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Development of creative problem solvingbased framework for site planning in hill areas

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Frontiers of Architectural Research 2020年第2期9卷 450-466页

作者： N.Kapoor v.K.bansal M.Jain Architecture Department National Institute of Technology(NIT)HamirpurHimachal Pradesh177005India Department of Civil Engineering National Institute of Technology(NIT)HamirpurHimachal Pradesh177005India School of Planning and Architecture(SPA) VijaywadaAndhra Pradesh520008India

The growing urbanization of hill towns results in an increasing demand for infrastructural *** facilities are generally planned without considering the effects of the surroundings as well as their effects on the sensitive ecosystem of hill *** planning decisions are taken on the basis of judgment and experience of planners in the absence of a rational and quantitative framework for ensuring the sustainable development of hill *** scenario generates the need for an efficient site planning *** planning is a creative problem solving(CPS)***,in the current study,the CPSbased framework is developed as ***,existing CPS-based frameworks for planning and designing are ***,the framework is developed for site planning in hill ***,the developed framework is validated through planning infrastructural facilities of an institutional campus on a site located in hill *** major strength of the developed framework includes three cycles,namely,understand,process,and *** planning decisions are taken through the generation of alternate scenarios and their subsequent evaluation on the basis of impact on the sensitive ecosystem of hill areas.

关键词： Site planning Creative problem solving framework Analytic hierarchy process Geographic information system

In Silico Characterization and Homology Modeling of Thylakoidbound Ascorbate Peroxidase from a Drought Tolerant Wheat Cultivar

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Genomics, Proteomics & Bioinformatics 2009年第4期7卷 185-193页

作者： A. Katiyar S.K. Lenka K. Lakshmi v. Chinnusamy K.C. bansal National Research Centre on Plant Biotechnology Indian Agricultural Research Institute Department of Botany and Plant Sciences University of CaliforniaRiverside

Ascorbate peroxidase, a haem protein （EC 1.***.1.11）, efficiently scavenges hydrogen peroxide （H2O2） in cytosol and chloroplasts of plants. In this study, a fulllength coding sequence of thylakoid-bound ascorbate peroxidase cDNA （TatAPX） was cloned from a drought tolerant wheat cultivar C306. Homology modeling of the TatAPX protein was performed by using the template crystal structure of chloroplastic ascorbate peroxidase from tobacco plant （PDB： IIYN）. The model structure was further refined by molecular mechanics and dynamic methods using various tools such as PROCHECK, ProSA and verify3D. The predicted model was then tested for docking with H2O2, the substrate for TatAPX enzyme. The results revealed that Arg233 and Glu255 in the predicted active site of the enzyme are two important amino acid residues responsible for strong hydrogen bonding affinity with H2O2, which might play an important role in scavenging of H2O2 from the plant system.

关键词： ascorbate peroxidase wheat molecular modeling docking

Four new degradation products of doxorubicin:An application of forced degradation study and hyphenated chromatographic techniques

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Journal of Pharmaceutical Analysis 2015年第5期5卷 285-295页

作者： Dheeraj Kaushik Gulshan bansal Department of Pharmaceutical Sciences and Drug Research Punjabi University

Forced degradation study on doxorubicin （DOX） was carried out under hydrolytic condition in acidic, alkaline and neutral media at varied temperatures, as well as under peroxide, thermal and photolytic conditions in accordance with International Conference on Harmonization （ICH） guidelines Q1（R2）. It was found extremely unstable to alkaline hydrolysis even at room temperature, unstable to acid hy- drolysis at 80 ℃, and to oxidation at room temperature. It degraded to four products （O-I-O-Iv） in oxidative condition, and to single product （A-l） in acid hydrolytic condition. These products were re- solved on a C8 （150 mm × 4.6 mm, 5μm） column with isocratic elution using mobile phase consisting of HCOONH4 （10 mM, pH 2.5）, acetonitrile and methanol （65：15：20, v/v/v）. Liquid chromatography-pho- todiode array （LC-PDA） technique was used to ascertain the purity of the products noted in LC-Uv chromatogram. For their characterization, a six stage mass fragmentation （MS6） pattern of DOX was outlined through mass spectral studies in positive mode of electrospray ionization （＋ESI） as well as through accurate mass spectral data of DOX and the products generated through liquid chromato- graphy-time of flight mass spectrometry （LC-MS-TOF） on degraded drug solutions. Based on it, O-I-O-Iv were characterized as 3-hydroxy-9-desacetyldoxorubicin-9-hydroperoxide, l-hydroxy-9-desacetyldox- orubicin-9-hydroperoxide, 9-desacetyldoxorubicin-9-hydroperoxide and 9-desacetyldoxorubicin, re- spectively, whereas A-I was characterized as deglucosaminyl doxorubicin. While A-I was found to be a pharmacopoeial impurity, all oxidative products were found to be new degradation impurities. The mechanisms and pathways of degradation of doxorubicin were outlined and discussed.

关键词： DoxorubicinTOFForced degradationLiquid chromatographyDegradation productMass fragmentation pattern

Measurement of the integrated luminosity of the Phase 2 data of the Belle Ⅱ experiment

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Chinese Physics C 2020年第2期44卷 1-12页

作者： F.Abudinén I.Adachi P.Ahlburg H.Aihara N.Akopov A.Aloisio F.Ameli L.Andricek N.Anh Ky D.M.Asner H.Atmacan T.Aushev v.Aushev T.Aziz K.Azmi v.Babu S.Baehr S.Bahinipati A.M.Bakich P.Bambade Sw.Banerjee S.bansal v.bansal M.Barrett J.Baudot A.Beaulieu J.Becker P.K.Behera J.v.Bennett E.Bernieri F.U.Bernlochner M.Bertemes M.Bessner S.Bettarini v.Bhardwaj F.Bianchi T.Bilka S.Bilokin D.Biswas G.Bonvicini A.Bozek M.Bračko P.Branchini N.Braun T.E.Browder A.Budano S.Bussino M.Campajola L.Cao G.Casarosa C.Cecchi D.Červenkov M.-C.Chang P.Chang R.Cheaib v.Chekelian Y.Q.Chen Y.-T.Chen B.G.Cheon K.Chilikin H.-E.Cho K.Cho S.Cho S.-K.Choi S.Choudhury D.Cinabro L.Corona L.M.Cremaldi S.Cunliffe T.Czank F.Dattola E.De La Cruz-Burelo G.De Nardo M.De Nuccio G.De Pietro R.de Sangro M.Destefanis S.Dey A.De Yta-Hernandez F.Di Capua S.Di Carlo J.Dingfelder Z.Doležal I.Domínguez Jiménez T.v.Dong K.Dort S.Dubey S.Duell S.Eidelman M.Eliachevitch T.Ferber D.Ferlewicz G.Finocchiaro S.Fiore A.Fodor F.Forti A.Frey B.G.Fulsom M.Gabriel E.Ganiev M.Garcia-Hernandez R.Garg A.Garmash v.Gaur A.Gaz U.Gebauer A.Gellrich J.Gemmler T.Geßler R.Giordano A.Giri B.Gobbo R.Godang P.Goldenzweig B.Golob P.Gomis P.Grace W.Gradl E.Graziani D.Greenwald C.Hadjivasiliou S.Halder K.Hara T.Hara O.Hartbrich K.Hayasaka H.Hayashii C.Hearty M.T.Hedges I.Heredia de la Cruz M.Hernández villanueva A.Hershenhorn T.Higuchi E.C.Hill H.Hirata M.Hoek S.Hollitt T.Hotta C.-L.Hsu Y.Hu K.Huang T.Iijima K.Inami G.Inguglia J.Irakkathil Jabbar A.Ishikawa R.Itoh M.Iwasaki Y.Iwasaki S.Iwata P.Jackson W.W.Jacobs D.E.Jaffe E.-J.Jang H.B.Jeon S.Jia Y.Jin C.Joo J.Kahn H.Kakuno A.B.Kaliyar G.Karyan Y.Kato T.Kawasaki H.Kichimi C.Kiesling B.H.Kim C.-H.Kim D.Y.Kim S.-H.Kim Y.K.Kim Y.Kim T.D.Kimmel K.Kinoshita C.Kleinwort B.Knysh P.Kodyš T.Koga I.Komarov T.Konno S.Korpar D.Kotchetkov N.Kovalchuk T.M.G.Kraetzschmar P.Križan R.Kroeger J.F.Krohn P.Krokovny W.Kuehn T.Kuhr M.Kumar R.Kumar K.Kumara S.Kurz A.Kuzmin Y.-J.Kwon S.Lacaprara Y.-T.Lai C.La Licata K.Lalwani L.Lanceri J.S.Lange K.Lautenbach I.-S.Le Beihang University Beijing 100191 Brookhaven National Laboratory UptonNew York 11973 Budker Institute of Nuclear Physics SB RAS Novosibirsk 630090 Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional Mexico City 07360 Faculty of Mathematics and Physics Charles University12116 Prague Chiba University Chiba 263-8522 Consejo Nacional de Ciencia y Tecnología Mexico City 03940 Deutsches Elektronen–Synchrotron 22607 Hamburg Duke University DurhamNorth Carolina 27708 Earthquake Research Institute University of TokyoTokyo 113-0032 Forschungszentrum Jülich 52425 Jülich Department of Physics Fu Jen Catholic UniversityTaipei 24205 Key Laboratory of Nuclear Physics and Ion-beam Application(MOE)and Institute of Modern Physics Fudan UniversityShanghai 200443 II.Physikalisches Institut Georg-August-Universität Göttingen37073 Göttingen Gifu University Gifu 501-1193 The Graduate University for Advanced Studies(SOKENDAI) Hayama 240-0193 Gyeongsang National University Jinju 52828 Department of Physics and Institute of Natural Sciences Hanyang UniversitySeoul 04763 High Energy Accelerator Research Organization(KEK) Tsukuba 305-0801 J-PARC Branch KEK Theory CenterHigh Energy Accelerator Research Organization(KEK)Tsukuba 305-0801 Indian Institute of Science Education and Research Mohali SAS Nagar140306 Indian Institute of Technology Bhubaneswar Satya Nagar 751007 Indian Institute of Technology Hyderabad Telangana 502285 Indian Institute of Technology Madras Chennai 600036 Indiana University BloomingtonIndiana 47408 Institute for High Energy Physics Protvino 142281 Institute of High Energy Physics Vienna 1050 Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049 Institute of Particle Physics(Canada) VictoriaBritish Columbia V8W 2Y2 Institute of Physics Hanoi Instituto de Fisica Corpuscular Paterna 46980 INFN Laboratori Nazionali di Frascati I-00044 Frascati INFN Sezione di Napoli I-80126 Napoli INFN Sezione di Padova I-35131 Padova INFN Sezione di Perugia I-06123 Perugia

From April to July 2018,a data sample at the peak energy of the T(4 S) resonance was collected with the Belle Ⅱ detector at the SuperKEKB electron-positron *** is the first data sample of the Belle Ⅱ *** Bhabha and digamma events,we measure the integrated luminosity of the data sample to be(496.3±0.3±3.0) pb-1,where the first uncertainty is statistical and the second is *** work provides a basis for future luminosity measurements at Belle Ⅱ.

关键词： luminosity Bhabha digamma Belle II

Efficacy and safety of oxybutanin and tolterodine in pediatrics patients suffering from urinary incontinence

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Efficacy and safety of oxybutanin and tolterodine in pediatr...

A Motor Management Strategy for Optimising Energy Use and Reducing Life Cycle Costs

第十五届世界药理学大会国际儿科药理卫星会议

作者： Medhi B bansal v Prakash O Narsimhan KL Postgraduate Institute of Medical Education ＆ Research Chandigarh 160012India Postgraduate Institute of Medical Education ＆ Research Chandigarh 160012India Postgraduate Institute of Medical Education ＆ Research Chandigarh 160012India Department of Clinical Pharmacology and Pediatric Surgery

＜正＞Introduction: Urinary incontinence is a important disabling condition in the children which can be pathological in etiology. Oxybutanin and tolterodine are two anticholinergic drugs which are routinely prescribed for symptomatic treatment. So aim of present study was to evaluate efficacy and safety of these two drugs in short term use in pediatric patients. Materials and Methods: The patients attending outpatients department of pediatric surgery who were prescribed oxybutanin and tolterodine were followed for one month. Urodynamics at baseline and after one month were recorded. Patents were evaluated for any observed adverse drug reaction and quality of life during one month of treatment period. Results: Total 41 patients were observed for one month. 24 were prescribed oxybutanin and 17 tolterodine. Patients suffering from urinary incontinence were diagnosed as having posterior urethral valves and maningomyeolcele. Both the drugs were well tolerated and relatively efficacious. There was significance improvement in the quality of life of 39 patients within three days of therapy as well as urodynamics after completion of one month treatment. Two patients did show any improvement. Total three events were reported in tolterodine group（fever-1, constipation-1, and redness in the eye-1） and 18 （fever, constipation and redness in the eye in three each, dry mouth and increase in thirst in two each, and one each of headache, decrease sweating, dry cough and altered appetite） in oxybutanin group. Five patients were change the therapy from tolterodine to oxybutanin because of fever and constipation which results improvement of symptoms. Conclusion: Oxybutanin and tolterodine is relatively well tolerated and efficacious in pediatric patients suffering from urinary incontinence for short term of use.

关键词： Urinary incontinence oxybutanin tolterodine

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Journal of Power and Energy Engineering 2014年第4期2卷 448-456页

作者： v. Dlamini R. C. bansal R. Naidoo Department of Electrical Electronic & Computer Engineering University of Pretoria Pretoria South Africa

With increasing energy costs and renewed focus on using energy in ways that support the environment, a structured approach is required to ensure that energy is used efficiently. A comprehensive motor management strategy to reduce motor life cycle costs while increasing reliability is presented. The application of energy management principles is combined with benefits that can be obtained from using energy-efficiency motors. An economic model for determining the optimal time a motor should be replaced with a higher efficiency motor is proposed. The strategy presented incorporates benefits that can be obtained from using in-situ motor efficiency estimation and condition monitoring techniques as part of a motor management system.

关键词： Motor Efficiency Motor Management Maintenance vibration Signature Analysis Energy Efficiency Motor Replacement

Effect of flunixin meglumine alone and in combination on haemodynamics during bovine endotoxic shock and after treatment

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Journal of Biomedical Science and Engineering 2011年第1期4卷 29-33页

作者： D. v. Singh S. K. bansal G. S. Ghumman 不详

To investigate the effect of Flunixin meglumine- a NSAID;alone and in combination with hypertonic saline on endotoxemic buffalo calves, two groups of five apparently healthy male buffalo calves aged be-tween 6-8 months were subjected to I.v. infusion of *** endotoxin at the rate of 5μg/kg BW per hour for 3 hours. A highly significant (P venous pressure (C.v.P) and haemo-globin was observed till the end of endotoxin infusion while respiratory rate was significantly elevated along with a non-significant alteration in rectal tem-perature and hematocrit during the infusion of en-dotoxin. Immediately at the end of endotoxin infusion, flunixin meglumine at the rate of 1.1 mg/kg B.W was infused i.v. in group-I animals and group-II animals were infused with hypertonic saline solution (H.S.S.) at the rate of 4 ml/Kg BW as one time infusion fol-lowed by flunixin meglumine at the rate of 1.1 mg/kg B.W which resulted in increase of various parameters either to normal or very close to normal value while the rectal temperature and haematocrit decreased non-significantly throughout the observation period of 7 hours. No improvement in Hb and respiration was observed consequent to FM administration. Both treatments successfully raised systolic, diastolic, pulse pressure, C.v.P & M.A.P to normal pre-infusion val-ues. From the results of the present investigation, it can be concluded that i.v. infusion of FM alone and in combination with hypertonic saline solution in en-dotoxemic buffalo calves effectively restores the various hemodynamic parameters close to normal pre-infusion values and it can be used as immediate resuscitation measure to provide the clinician valu-able time to plan further long term treatment.

关键词： Buffalo Calves Flunixin Meglumine Haemodynamics Hypertonic Saline Endotoxic Shock

An Introduction to Information Sets with an Application to Iris Based Authentication

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Journal of Modern Physics 2020年第1期11卷 122-144页

作者： Madasu Hanmandlu Mamta bansal Shantaram vasikarla CSE Department MVSR Engineering College Hyderabad India Hella India Automotive Pvt. Ltd. Pune India CSE Department California State University Los Angels CA USA

This paper presents the information set which originates from a fuzzy set on applying the Hanman-Anirban entropy function to represent the uncertainty. Each element of the information set is called the information value which is a product of the information source value and its membership function value. The Hanman filter that modifies the information set is derived by using a filtering function. Adaptive Hanman-Anirban entropy is formulated and its properties are given. It paves the way for higher form of information sets called Hanman transforms that evaluate the information source based on the information obtained on it. Based on the information set six features, Effective Gaussian Information source value (EGI), Total Effective Gaussian Information (TEGI), Energy Feature (EF), Sigmoid Feature (SF), Hanman transform (HT) and Hanman Filter (HF) features are derived. The performance of the new features is evaluated on CASIA-IRIS-v3-Lamp database using both Inner Product Classifier (IPC) and Support vector Machine (SvM). To tackle the problem of partially occluded eyes, majority voting method is applied on the iris strips and this enables better performance than that obtained when only a single iris strip is used.

关键词： Information Sets Energy Feature (EF) Sigmoid Feature (SF) Hanman Trans-form (HT) Hanman Filter (HF) Hanman-Anirbanentropy Function

Role of Joshi＇s external stabilization system with percutaneous screw fixation in high-energy tibial condylar fractures associated with severe soft tissue injuries

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Chinese Journal of Traumatology 2015年第6期18卷 326-331页

作者： Ashish Kumar Gupta Rahul Sapra Rakesh Kumar Som Prakash Gupta Devwart Kaushik Sahil Gaba Mahesh Chand bansal Ratan Lal Dayma Department Of Orthopedics Bhagwan Mahavir Hospital New Delhi 110088 India Department of Orthopedics SMS Medical College & Hospitals Jaipur Jaipur Rajasthan 302004 India

Purpose： The treatment of high-energy tibial condylar fractures which are associated with severe soft tissue injuries remains contentious and challenging. In this study, we assessed the results of Joshi＇s external stabilization system （JESS） by using the principle of ligamentotaxis and percutaneous screw fixation for managing high-energy tibial condylar fractures associated with severe soft tissue injuries. Methods： Between June 2008 and June 2010, 25 consecutive patients who were 17-71 years （mean, 39.7）, underwent the JESS fixation for high-energy tibial condylar fractures associated with severe soft tissue injuries. Out of 25 patients, 2 were lost during follow-up and in 1 case early removal of frame was done, leaving 22 cases for final follow-up. Among them, 11 had poor skin condition with abrasions and blisters and 2 were open injuries （Gustilo-Anderson grade I ＆ 11）. The injury mechanisms were motor vehicle accidents （n - 19）, fall from a height （n = 2） and assault （n - 1）. The fractures were classified according to Schatzker classification system. Results： There were 7 type-v, 14 type-vl and 1 type-Iv Schatzker＇s tibial plateau fractures. The average interval between the injury and surgery was 6.8 days （range 2-13）. The average hospital stay was 13 days （range, 7-22）. The average interval between the surgery and full weight bearing was 13.6 weeks （range 11-20）. The average range of knee flexion was 121° （range 105°-135°）. The normal extension of the knee was observed in 20 patients, and an extensor lag of 5°-8° was noted in 2 patients. The complications included superficial pin tract infections （n 4） with no knee stiffness. Conclusion： JESS with lag screw fixation combines the benefit of traction, external fixation, and limited internal fixation, at the same time as allowing the ease of access to the soft tissue for wound checks, pin care, dressing changes, measurement of compartment pressure, and the monitoring of the neurovascular status. In a nutshell, JES

关键词： Tibial plateau fractures External stabilization system Ligamentotaxis