检索结果-南通市图书馆

Therapeutic strategies in Crohn’s disease in an emergency surgical setting

World Journal of Gastroenterology 2022年第18期28卷 1902-1921页

作者： Maria Michela Chiarello Gilda Pepe Valeria Fico valentina Bianchi Giuseppe Tropeano Gaia Altieri Giuseppe Brisinda Department of Surgery San Giovanni in Fiore HospitalAzienda Sanitaria Provinciale di CosenzaCosenza 87100Italy Emergency Surgery and Trauma Center Fondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy Department of Surgery Fondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy Medical and Surgical Science UniversitàCattolica del Sacro CuoreRome 00168Italy

Crohn’s disease(CD)remains a chronic,incurable disorder that presents unique challenges to the *** factors must be considered to allow development of an appropriate treatment *** therapy often precedes or complements the surgical *** indications for operative management of CD include acute and chronic disease complications and failed medical *** surgery comes into play when patients are refractory to medical treatment if they have an obstructive *** colitis,acute obstruction,perforation,acute abscess,or massive hemorrhage represent indications for emergency *** patients are generally in critical conditions and present with intra-abdominal sepsis and a preoperative status of immunosuppression and malnutrition that exposes them to a higher risk of complications and mortality.A multidisciplinary team including surgeons,gastroenterologists,radiologists,nutritional support services,and enterostomal therapists are required for optimal patient care and decision *** of each emergency should be individualized based on patient age,disease type and duration,and patient goals of ***,the recurrent nature of disease mandates that we continue searching for innovative medical therapies and operative techniques that reduce the need to repeat surgical *** this review,we aimed to discuss the acute complications of CD and their treatment.

关键词： Crohn’s disease Intestinal obstruction Free perforation Intra-abdominal sepsis Perineal sepsis Acute bleeding

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A comparative study of Salvia miltiorrhiza Radix & Rhizoma raw material and granule products using chromatographic analysis and antioxidant activity

引用

Journal of Traditional Chinese Medical Sciences 2022年第3期9卷 311-320页

作者： Xian Zhou valentina Razmovski-Naumovski Raynold Mendoza John Truong Kelvin Chan NICM Health Research Institute Western Sydney UniversityWestmead2145Australia South West Sydney Clinical Campuses Faculty of Medicine&HealthUniversity of New South WalesSydneyNSW2170Australia School of Pharmacy and Biomolecular Sciences Liverpool John Moores UniversityLiverpoolL33AFUK

Objective: Granules of herbal extracts are a popular medicinal preparation consumed in traditional Chinese medicine clinical practice. However, their quality and efficacy evaluation are lacking. This study aimed to compare the quality and anti-oxidant activity of Dan Shen(Salvia miltiorrhiza Radix & Rhizoma)granule extracts with their herbal ***: Chromatographic method was used to determine the content of 7 marker compounds in the water extracts of the herb compared to that of 12 granule extracts. Agglomerative hierarchical clustering(AHC) and principal component analysis(PCA) distinguished the herbal and granule extracts based on the content of the marker compounds. The antioxidant activities of herbal and granule extracts were evaluated by 2, 2'-azino-bis(3-ethylbenz-thiazoline-6-sulfonic acid)(ABTS), organic chemical compound 2,2-diphenyl-1-picrylhydrazyl(DPPH) and ferric ion reducing antioxidant power(FRAP) ***: The herbal extracts group showed significantly higher contents of salvianolic acid B, sodium danshensu and cryptotanshinone compared with that of the granule group. This corresponded to significantly higher ABTS, DPPH and FRAP(P <.05) activities of the herbal extracts. The AHC and PCA analysis distinguished granule extracts from most herbal extracts predominantly by the content of salvianolic acid ***: The results confirm the need for the assessment of granule products so that healthcare practitioners and consumers are better informed of their quality and efficacy.

关键词： Dan Shen Granule Multivariate analysis Salvia miltiorrhiza Radix&rhizoma Ultra-performance liquid chromatography Antioxidant

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

SARS-CoV-2 and the pancreas: What do we know about acute pancreatitis in COVID-19 positive patients?

引用

World Journal of Gastroenterology 2022年第36期28卷 5240-5249页

作者： Giuseppe Brisinda Maria Michela Chiarello Giuseppe Tropeano Gaia Altieri Caterina Puccioni Pietro Fransvea valentina Bianchi Department of Medical and Surgical Sciences Fondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy Department of Medicine and Surgery UniversitàCattolica del Sacro CuoreRome 00168Italy Department of Surgery Azienda Sanitaria Provinciale di CosenzaCosenza 87100Italy Emergency Surgery and Trauma Center Fondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)can cause pancreatic damage,both directly to the pancreas via angiotensin-converting enzyme 2 receptors(the transmembrane proteins required for SARS-CoV-2 entry,which are highly expressed by pancreatic cells)and indirectly through locoregional vasculitis and *** that,there is no clear evidence that SARS-CoV-2 is an etiological agent of acute *** pancreatitis in coronavirus disease 2019(COVID-19)positive patients often recognizes biliary or alcoholic *** prevalence of acute pancreatitis in COVID-19 positive patients is not exactly ***,COVID-19 positive patients with acute pancreatitis have a higher mortality and an increased risk of intensive care unit admission and necrosis compared to COVID-19 negative *** respiratory distress syndrome is the most frequent cause of death in COVID-19 positive patients and concomitant acute *** this article,we reported recent evidence on the correlation between COVID-19 infection and acute pancreatitis.

关键词： Acute pancreatitis SARS-CoV-2 Severe acute pancreatitis Multiparametric scores Infected necrosis Step-up approach

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Anastomotic leakage in rectal cancer surgery:Retrospective analysis of risk factors

引用

World Journal of Clinical Cases 2022年第36期10卷 13321-13336页

作者： Giuseppe Brisinda Maria Michela Chiarello Gilda Pepe Maria Cariati Valeria Fico Paolo Mirco valentina Bianchi Department of Medical and Surgical Sciences Fondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy Department of Surgery UniversitàCattolica S CuoreRome 00168Italy Department of Surgery Azienda Sanitaria Provinciale di CosenzaCosenza 87100Italy Emergency Surgery and Trauma Center Fondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy Department of Surgery Azienda Sanitaria Provinciale di CrotoneCrotone 88900Italy

BACKGROUND Anastomotic leakage(AL)after restorative surgery for rectal cancer(RC)is associated with significant morbidity and *** To ascertain the risk factors by examining cases of AL in rectal surgery in this retrospective cohort *** To identify risk factors for AL,a review of 583 patients who underwent rectal resection with a double-stapling colorectal anastomosis between January 2007 and January 2022 was ***,demographic and operative features,intraoperative outcomes and oncological characteristics were *** The incidence of AL was 10.4%,with a mean time interval of 6.2±2.1 *** mortality was 0.8%.Mortality was higher in patients with AL(4.9%)than in patients without leak(0.4%,P=0.009).Poor bowel preparation,blood transfusion,median age,prognostic nutritional index<40 points,tumor diameter and intraoperative blood loss were identified as risk factors for *** of anastomosis,number of stapler cartridges used to divide the rectum,diameter of circular stapler,level of vascular section,T and N status and stage of disease were also correlated to AL in our *** diverting ileostomy did not reduce the leak rate,while the use of the transanastomic tube significantly *** Clinical,surgical and pathological factors are associated with an increased risk of *** adversely affects the morbidity and mortality of RC patients.

关键词： Anastomosis Leak Anterior resection Morbidity Mortality Rectal surgery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Simulating bicycle traffic by the intelligent-driver model-Reproducing the traffic-wave characteristics observed in a bicycle-following experiment

引用

Journal of Traffic and Transportation Engineering(English Edition) 2020年第1期7卷 19-29页

作者： valentina Kurtc Martin Treiber Institute of Applied Mathematics and Mechanics Peter the Great St.Petersburg Polytechnic UniversitySt.Petersburg 195251Russia Institute for Transport and Economics Technische Universitat DresdenDresden 01062Germany

Bicycle traffic operations become increasingly important and yet are largely ignored in the traffic flow community,until *** hypothesize that there is no qualitative difference between vehicular and bicycle traffic flow dynamics in single-file case,so the latter can be described by reparameterized car-following *** test this proposition,we reproduce German(Andresen et al.,2014)and Chinese(Jiang et al.,2016)bicycle experiments on a ring with the intelligent-driver model(IDM)and compare its fit quality(calibration)and predictive power(validation)with that of the necessary-deceleration-model(NDM),which is specifically designed for bike *** find similar quality metrics for both models,so the above hypothesis of a qualitative equivalence cannot be ***,calibration errors of the IDM turn up to be slightly smaller compared to the NDM *** NDM represents significant calibration errors for high flow densities,which correspond to flow states,when stop-and-go wave *** to validation tests,the IDM outperforms the NDM as *** two types of validation techniques we discover that inter-driver variation is much higher than the intra-driver variation for bicycle *** coincides with the results obtained from vehicular traffic experiments(NGSIM trajectory data).In addition,we suggest the measure for quantitative comparison of two microscopic fundamental diagrams,which are derived from experimental data and simulated *** analysis of speed-density relations provides more or less the same results for both models.

关键词： Bicycle traffic Car-following model Stop-and-go waves Calibration Validation Fundamental diagram

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of COVID-19 on the liver:The experience of a single center

引用

World Journal of Gastroenterology 2022年第39期28卷 5735-5749页

作者： valentina Liakina Ieva Stundiene Gabriele Milaknyte Ramune Bytautiene Rosita Reivytyte Roma Puronaite Gintare Urbanoviciute Edita Kazenaite Centre of Hepatology Gastroenterology and DieteticsClinic of GastroenterologyNephrourology and SurgeryInstitute of Clinical MedicineFaculty of MedicineVilnius UniversityVilnius 01513Lithuania Department of Chemistry and Bioengineering Faculty of Fundamental SciencesVILNIUS TECHVilnius 10223Lithuania Faculty of Medicine Vilnius UniversityVilnius 01513Lithuania Clinic of Cardiac and Vascular Diseases Institute of Clinical MedicineFaculty of MedicineVilnius UniversityVilnius 01513Lithuania Institute of Data Science and Digital Technologies Faculty of Mathematics and InformaticsVilnius UniversityVilnius 01513Lithuania Department of Pathology Forensic Medicine and PharmacologyInstitute of Biomedical SciencesFaculty of MedicineVilnius UniversityVilnius 01513Lithuania

BACKGROUND The coronavirus disease 2019(COVID-19)was perhaps the most severe global health crisis in living *** respiratory symptoms,elevated liver enzymes,abnormal liver function,and even acute liver failure were reported in patients suffering from severe acute respiratory disease coronavirus 2 ***,the precise triggers of these forms of liver damage and how they affect the course and outcomes of COVID-19 itself remain *** To analyze the impact of liver enzyme abnormalities on the severity and outcomes of COVID-19 in hospitalized *** In this study,684 depersonalized medical records from patients hospitalized with COVID-19 during the 2020-2021 period were ***-19 was diagnosed according to the guidelines of the National Institutes of Health(2021).Patients were assigned to two groups:those with elevated liver enzymes(Group 1:603 patients),where at least one out of four liver enzymes were elevated(following the norm of hospital laboratory tests:alanine aminotransferase(ALT)≥40,aspartate aminotransferase(AST)≥40,gamma-glutamyl transferase≥36,or alkaline phosphatase≥150)at any point of hospitalization,from admission to discharge;and the control group(Group 2:81 patients),with normal liver enzymes during ***-19 severity was assessed according to the interim World Health Organization guidance(2022).Data on viral pneumonia complications,laboratory tests,and underlying diseases were also collected and *** In total,603(88.2%)patients produced abnormal liver test *** and AST levels were elevated by a factor of less than 3 in 54.9%and 74.8%of cases with increased enzyme levels,*** in Group 1 had almost double the chance of bacterial viral pneumonia complications[odds ratio(OR)=1.73,P=0.0217],required oxygen supply more often,and displayed higher biochemical inflammation indices than those in Group *** differences in other COVID-19 complications or underlying disea

关键词： COVID-19 SARS-CoV-2 Liver enzymes Complications Underlying disease Disease severity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Paradoxical association between dyspepsia and autoimmune chronic atrophic gastritis:Insights into mechanisms,pathophysiology,and treatment options

引用

World Journal of Gastroenterology 2023年第23期29卷 3733-3747页

作者： Roberta Elisa Rossi Alessandra Elvevi valentina Sciola Francesco Vito Mandarino Silvio Danese Pietro Invernizzi Sara Massironi Gastroenterology and Endoscopy Unit IRCCS Humanitas Research HospitalRozzano 20089MilanItaly Gastroenterology Unit Fondazione IRCCS San Gerardo dei TintoriMonza 20900Italy and Department of Medicine and SurgeryUniversity of Milano-BicoccaMonza 20900Italy Gastroenterology and Endoscopy Unit Fondazione IRCCS Ca’Granda Ospedale Maggiore PoliclinicoMilano 20100Italy Department of Gastroenterology and Endoscopy IRCCS Ospedale San RaffaeleMilan 20132Italy School of Medicine Vita-Salute San Raffaele UniversityMilan 20132Italy

BACKGROUND Autoimmune gastritis(AIG)is a progressive,chronic,immune-mediated inflammatory disease characterized by the destruction of gastric parietal cells leading to hypo/anacidity and loss of intrinsic *** symptoms such as dyspepsia and early satiety are very common,being second in terms of frequency only to anemia,which is the most typical feature of *** To address both well-established and more innovative information and knowledge about this challenging *** An extensive bibliographical search was performed in PubMed to identify guidelines and primary literature(retrospective and prospective studies,systematic reviews,case series)published in the last 10 *** A total of 125 records were reviewed and 80 were defined as fulfilling the *** AIG can cause a range of clinical manifestations,including *** pathophysiology of dyspepsia in AIG is complex and involves changes in acid secretion,gastric motility,hormone signaling,and gut microbiota,among other *** dyspeptic symptoms of AIG is challenging and there are no specific therapies targeting dyspepsia in *** proton pump inhibitors are commonly used to treat dyspepsia and gastroesophageal reflux disease,they may not be appropriate for *** agents,antidepressant drugs,and non-pharmacological treatments may be of help,even if not adequately evidence-based supported.A multidisciplinary approach for the management of dyspepsia in AIG is recommended,and further research is needed to develop and validate more effective therapies for dyspepsia.

关键词： Dyspepsia Dyspeptic symptoms Gastro-intestinal symptoms Autoimmune gastritis Chronic autoimmune atrophic gastritis Treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Artificial intelligence and its role in guiding liverdirected therapy for hepatocellular carcinoma:Is it ready for prime time?

引用

Hepatoma Research 2022年第1期8卷 466-481页

作者： Elena Panettieri Andrea Campisi valentina Bianchi Felice Giuliante Agostino Maria De Rose Hepatobiliary Surgery Unit Fondazione Policlinico Universitario Agostino Gemelli IRCCSUniversitàCattolica del Sacro CuoreRome 00168Italy Emergency and Trauma Surgery Unit Fondazione Policlinico Universitario Agostino Gemelli IRCCSUniversitàCattolica del Sacro CuoreRome 00168Italy

Artificial intelligence(AI)is an innovative discipline in medicine,impacting both hepatology and hepato-pancreatobiliary surgery,ensuring reliable outcomes because of its repeatable and efficient algorithms.A considerable number of studies about the efficiency of AI in the management of hepatocellular carcinoma(HCC)have been *** its diagnostic role is well recognized,providing large amounts of quantitative radiological HCC features,its use in HCC treatment is still *** use of AI may help to select the best approach for each patient as it is able to predict the outcomes after resection and/or other *** this review,we assess the role of AI in selecting the best therapeutic option and predicting long-term risks after surgical or interventional treatments for HCC *** studies are needed to consolidate AI applications.

关键词： Artificial intelligence precision medicine HCC hepatocellular carcinoma

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Lamb-dip saturated-absorption cavity ring-down rovibrational molecular spectroscopy in the near-infrared

引用

Photonics Research 2022年第8期10卷 1803-1809页

作者： ROBERTO AIELLO valentina DI SARNO MARIA GIULIA DELLI SANTI MAURIZIO DE ROSA IOLANDA RICCIARDI GIOVANNI GIUSFREDI PAOLO DE NATALE LUIGI SANTAMARIA PASQUALE MADDALONI Consiglio Nazionale delle Ricerche-Istituto Nazionale di Ottica Via Campi Flegrei 3480078 PozzuoliItaly Istituto Nazionale di Fisica Nucleare Sez.di NapoliComplesso Universitario di M.S.AngeloVia Cintia80126 NapoliItaly ppqSense S.r.l. Via Gattinella 2050013 Campi BisenzioItaly Consiglio Nazionale delle Ricerche-Istituto Nazionale di Ottica Largo E.Fermi 650125 FirenzeItaly Agenzia Spaziale Italiana Contrada Terlecchia75100 MateraItaly

The high-detection-sensitivity saturated-absorption cavity ring-down(SCAR)technique is extended to Lambdip spectroscopy of rovibrational molecular transitions in the near-infrared ***-comb-referenced sub-Doppler saturation measurements,performed on the acetylene(ν_(1)+ν_(3)+ν_(4)←ν_(4))R(14)e line at6562 cm^(-1),are analyzed by a SCAR global line profile fitting routine,based on a specially developed theoretical *** to a conventional cavity ring-down evaluation,our approach yields dip profiles with a linewidth freed from saturation broadening effects,reduced by 40%,and a signal-to-noise ratio increased by 90%.Ultimately,an overall(statistical and systematic)fractional uncertainty as low as 7×10^(-12)is achieved for the absolute line-center *** the same time,our method is also able to accurately infer the linear(nonsaturated)behavior of the gas absorption,providing Lamb-dip-based line strength measurements with a relative uncertainty of 0.5%.

关键词： saturated cavity absorption

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Patient-specific instrumentation in total ankle arthroplasty

引用

World Journal of Orthopedics 2022年第3期13卷 230-237页

作者： Antonio Mazzotti Alberto Arceri Simone Zielli Simone Bonelli valentina Viglione Cesare Faldini The First Orthopaedics and Traumatologic Clinic IRCCS Istituto Ortopedico RIzzoliBologna 40136Italy Department of Biomedical and Neuromotor Sciences Alma Mater Studiorum University of BolognaBologna 40136Italy

The recent increase in the adoption of total ankle arthroplasty(TAA)reflects the improvements in implant designs and surgical techniques,including the use of preoperative navigation system and patient-specific instrumentation(PSI),such as custom-made cutting *** guides are customized with respect to each patient's anatomy based on preoperative ankle computed tomography scans,and they drive the saw intra-operatively to improve the accuracy of bone resection and implant *** some promising results,the main queries in the literature are whether PSI improves the reliability of achieving neutral ankle alignment and more accurate implant sizing,whether it is actually superior over standard techniques,and whether it is cost ***,the advantages of PSI in clinical outcomes are still theoretical because the current literature does not allow to confirm its *** purpose of this review article is therefore to assess the current literature on PSI in TAA with regard to current implants with PSI,templating and preoperative planning strategies,alignment and sizing,clinical outcomes,cost analysis,and comparison with standard techniques.

关键词： Total ankle arthroplasty Total ankle replacement Patient-specific instrumentation Ankle computer navigation system Preoperative navigation Prophecy Infinity INBONE II

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：