检索结果-南通市图书馆

A Five-Year Experience of Sparing Treatment of Descending Aortic Atherosclerotic Aneurysms

World Journal of Cardiovascular Surgery 2016年第4期6卷 47-54页

作者： Vladimir Petrovich Krylov Alexander Gennadyevich Mrochek valentina nukolaevna gayduk Leonid Ivanovich Reut Aleksey Leonidovich Smaliakou Nadezhda Vladimirovna Mankevich Roman Nikolaevich Pizhik Republican Research and Practical Centre “Cardiology” Ministry of Health of the Republic of Belarus Minsk Belarus

A growing number of specialists are now beginning to ascertain that treatment of individuals with descending aortic atherosclerotic aneurysms must be provided by cardiologists on a scheduled basis. Surgery is feasible when there is a risk of aneurysm rupture. It requires for the development of conservative treatments and elaboration of indications for surgery. A total of 97 patients with thoracic aortic atherosclerotic aneurysms (TAAA) and abdominal aortic aneurysms (AAA) have been examined over a 5-year period. They received multifaceted anti-inflammatory medical treatment to strengthen the aortic wall and control its possible expansion. Operative treatment was offered only if there was a risk of aneurysm rupture. One of the principal factors adversely affecting mortality is the presence of co-morbidities requiring permanent medical corrective treatment irrespective of surgical or medical treatment provided. It is also important to outline the indications for surgery based on multifactorial pathogenetic manifestations. Treatment aiming at the reversal of ethiopathogenic mechanisms of disease progression contributes to a significant longer survival in DAA patients.

关键词： Aortic Atherosclerotic Aneurysms Surgical Treatment Conservative Treatment Outcomes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Long-Term Results (Seven and More Years) of Sparing Treatment of Subjects with Descending Aortic Aneurysms

引用

Health 2019年第6期11卷 661-670页

作者： Vladimir Petrovich Krylov Dmitry Evgeniyevich Shevtsov Gennadiy Adolfovich Popel valentina Nikolaevna gayduk Leonid Ivanovich Reut Aleksey Leonidovich Smaliakou Nadezhda Vladimirovna Mankevich Republican Research and Practical Centre of Cardiology Minsk Belarus Belarusian Association of Physicians Ministry of Health of Belarus Minsk Belarus

Descending aortic aneurysms (DAAs), including dissecting aneurysms (DA) have a multifactorial etiology and pathogenesis, therefore raising questions about the leading role of operative treatment to repair the lesion. Objective: To investigate remote (7 and more years) results of treatment in patients with DAAs in operative treatment only if there is a danger of aneurysm rupture. A total of 82 patients with atherosclerotic DAA identified between 2008 and 2011, and 22 patients with type 1 or 3 DeBakey dissecting aneurysms (DA) who had not been operated in the acute period due to a number of reasons were examined. The follow-up period of these groups was 7 or more years. When using a sparing treatment to treat DAA, we saw survival of 90.1 at 2 years, 76.8% at 4 years, 59.4% at 6 years, and 57.5% at 7 years with the uniform increase in mortality rate, mainly due to a comorbidity. Survival in DA group (77.3%) was better due to a younger age and was 68.4% in operated and 54% in non-operated patients at 7 years. It is symptomatic that the aneurysm rupture rate was not always affected by operative treatment. Therefore, it seems like medical treatment is more consistent with etiopathogenesis of the disease compared to surgery during the stabilization period.

关键词： Descending Aortic Aneurysms Medical and Surgical Treatment 7-Year Treatment Results Survival

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Role of Atherosclerosis and Inflammation in the Development of Descending Aortic Aneurysms: Special Aspects of Medical Correction

引用

Health 2016年第13期8卷 1335-1348页

作者： Vladimir Petrovich Krylov Nikolay Andreevich Mana Leonid Petrovich Titov valentina Nikolaevna gayduk Leonid Ivanovich Reut Nadezhda Vladimirovna Mankevich Alexander Stanislavovich Zhigalcovitch Aleksey Leonidovich Smolyakou Gennady Adolfovich Popel Roman Nikolaevich Pyzhyk Republican Scientific and Practical Centre “Cardiology” Ministry of Health of Belarus Minsk Belarus Republican Scientific and Practical Centre “Epidemiology and Microbiology” Ministry of Health of Belarus Minsk Belarus Belarusian Medical Academy of Post-Graduate Education Minsk Belarus

Modern medicine has achieved much progress in the field of medical and surgical repair of a variety of disorders. It is especially true for the early stages of treatments. In long-term period, however, instead of recovery, we frequently observe progressive regression, which completely annuls all our efforts. Moreover, the algorithm used to correct acute process may sometimes be detrimental to organs and tissues. Such situation is also frequent in the treatment of atherosclerotic descending aortic aneurysms (DAA). This is because the successful medical and even surgical repair to prevent aneurysm rupture in long-term period may trigger some detrimental processes in other regions thus producing negative results of the treatment. The present article doesn’t aim to prove some provisions in DAA clinical picture, atherosclerosis and inflammatory states. But we have faced some systematicity at these clinical implications which are absolutely not specified in literature. We have managed to find an explanation for this thing making a scrupulous analysis of nonsurgical sources. Comparing them with our observations, we have found out that aseptic and septic inflammation of connective tissue, probably, is a key component in the formation of DAA disregarding of which correction of dyslipidemia may lead to negative results. We are looking for in-depth research and discussion.

关键词： Aneurism Formation Atherosclerosis and Inflammation Aortic Aneurisms

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：