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HB-2 high-velocity correlation model at high angles of attack in supersonic wind tunnel tests

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Chinese Journal of Aeronautics 2019年第7期32卷 1565-1576页

作者： Djordje vukovi? Dijana DAMLJANOVI? Department of Experimental Aerodynamics Military Technical InstituteVojnotehnicki Institut

Responding to a need for experimental data on a standard wind tunnel model at high angles of attack in the supersonic speed range, and in the absence of suitable reference data, a series of tests of two HB-2 standard models of different sizes was performed in the T-38 trisonic wind tunnel of Vojnotehnickˇi Institut(VTI), in the Mach number range 1.5–4.0, at angles of attack up to+30°. Tests were performed at relatively high Reynolds numbers of 2.2 millions to 4.5 millions(based on model forebody diameter). Results were compared with available low angle of attack data from other facilities, and, as a good agreement was found, it was assumed that, by implication, the obtained high angle of attack results were valid as well. Therefore, the results can be used as a reference database for the HB-2 model at high angles of attack in the supersonic speed range, which was not available before. The results are presented in comparison with available reference data, but also contain data for some Mach numbers not given in other publications.

关键词： Base pressure Experimental aerodynamics High angle of attack Standard model Wind tunnel

Effect of water matrices on removal of veterinary pharmaceuticals by nanofiltration and reverse osmosis membranes

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Journal of Environmental Sciences 2011年第8期23卷 1299-1307页

作者： Davor Dolar Ana vukovi Danijela Aperger Kreimir Kouti Department of Physical Chemistry Faculty of Chemical Engineering and Technology Maruliev trg 19 10000 Zagreb Croatia Department of Analytical Chemistry Faculty of Chemical Engineering and Technology Maruliev trg 19 10000 Zagreb Croatia

This study explored the removal of five veterinary pharmaceuticals （VPs）（sulfamethoxazole （SMETOX）, trimethoprim （TMP）, ciprofloxacin （CIPRO）, dexamethasone （DEXA） and febantel （FEBA）） from different water matrices （Milli-Q water, model water, tap water and real pharmaceutical wastewater using four types of nanofiltration （NF） membranes （NF90, NF270, NF and HL） and two reverse osmosis （RO） membranes （LFC-1 and XLE）. All VPs were added to different water matrices at a concentration of 10 mg/L. Rejections of VPs and water flux were measured. The rejection increased with increase of molecular weight. The highest rejections were obtained with RO membranes （LFC-1, XLE） and tight NF （NF90） membrane. In general, the rejection of VPs was higher in model water and tap water than in Milli-Q water, but the water flux was lower. This was mainly explained by ion adsorption inside the membranes pores. Narrower pore size counteracted the effect of presence of low concentration of natural organic matter （NOM） in tap water. The NOM was assumed to enhance the adsorption of VPs onto membrane surface, increased the size exclusion and electrostatic repulsion also appeared during the transport. Investigated water matrices had influence on water flux decline due to their complexity.

关键词： veterinary pharmaceuticals water matrix RO/NF treatment rejection

Interplay of SOX transcription factors and microRNAs in the brain under physiological and pathological conditions

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Neural Regeneration Research 2022年第11期17卷 2325-2334页

作者： Milena Stevanovic Danijela Stanisavljevic Ninkovic marija Mojsin Danijela Drakulic marija Schwirtlich Laboratory for Human Molecular Genetics Institute of Molecular Genetics and Genetic EngineeringUniversity of BelgradeBelgradeSerbia University of Belgrade Faculty of BiologyBelgradeSerbia Serbian Academy of Sciences and Arts BelgradeSerbia

Precise tuning of gene expression,accomplished by regulato ry networks of transcription factors,epigenetic modifiers,and microRNAs,is crucial for the proper neural development and function of the brain *** SOX transcription factors are involved in regulating diverse cellular processes during embryonic and adult neurogenesis,such as maintaining the cell stemness,cell prolife ration,cell fate decisions,and terminal diffe rentiation into neurons and glial *** represent a class of small non-coding RNAs that play important roles in the regulation of gene *** with other gene regulatory factors,microRNAs regulate different processes during neurogenesis and orchestrate the spatial and temporal expression important for *** emerging data point to a complex regulatory network between SOX transcription factors and microRNAs that govern distinct cellular activities in the developing and adult *** SOX/mic roRNA interplay in signaling pathways that influence the homeostasis and plasticity in the brain has been revealed in various brain pathologies,including neurodegenerative disorders,traumatic brain injury,and *** strategies that target SOX/microRNA interplay have emerged in recent years as a promising tool to target neural tissue regeneration and enhance neuro restoration.N umerous studies have confirmed complex intera ctions between microRNAs and SOX-specific mRNAs regulating key features of *** in mind the crucial roles of SOX genes and microRNAs in neural development,we focus this review on SOX/microRNAs interplay in the brain during development and adulthood in physiological and pathological *** focus was made on their interplay in brain pathologies to summarize current knowledge and highlight potential future development of molecular therapies.

关键词： dysregulation of miRNA expression glioblastoma gliogenesis glioma stem cells ischemic stroke neural stem cells neural tissue regeneration neurodegenerative diseases neurodevelopment neurogenesis SOX/miRNA interplay traumatic brain injury

Short-circuit Analysis in Large-scale Distribution Systems With High Penetration of Distributed Generators

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IEEE/CAA Journal of Automatica Sinica 2017年第2期4卷 243-251页

作者： Luka V.Strezoski marija D.Prica IEEE Case School of Engineering Case Western Reserve University

In this paper a short-circuit computation(SCC) procedure for large-scale distribution systems with high penetration of distributed generators based on contemporary technologies is proposed. The procedure is suitable for real-time *** of modern distributed generators differs from the modeling of traditional synchronous and induction ***, SCC procedures found on the presumption of distribution systems with only traditional generators are not suitable in nowadays systems. In the work presented in this paper, for computation of the state of the system with short-circuit, the improved backward/forward sweep(IBFS) procedure is *** results show that the IBFS procedure is much more robust than previous SCC procedures, as it takes into account all distribution system elements, including modern distributed generators.

关键词： Distributed generation(DG) distribution system distribution management system(DMS) short-circuit computation

On cancer,stemness,and deep evolutionary homologies

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Genes & Diseases 2023年第4期10卷 1143-1144页

作者： Zoran Ivanovic marija Vlaski-Lafarge Research Department New Aquitaine Branch of French Blood Institute(EFS)BordeauxCS***France

Recently,Niculescu published an interesting paper^(1)con-cerning“deep homologies”between the formation of cancer stem cells by polyploidization and reproductive polyploidization of *** life cycle of both sys-tems shares the same genetic machinery inherited from the Last Eukaryote Common Ancestor(LECA).This theory claims that cancer is nothing more than the expression of a pre-existing life cycle that was reactivated in“sick and weakened metazoan cell that cannot continue its multi-cellular life and finds itself in the same dead-end situation”.

关键词： cancer homolog nothing

EFFECTS OF SPECTRAL DEPENDENCE IN PASS-THROUGH PHOTON-BASED BIOMEDICAL TRANSILLUMINATION

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Journal of Innovative Optical Health Sciences 2009年第3期2卷 235-244页

作者： PAULINO VACAS-JACQUES marija STROJNIK GONZALO PAEZ Centro de Investigaciones en Optica Apartado Postal 1-94837000LeonGuanajuatoMexico

We have proposed an interferometric setup for biomedical analysis in transillumination *** dependence of optical properties must be considered for selecting source and sam*** expansion of the sample optical properties,around the central wavelength of emission,serves to account for spectral *** spectral values depend on the central moments of the source,and specific constants associated to the optical properties of the *** matching wavelength characteristics of source and sample,a first-order approximation is *** such case,the expected values are exactly the optical properties evaluated at the central ***,in the first-order approximation,the transillumination interferometer yields the integrated attenuation of the sample at the central wavelength of *** verify the latter assertion by performing a wavelength-dependent Monte Carlo analysis to calculate the response of the transillumination *** attenuation coefficients,for imaging and characterization scenarios,are in agreement with the value computed at the central wavelength of the source.

关键词： Transillumination wavelength-dependent Monte Carlo tissue characterization tissue imaging.

Sustainable tourism development in mountain areas in Sumadija and Western Serbia

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Journal of Mountain Science 2021年第3期18卷 735-748页

作者： MILICEVIC Snezana BOSKOVIC Nikola LAKICEVIC marija University of Kragujevac Faculty of Hotel Management and Tourism in Vrnjadka BanjaVojvodanska 5AVrnjadka Banja 36210Serbia University of Kragujevac Faculty of EconomicsLiceja Knezevine Srbije 3Kragujevac 34000Serbia

Sustainable tourism,as an integral part of sustainable development,emerged as a logical outcome of preventing the uncontrolled and excessive use of tourism resources and *** study analyzes whether mountain tourism development in Serbia can be sustainable and feasible in the long *** the heterogeneity of mountains in Serbia in terms of tourism development,the subject of this research is the achieved level of sustainable tourism development in mountains in the most developed and most visited region in Serbia-sumadija and Western Serbia:Zlatibor,Kopaonik,Tara,Zlatar,Mokra Gora and Go?.The sustainable tourism development level was analyzed by using five groups of the EU’s comparative indicators:economic,social,cultural,environmental and tourist satisfaction *** results showed that the development of tourism in the examined mountains is not fully aligned with sustainable *** tourist satisfaction indicator has the most acceptable values,which is a good basis for further harmonization of tourism development on the principles of *** indicators,especially the ratio of overnight stays and accommodation capacities,show the most unacceptable values,which indicate the need for implementing changes in the process of tourism development in the coming *** analysis of sustainable tourism in mountain areas in sumadija and the Western Serbia undoubtfully points out that it is necessary to significantly change the current tourism product portfolio,which implies harmonizing mountain tourism development with global ***,a comparative analysis that looks at the degree of sustainability of mountain tourism in some countries of the Alpine region,such as Switzerland,Austria and Slovenia,contributes to *** more intensive development of tourism throughout the year would significantly improve indicators of sustainable tourism in all analyzed mountain areas of Sumadija and Western *** would improve the

关键词： Sustainable tourism development Mountains Tourism effects Sustainability indicators Sumadija and Western Serbia

Prediction of the surface roughness of wood for machining

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Journal of Forestry Research 2017年第6期28卷 1271-1273页

作者： Damjan Stanojevic marija Mandic Gradimir Danon Srdjan Svrzic High School Applied Professional Studies Filipa Filipovica 20 Vranje 17500 Serbia Faculty of Forestry University of Belgrade Kneza Viseslava 1 Belgrade 11000 Serbia

The surface quality of solid wood is very important for its effective response in manufacturing processes. The effects of feed rate, cutting depth and rake angle on surface roughness and power consumption were investigated and modeled. Neuro-fuzzy methodology was applied and shown that it could be useful, reliable and an effective tool for modeling the surface roughness of ***, the results of the present research can be successfully applied in the wood industry to reduce time, energy and high experimental costs.

关键词： Neuro-fuzzy Forecasting Surface roughness Wood Prediction

Prevalence and Factors Associated with Depression, Anxiety and Stress in IBD Patients Undergoing Intravenous Biological Therapy during the COVID-19 Pandemic-Montenegro Experience

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International Journal of Mental Health Promotion 2022年第4期24卷 551-564页

作者： Brigita Smolović marijaĐurović MilošLukić marija Abramović Damir Muhović Department of Gastroenterohepatology Clinic for Internal MedicineClinical Center of MontenegroPodgorica81000Montenegro Faculty of Medicine University of MontenegroPodgorica81000Montenegro Clinic of Radiology Clinical Center of MontenegroPodgorica81000Montenegro

Throughout its duration,the coronavirus disease 2019(COVID-19)pandemic has been affecting lives worldwide and has had a sizeable impact on mental health,particularly for those who already suffer from a chronic ***,Anxiety and Stress(DAS)are common psychiatric comorbidities in inﬂammatory bowel disease(IBD)*** study aims to determine the prevalence and risk factors for moderate and severe symptoms of DAS in IBD patients have been undergoing intravenous biological therapy(IvBTh)during the COVID-19 *** study was conducted between September 1st and November 30th,2020 at the Clinical Center of Mon-tenegro-IBD unit,where all patients from Montenegro received the registered *** case control study consists of 94 IBD patients that completed a validated questionnaire Depression,Anxiety and Stress Score-21(DASS-21).A total of 59 patients received tumor necrosis factor alpha inhibitors(anti-TNF therapy),while 35 received anti-integrin *** we calculated the DASS-21 score,we divided the patients into two groups:those who had moderate and severe symptoms(if they had any of the mentioned DASS-21 subscale score above limit for moderate or more severe symptoms:DASS-21 Depression,higher than 14;DASS-21 Anxiety,higher than 10 and DASS-21 Stress,higher than 19)and those who did not have signiﬁcant symptoms(DASS-21 subscale score did not exceed the limit).We also examined demographic data,data on IBD characteristics and COVID-19 data and their impact on mental *** statistical processing tests were used to identify risk factors for examined mental *** the DASS-21 criteria,we diagnosed the least moderate depression in 19.1%,anxiety in 14.9%and stress in 20.2%*** multivariate analysis indicated there to be a statistically signiﬁcant relation of being higher at risk of developing depression,anxiety and stress when suffering from an active form of IBD(OR 6.487;95%Cl 1.220–34.500,P=0.028).Almost one t

关键词： Inflammatory bowel disease depression anxiety stress COVID-19