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Cluster Analysis of the Roma-BZCAT Blazars

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Research in Astronomy and Astrophysics 2024年第5期24卷 117-139页

作者： Dmitry O.Kudryavtsev Yulia v.Sotnikova vladislav A.Stolyarov Timur v.Mufakharov valery v.vlasyuk Margarita L.Khabibullina Alexander G.Mikhailov Yulia v.Cherepkova Special Astrophysical Observatory of the Russian Academy of Sciences Nizhny Arkhyz 369167Russia Astrophysics Group Cavendish LaboratoryUniversity of CambridgeCambridge CB3 OHEUK Kazan Federal University 18 Kremlyovskaya StKazan 420008Russia

Based on the collected multiwavelength data, namely in the radio(NvSS, FIRST, RATAN-600), IR(WISE),optical(Pan-STARRS), Uv(GALEX), and X-ray(ROSAT, Swift-XRT) ranges, we have performed a cluster analysis for the blazars of the Roma-BZCAT catalog. Using two machine learning methods, namely a combination of PCA with k-means clustering and Kohonen's self-organizing maps(SOMs), we have constructed an independent classification of the blazars(five classes) and compared the classes with the known Roma-BZCAT classification(FSRQs, BL Lacs, galaxy-dominated BL Lacs, and blazars of an uncertain type) as well as with the high synchrotron peaked(HSP) blazars from the 3HSP catalog and blazars from the TevCat catalog. The obtained groups demonstrate concordance with the BL Lac/FSRQ classification along with a continuous character of the change in the properties. The group of HSP blazars stands out against the overall distribution. We examine the characteristics of the five groups and demonstrate distinctions in their spectral energy distribution shapes. The effectiveness of the clustering technique for objective analysis of multiparametric arrays of experimental data is demonstrated.

关键词： methods data analysis-galaxies active-(galaxies:)BL Lacertae objects general

Spherically Symmetric Problem of General Relativity for a Fluid Sphere

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Journal of Modern Physics 2024年第4期15卷 401-415页

作者： valery v. vasiliev Leonid v. Fedorov Institute of Applied Mechanics of Russian Academy of Sciences Moscow Russia

The paper is devoted to a spherically symmetric problem of General Relativity (GR) for a fluid sphere. The problem is solved within the framework of a special geometry of the Riemannian space induced by gravitation. According to this geometry, the four-dimensional Riemannian space is assumed to be Euclidean with respect to the space coordinates and Riemannian with respect to the time coordinate. Such interpretation of the Riemannian space allows us to obtain complete set of GR equations for the external empty space and the internal spaces for incompressible and compressible perfect fluids. The obtained analytical solution for an incompressible fluid is compared with the Schwarzchild solution. For a sphere consisting of compressible fluid or gas, a numerical solution is presented and discussed.

关键词： General Relativity Spherically Symmetric Problem Fluid Sphere

Introduction to the special issue on celebrating the 15th anniversary of JIOHS and the 70th anniversary of HUST

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Journal of Innovative Optical Health Sciences 2023年第1期16卷 1-4页

作者： Qingming Luo valery v.Tuchin Lihong Wang Hainan University P.R.China Wuhan NationalLabforOptoelectronics HUSTP.R.China Institute of Precision Mechanics and Control FRC SSC RASRussia A.N.Bach Institute of Biochemistry FRC Fundamentals of Biotechnology RAS Russia California Institute of Technology USA

Since launching in 2008,Journal of Innovative Optical Health Sciences(JIOHS)has been published for 15 years umtil *** by the founding advisor *** Chance and other founding Editorial Members,JIOHS was quickly embraced by the biomedical optics community,especially in *** submitted some of their high quality papers to JIOHS,which led to a constant Impact Factor(IF)increase frcom the first IF 0.632 to IF 2396(Journal Citation Report 2021).

关键词： founding optics OHS

Advances in small animal mesentery models for in vivo flow cytometry,dynamic microscopy,and drug screening

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World Journal of Gastroenterology 2007年第2期13卷 192-218页

作者： Ekaterina I Galanzha valery v Tuchin vladimir P Zharov Philips Classic Laser Laboratories University of Arkansas for Medical Sciences (UAMS) Little Rock AR United States Department of Optics and Biomedical Physics Research-Educational Institute of Optics and Biophotonics Saratov State University Saratov Russia Department of Optics and Biomedical Physics Research-Educational Institute of Optics and Biophotonics Saratov State University Saratov Russia Philips Classic Laser Laboratories University of Arkansas for Medical Sciences (UAMS) Little Rock AR United States

Using animal mesentery with intravital optical microscopy is a well-established experimental model for studying blood and lymph microcirculation in vivo. Recent advances in cell biology and optical techniques provide the basis for extending this model for new applications, which should generate significantly improved experimental data. This review summarizes the achievements in this specific area, including in vivo label-free blood and lymph photothermal flow cytometry, super-sensitive fluorescence image cytometry, light scattering and speckle flow cytometry, microvessel dynamic microscopy, infrared (IR) angiography, and high-speed imaging of individual cells in fast flow. The capabilities of these techniques, using the rat mesentery model, were demonstrated in various studies; e.g., real-time quantitative detection of circulating and migrating individual blood and cancer cells, studies on vascular dynamics with a focus on lymphatics under normal conditions and under different interventions (e.g. lasers, drugs, nicotine), assessment of lymphatic disturbances from experimental lymphedema, monitoring cell traffic between blood and lymph systems, and high-speed imaging of cell transient deformability in flow. In particular, the obtained results demonstrated that individual cell transportation in living organisms depends on cell type (e.g., normal blood or leukemic cells), the cell’s functional state (e.g., live, apoptotic, or necrotic), and the functional status of the organism. Possible future applications, including in vivo early diagnosis and prevention of disease, monitoring immune response and apoptosis, chemo- and radio-sensitivity tests, and drug screening, are also discussed.

关键词： Lymph microcirculation Transmission digital microscopy Rat mesentery Flow cytometry Photothermal technique

Shedding light on biology and healthcare--preface to the special issue on Biomedical Optics

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Light(Science & Applications) 2022年第7期11卷 1315-1317页

作者： Peng Xi Xunbin Wei Junle Qu valery v.Tuchin Department of Biomedical Engineering College of Future TechnologyPeking University100871BeijingChina Department of Biomedical Engineering Peking University100081BeijingChina Center for Biomedical Optics and Photonics(CBOP)&College of Physics and Optoelectronic Engineering Key Laboratory of Optoelectronic Devices and Systems of Guangdong Province and Ministry of EducationShenzhen University518060ShenzhenChina Saratov State University 83 Astrakhanskaya str.Saratov410012Russia

During the past decade,there has been an explosion in the development of novel optical techniques in biomedical research and clinical *** progress has been made in optical imaging and detection to provide necessary biological information for disease diagnosis and in-depth understanding of biological ***,recent advances integrating laser technology with biomarkers have enabled novel diagnostic and treatment approaches for different types of diseases.

关键词： optical integrating diagnosis

INTRODUCTION:SPECIAL ISSUE ON ADvANCES IN BIOPHOTONICS AND BIOMEDICAL OPTICS-PART I

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Journal of Innovative Optical Health Sciences 2013年第2期6卷 16-17页

作者： Dan Zhu valery v.Tuchin Qingming Luo Huazhong University of Science and Technology WuhanP.R.China Saratov State University SaratovRussia

The 5th Russian-Chinese Workshop on Biophotonics and Biomedical Optics was hosted in Saratov,Russia on 26-28,September,*** bilateral Workshop brought together both Russian and Chinese scientists,engineers and clinical researchers from a variety of disciplines engaged in applying optical science,photonics and imaging technologies to problems in biology and *** the W orkshop,2 plenary lectures,11 invited presentations,4 oral presentations and 13 poster reports were presented.A special Internet session with 5 presentations-1 plenary,2 invited,and 2 posters was also *** special issue selects some papers from the attendees,and is made up of 12 original research articles and one *** articles will be presented in vol.6 No.1 of JIOHS,while the remaining five articles will be presented in vol.6 No.2.

关键词： Russian photonics engineer

OPTICAL PROPERTIES OF SKIN,SUBCUTANEOUS,AND MUSCLE TISSUES:A REvIEW

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Journal of Innovative Optical Health Sciences 2011年第1期4卷 9-38页

作者： ALEXEY N.BASHKATOv ELINA A.GENINA valery v.TUCHIN Institute of Optics and Biophotonics Saratov State University Saratov 410012Russia Institute of Precise Mechanics and Control of RAS Saratov 410028Russia

The development of optical methods in modern medicine in the areas of diagnostics,therapy,and surgery has stimulated the investigation of optical properties of various biological tissues,since the efficacy of laser treatment depends on the photon propagation and fluence rate distribution within irradiated *** this work,an overview of published absorption and scattering properties of skin and subcutaneous tissues measured in wide wavelength range is *** principles of measurements of the tissue optical properties and techniques used for processing of the measured data are outlined.

关键词： Absorption coefficient scattering coefficient anisotropy factor reduced scattering coefficient refractive index

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FOREWORD

Journal of Innovative Optical Health Sciences 2009年第1期2卷 I0001-I0002页

作者： Elina A.Genina Kirill v.Larin valery v.Tuchin Research-Educational Institute of Optics and Biophotonics Saratov State University Saratov Russia Department of Biomedical Engineering University of Houston Houston USA Research-Educational Institute of Optics and Biophotonics Saratov State University Institute of Precise Mechanics and Control RAS Saratov Russia

Special Issue Optical Technologies in the Study of Tissues and Biological Fluids We are pleased to present this special issue of JIOHS,which focuses on optical technologies in the study of tissues and biological *** selected papers were presented during Saratov Fall Meeting—XII International School for Junior Scientists and Students on Optics,Laser Physics and Biophotonics(September 23–26,2008,Saratov,Russia)in the framework of the following workshops:“Optical Technologies in Biophysics and Medicine,”“Nanostructures and Nanoparticles,”“Microscopic and Low-Coherence Methods in Biomedical Applications,”and“Internet Biophotonics.”All eight papers in this special issue are research papers.

关键词： Junior photonics Russia

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Foreword to the Special Issue on Optical Technologies in Biophysics and Medicine

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Journal of Innovative Optical Health Sciences 2015年第3期8卷 1-2页

作者： Elina A.Genina Dan Zhu valery v.Tuchin Research-Educational Institute of Optics and Biophotonics Saratov State University SaratovRussia Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology(HUST)Wuhan P.R.China Research-Educational Institute of Optics and Biophotonics Saratov State University Institute of Precise Mechanics and Control RAS Saratov Russia

We are pleased to present the third issue of JIOHS,which focuses on optical technologies of diagnosticsand therapy,These are selected papers presented during Saratov Fall Meeting,1t International Sym-posium on Optics and Biophotonics(September 24-28,2013,Saratov,Russia)in the framework of the Workshops:"Optical Technologies in Biophysics_and Medicine,"Nanobiophotonics,"and"Internet Biophotonics."

关键词： Biophys ics photonics