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Journal of Southeast University(English Edition) 2008年第S1期24卷 187-190页

作者： N.Mukund Sharma v.prabhu Dev Centre for Post Graduate Studies Surana College

The increased volatility in the foreign exchange market in recent years has increased the foreign exchange risk faced by companies worldwide. This phenomenon holds good in the Indian context also. This paper tries to report on the foreign exchange risk-management practices among Indian IT (information technology) companies. The results are consistent with expectations that foreign exchange risks faced by Indian IT companies is very high especially in the light of the recent appreciation of the rupee against the USD and most of the companies are using all the available techniques to mitigate the risks. The evidence suggests that the forward cover is the most widely used derivative instrument in managing the risks and the respondents taking part in the survey believe that the government is failing in maintaining a stable exchange rate.

关键词： Indian IT companies risk management hedging forward contracts currency options

低级别前列腺癌的主动监测策略:效益和成本效益的比较

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国际医学放射学杂志 2021年第6期 730-730页

作者： S.K.Kang R.D.Mali v.prabhu B.S.Ferket S.Loeb 万怡轩何博

主动监测(AS)是低风险前列腺癌(PC)的推荐治疗方案。MRI、随访频率以及重复活检的前列腺影像报告和数据系统(PI-RADS)评分的监测各不相同。目的在低风险

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前列腺癌:MR扩散加权成像对侵袭性的检测与评估——常规成像与扩散峰度比较

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国际医学放射学杂志 2017年第5期 588-588页

作者： T.Tamada v.prabhu J.Li J.S.Babb S.S.Taneja A.B.Rosenkrantz 张小琨 Department of Radiology Kawasaki Medical School

摘要目的在一个大的病人队列中比较标准DW成像与扩散峰度(DK)成像对前列腺癌(PC)的检测和界定,特别是DK成像潜在的额外价值。材料与方法本回顾性研究经

关键词： ADC GS 良恶性 MR 前列腺癌

Cyanobacterial metabolites as novel drug candidates in corona viral therapies:A review

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Chronic Diseases and Translational Medicine 2022年第3期8卷 172-183页

作者： Srinivasan prabhu Subramaniyan vijayakumar Pabakaran Praseetha Department of Botany Annai Vailankanni Arts and Science CollegeThanjavurTamil NaduIndia Deparment of Botany A.V.V.M Sri Pushpam CollegePoondi(Affiliated to Bharathidasan University)ThanjavurTamil NaduIndi Department of Nnotechnology Noorul Islam Cenire for Higher EducationKumaracolTamil NaduIndia

Most of the medical and nonmedical research labs,all around the world,are racing against time to produce an effective vaccine or an antiviral medicine for coronavirus disease 2019(COvID-19).Conventional medicines and novel nano-materials including chemical and herbal-based compounds are all into positive trials toward coronaviruses and other pandemic *** them,natural immune boosters have attracted physicians because of their longevity and reliability for fewer side *** is a review article with a detailed picture of an unexplored antiviral source with maximum potency in curing viral *** have been known for centuries and are rich in secondary metabolites of proteins,biopeptides,and polysaccharides for prominent antiviral action against chest *** detailed exploratory research is required to purify,scale-up,and commercialize the pharmacologically active agents from these drug reserves.

关键词： antiviral drugs coronavirus covid-19 cyanobacteria

Retreived bacteria from Noctiluca miliaris (green) bloom of the northeastern Arabian Sea

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Chinese Journal of Oceanology and Limnology 2013年第1期31卷 10-20页

作者： BASU Subhajit MATONDKAR SG prabhu FURTADO Irene Department of Microbiology Goa University National Institute of Oceanography (CSIR-India)

在最近的年里， dinoflagellate 夜光虫 miliaris 的季节的花蕾出现了在北阿拉伯的海(NAS ) 开水。这研究从 NAS 的绿夜光虫的一个季节的花蕾提供细菌的第一描述(盐沼草 Porteresia coarctata 的 20 产地沿着 Bakkhali 河口的海岸被调... 详细信息

在最近的年里， dinoflagellate 夜光虫 miliaris 的季节的花蕾出现了在北阿拉伯的海(NAS ) 开水。这研究从 NAS 的绿夜光虫的一个季节的花蕾提供细菌的第一描述(盐沼草 Porteresia coarctata 的 20 产地沿着 Bakkhali 河口的海岸被调查，艇长 Bazar，从 1 月的孟加拉国到 2006 年 12 月。射击 P 的密度。coarctata 到季节被影响并且被发现更高(> 2 500 shoots/m2 ) 在里面在季风季节季风以后、最小；植物在季风前期间在植物的繁殖是特别地活跃的。未葬生物资源与在这个河口的暴露的相比沿着保护的海岸是更大的。地下的生物资源更高(7.75269.53 g DW/m2 ) 上面比那磨擦了(2.20114.75 g DW/m2 ) 。P 的站的庄稼。coarctata 显示出一种否定关系(R =0.77；P < 0.05 ) 与沉积率，当季节的活动影响了沉积时。记录沉积率更低(6.09

关键词：细菌生长阿拉伯海夜光东北部 NaCl溶液地球化学动力学芽孢杆菌属平板计数

Anti-diabetic activity of quercetin extracted from Phyllanthus emblica ***: In silico and in vivo approaches

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Journal of Pharmaceutical Analysis 2018年第2期8卷 109-118页

作者： prabhu Srinivasan S.vijayakumar Swaminathan Kothandaraman Manogar Palani Computational Phytochemistry Lab PG and Research Department of Botany and Microbiology A. V. V. M Sri Pushpam College (Autonomous) Department of Physics RKM Vivekananda College (Autonomous)

In this study, molecular interactions of the ligands, quercetin, gallic acid, and metformin with various diabetes mellitus-related protein targets, such as glycogen phosphorylase and peroxisome proliferatoractivated receptor gamma, were assessed. It was revealed that quercetin possesses good binding affinity to both targets. Quercetin is a major constituent of methanolic extracts of Phyllanthus emblica fruit. The antihyperglycemic effect of quercetin in streptozotocin(STZ)-induced diabetic rats was examined. The isolated quercetin administered at a dose of 75 mg/kg body weight produced a maximum decrease of14.78% in blood glucose levels in the diabetic rats after 7 days of treatment. Furthermore, quercetin doses of 50 and 75 mg/kg were shown to significantly improve the profiles of triglycerides, high-density lipoprotein, very-low-density lipoprotein, low-density lipoprotein, and total cholesterol at the end of the study in STZ-induced diabetic rats. The administration of quercetin(25, 50, and 75 mg/kg body weight)daily for 28 days in STZ-induced diabetic rats resulted in a significant decrease in blood glucose and urine sugar levels, with a considerable rise in plasma insulin and hemoglobin levels. Therefore, quercetin is a potential drug with antidiabetic and antihyperglycemic action mediated by changes in the levels of glucose, cholesterol, and triglycerides as indicated by in silico and in vivo studies.

关键词： Bioactive molecules Glycogen phosphorylase Molecular docking Phyllanthus emblica Quercetin Albino Wister male rats

Enhanced enzymatic removal of anthracene by the mangrove soil-derived fungus,Aspergillus sydowii BPOI

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Frontiers of Environmental Science & Engineering 2020年第6期14卷 223-235页

作者： Paul Olusegun Bankole Kirk Taylor Semple Byong-Hun Jeon Sanjay prabhu Govindwar Department of Pure and Applied Botany College of BiosciencesFederal University of Agriculture AbeokutaOgun State 234039Nigeria Lancaster Environment Centre Lancaster UniversityLancaster LAI 4YQUK Department of Earth Resources and Environmental Engineering Hanyang UniversitySeoul 04763Republic of Korea

The present study investigated the efficiency of Aspergillus sydowii strain bpol(GenBank Accession Number:MK373021)in the removal of anthracene(100 mg/L).Optimal degradation efficiency(98.7%)was observed at neutral pH,temperature(30℃),biomass weight(2 g)and salinity(0.2%w/v)within 72 *** enzyme analyses revealed 131%,107%,and 89%induction in laccase,lignin peroxidase,and manganese peroxidase respectively during anthracene ***,the degradation efficiency(99.8%)and enzyme induction were significantly enhanced with the addition of 100 mg/L of citric acid and glucose to the *** varying anthracene concentrations(100-500 mg/L),the degradation rate constants(K1)peaked with increasing concentration of anthracene while the half-life(t1/2)decreases with increase in anthracene *** of fit(R2=0.976 and 0.982)was observed when the experimental data were subjected to Langmuir and Temkin models respectively which affirmed the monolayer and heterogeneous nature exhibited by *** cells during *** distinct metabolites;anthracene-1,8,9(2H,8aH,9aH)-trione,2,4adihydronaphthalene-1,5-dione,l,3,3a,7a-tetrahydro-2-benzofuran-4,7-dione and 2-hydroxybenzoic acid was obtained through Gas Chromatography-Mass spectrometry(GC-MS).*** exhibited promising potentials in the removal of PAHs.

关键词： Aspergillus sydowii Anthracene Biodegradation Polycyclic aromatic hydrocarbons

A fiber optic biosensor for the detection of cholesterol levels based on chitosan coated long period grating

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Optoelectronics Letters 2016年第1期12卷 23-26页

作者： C.Bobby Mathews T.M.Libish B.Kaushalkumar v.vivek Radhakrishna prabhu P.Radhakrishnan International School of Photonics Cochin University of Science and Technology Kochi 682022 India Muslim Educational Society Collegeof Engineering Kuttippuram 679573 India Robert Gordon University Aberdeen AB107QB UK

A fiber optic sensor for the measurement of total cholesterol is designed and *** developed chitosan coated long period grating(LPG) sensor shows a sensitivity of 5.025×106 pm·m L/g in the measurement range of the *** sensor also shows a linear response in the measured range of cholesterol levels,which is highly desirable for exploitation as a commercial cholesterol sensor.

关键词：胆固醇水平传感器检测长周期光栅壳聚糖纤维光学涂层生物传感器灵敏度

In silico prediction of monovalent and chimeric tetravalent vaccines for prevention and treatment of dengue fever

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The Journal of Biomedical Research 2018年第3期32卷 222-236页

作者： vijayakumar Subramaniyan Ramesh venkatachalam prabhu Srinivasan Manogar Palani Computational Phytochemistry Laboratory P.G. and Research Department of Botany and Microbiology A.V.V.M. Sri Pushpam College (Autonomous)

Reverse vaccinology method was used to predict the monovalent peptide vaccine candidate to produce antibodies for therapeutic purpose and to predict tetravalent vaccine candidate to act as a common vaccine to cover all the dengue virus serotypes. Envelope（E）-proteins of DENv-1-4 serotypes were used for vaccine prediction using NCBI,Uniprot/Swissprot, Swiss-prot viewer, vaxiJen v2.0, TMHMM, BCPREDS, Propred-1, Propred and MHC Pred. Eproteins of DENv-1-4 serotypes were identified as antigen from which T cell epitopes, through B cell epitopes, were predicted to act as peptide vaccine candidates. Each selected T cell epitope of E-protein was confirmed to act as vaccine and to induce complementary antibody against particular serotype of dengue virus. Chimeric tetravalent vaccine was formed by the conjugation of four vaccines, each from four dengue serotypes to act as a common vaccine candidate for all the four dengue serotypes. It can be justifiably concluded that the monovalent 9-mer T cell epitope for each DENv serotype can be used to produce specific antibody against dengue virus and a chimeric common tetravalent vaccine candidate to yield a comparative vaccine to cover any of the four dengue virus serotype. This vaccine is expected to be highly immunogenic against dengue fever.

关键词： dengue serotypes dengue virus vaccine E-proteins MHC Ⅰ and Ⅱ