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Isolated intramedullary tuberculoma of the dorsal cord:a rare clinico-radiological entity

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Asian Pacific Journal of Tropical Medicine 2010年第12期3卷 1004-1005页

作者： Sumeet Bhargava Rajul rastogi Gaurav Jindal Amrit Kumar Singh vaibhav rastogi Yash Diagnostic Center Yash Hospital and Research CenterCivil LinesKanth RoadMoradabad(UP)-244001India Neuron Advanced Neurosurgery CenterMoradabodUPIndia Yash Diagnostic Center Yash Hospital and Research CenterCivil LinesKanth RoadMoradabad(UP) -244001India

Tuberculous infection manifesting as an isolated intramedullary tuberculoma of the spinal cord is distinctly *** report a case of a 35 year old woman presenting with an insidious onset of myelopathy,where MRI showed c... 详细信息

关键词： Intramedullary tuberculoma MRI Dorsal cord

Orbital apex syndrome secondary to myocysticercosis: a rare case report

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International Journal of Ophthalmology(English edition) 2020年第6期13卷 1013-1014页

作者： Shweta Dhiman Kamlesh AnAND Anju rastogi Paromita Dutta Parul Jain Manisha Mishra vaibhav Nagpal Department of Ophthalmology Guru Nanak Eye CentreMaulana Azad Medical CollegeNew Delhi 110002India

Dear Editor,We present a rare case report of orbital apex syndrome secondary to *** cysticercosis is caused by larval form(Cysticercus cellulosae)of Taenia *** cysts of Cysticercus cellulosae can lodge in the centralnervoussystem,muscles,subcutaneoustissue,or eye,resulting in varied clinical manifestations[1].This case highlights an unusual presentation of orbital apex syndrome secondary to cysticercosis of medial rectus.

关键词： MRI a rare case report Orbital apex syndrome secondary to myocysticercosis

Changing role of histopathology in the diagnosis and management of hepatocellular carcinoma

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World Journal of Gastroenterology 2018年第35期24卷 4000-4013页

作者： Archana rastogi Department of Pathology Institute of Liver & Biliary SciencesNew Delhi 110070 India

Hepatocellular carcinoma (HCC) is one of the most common and fatal cancer in the world. HCC frequently presents with advanced disease, has a high recurrence rate and limited treatment options, which leads to very poor prognosis. This warrants urgent improvement in the diagnosis and treatment. Liver biopsy plays very important role in the diagnosis and prognosis of HCC, but with technical advancements and progression in the field of imaging, clinical guidelines have restricted the role of biopsy to very limited situations. Biopsy also has its own problems of needle tract seeding of tumor, small risk of complications, technical and sampling errors along with interpretative errors. Despite this, tissue analysis is often required because imaging is not always specific, limited expertise and lack of advanced imaging in many centers and limitations of imaging in the diagnosis of small, mixed and other variant forms of HCC. In addition, biopsy confirmation is often required for clinical trials of new drugs and targeted therapies. Tissue biomarkers along with certain morphological features, phenotypes and immune-phenotypes that serve as important prognostic and outcome predictors and as decisive factors for therapy decisions, add to the continuing role of histopathology. Advancements in cancer biology and development of molecular classification of HCC with clinic pathological correlation, lead to discovery of HCC phenotypic surrogates of prognostic and therapeutically significant molecular signatures. Thus tissue characteristics and morphology based correlates of molecular subtypes provide invaluable information for management and prognosis. This review thus focuses on the importance of histopathology and resurgence of role of biopsy in the diagnosis, management and prognostication of HCC.

关键词： Hepatocellular carcinoma Biomarker Biopsy Histopathology Immunohistochemistry Targeted therapy Molecular Diagnosis Prognosis

Weaning of nasal CPAP in preterm infants:who,when and how?a systematic review of the literature

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World Journal of Pediatrics 2015年第1期11卷 7-13页

作者： Shaili Amatya Deepa rastogi Alok Bhutada Shantanu rastogi Division of Neonatology Maimonides Infants&Children's Hospital4802 Tenth AveK-113Brooklyn NY 11219USA Children's Hospital at Montefiore Albert Einstein College of MedicineBronxNY 10467USA

Background:There is increased use of early nasal continuous positive airway pressure(NCPAP)to manage respiratory distress in preterm infants but optimal methods and factors associated with successful wean are not well defined.A systematic review was performed to define the corected gestational age(CGA),weight to wean NCPAP and the methods associated with successful weaning of the NCPAP among preterm infants,along with factors affecting ***:Searches were made of PubMed using the keywords-NCPAP,CPAP,weaning,withdrawal,preterm,and infants from its inception to January 1st,2014,for studies in all languages but limited to *** reviews(including cross references)were also *** included all randomized and quasi-randomized controlled trials where preterm neonates were randomized to different NCPAP weaning *** of CGA,weight and methods used for weaning NCPAP were extracted along with factors which affect its ***:Seven studies met the search *** successful wean was at 32 to 33 weeks CGA and at 1600 *** different methods were used for weaning were sudden,gradual pressure wean and gradual graded time off *** for readiness,success and failure to wean were *** affecting successful weaning were intubation,anemia,infection and gastro-esophageal ***:The successful wean was at 32 to 33 weeks CGA and 1600 *** for readiness,success and failure to wean are well *** weaning may be associated with a shorter weaning *** trials are needed comparing weaning methods using defined criteria for readiness and success of NCPAP wean and stratify the results by gestational age and birth weight.

关键词： continuous positive airway pressure infants preterm systematic review weaning

Pathomolecular characterization of HCC in non-cirrhotic livers

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Hepatoma Research 2020年第8期6卷 12-28页

作者： Archana rastogi Department of Pathology Institute of Liver&Biliary SciencesNew Delhi-110070India.

Hepatocellular carcinoma(HCC)is the most common primary liver cancer and usually arises in cirrhotic ***,it is diagnosed in non-cirrhotic livers.A variety of risk factors and etiologies can trigger the development of HCC in non-fibrotic and non-cirrhotic *** most important causes are metabolic syndrome and hepatitis B virus *** pathogenetic mechanisms are direct carcinogenesis,chronic liver injury and repair cycles,and genetic/epigenetic *** has a very important role in the diagnosis of non-cirrhotic *** features of non-cirrhotic HCC are quite different from HCC originating in a cirrhotic *** characteristics are similar to a classical ***,certain histological variants show a predilection to occur in non-cirrhotic *** encompass fibrolamellar,scirrhous,steatohepatitic and mixed hepato-cholangiocarcinoma *** to the non-cirrhotic background,adenoma,metastasis and most of the other non-neoplastic and neoplastic conditions enter the differential *** studies and morpho-molecular classifications of HCC provide further understanding of the molecular pathogenesis of non-cirrhotic *** group however,has rarely been exclusively *** review offers an update of etiology,patho-molecular characteristics and differential diagnosis of HCC arising in non-cirrhotic backgrounds.

关键词： Hepatocellular carcinoma non-cirrhotic etiopathogenesis molecular genetics pathology patho-molecular differential diagnosis

Food resource and temporal partitioning amongst a guild of predatory agroecosystem-inhabiting ant species

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Current Zoology 2009年第5期55卷 366-375页

作者： Vivek Mohan AGARWAL Neelkamal rastogi Center of Advanced Study in Zoology Banaras Hindu University

Prey diversity and temporal foraging patterns of six abundant,predatory ant species were investigated seasonally in an agroecosystem with two main vegetable *** *** the highest predation success and therefore appears to be the dominant species while Tapinoma melanocephalum showed the lowest success under the natural field *** of prey diversity and temporal activity patterns with the null model tests of niche overlap revealed a significant overlap indicating that the activity periods and prey diversity may not be solely influenced by interactions among the co-existing ant ***,niche partitioning in the daily peak activity periods was demonstrated during all the three seasons(summer,rainy and winter)particularly between Pheidole *** *** *** a high intensity,broadly extended mono-modal foraging *** compressus and *** showed bi-modality in their foraging activity during the rainy season and mono-modal patterns during summer and winter *** tesserinoda,Tetramorium *** *** exhibited peak foraging activities in the morning hours during the summer and rainy *** activity profiles of *** and *** were skewed towards late afternoon hours during the winter season indicating avoidance of foraging activity during the favourable periods when the more aggressive Pheidole *** *** the sponge gourd agroecosystem,the ants captured predominantly hymenopteran,orthopteran and coleopteran *** Pheidole *** mainly the large orthopteran prey,other ant species captured worker ants in the sponge gourd *** the cauliflower agroecosystem,while other species captured prey chiefly belonging to six orders,i.e.,Lepidoptera,Hymenoptera,Coleoptera,Hemiptera,Isoptera and Diptera,Pheidole *** *** were the only species to also hunt many orthopteran *** agroecosystem-inhabiting ant speci

关键词： Niche partitioning Temporal niche Prey diversity Annual cropping system

Tuning thermal release kinetics of soy oil from organic nanoparticles using variable synthesis conditions

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Particuology 2016年第3期14卷 54-65页

作者： Pieter Samyn Dieter Van Nieuwkerke Vibhore rastogi Dirk Stanssens University of Freiburg Freiburg Research Institute for Advances Studies (FRIAS) Faculty for Environment and Natural Resources Chair of Bio-based Materials Engineering Werthmannstrasse 6 D-79085 Freiburg Germany Ghent University Department of Textiles Technologiepark 907 B-9052 Zwijnaarde Belgium Topehim N.K Nijverheidsstraat 98 B-2160 Wommelgem Belgium

The thermal release properties of soy oil from poly（styrene-co-maleimide） nanoparticles containing 50 wt% encapsulated oil have been quantified as a function of temperature and time. The effects of dif- ferent synthesis conditions on the thermal stability of the nanoparticles and their oil release have been evaluated, i.e., by gradually increasing the amount of ammonium hydroxide used for the imidization of poly（styrene-co-maleic anhydride）. First, the intrinsic thermal properties of the oil-filled nanoparti- cles were analysed by differential scanning calorimetry, which revealed an exothermal reaction related to the oil release and a suppression of the glass transition that may be masked owing to the complex structure of the hybrid nanoparticles. The isothermal scans showed different rates of oil release after a post-imidization reaction. The oil release was better followed by dynamic mechanical analysis, which illustrated changes in visco-elastic properties expressed by the maximum in the loss factor that related to the amount of released oil. Depending on the amount of ammonium hydroxide, the oil started to release below the glass transition temperature at various rates. Thermal release profiles of the oil we re quantified by infrared and Raman spectrocopy after heating for 2 min to 6 h at 125 to 250 ℃, based on variations in oil-related and imide-related absorption bands. The oil release increased below and above the glass transition temperature, following a parabolic trend, and progressively decreased at higher ammonium hydroxide concentrations, in parallel with higher imide content and changes in imide conformation. The kinetics and mechanism of the oil release can be described by the Korsmeyer-Peppas model, suggesting a dominating diffusion mechanism that is influenced by further imidization of the polymer matrix during heating.

关键词： Soy oil Nanoparticle Encapsulation Release

Novel design techniques for noise-tolerant power-gated CMOS circuits

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Journal of Semiconductors 2017年第1期38卷 106-112页

作者： Rumi rastogi Sujata Pandey Department of Electronics and Communication Engineering Amity University Uttar PradeshNoidaIndia

In this paper we have investigated the single phase sleep signal modulation technique,step-wise V_（gs）technique and the three-phase reactivation technique to evaluate the noise characteristics of multi-threshold CMOS circuits used in communication *** stacking technique is also implemented in this paper for the sleep *** stacking approach helps to minimize leakage *** mode transition noise minimization techniques have been applied to 32-bit dynamic TSPC adder with stacked sleep transistors in a standard 45-nm CMOS *** reactivation noise,delay and energy consumption of all the three techniques have been *** has been shown that the three phase modulation technique significantly minimizes the reactivation delay when the peak noise level is maintained the same for all three *** three phase modulation technique shows 67.3%and 35%reduction in delay compared to the single phase and step-wise Vgs modulation techniques *** reactivation energy is also suppressed by 49.3%and 39.14%with respect to the single-phase and stepwise Vgs techniques.

关键词： MTCMOS noise tolerant low power

Nicotinamide adenine dinucleotide phosphate oxidase activation and neuronal death after ischemic stroke

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Neural Regeneration Research 2019年第6期14卷 948-953页

作者： Jiamei Shen Radhika rastogi Xiaokun Geng Yuchuan Ding China-America Institute of Neuroscience Beijing Luhe HospitalCapital Medical University Department of Neurosurgery Wayne State University School of Medicine Department of Neurology Beijing Luhe HospitalCapital Medical University

Nicotinamide adenine dinucleotide phosphate oxidase(NOX) is a multisubunit enzyme complex that utilizes nicotinamide adenine dinucleotide phosphate to produce superoxide anions and other reactive oxygen species. Under normal circumstances, reactive oxygen species mediate a number of important cellular functions, including the facilitation of adaptive immunity. In pathogenic circumstances, however,excess reactive oxygen species generated by NOX promotes apoptotic cell death. In ischemic stroke, in particular, it has been shown that both NOX activation and derangements in glucose metabolism result in increased apoptosis. Moreover, recent studies have established that glucose, as a NOX substrate, plays a vital role in the pathogenesis of reperfusion injury. Thus, NOX inhibition has the potential to mitigate the deleterious impact of hyperglycemia on stroke. In this paper, we provide an overview of this research,coupled with a discussion of its implications for the development of NOX inhibition as a strategy for the treatment of ischemic stroke. Both inhibition using apocynin, as well as the prospect of developing more specific inhibitors based on what is now understood of the biology of NOX assembly and activation, will be highlighted in the course of our discussion.

关键词： nicotinamide adenine dinucleotide phosphate oxidase stroke nicotinamide adenine dinucleotide phosphate oxidase inhibitors reactive oxygen species ischemia/reperfusion neuroprotection hyperglycolysis NADPH NOX