检索结果-南通市图书馆

In vivo astrocyte reprogramming following spinal cord injury

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

neural Regeneration Research 2024年第3期19卷 487-488页

作者： Yannick n.Gerber Florence e.Perrin MMDn University of MontpellierEPHEINSERMMontpellierFrance Institut Universitaire de France(IUF) ParisFrance

Harmful and helpful roles of astrocytes in spinal cord injury(SCI):SCI induce gradable sensory,motor and autonomic impairments that correlate with the lesion severity and the rostro-caudal location of the injury *** absence of spontaneous axonal regeneration after injury results from neuron-intrinsic and neuron-extrinsic ***,not only adult neurons display limited capability to regrow axons but also the injury environment contains inhibitors to axonal regeneration and a lack of growth-promoting *** other cell populations that respond to the lesion,reactive astrocytes were first considered as only detrimental to spontaneous axonal ***,astrocytes.

关键词： injury impairment programming

nanomotion of bacteria to determine metabolic profile

在线全文

学校读者我要写书评

暂无评论

nanotechnology and Precision engineering 2024年第1期7卷 1-9页

作者： S.n.Pleskova e.V.Lazarenko n.A.Bezrukov R.n.Kriukov A.V.Boryakov M.e.Dokukin S.I.Surodin Research Laboratory of Scanning Probe Microscopy Lobachevsky State University of Nizhny NovgorodNizhny Novgorod 603950Russia Department of nanotechnology and Biotechnology Nizhny Novgorod State Technical University n.a.R.E.AlekseevNizhny Novgorod 603950Russia Sarov Physics and Technology Institute National Research Nuclear University MEPhISarov 607186Russia

In addition to their visible motion such as swimming(e.g.,with the help ofﬂagella),bacteria can also exhibit nanomotion that is detectable only with highly sensitive instruments,and this study shows that it is possible to detect bacterial nanomotion using an AFM detection *** results show that the nanomotion characteristics depend on the bacterial strain,and that nanomotion can be used to sense the metabolic activity of bacteria because the oscillations are sensitive to the food preferences of the bacteria and the type of surrounding medium.

关键词： nanomotion Bacteria Cantilever Oscillation Atomic force microscopy Metabolism

Landau quantization effects on damping Kawahara solitons in electron–positron–ion plasma in rotating ionized medium

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2024年第10期76卷 143-152页

作者： e I el-Awady S Hussain n Akhtar Department of Physics Faculty of Science Port Said University Theoretical Physics Division (TPD) PINSTECH

For the dynamics of three-dimensional electron–positron–ion plasmas, a fluid quantum hydrodynamic model is proposed by considering Landau quantization effects in dense ***–neutral collisions in the presence of the Coriolis force are also considered. The application of the reductive perturbation technique produces a wave evolution equation represented by a damped Korteweg–de Vries equation. This equation, however, is insufficient for describing waves in our system at very low dispersion coefficients. As a result, we considered the highest-order perturbation, which resulted in the damped Kawahara equation. The effects of the magnetic field, Landau quantization, the ratio of positron density to electron density, the ratio of positron density to ion density, and the direction cosine on linear dispersion laws as well as soliton and conoidal solutions of the damped Kawahara equation are explored. The understanding from this research can contribute to the broader field of astrophysics and aid in the interpretation of observational data from white dwarfs.

关键词： Coriolis force Kawahara equation Landau quantization magnetoplasmas quantum plasma solitary and cnoidal waves

Transition from oceanic subduction to continental collision:Insights from volcanogenic-sedimentary rocks of the Tannuola terrane(northern Central Asian Orogenic Belt)

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Geoscience Frontiers 2024年第4期15卷 41-60页

作者： e.V.Vetrov n.I.Vetrova V.S.Sobolev Institute of Geology and Mineralogy SB RAS Koptyuga ave.3NovosibirskRussia

Magmatism associated with oceanic subduction plays a dominant role in crustal growth during the earth's *** Tannuola terrane,situated in the northern Central Asian Orogenic Belt(CAOB),is a key area to understanding oceanic subduction and initial collision processes in the northern *** order to investigate the switch from subduction to collision settings,detailed field mapping,zircon SHRIMP U-Pb geochronological and whole-rock geochemical studies of volcanogenic-sedimentary rocks from the Tannuola terrane were carried *** U-Pb ages indicate multi-stage volcanism lasted at least 30 Ma from~540 to~510 Ma,that can be divided into three events:the late ediacaran(before~540 Ma),the early Cambrian(~520 Ma)and the middle Cambrian(~510 Ma).These ages are inter-preted to the initial,main and final stages of oceanic subduction during the late Proterozoic-early *** the late ediacaran,tholeiitic basalts with highεnd(t)val.e.(from+7.4 to+8.5)were *** forming by the 10%-30%partial melting of spinel-garnet mantle source during slab *** the early Cambrian,transitional from tholeiitic to calc-alkaline basaltic rocks withεnd(t)val.e.+5.6)and coeval intermediate-felsic volcanic rocks with similarεnd(t)val.e.(+5.9 and+6.5)*** early Cambrian basaltic rocks are interpreted to be derived by 10%-30%partial melt-ing of a depleted mantle source metasomatized by slab-derived fluids released from the subducting ocea-nic *** middle Cambrian calcalkaline basaltic rocks withεnd(t)val.e.of+6.2 might be emplaced as a result of low(5%-10%)degree partial melting of a metasomatized mantle followed by fractional crys-tallization of clinopyroxene and *** intermediate-felsic volcanic rocks withεnd(t)val.e. from+6.0 to+6.8 were formed through fractionation of the juvenile neoproterozoic *** middle Cambrian volcanism is interpreted to be triggered by the slab break-off during the transition to a collisional se

关键词： Island-arc magmatism ediacaran Cambrian zircon U-Pb dating nd isotopes Central asian orogenic belt

new trends in diagnosis and management of gallbladder carcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第1期16卷 13-29页

作者： efstathios T Pavlidis Ioannis n Galanis Theodoros e Pavlidis ^(nd)Propedeutic Department of Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladder(GB)carcinoma,although relatively rare,is the most common biliary tree cholangiocarcinoma with aggressiveness and poor *** is closely associated with cholelithiasis and long-standing large(>3 cm)gallstones in up to 90%of *** other main predisposing factors for GB carcinoma include molecular factors such as mutated genes,GB wall calcification(porcelain)or mainly mucosal microcalcifications,and GB polyps≥1 cm in *** is made by ultrasound,computed tomography(CT),and,more precisely,magnetic resonance imaging(MRI).Preoperative staging is of great importance in decisionmaking regarding therapeutic *** staging is based on MRI findings,the leading technique for liver metastasis imaging,enhanced three-phase CT angiography,or magnetic resonance angiography for major vessel *** is also necessary to use positron emission tomography(PeT)-CT or ^(18)F-FDG PeT-MRI to more accurately detect metastases and any other occult deposits with active metabolic *** laparoscopy may detect dissemination not otherwise found in 20%-28.6%of *** treatment is needed,including surgical resection,targeted therapy by biological agents according to molecular testing gene mapping,chemotherapy,radiation therapy,and *** is of great importance to understand the updated guidelines and current treatment *** extent of surgical intervention depends on the disease stage,ranging from simple cholecystectomy(T1a)to extended resections and including extended cholecystectomy(T1b),with wide lymph node resection in every case or IV-V segmentectomy(T2),hepatic trisegmentectomy or major hepatectomy accompanied by hepaticojejunostomy Roux-Y,and adjacent organ resection if necessary(T3).Laparoscopic or robotic surgery shows fewer postoperative complications and equivalent oncological outcomes when compared to open surgery,but much attention must be paid to avoiding *** addition to surgery,novel targe

关键词： Biliary tract neoplasms extrahepatic cholangiocarcinoma Gallbladder carcinoma Gallbladder diseases Biliary tree diseases Gastrointestinal malignancies

RBC aggregation,deformation and adhesion to endothelium:Role of nitric oxide derived from L-Arginine and sodium nitroprusside

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Innovative Optical Health Sciences 2024年第5期17卷 53-65页

作者： M.K.Maksimov P.B.ermolinskiy O.n.Scheglovitova n.n.Sklyankina A.V.Muravyov A.e.Lugovtsov A.V.Priezzhev Faculty of Physics M.V.Lomonosov Moscow State University bld.1subbuilding.2Leninskie goryMoscow 11991Russia n.F.Gamaleya national Research Center for epidemiology and Microbiology 18 Gamaleya StreetMoscow 123098Russia K.D.Ushinsky Yaroslavl State Pedagogical University 108/1 Respublikanskaya StreetYaroslavl 150000Russia

Red blood cells(RBCs)are the most abundant human blood *** aggregation and deformation strongly determine blood viscosity which impacts hemorheology and *** turn,RBC properties depend on di®erent endogenous and exogenous *** such factor is nitric oxide(nO),which is mainly produced by endothelial cells(eC)from L-arginine amino acid in the circulatory *** the mechanisms of the RBC-endothelium interplay are not clear up to date and considering its possible clinical importance,the aims of this study are to investigate in vitro:(1)The e®ect of L-arginine induced nO on RBC aggregation and adhesion to endothelium;(2)the nO e®ect on RBC aggregation and deformation induced by L-arginine and sodium nitroprusside without the presence of endothelium in the *** RBC aggregation and adhesion to a monolayer of eC were studied using optical tweezers(OT).The RBC deformability and aggregation without endothelium in the samples were studied using the°ow chamber method and Myrenne *** con¯rmed that nO increases deformability and decreases aggregation of *** showed that the soluble guanylate cyclase pathway appears to be the only nO signaling pathway *** the samples with the endothelium,the\bell-shaped"dependence of RBC aggregation force on L-arginine concentration was observed,which improves our knowledge about the process of nO production by ***,data related to L-arginine accumulation by endothelium were obtained:necessity of the presence of extracellular L-arginine stated by other authors was put under *** our study,nO decreased the RBC-endothelium adhesion,however,the tendency appeared to be weak and was not con¯rmed in another set of *** our knowledge,this is the¯rst attempt to measure the forces of RBC adhesion to endothelium monolayer with OT.

关键词： Red blood cells aggregation L-arginine endothelium optical tweezers Myrenne flow chamber

Management of obstructed colorectal carcinoma in an emergency setting:An update

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第3期16卷 598-613页

作者： efstathios T Pavlidis Ioannis n Galanis Theodoros e Pavlidis 2nd Propedeutic Department of Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Colorectal carcinoma is common,particularly on the left *** 20%of patients,obstruction and ileus may be the first clinical manifestations of a carcinoma that has advanced(stage II,III or even IV).Diagnosis is based on clinical presentation,plain abdominal radiogram,computed tomography(CT),CT colonography and positron emission tomography/*** best management strategy in terms of short-term operative or interventional and long-term oncological outcomes re-mains *** the most common left-sided obstruction,the first choice should be either emergency surgery or endoscopic decompression by self-expen-dable metal stents or *** operative plan should be either one-stage or two-stage ***-stage resection with on-table bowel decompression and irrigation can be accompanied or not accompanied by proximal defunctioning stoma(colostomy or ileostomy).Primary anastomosis is more convenient but has increased risks of anastomotic leakage and ***-stage resection(Hart-mann’s procedure)is safer and the most widely used despite temporally affecting quality of *** control surgery in high-risk frail patients is less frequently performed since it can be successfully substituted with endoscopic stenting or *** the less common right-sided obstruction,one-stage surgical resection is more beneficial than endoscopic *** role of minimally invasive surgery(laparoscopic or robotic)is a subject of *** laparoscopic-assisted management is advantageous to some extent but requires much expertise due to inherent difficulties in dissecting the distended colon and the risk of rup-ture and subsequent septic *** decompressing stent as a bridge to elective surgery more substantially decreases the risks of morbidity and mortality than emergency surgery for decompression and has equivalent medium-term overall survival and disease-free survival *** combination with neoadjuvant chemotherapy or radiation may have a p

关键词： Acute abdomen Obstructive ileus Colorectal carcinoma emergency surgery Colectomy Intraluminal metal stents

effect of different drying methods on the amino acids,α-dicarbonyls and volatile compounds of rape bee pollen

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年第1期13卷 517-527页

作者： Yanxiang Bi Jiabao ni Xiaofeng Xue Zidan Zhou Wenli Tian valérie Orsat Sha Yan Wenjun Peng Xiaoming Fang State Key Laboratory of Resource Insects Institute of Apicultural ResearchChinese Academy of Agricultural SciencesBeijing 100093China College of engineering China Agricultural UniversityBeijing 100083China Bioresource engineering Dept. McGill UniversitySte-Anne-de-Bellevue QC H9X 3V9Canada

The significant demand for high quality food has motivated us to adopt appropriate processing methods to improve the food nutritional quality and *** this study,the effects of five drying methods,namely,pulsed vacuum drying(PVD),freeze drying(FD),infrared drying(IRD),hot-air drying(HAD)and sun drying(SD)on free amino acids(FAAs),α-dicarbonyl compounds(α-DCs)and volatile compounds(VOCs)in rape bee pollen(RBP)were *** results showed that FD significantly released the essential amino acids(eAAs)compared with fresh samples while SD caused the highest *** was the dominantα-DCs in RBP and the highest loss was observed after *** were the dominant volatiles of RBP and SD samples contained more new volatile substances(especially aldehydes)than the other four drying ***,FD and PVD would be potential methods to effectively reduce the quality deterioration of RBP in the drying process.

关键词： Drying Bee pollen Free amino acids α-Dicarbonyl compounds Volatile compounds

First results of turbulence investigation on Globus-M2 using radial correlation Doppler reflectometry

在线全文

学校读者我要写书评

暂无评论

Plasma Science and Technology 2024年第10期26卷 49-55页

作者： A.POnOMARenKO A.YASHIn V.GUSeV e.KISeLeV G.KURSKIeV V.MInAeV Y.PeTROV n.SAKHAROV P.SHCHeGOLeV e.TKACHenKO n.ZHILTSOV Peter the Great St.Petersburg Polytechnic University St.Petersburg 195251Russia Ioffe Institute St.Petersburg 194064Russia

The first results of investigation of the turbulence structure using Doppler backscattering(DBS)on the Globus-M2 tokamak are presented.A one-channel DBS system with a variable probing frequency within the 18–26 GHz range was installed to investigate the edge plasma at normalized minor radiiρ=0.9–*** correlation Doppler reflectometry was used to study the changes in turbulence eddies after the LH *** analysis was applied to the phase derivative of complex in-phase and quadrature(IQ)signals of the DBS diagnostic as it contains information about the poloidal plasma rotation *** L-mode,the radial correlation length L_(r)is estimated to be 3 cm and after transition to H-mode reduces to approximately 2 *** modelling in a linear local approximation using code Gene indicates that the instability with positive growth rate at the normalized minor radiusρ=0.75 in L-mode and H-mode on Globus-M2 was the ion temperature gradient(ITG)mode.

关键词： tokamak turbulence Doppler backscattering correlation reflectometry