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Gut-liver axis improves with meloxicam treatment after cirrhotic liver resection

World Journal of Gastroenterology 2014年第40期20卷 14841-14854页

作者： Astrit R Hamza Avdyl S Krasniqi Pramod Kadaba Srinivasan Mamdouh Afify Christian Bleilevens uwe klinge René H Tolba Institute for Laboratory Animal Science and Experimental Surgery University Hospital Rheinisch-Westf?lische Technische Hochschule Aachen 52074 Aachen Germany Department of AbdominalSurgery University Clinical Center of Kosova Prishtina 10000Kosovo Department of Anesthesiology University Hospital Rheinisch-Westf?lische Technische Hochschule Aachen 52074 Aachen Germany Department of Surgery University Hospital Rheinisch-Westf?lische Technische Hochschule Aachen 52074 Aachen Germany

AIM: To investigate the effect of meloxicam on the gut-liver axis after cirrhotic liver resection.

关键词： Liver cirrhosis Liver resection Gut-liver axis Meloxicam Cyclooxigenase-2 Microcirculation

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Mesh implants: An overview of crucial mesh parameters

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World Journal of Gastrointestinal Surgery 2015年第10期7卷 226-236页

作者： Lei-Ming Zhu Philipp Schuster uwe klinge Department of Surgery Tongren Hospital School of MedicineShanghai Jiaotong University FEG Textiltechnik mbH Department for General Visceral and Transplant Surgery the University Hospital of the RWTH Aachen

Hernia repair is one of the most frequently performed surgical interventions that use mesh implants. This article evaluates crucial mesh parameters to facilitate selection of the most appropriate mesh implant, considering raw materials, mesh composition, structure parameters and mechanical parameters. A literature review was performed using the Pub Med database. The most important mesh parameters in the selection of a mesh implant are the raw material, structural parameters and mechanical parameters, which should match the physiological conditions. The structural parameters, especially the porosity, are the most important predictors of the biocompatibility performance of synthetic meshes. Meshes with large pores exhibit less inflammatory infiltrate, connective tissue and scar bridging, which allows increased soft tissue ingrowth. The raw material and combination of raw materials of the used mesh, including potential coatings and textile design, strongly impact the inflammatory reaction to the mesh. Synthetic meshes made from innovative polymers combined with surface coating have been demonstrated to exhibit advantageous behavior in specialized fields. Monofilament, largepore synthetic meshes exhibit advantages. The value of mesh classification based on mesh weight seems to be overestimated. Mechanical properties of meshes, such as anisotropy/isotropy, elasticity and tensile strength, are crucial parameters for predicting mesh performance after implantation.

关键词： Hernia repair Hernia mesh Incontinence mesh implan

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