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Bypassing major venous occlusion and duodenal lesions in rats, and therapy with the stable gastric pentadecapeptide BPC 157, L-NAME and L-arginine

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World Journal of Gastroenterology 2018年第47期24卷 5366-5378页

作者： Fedor Amic Domagoj Drmic Zdenko Bilic Ivan Krezic Helena Zizek Marina Peklic Robert Klicek Alen Pajtak Enio Amic Tinka Vidovic Mislav Rakic Marija Milkovic Perisa Katarina Horvat pavlov Antonio Kokot Ante Tvrdeic Alenka Boban Blagaic Mario Zovak Sven Seiwerth Predrag Sikiric Department of Pharmacology Medical Faculty University of Zagreb Department of Pathology Medical Faculty University of Zagreb

AIM To investigate whether duodenal lesions induced by major venous occlusions can be attenuated by BPC 157 regardless nitric oxide(NO) system *** Male Wistar rats underwent superior anterior pancreaticoduodenal vein(SAPDV)-ligation and were treated with a bath at the ligated SAPDV site(BPC 157 10 μg, 10 ng/kg per 1 mL bath/rat; L-NAME 5 mg/kg per 1 m L bath/rat; L-arginine 100 mg/kg per 1 mL bath/rat, alone and/or together; or BPC 157 10 μg/kg instilled into the rat stomach, at 1 min ligation-time). We recorded the vessel presentation(filled/appearance or emptied/disappearance) between the 5 arcade vessels arising from the SAPDV on the ventral duodenum side, the inferior anterior pancreaticoduodenal vein(IAPDV) and superior mesenteric vein(SMV) as bypassing vascular pathway to document the duodenal lesions presentation; increased NO-and oxidative stress [malondialdehyde(MDA)]-levels in *** Unlike the severe course in the SAPDV-ligated controls, after BPC 157 application, the rats exhibited strong attenuation of the mucosal lesions and serosal congestion, improved vessel presentation, increased interconnections, increased branching by more than 60% from the initial value, the IAPDV and SMV were not congested. Interestingly, after 5 min and 30 min of L-NAME and L-arginine treatment alone, decreased mucosal and serosal duodenal lesions were observed; their effect was worsened at 24 h, and no effect on the collateral vessels and branching was seen. Together, L-NAME+L-arginine antagonized each other's response, and thus, there was an NO-related effect. With BPC 157, all SAPDV-ligated rats receiving L-NAME and/or L-arginine appeared similar to the rats treated with BPC 157 alone. Also, BPC 157 in SAPDV-ligated rats normalized levels of NO and MDA, two oxidative stress markers, in duodenal *** BPC 157, rapidly bypassing occlusion, rescued the original duodenal flow through IAPDV to SMV flow, aneffect related to the NO system and

关键词： Major venous occlusion Duodenal lesions BPC 157 L-NAME Bypassing L-arginine Reduction of free radical formation Rats

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Highly efficient THz four-wave mixing in doped silicon

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Light(Science & Applications) 2021年第5期10卷 806-811页

作者： Nils Dessmann Nguyen H.Le Viktoria Eless Steven Chick Kamyar Saeedi Alberto Perez-Delgado Sergey G.pavlov Alexander F.G.van der Meer Konstantin L.Litvinenko Ian Galbraith Nikolay V.Abrosimov Helge Riemann Carl R.Pidgeon Gabriel Aeppli Britta Redlich Benedict N.Murdin Radboud University Institute for Molecules and MaterialsHFML-FELIXNijmegenThe Netherlands Advanced Technology Institute and Department of Physics University of SurreyGuildford GU27XHUK Institute of Optical Sensor Systems German Aerospace CenterBerinGermany Institute of Photonics and Quantum Sciences SUPAHeriot-Watt UniversityEdinburghUK Leibniz-Institut fur Kristallzuchtung(IKZ) BerlinGermany Laboratory for Solid State Physics ETH Zurich8093 ZurichSwitzerland Institut de Physique EPFL1015 LausanneSwitzerland Paul Scherrer Institute 5232 VlligenSwitzerland

Third-order non-linearities are important because they allow control over light pulses in ubiquitous high-quality centro-symmetric materials like silicon and *** four-wave mixing provides a direct measure of the third-order non-linear sheet susceptibility x^(3)(where L represents the material thickness)as well as technological possibilities such as optically gated detection and emission of *** picosecond pulses from a free electron laser,we show that silicon doped with P or Bi has a value of x^(3)Lin the THz domain that is higher than that reported for any other material in any wavelength *** immediate implication of our results is the efficient generation of intense coherent THz light via upconversion(also a x^(3)process),and they open the door to exploitation of nondegenerate mixing and optical nonlinearities beyond the perturbative regime.

关键词： mixing wave Highly

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俄罗斯再生铝的现状与贸易

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有色金属再生与利用 2005年第6期 24-26页

作者： Sergei pavlov 兰兴华

当今时代的特点是,中国经济持续多年快速发展,最近三年,这种发展又受到全球经济复苏和美国经济增长的促进.美国、中国和印度是经济增长的'发动机',2003年三国占世界GDP的40%.

关键词：再生铝俄罗斯贸易现状经济增长 2003年中国经济经济复苏发动机 GDP 美国

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载流子平衡方法提高量子点发光二极管效率的研究

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半导体光电 2020年第5期41卷 667-672页

作者：杨媚郑力为孟琪王鑫梁培袁晓霖唐莹 Sergei I.pavlov Pavel N.Brunkov 刘祖刚中国计量大学光学与电子科技学院杭州310018 中芯集成电路(宁波)有限公司浙江宁波315800 Ioffe物理技术研究所圣彼得堡194021

尝试采用三种方式来平衡载流子的浓度,以提高量子点发光二极管(QLED)的外量子效率等性能:在正装结构(ITO/HIL/HTL/QD/ETL/EIL/金属阴极)的QLED的发光层和电子传输层中间插入超薄聚甲基丙烯酸甲脂(PMMA)电子阻挡层;在空穴注入和传输层方... 详细信息

尝试采用三种方式来平衡载流子的浓度,以提高量子点发光二极管(QLED)的外量子效率等性能:在正装结构(ITO/HIL/HTL/QD/ETL/EIL/金属阴极)的QLED的发光层和电子传输层中间插入超薄聚甲基丙烯酸甲脂(PMMA)电子阻挡层;在空穴注入和传输层方面,通过使用更加优化的HIL等来提高空穴注入和传输几率;在QD发光层方面,用短链配体来置换量子点的长链配体以增加载流子向量子点发光层中的传输效率等。在进行量子点配体交换的同时带来了量子点在正交溶剂中的可溶性优势,有利于QLED器件的全溶液法制备。

关键词：量子点发光二极管电子阻挡层空穴注入层电荷平衡

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Glucose transporters expression in the placental terminal villi of preeclampsia and intrauterine growth retardation complicated pregnancies

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Health 2013年第7期5卷 100-104页

作者： Elena A. Dubova Konstantin A. pavlov Galina V. Kulikova Alexander I. Shchegolev Gennady T. Sukhikh Department of Pathology Research Center for Obstetrics Gynecology and Perinatology Moscow Russia

Introduction: Transmembrane sodium-independent glucose transporters (GLUTs) play an important role in both placental and fetal development by the providing transplacental glucose transport. Abnormal GLUT-1 and GLUT-3 placental expression could play a role in such late pregnancy complications development as preeclampsia and intrauterine growth retardation. Materials and Methods: Immunohistochemistry was performed to reveal patterns of GLUT-1 and GLUT-3 expression in the placental terminal villi compartments. Results: GLUT-1 syncytial expression in the terminal villi of severe PE cases (both with and without IUGR) was significantly lower in compare to control group. We also report about GLUT-3 both syncytial and endothelial expression in the near term and term placental terminal villi without significant difference between the study and control groups. Conclusion: other study should be performed to establish the nature of GLUT-1 downregulation in severe preeclampsia cases and whether GLUT-3 is expressed in the syncytiotrophoblast of near term and term placentas or not.

关键词： Preeclampsia Placenta GLUT-1 GLUT-3

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自动化制造系统中产品制造过程的数学模拟

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机床与液压 2007年第6期35卷 71-73,86页

作者：张永春 В.В.Павлов 大连水产学院大连116300 莫斯科国立工业大学斯坦金莫斯科101472

为适应当前对制造系统的自动化、精密化、柔性化程度越来越高的要求,实现产品设计制造方案最优化,缩短产品的开发周期,本文运用数学的理论和方法,基于理论集合、数理逻辑和图论水平创建了机械产品制造过程的数学模型,并模拟其制造过程。

关键词：数学模拟自动化制造系统制造过程模型

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在TSV应用中控制电镀槽

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集成电路应用 2008年第5期25卷 40-42,48页

作者： Michael pavlov Eugene Shalyt Peter Bratin ECI Technology

与无添加试剂技术相结合,CVS分析可以保证电镀槽中的无机组分处于适当浓度,而这对于具有量产价值的穿透硅通孔(TSV)工艺来说非常重要。

关键词：应用电镀槽 TSV 半导体制造商控制封装尺寸晶圆级封装电化学沉积

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Assessment of Mercury in Diagnostic Biomaterials of Different Population Groups in Urban Areas of the Moscow Region

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Advances in Microbiology 2019年第7期9卷 571-580页

作者： Anatoly V. Gorbunov Sergey M. Lyapunov Irina N. Ilchenko Marina V. Frontasyeva Sergey S. pavlov Geological Institute of Russian Academy of Sciences Moscow Russian I. M. Sechenov First Moscow State Medical University (Sechenov University) Moscow Russian Frank Laboratory of Neutron Physics Joint Institute for Nuclear Research Dubna Russian

The results of a survey of different population groups in urban areas of the Moscow Region (industry workers, residents of areas with increased anthropogenic load of mercury and conditionally pristine areas, cohorts of pregnant women and children) to assess the contents of mercury in samples of various diagnostic biomaterials taken during the course of research are presented. Mercury concentrations in venous and umbilical cord blood, urine, hair, and nails were determined by means of instrumental neutron activation analysis and cold vapor atomic absorption spectrometry. Peculiarities of selection, transportation, storage, and preparation for analysis of samples of hair, nails, urine and umbilical venous blood are described. The determined concentrations of mercury in the studied diagnostic biomaterials are compared with normal and thresholds values. Although increased mercury concentrations were observed in some cases, no significant exposure of mercury was evident in general in the study towns. A positive correlation between the degree of consumption of seafood during pregnancy and a high content of mercury in the analyzed diagnostic biomaterials was shown.

关键词： Mercury Hair Nails Urine Venous and Umbilical Cord Blood The Impact The Human

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零部件制造商加工制造能力考核评价方法的研究

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机械设计与制造 2006年第2期 122-124页

作者：张海燕 V.V.pavlov 李宗斌姜莉莉刘作毅广东工业大学广州510090 国立莫斯科工业大学西安交通大学西安710000

在全球经济一体化的环境下,复杂产品的制造是由多个制造商共同完成。为考核不同制造商零部件的加工能力,需要对制造商的加工能力进行分析。在简单叙述多色集合和多色图的基础上,运用多色集合理论及多色图,建立了产品加工系统的数学模型... 详细信息

在全球经济一体化的环境下,复杂产品的制造是由多个制造商共同完成。为考核不同制造商零部件的加工能力,需要对制造商的加工能力进行分析。在简单叙述多色集合和多色图的基础上,运用多色集合理论及多色图,建立了产品加工系统的数学模型,然后根据多色集合的析取和合取形式,对制造商的加工能力给出了分析预测的数学公式和方法。用案例说明了应用上述理论的步骤和方法。

关键词：零部件制造能力评价考核仿真

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Mass Rock Fall Prediction in Zhezkazgan Mines at the Basis of Seismic Regime Analyzing.

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CT理论与应用研究（中英文） 2000年第Z1期9卷 91-94页

作者： Tomilin N.G Kuksenko V.S pavlov P.I Setov M.Zh Mansurov V.A A.F. Ioffe Physic o-Tekhnical Institute Russian Academy of Sciences Siberian Aerospace Academy Khazahmis corporation

Zhezkazgan copper deposit is strongly exploited since 1942. Its typical feature is multilevel mineralization. Mine′s thickness of sedimentary rock. Primary copper supply is from 150 to 450meters in depth. Capacity of ore body is 1,5～30 m; suddenly 30 - 60 meters. High capacity parts of deposit is mined oUt by room -pillar system. Stress state of rock mass of the deposit is characterized by that, what horizontal stresses is higher in 4～ 10 times than vertical stresses, which is caused by weight of straining thickness of sedimentary rock and submeridianally oriented. At present over than 50 thousands of pillars is formed as the result of deposit mining. Mined oUt area is divided on separate parts by over than 400 barrier and chain pillars. Spread of primary traderground tunnels exceeds 1200 kilometers, 540kilometers of the spread is operating mines. Tens of any purposes shafts are exploited with general spread of 45 kilometers. Some its decreasing at last time is caused by filling of emptiness by loosened rock as the result of happening falls at mines (Fig. 1).

关键词： Mass Rock Fall Prediction in Zhezkazgan Mines at the Basis of Seismic Regime Analyzing rock

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