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Computers, Materials & Continua 2023年第5期75卷 3883-3901页

作者： Ali Akbar Siddique S.M.Umar Talha M.aamir Abeer D.Algarni Naglaa F.Soliman Walid El-Shafai Department of Telecommunication Engineering Sir Syed University of Engineering&TechnologyKarachi75300Pakistan Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Security Engineering Lab Computer Science DepartmentPrince Sultan UniversityRiyadh11586Saudi Arabia Department of Electronics and Electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt

The COVID-19 pandemic has devastated our daily lives,leaving horrific repercussions in its *** to its rapid spread,it was quite difficult for medical personnel to diagnose it in such a big *** who test positive for Covid-19 are diagnosed via a nasal PCR *** comparison,polymerase chain reaction(PCR)findings take a few hours to a few *** PCR test is expensive,although the government may bear expenses in certain ***,subsets of the population resist invasive testing like ***,chest X-rays or Computerized Vomography(CT)scans are preferred in most cases,and more importantly,they are non-invasive,inexpensive,and provide a faster response *** advances in Artificial Intelligence(AI),in combination with state-of-the-art methods,have allowed for the diagnosis of COVID-19 using chest *** article proposes a method for classifying COVID-19 as positive or negative on a decentralized dataset that is based on the Federated learning *** order to build a progressive global COVID-19 classification model,two edge devices are employed to train the model on their respective localized dataset,and a 3-layered custom Convolutional Neural Network(CNN)model is used in the process of training the model,which can be deployed from the *** two edge devices then communicate their learned parameter and weight to the server,where it aggregates and updates the *** proposed model is trained using an image dataset that can be found on *** are more than 13,000 X-ray images in Kaggle Database collection,from that collection 9000 images of Normal and COVID-19 positive images are *** edge node possesses a different number of images;edge node 1 has 3200 images,while edge node 2 has *** is no association between the datasets of the various nodes that are included in the *** doing it in this manner,each of the nodes will have access to a separate image collection that has no correl

关键词： Artificial intelligence deep learning federated learning COVID-19 decentralized image dataset

Treatment outcomes and adverse drug reactions among patients with drug-resistant tuberculosis receiving all-oral,long-term regimens:First record viewing report from Pakistan

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Asian Pacific Journal of Tropical Medicine 2023年第2期16卷 58-64,I0003页

作者： Hira Aslam Asad Omar Razia Fatima Usman Rasool Aashifa Yaqoob Waseem Ullah aamir Khan Yusra Habib Khan Tauqeer Hussain Mallhi Provincial Tuberculosis Control Program Punjab Pakistan Cardio-metabolic Division CCL Research Laboratories Lahore PunjabPakistan Common Management Unit National Tuberculosis Control Program of PakistanIslamabadPakistan Department of Pharmacy Practice Shifa College of Pharmaceutical SciencesShifa Tameer-e-Millat UniversityIslamabadPakistan Association for Social Development IslamabadPakistan Department of Clinical Pharmacy College of PharmacyJouf UniversitySakakaAl-Jouf ProvinceSaudi Arabia

Objective:To assess the effectiveness and adverse drug reactions of all-oral regimens for patients with multidrug-resistant ***:This retrospective study was conducted at 10 Programmatic Management of Drug Resistant Tuberculosis sites in Punjab province of *** receiving treatment for drug resistant tuberculosis from July 2019 to December 2020 with at least interim result i.e.6th month culture conversion or final outcomes(cured,complete,lost to follow-up,failure,death)available,were included in the *** was extracted from electronic data management *** the reporting and management of adverse drug events,active tuberculosis drug safety monitoring and management was implemented across all *** the data was analyzed using SPSS version ***:Out of 947 drug resistant tuberculosis patients included in this study,579(68%)of the patients had final outcomes *** these,384(67.9%)successfully completed their *** of 368(32%)patients who had their interim results available,all had their 6th month culture *** new medications was thought to result in serious adverse outcomes such as QT ***,this study did not record any severe adverse events among ***:All-oral regimens formulation guided by overall treatment effectiveness resulted in treatment outcomes comparable to those obtained with traditional injectable treatment.

关键词： All-oral long-term regimens Long-term regimens Bedaquiline Linezolid Clofazimine Drug resistant tuberculosis Treatment outcomes aDSM

Projections of the transmission of the Omicron variant for Toronto,Ontario,and Canada using surveillance data following recent changes in testing policies

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Infectious Disease Modelling 2022年第2期7卷 83-93页

作者： Pei Yuan Elena Aruffo Yi Tan Liu Yang Nicholas HOgden aamir Fazil Huaiping Zhu Laboratory of Mathematical Parallel Systems(LAMPS) Centre for Diseases ModellingDepartment of Mathematics and StatisticsYork UniversityTorontoONCanada Public Health Agency of Canada(PHAC) OttawaONCanada

At the end of 2021,with the rapid escalation of COVID19 cases due to the Omicron variant,testing centers in Canada were *** alleviate the pressure on the PCR testing capacity,many provinces implemented new strategies that promote self testing and adjust the eligibility for PCR tests,making the count of new cases *** designed a novel compartmental model which captures the new testing guidelines,social behaviours,booster vaccines campaign and features of the newest variant *** better describe the testing eligibility,we considered the population divided into high risk and non-highrisk *** model is calibrated using data from January 1 to February 9,2022,on cases and severe outcomes in Canada,the province of Ontario and City of *** conduct analyses on the impact of PCR testing capacity,self testing,different levels of reopening and vaccination coverage on cases and severe *** results show that the total number of cases in Canada,Ontario and Toronto are 2.34(95%CI:1.22e3.38),2.20(95%CI:1.15e3.72),and 1.97(95%CI:1.13e3.41),times larger than reported cases,*** current testing strategy is efficient if partial restrictions,such as limited capacity in public spaces,are *** more people to have access to PCR reduces the daily cases and severe outcomes;however,if PCR test capacity is insufficient,then it is important to promote self ***,we found that reopening to a pre-pandemic level will lead to a resurgence of the infections,peaking in late March or April *** and adherence to isolation protocols are important supports to the testing policies to mitigate any possible spread of the virus.

关键词： PCR testing Self-testing Booster dose Social behavior Mathematical model COVID-19 Omicron Exit strategy

A Novel Inherited Modeling Structure of Automatic Brain Tumor Segmentation from MRI

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Computers, Materials & Continua 2022年第11期73卷 3983-4002页

作者： Abdullah AAsiri Tariq Ali Ahmad Shaf Muhammad aamir Muhammad Shoaib Muhammad Irfan Hassan A.Alshamrani Fawaz F.Alqahtani Osama M.Alshehri Radiological Sciences Department College of Applied Medical SciencesNajran UniversityNajran61441Saudi Arabia Department of Computer Science COMSATS University IslamabadSahiwal CampusSahiwal57000Pakistan Department of Informatics and Systems University of Management and TechnologyLahore54000Pakistan Electrical Engineering Department College of EngineeringNajran UniversityNajran61441Saudi Arabia Department of Clinical Laboratory Sciences Collage of Applied Medical ScienceNajran UniversityNajranSaudi Arabia

Brain tumor is one of the most dreadful worldwide types of cancer and affects people leading to *** resonance imaging methods capture skull images that contain healthy and affected *** checked the affected tissue in the slice-by-slice manner,which was timeconsuming and hectic ***,auto segmentation of the affected part is needed to facilitate ***,we have considered a hybrid model that inherits the convolutional neural network(CNN)properties to the support vector machine(SVM)for the auto-segmented brain tumor *** CNN model is initially used to detect brain tumors,while SVM is integrated to segment the tumor region *** proposed method was evaluated on a publicly available BraTS2020 *** statistical parameters used in this work for the mathematical measures are precision,accuracy,specificity,sensitivity,and dice ***,our method achieved an accuracy value of 0.98,which is most prominent than existing ***,the proposed approach is more suitable for medical experts to diagnose the early stages of the brain tumor.

关键词： Brain tumor support vector machine convolutional neural network BraTS classification

Urban constructed wetlands: Assessing ecosystem services and disservices for safe, resilient, and sustainable cities

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Frontiers of Engineering Management 2023年第4期10卷 582-596页

作者： aamir Mehmood SHAH Gengyuan LIU Yu CHEN Qing YANG Ningyu YAN Feni AGOSTINHO Cecilia MVBALMEIDA Biagio FGIANNETTI State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentBeijing Normal UniversityBeijing 100875China Beijing Engineering Research Center for Watershed Environmental Restoration&Integrated Ecological Regulation Beijing 100875China Advanced Interdisciplinary Institute of Environment and Ecology Beijing Normal UniversityZhuhai 519087China Key Laboratory for City Environmental Safety and Green Development of the Ministry of Education Institute of Environmental and Ecological EngineeringGuangdong University of TechnologyGuangzhou510006China Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou511458China State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentBeijing Normal UniversityBeijing100875China Programa de Pós-graduação em Engenharia de Produção Laboratório de Produção e Meio AmbienteUniversidade Paulista(UNIP)São Paulo04026-002Brazil

Climate change and rapid urbanization are pressing environmental and social concerns, with approximately 56% of the global population living in urban areas. This number is expected to rise to 68% by 2050, leading to the expansion of cities and encroachment upon natural areas, including wetlands, causing their degradation and fragmentation. To mitigate these challenges, green and blue infrastructures (GBIs), such as constructed wetlands, have been proposed to emulate and replace the functions of natural wetlands. This study evaluates the potential of eight constructed wetlands near Beijing, China, focusing on their ecosystem services (ESs), cost savings related to human health, growing/maintenance expenses, and disservices using an emergy-based assessment procedure. The results indicate that all constructed wetlands effectively purify wastewater, reducing nutrient concentrations (e.g., total nitrogen, total phosphorus, and total suspended solids). Among the studied wetlands, the integrated vertical subsurface flow constructed wetland (CW-4) demonstrates the highest wastewater purification capability (1.63E+14 sej/m^(2)/yr) compared to other types (6.78E+13 and 2.08E+13 sej/m^(2)/yr). Additionally, constructed wetlands contribute to flood mitigation, groundwater recharge, wildlife habitat protection, and carbon sequestration, resembling the functions of natural wetlands. However, the implementation of constructed wetlands in cities is not without challenges, including greenhouse gas emissions, green waste management, mosquito issues, and disturbances in the surrounding urban areas, negatively impacting residents. The ternary phase diagram reveals that all constructed wetlands provide more benefits than costs and impacts. CW-4 shows the highest benefit-cost ratio, reaching 50%, while free water surface constructed wetland (CW-3) exhibits the lowest benefits (approximately 38%), higher impacts (approximately 25%), and lower costs (approximately 37%) compared to other we

关键词： constructed wetland emergy ecosystem services disservices ternary diagram

Structural Analysis of the SARS-CoV-2 Omicron Variant Proteins

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Research 2021年第2期2021卷 759-762页

作者： Qiangzhen Yang Ali Alamdar Shah Syed aamir Fahira Yongyong Shi Bio-X Institutes Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders(Ministry of Education)Shanghai Jiao Tong University1954 Huashan RoadShanghai 200030China Biomedical Sciences Institute of Qingdao University(Qingdao Branch of SJTU Bio-X Institutes) Qingdao UniversityQingdao 266003China Shanghai Key Laboratory of Psychotic Disorders Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghai 200030China Shanghai Key Laboratory of Sleep Disordered Breathing Shanghai Jiao Tong University Affiliated Sixth People’s HospitalShanghaiChina The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052China Department of Psychiatry First Teaching Hospital of Xinjiang Medical UniversityUrumqi830046China

The spread of the latest SARS-CoV-2 variant Omicron is particularly concerning because of the large number of mutations present in its genome and lack of knowledge about how these mutations would affect the current SARS-CoV-2 vaccines and ***,by performing phylogenetic analysis using the Omicron spike(S)protein sequence,we found that the Omicron S protein presented the longest evolutionary distance in relation to the other SARS-CoV-2 *** predicted the structures of S,M,and N proteins of the Omicron variant using AlphaFold2 and investigated how the mutations have affected the S protein and its parts,S1 NTD and RBD,in *** found many amino acids on RBD were mutated,which may influence the interactions between the RBD and ACE2,while also showing the S309 antibody could still be capable of neutralizing Omicron *** Omicron S1 NTD structures display significant differences from the original strain,which could lead to reduced recognition by antibodies resulting in potential immune escape and decreased effectiveness of the existing ***,this study of the Omicron variant was mainly limited to structural predictions,and these findings should be explored and verified by subsequent *** study provided basic data of the Omicron protein structures that lay the groundwork for future studies related to the SARS-CoV-2 Omicron variant.

关键词： concerning subsequent neutral

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低公交占有率地区需求响应公交选择意愿研究——以巴基斯坦卡拉奇市为例

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低公交占有率地区需求响应公交选择意愿研究——以巴基斯坦卡拉奇...

作者： aamir Hussain 大连理工大学

学位级别：硕士

需求响应公交(DRT)具有可变路线和灵活时间表,作为常规公交有效补充,近年来得到广泛应用。本文试图研究巴基斯坦卡拉奇市在当前公交占有率较低的情况下,分析引入DRT的可行性。通过设计行为选择实验对该市居民进行(SP)偏好调查,建立多项L... 详细信息

需求响应公交(DRT)具有可变路线和灵活时间表,作为常规公交有效补充,近年来得到广泛应用。本文试图研究巴基斯坦卡拉奇市在当前公交占有率较低的情况下,分析引入DRT的可行性。通过设计行为选择实验对该市居民进行(SP)偏好调查,建立多项Logit模型解析其影响因素。结果显示,现有常规公交使用者转移使用需求响应公交的意愿较低,非日常公交使用者有较高意愿使用DRT服务。等待时间和取消费用的影响较为有限,因此很难通过减少等待时间、降低取消费用等方法来显著提高DRT竞争力。

关键词：需求响应公交 SP调查行为选择实验离散选择模型

Meta-Analysis on the associations between Prenatal Perfluoroalkyl Substances Exposure and Adverse Birth Outcomes

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Journal of Donghua University(English Edition) 2021年第2期38卷 158-180页

作者： LI Fang ZHONG Zhehui XU Chenye ZHANG Beibei MUHAMMAD aamir SHEN Chensi LIU Shuren YIN Shanshan College of Environmental Science and Engineering Donghua UniversityShanghai 201620China Water-Energy Resilience Research Laboratory School of EngineeringWestlake UniversityHangzhou 310024China College of Environmental and Resource Sciences Zhejiang UniversityHangzhou 310058China Interdisciplinary Research Academy(IRA) Zhejiang Shuren UniversityHangzhou310015China

The epidemiological associations between the prenatal perfluoroalkyl substances(PFASs)exposure and the reproductive outcomes remain controversial.A continuous evaluation is needed to combine the inconsistent *** this study,we explored the associations between PFASs exposure and the low birth weight(LBW),preterm birth and small for gestational age(SGA).The quality of selected literature,quantitative estimates,publication bias and subgroup analysis were performed on the basis of 17 retrieved articles published before December *** results showed a significant positive association between the perfluorooctane sulfonate(PFOS)exposure and the risk of LBW[Odds ratio(OR)=1.17;95%confidence interval(CI):1.01,1.36;heterogeneity:P=0.30,I2=17%].The positive association was also observed between the PFOS and the risk of preterm birth(OR=1.19;95%CI:1.01,1.39,P=0.007;I2=62%).There was a paucity of evidence regarding the negative effects of perfluorooctanoic acid(PFOA),perfluorohexanesulfonic acid(PFHxS)and perfluorononanoic acid(PFNA)on the pregnancy *** findings from the subgroup analysis(the sampling period,the birth gender and biologic specimens)did not substantially altered the results of the overall pooled estimate *** increased prevalence of negative birth outcomes with gestational PFASs exposure warrants further explorations from biological process perspective.

关键词： perfluoroalkyl substances(PFASs) meta-analysis low birth weight(LBW) small for gestational age(SGA) preterm birth

Estimation of infiltration models parameters and their comparison to simulate the onsite soil infiltration characteristics

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International Journal of Agricultural and Biological Engineering 2019年第3期12卷 84-91页

作者： Hafiz Umar Farid Zahid Mahmood-Khan Ijaz Ahmad aamir Shakoor Muhammad Naveed Anjum Muhammad Mazhar Iqbal Muhammad Mubeen Muhammad Asghar Department of Agricultural Engineering Bahauddin Zakariya UniversityMultan-Pakistan Center of Excellence in Water Resources Engineering(CEWRE) University of Engineering and TechnologyLahore-Pakistan Division of Hydrology Water-Land Resources in Cold and Arid Regions Cold and Arid Region Environmental and Engineering InstituteChinese Academy of SciencesLanzhou 730000China Graduate School of Water Resources Sungkyunkwan UniversitySuwon-si 2066Korea Department of Environmental Sciences COMSATS Institute of Information TechnologyVehari-Pakistan

Detailed knowledge about soil characteristics and site-specific final steady infiltration rate could help to increase the irrigation water use efficiency and decrease water losses in agricultural *** experiments were conducted on Agricultural Research Farm of Bahauddin Zakariya University,Multan,Pakistan during *** cumulative infiltration depth was measured using double ring infiltrometer at selected six points of the study *** commonly used infiltration models such as Kostikov’s,Philip’s and Horton’s were fitted to the field infiltration data for determination of model parameters and to find the best fit model for the study ***’s infiltration model’s parameters such as empirical constant‘c’and infiltration decay constants‘k’were obtained in the ranges of 0.140-0.290 and 0.307-0.433,***’s infiltration model’s parameters such as sorptivity‘S’and conductivity constant‘A’were found in the ranges of 0.167-0.288 cm/min1/2 and-0.001 to-0.009 cm/min,***,the Horton’s model’s‘parameter‘k’was obtained in the range of-1.619 *** value of infiltration capacity at onset of infiltration(fo)was obtained as 1.744 to 3.491 for all the six *** analysis showed that the infiltration models using the estimated parameters have satisfactory prediction capability at all the selected ***’s model provided the lowest mean values for RMSE(0.235)and highest mean values for ME(94%);and the lowest mean values for MPD(0.127).This indicated that infiltration can be well-described by the Horton’s model at the selected site.

关键词： infiltration characteristics infiltration models parameters estimation perdition capability