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Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging

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Light(Science & Applications) 2019年第1期8卷 1108-1116页

作者： James A.Winkelmann Aya Eid Graham Spicer Luay m.Almassalha The-Quyen Nguyen vadim Backman Department of Biomedical Engineering Northwestern UniversityEvanstonIL 60208USA Department of Chemical and Biological Engineering Northwestern UniversityEvanstonIL 60208USA

Optical coherence tomography angiography relies on motion for contrast and requires at least two data acquisitions per pointwise scanning *** present a method termed spectral contrast optical coherence tomography angiography using visible light that relies on the spectral signatures of blood for angiography from a single scan using endogenous *** demonstrate the molecular sensitivity of this method,which enables lymphatic vessel,blood,and tissue discrimination.

关键词： enable signature spectral

The Berezitovoe gold-polymetallic deposit(Upper Amur region,Russia)：Structure,mineralogy and genetic aspects

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Geoscience Frontiers 2016年第3期7卷 483-494页

作者： Alexandr S. Vakh vadim G. Khomich Natalia G. Boriskina m. Santosh far East Geological Institute Far East Branch of Russian Academy of Sciences 159 Prospect 100 let Vladivastoku Vladivostok 690022 Russia School of Engineering Far Eastern Federal University 8 Suhanova St. Vladivostok 690950 Russia Department of Earth Sciences University of Adelaide SA 5005 Australia School of Earth Sciences and Resources China University of Geosciences Beijing 29 Xueyuan Road Beijing 100083 China

The Berezitovoe deposit in the Sergachi volcano-plutonic and metallogenic belt preserves evidence for polymetallic mineralization of multiple *** steeply dipping gamet-tourmaline-muscovite-quartz metasomatites（with K-Ar ages of 132 ± 2.9 and 127 ± 4.4 ma） carry two distinct stages of mineralization developed at different times：（1） polymetallic mineralization and（2） *** deposit is located within Paleozoic gneissose granitoids of the Pikansky complex（dated as 379 ± 1.1 ma by zircon U-Pb method） intruded by early Cretaceous porphyry-like granites of the Haikta pluton（dated as137 ± 0.67 ma by zircon U-Pb method） and late Cretaceous dikes of porphyrites,porphyries,and *** suggests the action of late gold-bearing hydrothermal fluids on the early polymetallic ores and the selective mobilization of some elements from these lead to redeposition together with complex sulphosalts.

关键词： Amur River head Gold Early Cretaceous metallogeny Tectonics

SPH-BEm simulation of underwater explosion and bubble dynamics near rigid wall

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Science China(Technological Sciences) 2019年第7期62卷 1082-1093页

作者： ZHANG ZhiFan WANG Cheng ZHANG A-man Silberschmidt vadim V WANG LongKan State Key Laboratory of Explosion Science and Technology Beijing Institute of Technology Beijing 100081 China College of Shipbuilding Engineering Harbin Engineering University Harbin 150001 China Wolfson School of mechanical Electrical and Manufacturing Engineering Loughborough University Leicestershire LE11 3TU UK China Ship Research and Development Academy Beijing 100101 China

A process of underwater explosion of a charge near a rigid wall includes three main stages: charge detonation, bubble pulsation and jet formation. A smoothed particle hydrodynamics(SPH) method has natural advantages in solving problems with large deformations and is suitable for simulation of processes of charge detonation and jet formation. On the other hand, a boundary element method(BEm) is highly efficient for modelling of the bubble pulsation process. In this paper, a hybrid algorithm, fully utilizing advantages of both SPH and BEm, was applied to simulate the entire process of free and near-field underwater explosions. First, a numerical model of the free-field underwater explosion was developed, and the entire explosion process–from the charge detonation to the jet formation–was analysed. Second, the obtained numerical results were compared with the original experimental data in order to verify the validity of the presented method. Third, a SPH model of underwater explosion for a column charge near a rigid wall was developed to simulate the detonation process. The results for propagation of a shock wave are in good accordance with the physical observations. After that, the SPH results were employed as initial conditions for the BEm to simulate the bubble pulsation. The obtained numerical results show that the bubble expanded at first and then shrunk due to a differences of pressure levels inside and outside it. Here, a good agreement between the numerical and experimental results for the shapes, the maximum radius and the movement of the bubble proved the effectiveness of the developed numerical model. Finally, the BEm results for a stage when an initial jet was formed were used as initial conditions for the SPH method to simulate the process of jet formation and its impact on the rigid wall. The numerical results agreed well with the experimental data, verifying the feasibility and suitability of the hybrid algorithm. Besides, the results show that, due to t

关键词： underwater explosion SPH-BEm algorithm load characteristics

Catalytic co-combustion of biomass and brown coal in a fluidized bed:Economic and environmental benefits

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Journal of Environmental Sciences 2024年第6期140卷 24-36页

作者： Yury V.Dubinin Nikolay A.Yazykov Petr m.Yeletsky Roman B.Tabakaev Aleksandra I.Belyanovskaya vadim A.Yakovlev Federal Research Center Boreskov Institute of Catalysis SB RAS Lavrentiev Ave.5Novosibirsk630090Russia University of Tyumen Volodarskogo str.6Tyumen625003Russia

The work is devoted to the study of combustion of brown coal,pine sawdust,and their mixtures in a fluidized bed of catalyst at 600-750℃.It is shown that an increase in the content of sawdust in a mixture with brown coal leads to an increase in the burnout degree of solid fuel from 94.4%to 99.9%,while the emission of greenhouse gases in the form of CO_(2)CO and NOxis reduced(CO_(2)from the biomass is not included in the balance).The high content of alkaline earth metal oxides(CaO and mgO)in the mineral part of brown coal,sawdust,and their mixtures eliminates the emission of sulfur oxides and the slagging of heat-exchange surfaces during the combustion in a fluidized bed of *** optimal temperature,when the highest burnout degree of the above fuels is achieved in the combustion is 750℃.It is also shown that the increase in temperature and the content of sawdust in the composition of the fuel mixtures has a positive effect on the economic and environmental process indicators.

关键词： Co-combustion Fluidized catalyst bed Biomass Coal Economic effect Environmental impact

Wide aperture piezoceramic deformable mirrors for aberration correction in high-power lasers

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High Power Laser Science and Engineering 2016年第1期4卷 22-28页

作者： vadim Samarkin Alexander Alexandrov Gilles Borsoni Takahisa Jitsuno Pavel Romanov Aleksei Rukosuev Alexis Kudryashov moscow State University of mechanical Engineering (mAmI) AKA Optics SAS Institute of Laser Engineering Osaka University

The deformable mirror with the size of 410 mmstacks was developed. The results ×468 mm controlled by the bimorph piezoceramic plates and multilayer piezoceramic of the measurements of the response functions of all the actuators and of the surface shape of the deformable mirror are presented in this paper. The study of the mirror with a Fizeau interferometer and a Shack–Hartmann wavefront sensor has shown that it was possible to improve the flatness of the surface down to a residual roughness of 0.033 μm(RmS). The possibility of correction of the aberrations in high-power lasers was numerically demonstrated.

关键词： deformable mirror high-power laser piezoelectric actuator wavefront sensor

Fluorine-containing drugs approved by the FDA in 2019

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Chinese Chemical Letters 2020年第9期31卷 2401-2413页

作者： Haibo mei Attila mario Remete Yupiao Zou Hiroki moriwaki Santos Fustero Lorand Kiss vadim ASoloshonok Jianlin Han Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources College of Chemical EngineeringNanjing Forestry UniversityNanjing 210037China University of Szeged Institute of Pharmaceutical Chemistry6720 SzegedEotvos u.6Hungary Hamari Chemicals Ltd. 1-4-29 KunijimaHigashi-Yodogawa-kuOsaka 533-0024Japan Departamento de Quimica Organica Universidad de Valencia46100 BurjassotValenciaSpain Department of Organic Chemistry 1 Faculty of ChemistryUniversity of the Basque Country UPV/EHUPaseo Manuel Lardizabal 320018 San SebastianSpain IKERBASQUE Basque Foundation for Science.Maria Diaz de Haro 3Plaza Bizkaia48013 BilbaoSpain

Eleven new fluorine-containing FDA-approved drugs have been profiled and details of their discovery and preparation are *** areas include schizophrenia,migraine,multiple sclerosis,insomnia,rheumatoid arthritis,anti-tuberculosis,breast cancer,lymphoma kinase inhibitor,serotonin receptor *** pharmaceuticals feature four examples of aromatic fluorine,three aromatic CF3 group,three aliphatic CF3 and one compound with aromatic CF3O ***,among the new compounds,six are chiral and seven are derived from tailor-made amino acids.

关键词： Fluorine Pharmaceuticals Synthesis medicinal chemistry marketed medicinal drugs

Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation

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Light(Science & Applications) 2015年第1期4卷 197-206页

作者： Ji Yi Wenzhong Liu Siyu Chen vadim Backman Nader Sheibani Christine m.Sorenson Amani A.Fawzi Robert A.Linsenmeier Hao F.Zhang Department of Biomedical Engineering Northwestern UniversityEvanstonIL 60208USA mcPherson Eye Research Institute University of WisconsinMadisonWI 53705USA Department of Ophthalmology Northwestern UniversityChicago Illinois 60611USA Department of Neurobiology Northwestern UniversityEvanstonIL 60208USA

The lack of capability to quantify oxygen metabolism noninvasively impedes both fundamental investigation and clinical diagnosis of a wide spectrum of diseases including all the major blinding diseases such as age-related macular degeneration,diabetic retinopathy,and *** visible light optical coherence tomography(vis-OCT),we demonstrated accurate and robust measurement of retinal oxygen metabolic rate(rmRO2)noninvasively in rat *** continuously monitored the regulatory response of oxygen consumption to a progressive hypoxic *** found that both oxygen delivery,and rmRO2 increased from the highly regulated retinal circulation(RC)under hypoxia,by 0.2860.08 μL min(^-1)(p,0.001),and 0.2060.04 μL min(^-1)(p,0.001)per 100 mmHg systemic pO2 reduction,*** increased oxygen extraction compensated for the deficient oxygen supply from the poorly regulated choroidal *** from an oxygen diffusion model based on previous oxygen electrode measurements corroborated our in vivo *** believe that vis-OCT has the potential to reveal the fundamental role of oxygen metabolism in various retinal diseases.

关键词： oxygen metabolism retinal circulation visible light optical coherence tomography

Effect of spring grass fires on vegetation patterns and soil quality in abandoned agricultural lands at local and landscape scales in Central European Russia

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Ecological Processes 2018年第1期7卷 448-466页

作者： Larisa G.Khanina vadim E.Smirnov michael S.Romanov maxim V.Bobrovsky Institute of mathematical Problems of Biology RAS branch of the M.V.Keldysh Institute of Applied Mathematics of the Russian Academy of Sciences1 Prof.Vitkevich StPushchinoMoscow Region 142290Russia Center for Forest Ecology and Productivity of the Russian Academy of Sciences 84/32 bldg.14 Profsoyuznaya StMoscow 117997Russia Institute of Physico-Chemical and Biological Problems in Soil Science of the Russian Academy of Sciences 2 Institutskaya StPushchinoMoscow Region 142290Russia

Introduction:Abandonment of agricultural land is often happening all over the world and widespread in *** lands are subject to successional changes in vegetation and it seems necessary to provide effective methods for a sustainable ecosystem management of those ***,factors which determine successional processes,especially fires,have not been studied in *** aim of this article is to reveal how spring grass fires affect the abandoned arable lands in the study area at the landscape and local ***:A region of 265.5 km2 located in the south of moscow was *** the landscape scale,we analyzed the spatial characteristics of the area in relation with a 30-year history of spring fire events extracted from the Landsat archive,and climatic *** regression was *** the local scale,we sampled soil and vegetation at two sites and in three biotopes at each site:mature forest and two neighboring biotopes affected and unaffected by *** species diversity,soil quality,and relationship between soil and vegetation were assessed by ANOVA,v test,NmDS,and ***:Abandoned lands covered 39%of the study area and not less than 72% of these were affected by grass fires,happening mainly between 1998 and *** causes the ignition of the field layer accidentally,but the area over which the fire spreads is determined by climatic factors and the presence of flammable material(dry grass and litter)for *** march temperatures and low precipitation values in April increase the inflammability of dry grasses which are abundant on the former *** a result,burnt areas are steadily expanding in abandoned lands where trees are *** abandoned lands that were either affected or unaffected by fires,two different plant communities developed,respectively:grassy vegetation mainly dominated by Calamagrostis epigeios and young forest of pioneer trees with high crown *** all soil variables were statistically diffe

关键词： soil forest landscape

measuring frailty in patients with severe aortic stenosis:a comparison of the edmonton frail scale with modified fried frailty assessment in patients undergoing transcatheter aortic valve replacement

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Journal of Geriatric Cardiology 2020年第7期17卷 441-446页

作者： Francisco J Romeo maximiliano Smietniansky mariela Cal Cristian Garmendia Juan m Valle Raleigh Ignacio mSeropian mariano Falconi Pablo Oberti vadim Kotowicz Carla RAgatiello Daniel H Berroca Division of Interventional Cardiology Hospital Italiano de Buenos AiresBuenos AiresArgentina Division of Internal medicine and Geriatrics Hospital Italiano de Buenos AiresBuenos AiresArgentina Division Cardiology Hospital Italiano de Buenos AiresBuenos AiresArgentina Division of Cardiovascular Surgery Hospital Italiano de Buenos AiresBuenos AiresArgentina

Frailty is generally defined as a clinical syndrome of decreased physiologic reserve which drives to increased vulnerability and susceptibility to different stressors together with poor recovery to homeostasis.[1]The relevance of frailty status in a wide range of prospective cohorts is mostly related to an increasing burden in both mortality,hospital readmissions,disability,and falls.

关键词： Aortic stenosis Frailty Transcatheter aortic valve replacement