检索结果-南通市图书馆

Management of distal cholangiocarcinoma with arterial involvement: systematic review and case series on the role of neoadjuvant therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal surgery 2024年第8期16卷 2689-2701页

作者： Lewis A Hall Duncan Loader santiago Gouveia Marta Burak James Halle-smith Peter Labib Moath Alarabiyat Ravi Marudanayagam Bobby v Dasari Keith J Roberts syed s Raza Michail Papamichail David C Bartlett Robert P sutcliffe Nikolaos A Chatzizacharias Department of Hepatopancreatobiliary surgery and Liver Transplantation University Hospitals Birmingham NHS Foundation TrustBirmingham B152GWUnited Kingdom Institute of Immunology and Immunotherapy University of BirminghamBirmingham B152TTUnited Kingdom College of Medical and Dental sciences University of BirminghamBirmingham B152TTUnited Kingdom Institute of Clinical sciences University of BirminghamBirmingham B152TTUnited Kingdom

BACKGROUND The use of neoadjuvant therapy(NAT)in distal cholangiocarcinoma(dCCA)with regional arterial or extensive venous involvement,is not widely accepted and evidence is *** To synthesise evidence on NAT for dCCA and present the experience of a highvolume tertiary-centre managing dCCA with arterial *** A systematic review was performed according to PRIsMA guidance to identify all studies reporting outcomes of patients with dCCA who received *** patients from 2017 to 2022 who were referred for NAT for dCCA at our centre were retrospectively collected from a prospectively maintained *** characteristics,NAT type,progression to surgery and oncological outcomes were *** Twelve studies were *** definition of“unresectable”locally advanced dCCA was *** studies reported outcomes for 9 patients who received NAT for dCCA with extensive vascular involvement.R0 resection rate ranged between 0 and 100%but without survival benefit in most *** studies considered either NAT in resectable dCCA or inclusive with extrahepatic *** presented case series includes 9 patients(median age 67,IQR 56-74 years,male:female 5:4)referred for NAT for borderline resectable or locally advanced *** patients progressed to surgery and 2 were *** patient died at 14 months with evidence of recurrence at 6 months and the other died at 51 months following recurrence 6 months *** Evidence for benefit of NAT is *** on criteria for uniform definition of resectability for dCCA is *** propose using the established National-Comprehensive-Cancer-Network®criteria for pancreatic ductal adenocarcinoma.

关键词： Cholangiocarcinoma Neoadjuvant therapy Arterial involvement Locally advanced systematic review

Heavy metal pollution of river water and eco-friendly remediation using potent microalgal species

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Water science and Engineering 2024年第1期17卷 41-50页

作者： Amudham Radha Amal Raj Prabhakaran Mylsamy v.sivasankar B.sathish Kumar Kiyoshi Omine T.G.sunitha Phycological Research Laboratory Research Department of BotanyPachaiyappa's College(Affiliated to University of Madras)Chennai 600030India Research Department of Chemistry Pachaiyappa's College(Affiliated to University of Madras)Chennai 600030India Department of Botany Sri Vidya Mandir Arts&Science College(Autonomous)KatteriUthangarai 636902India Department of Civil Engineering School of Engineering.Nagasaki UniversityNagasaki-Daigaku1-14 Bunkyo-machiNagasaki 8528521Japan

Pollution of rivers is mainly caused by anthropogenic activities such as discharge of effluent from industrial facilities,maintenance of sewage/effluent treatment plants,and dumping of solid waste on river *** study dealt with the pollution issues of the Cooum River in the well-known city of Chennai in south *** samples from 27 locations were collected and analyzed for 12 elements,including Ba,B,and Al,as well as heavy metals such as Pb,Cr,Mn,Fe,Co,Ni,Cu,Zn,and *** samples showed levels of these elements that exceeded World Health Organization *** correlation analysis revealed the inter-dependency among elements,and the contribution of each element based on factor loadings showed its percentage contribution compared to *** samples from six significant locations were chosen for remediation with three algae:Chlorella vulgaris,scenedesmus dimorphus,and Phormedium *** uptake of pollutants led to the continuous growth of algae during the incubation period of 15 d,effectively removing heavy metals from the river *** increasing levels of algal counts and the chlorophyll a content confirmed the algal growth during the incubation period,followed by a declining stage after the incubation *** scanning electron microscopic images of algae before and after the remediation showed no remarkable modification of morphological *** study showed that the uptake of heavy metals using algae is an effective water pollution remediation measure,making the process practicable in the field on a large scale in the near future.

关键词： Heavy metal Cooum river Phycoremediation Microalgae Factor analysis

Electrostatic interaction-mediated 1:1 complexes for high-contrast mitochondrial-targeted phosphorescence bioimaging

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

science China Chemistry 2024年第10期67卷 3406-3413页

作者： Jianshuo Cheng Hao sun Lulu Zhou Glib v.Baryshnikov Mouwei Liu shen shen Hans ?gren Liangliang Zhu state Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular ScienceFudan University Laboratory of Organic Electronics Department of Science and TechnologyLink?ping University Department of Physics and Astronomy Uppsala University

Organelle-targeted imaging can provide information on cellular functions and intracellular interactions, being significant for disease diagnosis. The use of room-temperature phosphorescence(RTP) in organelle-targeted imaging can fully utilize its unique characteristics of long wavelength and deep penetration. However, this technology has long been plagued by insufficient probe targeting and limited luminous intensity. In this work, we prepared a series of complexes composed of multicationic persulfurated arenes and biomacromolecules via electrostatic interactions in 1:1 stoichiometry for high-contrast mitochondrial-targeted RTP imaging. such an electrostatic interaction design effectively prevented the self-aggregation of the probes, which is not conducive to mitochondrial targeting. simultaneously, it suppressed the non-radiative decay to the maximum extent, enabling the probes to exhibit strong RTP signals both in aqueous solution and at the cellular level. Furthermore, the biomacromolecules can serve as carriers for an electrostatic interaction transfer of the persulfurated arenes to mitochondria. This leads to high mitochondrial targeting Pearson's correlation coefficients of the probes and high-contrast RTP imaging effects, as well as the independence of the co-incubated probe concentration. These results provide new insights for the development of targeted imaging technologies.

关键词： room-temperature phosphorescence mitochondrial targeting bioimaging complex electrostatic interaction

superior comprehensive properties of LaFe_(11.8)si_(1.2)/Ce_(60)Co_(40) magnetocaloric composites

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第6期42卷 1073-1086,I0003页

作者： Xichun Zhong Yuanxin Li Yucai Wu Jiaohong Huang Cuilan Liu Jian Liu Zhongwu Liu Minglong Zhong Zhenchen Zhong R.v.Ramanujan school of Materials science and Engineering South China University of TechnologyGuangzhou510640China Baotou Research Institute of Rare Earths Baotou014030China Center for Advanced solidification Technology School of Materials Science and EngineeringShanghai UniversityShanghai200444China Jiangxi KeyLaboratory for Rare Earth Magnetic Materials and Devices&Institute for Rare Earth Magnetic Materials and Devices(IREMMD) Jiangxi University of Science and TechnologyGanzhou341000China school of Materials science and Engineering Nanyang Technological University639798Singapore singapore-HUJ Alliance for Research and Enterprise(sHARE) The Smart Grippers for Soft Robotics(SGSR)ProgrammeCampus for Research Excellence and Technological Enterprise(CREATE)138602Singapor

LaFe_(11.8)si_(1.2)/10 wt%Ce_(60)Co_(40) composites were prepared by spark plasma sintering and subsequent diffusion annealing.A novel core-shell structure is observed with the LaFe11.8si1.2 particles as the core and the(La,Ce)_(2)(Fe,Co,si)_(17)(2:17)phase as the *** diffusion annealing time(t_(a))increases,this core-shell structure is replaced by the formation of the(La,Ce)_(1)(Fe,Co,si)_(13) *** at 1323 K for 12 h results in samples with(-ΔsM)^(max) of 9.30 J/(kg·K)(Δμ0H=2 T),good mechanical properties((σbc)^(max)=402 MPa,ε=4.21%)and thermal conductivity of 8.7 W/(m·K).Thus,bulk composites with excellent comprehensive properties for magnetic refrigeration are obtained in this work.

关键词： LaFe_(11.8)si_(1.2)/Ce_(60)Co_(40)composites spark plasma sintering Diffusion annealing Microstructure evolution Magnetocaloric effect Rareearths

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

告别米格尔街

语数外学习(初中版) 2024年第6期 15-16页

作者： v.s.奈保尔

我的母亲说：“你在这个地方变得太野了，我想你该离开了。”“去哪儿，委内瑞拉吗？”我说。“不，去个别的什么地方。”我说：“那好吧，等你想好了再决定吧。”母亲说：“这事我要去和格涅沙·庞迪特商量一下，他是你爸爸的朋友。

关键词：

Fluoride contamination in groundwater:A global review of the status,processes,challenges,and remedial measures

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Geoscience Frontiers 2024年第2期15卷 1-29页

作者： E.shaji K.v.sarath M.santosh P.K.Krishnaprasad B.K.Arya Manisha s.Babu Department of Geology University of KeralaKariavattom CampusThiruvananthapuramKerala 695581India school of Earth sciences and Resources China University of Geosciences(Beijing)29 Xueyuan RoadBeijing 100083China Department of Earth science University of AdelaideAdelaideSA 5005Australia Department of Geology Central University of KeralaTejaswini HillsPeriyeKasaragodKerala 671316India

Groundwater pollution by fluoride is one of the prime concerns of the world population due to its toxicity,which results in adverse health *** this paper,we review the current scenario of the fluoride contamination of groundwater in various countries across the globe and its impact on human *** the last decade,several newly affected regions have been reported all over the world,with more than 100 countries affected by fluoride contamination in groundwater(concentration exceeding the acceptable limit of 1.5 mg/L defined by the World Health Organization).Fluoride poisoning is mainly due to the unsupervised ingestion of products for dental and oral hygiene and over-fluoridated drinking *** is estimated that more than 200 million people from different countries are affected by fluoriderelated groundwater issues and health *** highest among these are from the countries in Africa(38),Asia(28),and Europe(24),followed by countries like south America(5),North America(3),and Australia(2).The source of fluoride in drinking water is primarily geogenic,together with forage,grasses and grains,tea,and anthropogenic *** countries affected were correlated with climatic zones and geological factors to gain insights into geospatial *** analyses show that most of the fluoride pollution-prone zones are located in high-grade metamorphic terranes with granitoid or alkaline intrusions,geothermal hot springs,and volcanic regions with arid or semi-arid climatic *** study also finds that children across the globe are more vulnerable than adults to fluoride *** review finds that,although there are efficient fluoride removal techniques,including filters with next-generation nanomaterials,to date,there has not been a single technique developed that can claim to be a practically robust solution for fluoride removal from drinking ***,we suggest developing next-generation filters that can retain essential miner

关键词： Fluoride Groundwater Water contamination WHO standards Climate zones Remediation sustainable Development Goals

Enhanced solar Water Desalination by CuCo_(2)s_(4)-decorated Carbon Foam Derived from Waste Plastics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2024年第3期40卷 548-555页

作者： Muzammil HUssAIN Tofik Ahmed sHIFA Pratik v.sHINDE Pankaj KUMAR stefano CENTENARO silvia GROss Elisa MORETTI Alberto vOMIERO Department of Molecular sciences and Nanosystems Ca'Foscari University of VeniceVia Torino 15530172 VeniceItaly Department of Industrial Engineering University of PadovaVia Venezia 135131 PadovaItaly Department of Chemical sciences University of PadovaVia Francesco Marzolo135131 PadovaItaly Division of Materials science Department of Engineering Sciences and MathematicsLulea University of Technology97187 LuleaSweden Center for Cultural Heritage Technologies(CCHT) Istituto Italiano di Tecnologia(IT)Via Torino 15530170 Venezia-MestreItaly

Interfacial solar desalination is an emerging technology for freshwater production,but the finding of novel solar evaporators is still *** the present research,graphitic carbon foam(CF)was synthesized from the upcycling of waste plastic polyethylene terephthalate(PET)waste bottles functionalized with carrollite CuCo_(2)s_(4) as a photothermal *** characterization[X-ray diffraction(XRD),Fourier transform infrared spectroscopy(FTIR),and scanning electron microscopy-energy dispersive spectroscopy(sEM-EDs)]confirms the functionalization of carrollite CuCo_(2)s_(4) on graphitic carbon *** Uv-vis spectroscopy analysis showed an enhanced optical absorption in the Uv-vis-near IR region(>96%)for functionalized CuCo_(2)s_(4)-CF foam compared to carbon foam(67%).The interfacial solar desalination experiment presented a significantly enhanced evaporation rate of 2.4 kg·m^(−2)·h^(−1) for CuCo_(2)s_(4)-CF compared to that of CF(1.60 kg·m^(−2)·h^(−1))and that of CuCo_(2)s_(4)(1.60 kg·m^(−2)·h^(−1)).The obtained results proved that the newly synthesized CuCo_(2)s_(4)-CF from the upcycled plastic into new material for the photothermal desalination process can enhance the practice of a circular economy to produce fresh water.

关键词： Photothermal desalination Cobalt Copper Chalcogenide Waste upcycling Circular economy

In vivo measurement of NADH fluorescence lifetime in skeletal muscle via -ber-coupled time-correlated single photon counting

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Innovative Optical Health sciences 2024年第1期17卷 121-134页

作者： Kathryn M.Priest Jacob v.schluns Nathania Nischal Colton L.Gattis Jeffrey C.Wolchok Timothy J.Muldoon Department of Biomedical Engineering University of Arkansas FayettevilleARUSA

Nicotinamide adenine dinucleotide(NADH)is a cofactor that serves to shuttle electrons during metabolic processes such as glycolysis,the tricarboxylic acid cycle,and oxidative phosphorylation(OXPHOs).NADH is autofluorescent,and itsfluorescence lifetime can be used to infer metabolic dynamics in living ***-coupled time-correlated single photon counting(TCsPC)equipped with an implantable needle probe can be used to measure NADH lifetime in vivo,enabling investigation of changing metabolic demand during muscle contraction or tissue *** study illustrates a proof of concept for point-based,minimally-invasive NADHfluorescence lifetime measurement in *** muscle loss(vML)injuries were created in the left tibialis anterior(TA)muscle of male sprague Dawley *** lifetime measurements were collected before,during,and after a 30 s tetanic contraction in the injured and uninjured TA muscles,which was subsequently-t to a biexponential decay model to yield a metric of NADH utilization(cytoplasmic vs protein-bound NADH,the A11/A22 ratio).On average,this ratio was higher during and after contraction in uninjured muscle compared to muscle at rest,suggesting higher levels of free NADH in contracting and recovering muscle,indicating increased rates of *** injured muscle,this ratio was higher than uninjured muscle overall but decreased over time,which is consistent with current knowledge of inflammatory response to injury,suggesting tissue regeneration has *** data suggest that-ber-coupled TCsPC has the potential to measure changes in NADH binding in vivo in a minimally invasive manner that requires further investigation.

关键词： Glycolysis oxidative phosphorylation energy metabolism volumetric muscle loss

Rigidity symmetry Line for Thermodynamic Fluid Equations-of-state

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Modern Physics 2024年第5期15卷 613-633页

作者： Leslie v. Woodcock Department of Physics University of Algarve Faro Portugal

We report progress towards a modern scientific description of thermodynamic properties of fluids following the discovery (in 2012) of a coexisting critical density hiatus and a supercritical mesophase defined by percolation transitions. The state functions density ρ(p,T), and Gibbs energy G(p,T), of fluids, e.g. COsub>2sub>, Hsub>2sub>O and argon exhibit a symmetry characterised by the rigidity, ω = (dp/dρ)sub>Tsub>, between gaseous and liquid states along any isotherm from critical (Tsub>csub>) to Boyle (Tsub>Bsub>) temperatures, on either side of the supercritical mesophase. Here, using experimental data for fluid argon, we investigate the low-density cluster physics description of an ideal dilute gas that obeys Dalton’s partial pressure law. Cluster expansions in powers of density relate to a supercritical liquid-phase rigidity symmetry (Rs) line (ω = ρsub>rssub>(T) = RT) to gas phase virial coefficients. We show that it is continuous in all derivatives, linear within stable fluid phase, and relates analytically to the Boyle-work line (BW) (w = (p/ρ)sub>Tsub> = RT), and to percolation lines of gas (PB) and liquid (PA) phases by: ρsub>BWsub>(T) = 2ρsub>PAsub>(T) = 3ρsub>PBsub>(T) = 3ρsub>Rssub>(T)/2 for T Tsub>Bsub>. These simple relationships arise, because the higher virial coefficients (bsub>nsub>, n ≥ 4) cancel due to clustering equilibria, or become negligible at all temperatures (0 T Tsub>Bsub>)sub> sub>within the gas phase. The Boyle-work line (p/ρsub>BWsub>)sub>Tsub> is related exactly at lower densities as T → Tsub>Bsub>, and accurately for liquid densities, by ρsub>BWsub>(T) = −(bsub>2sub>/bsub>3sub>)sub>Tsub>. The Rs line, ω(T) = RT, defines a new liquid-density ground-state physical constant (ρsub>Rssub>(0) = (2/3)ρsub>BWsub>(0) for argon). Given the gas-liquid rigidity symmetry, the entire thermodynamic state functions below Tsub>Bsub> are obtainable from bsub>2sub>(T). A BW

关键词： Liquid-state Theory Cluster Physics Percolation Lines Fluid Thermodynamics Boyle Line Rigidity-symmetry Line