal polyposis is not yet clearly elucidated and is undoubtedly a contro-versial subject. The study focussed on the association of allergy in nasal polyposis. We aim to determine whether there was a correlation between Serum IgE, absolute eosinophil count, eosinophilic inflammation, and nasal polyps. Methods: A study group of fifty two consecutive patients of nasal polyposis were evaluated prospectively and compared with 26 controls who underwent septoplasty and mimimal FESS or Endoscopic Sphenopalatine artery ligation. Patients were evaluated for presence of allergy with regard to absolute eosinophil count, total serum IGE and tissue eosinophilia and correlations were established. All patients were categorized based on histological evidence of tissue eosinophilia. Re-sults: The incidence of asthma was 5.8% and positive history of allergy was obtained in 40.4% of patients in study group and 7.7% of patients in control group. The statistically significant association was not seen with absolute eosino-phil count, Serum IgE and tissue eosinophilia. Tissue eosinophilia was observed in more number of patients with nasal polyposis compared to controls. So clinical significance might be established. Conclusions: Allergy is parameter that is frequently associated with this disease, irrespective of the type of polyp and the age at presentation. Unrecognized and untreated allergy adds to the morbidity of the disease and generally results in poor treatment outcome.

关键词： Allergy Nasal Polyps Serum IgE Absolute Eosinophil Count Tissue Eosinophilia

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Bilateral Tibial Xanthoma in a Normolipidemic Patient—Report of a Rare Case with Review of Literature

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International Journal of Clinical Medicine 2012年第3期3卷 234-237页

作者： vallabhaneni kalyan Chakravarthi E. Aruna Damera Naveen Chandra Rao Diddi Ranga Rao Department of Pathology Dr.PSIMS & RF Chinna Avutapalli India.

Xanthoma of bone is a rare benign bone disorder. It radiologically presents as a lytic lesion, often with cortical expansion or disruption, mimics primary bone tumors and metastatic lesions. Histopathological study gives the definitive diagnosis. Xanthoma of bilateral tibia in a normolipidemic patient is rare and not yet reported in literature. Here with we present one such rare case, with review of literature.

关键词： Xanthoma Normolipidic Tibia Lytic Lesion

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