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Dengue outbreak in Swat and Mansehra,Pakistan 2013;an epidemiological and diagnostic perspective

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Asian Pacific Journal of Tropical Medicine 2016年第4期9卷 371-375页

作者： Muhammad Suleman Rani Faryal uzma bashir aamir Muhammad Masroor Alam Nadia Nisar Salmaan Sharif Shahzad Shaukat Adnan Khurshid Mehar Angez Massab Umair Ghulam Mujtaba Mian Muhammad Sufian Yasir Arshad Lubna Rehman Syed Sohail Zahoor Zaidi Department of Microbiology.Quaid-i-Azam University Department of Virology National Institute of Health

Objective:To High light some epidemiological,clinical and diagnostic features of dengue fever during an outbreak and the role of different diagnostic techniques to achieve the highest level of accuracy in ***:Blood samples(n=323) were collected along with epidemiological and clinical data from suspected dengue patients who visited different hospitals in Swat and Mansehra district of Pakistan between May-November 2013 during a dengue *** were tested for the detection of viral nucleic acid by real-lime *** structural protein-1(NS1antigen and IgM antibodies by ***:Out of 323 cases with clinical dengue infection,304 were positive by one or more diagnostic parameter:201 samples were positive by real-time PCR,209 were positive by NS1 ELISA and 190 were positive by IgM *** of real-time PCR and NS1 *** were comparable for early diagnosis of dengue virus *** antibody detection assay was found useful for the diagnosis in the samples collected later than day 5 of ***:The use of real-lime PCR or detection of non stnictural protein NS 1 by ELISA followed by IgM antibodies detection can be recommended for early diagnosis of dengue virus infection with a high level of accuracy.

关键词： Dengue virus NS1 Antigen Pakistan Diagnosis Epidemiology Khyber Pakhtunkhwa

Preliminary Seroepidemiological survey of dengue infections in Pakistan,2009-2014

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Infectious Diseases of Poverty 2017年第1期6卷 428-434页

作者： Muhammad Suleman Hyeong-Woo Lee Syed Sohail Zahoor Zaidi Muhammad Masroor Alam Nadia Nisar uzma bashir aamir Salmaan Sharif Shahzad Shaukat Adnan Khurshid Mehar Angez Massab Umair Ghulam Mujtaba Rani Faryal Department of Microbiology Quaid-i-Azam UniversityIslamabadPakistan Department of Virology National Institute of HealthIslamabadPakistan Department of Tropical Medicine and Parasitology Inha University School of MedicineIncheon 22212Republic of Korea

Background:Dengue virus is the causative agent of dengue fever,a vector borne infection which causes selflimiting to life threatening disease in humans.A sero-epidemiological study was conducted to understand the current epidemiology of dengue virus in Pakistan which is now known as a dengue endemic country after its first reported outbreak in ***:To investigate the prevalence of dengue virus in Pakistan during 2009-2014,a total of 9,493 blood samples were screened for the detection of anti-dengue IgM antibodies using *** and demographic features available with hospital records were reviewed to ascertain mortalities related to dengue hemorrhagic shock ***:Out of 9,493 samples tested,37%(3,504)were found positive for anti-dengue IgM *** the seropositive cases,73.6%(2,578/3,504)were male and 26.4%(926/3,504)were *** highest number(382/929;41.1%)of sero-positive cases was observed among the individuals of age group 31-40 *** highest number of symptomatic cases was reported in October(46%;4,400/9,493),and the highest number of sero-positive cases among symptomatic cases was observed in November(45.7%;806/1,764).Mean annual patient incidence(MAPI)during 2009-2014 in Pakistan remained 0.30 with the highest annual patient incidence(11.03)found in *** to the available medical case record,472 dengue related deaths were reported during ***:The data from earlier reports in Pakistan described the dengue virus incidence from limited areas of the *** findings are important considering the testing of clinical samples at a larger scale covering patients of vast geographical regions and warrants timely implementation of dengue vector surveillance and control *** registration number:It is an epidemiological research study,so trial registration is not required.

关键词： Dengue Virus epidemiology Pakistan IgM ELISA Vector

An Implementation of Multiscale Line Detection and Mathematical Morphology for Efficient and Precise Blood Vessel Segmentation in Fundus Images

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Computers, Materials & Continua 2024年第5期79卷 2565-2583页

作者： Syed Ayaz Ali Shah aamir Shahzad Musaed Alhussein Chuan Meng Goh Khursheed Aurangzeb Tong Boon Tang Muhammad Awais Department of Electrical and Computer Engineering COMSATS University IslamabadAbbottabad CampusAbbottabad22060Pakistan Department of Computer Engineering College of Computer and Information SciencesKing Saud UniversityP.O.Box 51178Riyadh11543Saudi Arabia Faculty of Information and Communication Technology University Tunku Abdul RehmanKampar CampusKampar31900Malaysia Centre for Intelligent Signal and Imaging Research University Teknologi PETRONASBandar Seri IskandarPerak32610Malaysia School of Computing Sciences University of East AngliaNorwichNR47TJUK

Diagnosing various diseases such as glaucoma,age-related macular degeneration,cardiovascular conditions,and diabetic retinopathy involves segmenting retinal blood *** task is particularly challenging when dealing with color fundus images due to issues like non-uniformillumination,low contrast,and variations in vessel appearance,especially in the presence of different ***,the speed of the retinal vessel segmentation system is of utmost *** the surge of now available big data,the speed of the algorithm becomes increasingly important,carrying almost equivalent weightage to the accuracy of the *** address these challenges,we present a novel approach for retinal vessel segmentation,leveraging efficient and robust techniques based on multiscale line detection and mathematical *** algorithm’s performance is evaluated on two publicly available datasets,namely the Digital Retinal Images for Vessel Extraction dataset(DRIVE)and the Structure Analysis of Retina(STARE)*** experimental results demonstrate the effectiveness of our method,withmean accuracy values of 0.9467 forDRIVE and 0.9535 for STARE datasets,aswell as sensitivity values of 0.6952 forDRIVE and 0.6809 for STARE ***,our algorithmexhibits competitive performance with state-of-the-art ***,it operates at an average speed of 3.73 s per image for DRIVE and 3.75 s for STARE *** is worth noting that these results were achieved using Matlab scripts containing multiple *** suggests that the processing time can be further reduced by replacing loops with *** the proposed algorithm can be deployed in real time *** summary,our proposed system strikes a fine balance between swift computation and accuracy that is on par with the best available methods in the field.

关键词： Line detector vessel detection localization mathematical morphology image processing

A two-branch multiscale spectral-spatial feature extraction network for hyperspectral image classification

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Journal of Information and Intelligence 2024年第3期2卷 224-235页

作者： aamir Ali Caihong Mu Zeyu Zhang Jian Zhu Yi Liu Key Laboratory of Intelligent Perception and Image Understanding of Ministry of Education Collaborative Innovation Center of Quantum Information of Shaanxi ProvinceSchool of Artificial IntelligenceXidian UniversityXi'an 710071China school of Electronic Engineering Xidian UniversityXi'an 710071China

In the field of hyperspectral image(HSI)classification in remote sensing,the combination of spectral and spatial features has gained considerable *** addition,the multiscale feature extraction approach is very effective at improving the classification accuracy for HSIs,capable of capturing a large amount of intrinsic ***,some existing methods for extracting spectral and spatial features can only generate low-level features and consider limited scales,leading to low classification results,and dense-connection based methods enhance the feature propagation at the cost of high model *** paper presents a two-branch multiscale spectral-spatial feature extraction network(TBMSSN)for HSI *** design the mul-tiscale spectral feature extraction(MSEFE)and multiscale spatial feature extraction(MSAFE)modules to improve the feature representation,and a spatial attention mechanism is applied in the MSAFE module to reduce redundant information and enhance the representation of spatial fea-tures at *** we densely connect series of MSEFE or MSAFE modules respectively in a two-branch framework to balance efficiency and effectiveness,alleviate the vanishing-gradient problem and strengthen the feature *** evaluate the effectiveness of the proposed method,the experimental results were carried out on bench mark HsI datasets,demonstrating that TBMSSN obtained higher classification accuracy compared with several state-of-the-art methods.

关键词： Hyperspectral image classification Multiscale spectral-spatial information Two-branch architecture

Multifunctional MXene/Carbon Nanotube Janus Film for Electromagnetic Shielding and Infrared Shielding/Detection in Harsh Environments

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Nano-Micro Letters 2024年第10期16卷 543-560页

作者： Tufail Hassan aamir Iqbal Byungkwon Yoo Jun Young Jo Nilufer Cakmakci Shabbir Madad Naqvi Hyerim Kim Sungmin Jung Noushad Hussain Ujala Zafar Soo Yeong Cho Seunghwan Jeong Jaewoo Kim Jung Min Oh Sangwoon Park Youngjin Jeong Chong Min Koo School of Advanced Materials Science and Engineering Sungkyunkwan UniversitySeobu-ro 2066Jangan-guSuwon-siGyeonggi-do 16419Republic of Korea Department of Materials Science and Engineering Soongsil UniversitySeoul 06978Republic of Korea Institute of Advanced Composite Materials Korea Institute of Science and Technology92 Chudong-roBongdong-eupWanju-gunJeollabuk-do 55324Republic of Korea R&D Center INNOMXENE Co. Ltd.Daejeon 34365Republic of Korea School of Chemical Engineering Sungkyunkwan UniversitySeobu-ro 2066Jangan-guSuwon-siGyeonggi-do 16419Republic of Korea

Multifunctional,flexible,and robust thin films capable of operating in demanding harsh temperature environments are crucial for various cutting-edge *** study presents a multifunctional Janus film integrating highly-crystalline Ti_(3)C_(2)T_(x) MXene and mechanically-robust carbon nanotube(CNT)film through strong hydrogen *** hybrid film not only exhibits high electrical conductivity(4250 S cm^(-1)),but also demonstrates robust mechanical strength and durability in both extremely low and high temperature environments,showing exceptional resistance to thermal *** hybrid Janus film of 15μm thickness reveals remarkable multifunctionality,including efficient electromagnetic shielding effectiveness of 72 dB in X band frequency range,excellent infrared(IR)shielding capability with an average emissivity of 0.09(a minimal value of 0.02),superior thermal camouflage performance over a wide temperature range(−1 to 300℃)achieving a notable reduction in the radiated temperature by 243℃ against a background temperature of 300℃,and outstanding IR detection capability characterized by a 44%increase in resistance when exposed to 250 W IR *** multifunctional MXene/CNT Janus film offers a feasible solution for electromagnetic shielding and IR shielding/detection under challenging conditions.

关键词： MXene/carbon nanotube Janus film Electromagnetic interference shielding Infrared shielding Thermal camouflage Infrared detection

Left bundle branch pacing vs biventricular pacing in heart failure patients with left bundle branch block:A systematic review and meta-analysis

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World Journal of Cardiology 2024年第1期16卷 40-48页

作者： Farah Yasmin Abdul Moeed Rohan Kumar Ochani Hamna Raheel Malik Ali Ehtsham Awan Ayesha Liaquat Arisha Saleem Muhammad aamir Nael Hawwa Salim Surani Department of Internal Medicine Yale University School of MedicineNew HavenCT 06511United States Department of Medicine Dow University of Health ScienceKarachi 74200SindhPakistan Department of Medicine SUNNY Upstate Medical UniversitySyracuseNY 13210United States Department of Cardiovascular Medicine Lehigh Valley Heart and Vascular InstituteAllentownPA 18105United States Department of Medicine Cleveland ClinicClevelandOH 44195United States Department of Medicine&Pharmacology Texas A&M UniversityCollege StationTX 77843United States

BACKGROUND Left bundle branch pacing(LBBP)is a novel pacing modality of cardiac resynchronization therapy(CRT)that achieves more physiologic native ventricular activation than biventricular pacing(BiVP).AIM To explore the validity of electromechanical resynchronization,clinical and echocardiographic response of *** Systematic review and Meta-analysis were conducted in accordance with the standard guidelines as mentioned in detail in the methodology *** In our analysis,the success rate of LBBP-CRT was determined to be 91.1%.LBBP CRT significantly shortened QRS duration,with significant improvement in echocardiographic parameters,including left ventricular ejection fraction,left ventricular end-diastolic diameter and left ventricular end-systolic diameter in comparison with *** A significant reduction in New York Heart Association class and B-type natriuretic peptide levels was also observed in the LBBP-CRT group vs BiVP-CRT ***,the LBBP-CRT cohort had a reduced pacing threshold at follow-up as compared to BiVP-CRT.

关键词： Left bundle branch pacing Biventricular pacing QRS duration Left ventricular ejection fraction Heart failure

Efficacy and safety of pharmacotherapeutic interventions used in visceral leishmaniasis clinical trials:A systematic review and network meta-analysis

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Asian Pacific Journal of Tropical Medicine 2022年第8期15卷 343-353,I0001-I0010页

作者： aamir bashir Gautam Sahu Ishfaq Rashid Pramil Tiwari Department of Pharmacy Practice National Institute of Pharmaceutical Education and ResearchS.A.S.Nagar Mohali160062PunjabIndia

Objective:To compare the efficacy and safety outcomes of different antileishmanial agents used in visceral leishmaniasis clinical ***:A systematic literature search in PubMed/MEDLINE,EMBASE,Cochrane,and Google Scholar was done using keywords“randomized controlled trials”,“antileishmanial”and“visceral leishmaniasis”.The outcomes included were cure rate,overall withdrawals,relapse rate,and treatment-emergent adverse *** estimates through the frequentist network meta-analysis approach were presented as OR with 95%*** plots were used for identifying the“best intervention”based on p-scores obtained using the surface under the cumulative *** risk of bias was evaluated by using Pedro ***:Seventeen randomized controlled trials with 5143 visceral leishmaniasis patients who received different antileishmanial agents(amphotericin B,miltefosine,paromomycin,meglumine antimoniate,sodium stibogluconate,sitamaquine,and pentavalent antimonials)and met the inclusion criteria were *** efficacy outcomes of the treatments,the rankogram of the network meta-analysis revealed that paromomycin(p-score=0.8148)has the highest probability of being best in the pool,followed by sodium stibogluconate(OR 0.82,95%CI 0.24-2.79,p-score=0.7580),amphotericin B+miltefosine(OR 0.66,95%CI 0.02-19.04,p-score=0.7329)as compared to the remaining treatments;however,the most of the treatment-emergent adverse events were reported with ***:Paromomycin reported the highest cure rates,while the maximum treatment-emergent adverse events were seen with sitamaquine.

关键词： Visceral leishmaniasis Treatment Efficacy Safety Network meta-analysis

考虑防洪风险的混凝土坝变形双控指标拟定方法研究

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水电能源科学 2024年第6期42卷 171-174,147页

作者：崔卫天黄耀英方卫华方晨 aamir HAMEED 三峡大学水利与环境学院湖北宜昌443002 水利部南京水利水文自动化研究所江苏南京210000

针对基于典型小概率法拟定大坝监控指标时的失效概率取值偏经验性以及目前变形监控指标未考虑变形变化速率的问题,将大坝变形失效风险与大坝防洪风险(上游来水和泄洪能力)相结合,将失效概率取设计防洪风险,采用典型小概率法拟定了关键... 详细信息

针对基于典型小概率法拟定大坝监控指标时的失效概率取值偏经验性以及目前变形监控指标未考虑变形变化速率的问题,将大坝变形失效风险与大坝防洪风险(上游来水和泄洪能力)相结合,将失效概率取设计防洪风险,采用典型小概率法拟定了关键测点变形监控指标,再基于设计洪水调洪演算库水位及其对应的变形分量变化速率,从而确定变形速率监控指标,提出了考虑防洪风险的混凝土坝变形和变形速率双监控指标的拟定方法。以某服役期高拱坝为例,拟定了典型测点实测变形和变形速率双监控指标,实测变形数据及其变化速率均小于拟定的变形监控指标和变形速率监控指标,这表明该大坝当前变形性态安全可控。

关键词：混凝土坝变形双控指标调洪演算小概率法

宫腔镜联合CD138及子宫内膜微生态检测对慢性子宫内膜炎的诊断价值

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河南外科学杂志 2024年第2期30卷 20-23页

作者： Mahmood aamir 张洁谭丽郑州大学第二附属医院生殖医学部郑州450014

目的探讨宫腔镜联合白细胞分化抗原138(CD138)及子宫内膜微生态检测对慢性子宫内膜炎(CE)的诊断价值。方法纳入2020-06—2023-05郑州大学第二附属医院生殖医学部收治的行体外受精-胚胎移植(IVF-ET)失败的541例患者,A组(101例)行宫腔镜联... 详细信息

目的探讨宫腔镜联合白细胞分化抗原138(CD138)及子宫内膜微生态检测对慢性子宫内膜炎(CE)的诊断价值。方法纳入2020-06—2023-05郑州大学第二附属医院生殖医学部收治的行体外受精-胚胎移植(IVF-ET)失败的541例患者,A组(101例)行宫腔镜联合CD138及子宫内膜微生物组群检查,B组(240例)行宫腔镜联合CD138,C组(200例)行宫腔镜检查。分析三种检查方法对CE的诊断价值。结果A组、B组、C组CE的检出率分别为74.26%、62.50%、51.50%,差异有统计学意义(P<0.05)。C组宫腔镜的漏诊率为16.67%,B组的漏诊率为9.90%。三联诊断的准确率高于三者单独诊断与二联诊断(P<0.05)。结论宫腔镜联合CD138与子宫内膜微生物组群检测,能提高IVF-ET失败患者的CE检出率,降低漏诊率,并指导临床精准治疗。

关键词：体外受精-胚胎移植宫腔镜白细胞分化抗原138 子宫内膜微生物组群