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宫腔内人工受精周期中使用重组卵泡刺激素与尿卵泡刺激素成本效益的比较:一项前瞻性随机研究

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世界核心医学期刊文摘（妇产科学分册） 2005年第4期1卷 39-40页

作者： Gerli s. Casini M.L. Unfer v. 侯巍

To compare the clinical results and the cost effectiveness of urinary FsH and recombinant FsH in ovarian stimulation for IUI cycles. Prospective, randomized trial. University Hospital, Perugia, and ***. Obstetrics and Gynaecology Centre, Rome, Italy. IUI cycles were performed in 67 infertile patients. Protocols of ovarian stimulation with urinary FsH or recombinant FsH were randomly assigned, for a total of 138 cycles performed (67 and 71, respectively). Number of mature follicles, days of stimulation, number of ampules, and IU used per cycle, biochemical/clinical pregnancy rates and costeffectiveness ratio. Follicular development, length of stimulation, pregnancy and delivery rates were not statistically different. Although in the urinary FsH group a significantly higher number of IU of gonadotropins were used (815.5 ±284.9 vs. 596.0 ±253.8), the cost per cycle remained significantly lower (220.73 ±94.72 vs. 318.50 ±125.21). The costeffectiveness ratio was 1,848.61 in the urinary FsH group and 2,512.61 in the recombinant FsH group. Urinary FsH and recombinant FsH are both effective in ovarian stimulation in IUI cycles. The urinary preparation is more cost effective due to the difference of its cost per IU.

关键词：卵泡刺激素人工受精随机研究临床妊娠率成熟卵泡促性腺激素卵巢刺激前瞻性随机试验刺激时间分娩率

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外伤性同侧偏盲

世界核心医学期刊文摘（眼科学分册） 2006年第12期2卷 1-2页

作者： Bruce B.B. Kedar s. v. Biousse 张磊 Neuro-ophthalmology Unit Emory Eye Center 1365-B Clifton Road NE Atlanta GA 30322 United StatesDr.

Objective: To describe the characteristics of patients with homonymous hemianopia from traumatic brain injury (TBI) seen in our unit between 1989 and 2004. Methods: Only patients with a history of TBI, who had detailed clinical information and results of neuroimaging, were included in our study. Demographic characteristics, clinical features, types of v.s.al field defects, location of lesion and evolution of v.s.al field defects were recorded. Results: Of the 880 patients with homonymous hemianopia seen in our unit, 103 patients (112 with homonymous hemianopia) had TBI (74 men and 29 women, mean age 30.7 (sD 15.3) years). Median time from injury to initial v.s.al field testing was 5 (range 0.5-360) months. In all, 64 (57.1%) patients sustained injuries that were motor vehicle-related; 19 (17%) violence-related; 17 (15.2%) due to falls; and 12 (10.7%) because of other blunt head trauma. v.s.al field defects included complete homonymous hemianopia in 44 (39.3%) patients and incomplete homonymous hemianopia in 68 (60.7%) patients. The lesion was occipital in 14 (12.5%) patients, associated with optic radiation in 26 (23.2%) and the optic tract in 12 (10.7%), and multiple in 60 (53.6%). Conclusion: Most cases of homonymous hemianopia from TBI were motor vehicle-related. Patients were younger, more often male, and had multiple brain lesions more often than patients with homonymous hemianopia from causes other than TBI. A median delay of 5 months was observed before the documentation of the homonymous hemianopia, which may have a major effect on the success of rehabilitation and driving training in these young patients.

关键词：外伤性同侧偏盲视野缺损颅脑外伤检查结果神经影像临床资料

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心室辅助装置植入后生物瓣的早期改变

世界核心医学期刊文摘(心脏病学分册) 2007年第9期 47-48页

作者： Butany J. Leong s.W. Rao v. 郭俊 Department of Pathology Toronto General Hospital University Health Network Toronto Canada

心脏生物瓣膜在植入后早期可能出现一些变化,包括血管翳和血栓。当存在左心室辅助装置(LvAD)时,这些改变可能会加快。本文报道1例诊断为扩张型心肌病

关键词：装置心脏瓣膜

Tensor factorization for elucidating mechanisms of piezoresponse relaxation via dynamic Piezoresponse Force spectroscopy

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npj Computational Materials 2020年第1期6卷 723-730页

作者： Kyle P.Kelley Linglong Li Yao Ren Yoshitaka Ehara Hiroshi Funakubo suhas somnath stephen Jesse Ye Cao Ramakrishnan Kannan Rama K.v.s.devan sergei v.Kalinin Center for Nanophase Materials sciences Oak Ridge National LaboratoryOak RidgeTN 37831USA Department of Physics Tsinghua UniversityBeijingChina Department of Materials science and Engineering University of Texas at ArlingtonArlingtonTX 76019USA Department of Communications Engineering National Defense AcademyHashirimizuYokosuka 239-8686Japan Department of Material science and Engineering Tokyo Institute of TechnologyYokohama 226‐8502Japan National Center for Computational sciences Oak Ridge National LaboratoryOak RidgeTN 37831USA Computer science and Mathematics Div.s.on Oak Ridge National LaboratoryOak RidgeTN 37831USA

spatially resolved time and voltage-dependent polarization dynamics in PbTiO3 thin films is explored using dynamic piezoresponse force microscopy(D-PFM)in conjunction with interferometric displacement *** approach giv.s.rise to 4D data sets containing information on bias-dependent relaxation dynamics at each spatial location without long-range electrostatic *** interpret these data sets in the absence of defined physical models,we employ a non-negative tensor factorization method which clearly presents the data as a product of simple behaviors allowing for direct physics ***,we perform phase-field modeling finding the existence of‘hard’and‘soft’domain wall *** approach can be extended to other multidimensional spectroscopies for which even exploratory data analysis leads to unsatisfactory results due to many components in the decomposition.

关键词： relaxation factorization dynamic

对先天性红细胞生成性卟啉病患儿进行非亲属捐献者匹配骨髓的成功移植

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世界核心医学期刊文摘（儿科学分册） 2005年第7期1卷 27-28页

作者： Dupuis-Girod s. Akkari v. Ged C. 高蕊 Immuno-hematologie Pediat.T. Hpital Debrousse 29 rue Soeur Bouvier 6932 Lyon Cedex 05 France

Congenital erythropoietic porphyria (CEP; Günther disease; OMIM 263700) is a rare autosomal recessive disorder caused by a deficiency of uroporphyrinogen III synthase (UROs).The deficiency of this enzyme is associated with lifelong overproduction of series I porphyrins which circulate and are deposited in many tissues, causing light-sensitisation and severe damage to skin beginning in *** and scarring of exposed areas may lead to mutilating *** describe two cases: a 4-year-old boy and his first cousin who were cured of CEP by matched unrelated donor bone marrow *** are alive and disease-free 3 and 2 years post-transplant, *** lesions improved *** correction of the enzyme deficiency was confirmed by measuring erythrocyte UROs activity and urinary porphyrin *** was complete for both *** patients were homoallelic for a novel mutation of the UROs gene, the missense mutation ***: Considering the severity of the disease, if HLA-matched sibling donor is not available, haematopoietic stem cell transplantation using amatched unrelated donor should be strongly considered for treating congenital erythropoietic porphyria since this is currently the only known curative therapy.

关键词：捐献者尿卟啉原光过敏酶缺乏血液循环聚合酶嵌合性造血干细胞移植捐赠者错义突变

synthesis, Crystal structure and Biological Activity of N-(tert-butyl)-N'-(2-(4-chlorophenyl)acetyl)-5-methyl-1,2,3-thiadiazole-4-carbohydrazide

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Chinese Journal of structural Chemistry 2013年第5期32卷 673-678页

作者：王盾毛武涛范志金李娟娟黄云宋海斌范谦 Tatiana A. Kalinina Glukhareva Tatiana Morzherin Yury Yur'evich Belskaya N. Pavlovna Bakulev v. Alekseevich Department of Plant Pathology Sichuan Agricultural University state Key Laboratory of Elemento-organic Chemistry Nankai University sichuan Functional Heterocyclic Compounds Engineering Technology Research Center Lier Chemicals Co.Ltd. The Ural Federal University Named after the First President of Russia B. N. Yeltsin

The title compound N-（tert-butyl）-N＇-（2-（4-chlorophenyl）acetyl）-5-methyl-1,2,3-thiadiazole-4-carbohydrazide （C16H19ClN4NaO2s, Mr = 366.86） has been synthesized, and its structure was characterized by IR, 1H NMR, H RMs and single-crystal X-ray diffraction. The crystal of the title compound belongs to triclinic, space group Pī with a = 8.464（2）, b = 10.192（2）, c = 11.757（2）, α = 68.48（3）, β = 76.31（3）, γ = 80.86（3）°, Z = 2, v = 2024.6（10） 3, Dc = 1.333 g/cm3, μ = 0.339 mm-1, F（000） = 384, R = 0.0450 and wR （Ⅰ 〉 2σ（Ⅰ）） = 0.1234. X-ray analysis indicates one N-H…N intermolecular hydrogen bond and no π-π stacking interactions are observed in this crystal structure. The preliminary biological test shows that the title compound has fungicidal activity and antivirus activities against tobacco mosaic virus.

关键词： X-ray diffraction crystal structure synthesis 1,2,3-thiadiazole biological activity

A symmetric MnO_2/MnO_2 flexible solid state supercapacitor operating at 1.6v with aqueous gel electrolyte

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Journal of Energy Chemistry 2016年第3期25卷 463-471页

作者： Nilesh R.Chodankar Deepak P.Dubal Girish s.Gund Chandrakant D.Lokhande Thin Film Physics Laboratory Department of Physics Shivaji University Catalan Institute of Nanoscience and Nanotechnology CIN2 ICN2 (CSIC-ICN) Campus UAB

The demand of microelectronic devices postulated high energetic flexible energy storage devices. Flexible solid state supercapacitor is flawless possible candidate to fulfill the requirement of microelectronic devices. This inv.s.igation provides practical evidence of the use of flexible solid state supercapacitors based on MnOelectrodes with polyvinylpyrrolidone(PvP)-Li ClOgel electrolyte. Initially, different acid mediated growths of MnOhave been carried. Later, the electrochemical performances of MnOelectrodes have been carried out. Impressively, the fabricated symmetric flexible solid state supercapacitor(Fss-sC) device demonstrates the highest operating potential window of 1.6 v with extended cycling stability. Moreover, the cell exhibits high energy density of 23 Wh/kg at power density of 1.9 k W/kg. It is interesting to note that the device shows excellent flexibility upon bending at angle of 180° for number of times. These results clearly evidenced those symmetric Fss-sC devices based on MnOelectrodes are promising energy storage devices for microelectronic applications.

关键词： MnO_2 thin film Polymer gel electrolyte Flexible-all-solid-state supercapacitors

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稀土金属改善车轴钢疲劳强度

稀土 1981年第4期 72-73页

作者： s.K.Kang K.v.Crow 李培良

已经证明夹杂物诸特性如化学性质、数量、分布、形态和塑性等是决定钢的机械性能的重要参数。近来,稀土金属处理已成功地用于控制硫化物夹杂的形态以及降低各种铁和钢中的氧与硫的含量。钢中加稀土的许多有益作用,如显著改善延性、横向... 详细信息

已经证明夹杂物诸特性如化学性质、数量、分布、形态和塑性等是决定钢的机械性能的重要参数。近来,稀土金属处理已成功地用于控制硫化物夹杂的形态以及降低各种铁和钢中的氧与硫的含量。钢中加稀土的许多有益作用,如显著改善延性、横向冲击强度、焊接时的层状撕裂敏感性以及弯曲成形性已有报导。作者以前报导过稀土处理的轨

关键词：车轴钢疲劳断口稀土夹杂物稀土处理疲劳强度力学强度稀土金属

伴发或不伴发临界性早产儿视网膜病变的低出生体重儿童10岁时健康相关生活质量

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世界核心医学期刊文摘（眼科学分册） 2005年第4期1卷 27-28页

作者： Quinn G.E. Dobson v. saigal s. 张自峰 Div.s.on of Pediatric Ophthalmology Children’ s Hospital of Philadelphia One Children’ s Center Philadelphia PA 19104 United States Dr

Objective: To describe parental perspectiv.s.on health status and health- related quality of life (HRQL) at age 10 years in children with birth weights less than 1251 g who participated in the multicenter Cryotherapy for Retinopathy of Prematurity (CRYO- ROP) study. Methods: In 244 participants in the randomized CRYO- ROP trial and 102 CRYO- ROP participants who did not develop ROP, the Health Utilities Index (HUI)- system was used to characterize health status for the following 8 attributes: v.s.on, hearing, speech, ambulation, dexterity, emotion, cognition, and pain. Using a utility formula, HRQL was determined for each child on a scale from 0.0 (dead) to 1.00 (perfect health). Results: The proportion of the ROPrandomized group with limitations in 4 attributes or more was 20.6% compared with 2.0% for the no- ROP group. Within the ROP- randomized group, the proportion of “ sighted” children with limitations in 4 attributes or more was 6.4% vs 46.5% in the “ blind/low v.s.on” group. The median HRQL score for the ROP- randomized children was lower than for the no- ROP children (0.72 vs 0.97, P score for the sighted- randomized children was 0.87 vs 0.27 for the blind/low v.s.on children (P sions: Threshold ROP was associated with functional limitations in health attributes and reduction in HRQL scores at age 10 years. Furthermore, among children who developed threshold ROP, a greater reduction in HRQL scores was found among children with a poor v.s.al outcome compared with those with better sight.

关键词：生活质量临界性功能限制冷冻治疗随机化随机试验于非