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Helicobacter pylori:High dose amoxicillin does not improve primary or secondary eradication rates in an Irish cohort

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World Journal of Clinical Cases 2024年第16期12卷 2773-2779页

作者： Conor Costigan Aoife M O'Sullivan Jim O'Connell Shreyashee sengupta Thomas Butler Stephen Molloy Fintan John O'Hara Barbara Ryan Niall Breslin Sarah O'Donnell Anthony O'Connor Sinead Smith Deirdre McNamara Trinity Academic Gastroenterology Group School of Medicine-Trinity College DublinDublin D2Ireland Department of Gastroenterology Tallaght University HospitalDublin D24 NR0AIreland

BACKGROUND Helicobacter pylori(***)eradication rates have fallen globally,likely in large part due to increasing antibiotic resistance to traditional *** areas of high clarithromycin and metronidazole resistance such as ours,Maastricht VI guidelines suggest high dose amoxicillin dual therapy(HDADT)can be considered,subject to evidence for local *** this study we assess efficacy of HDADT therapy for *** eradication in an Irish *** To assess the efficacy of HDADT therapy for *** eradication in an Irish cohort as both first line,and subsequent therapy for patients diagnosed with *** All patients testing positive for *** in a tertiary centre were treated prospectively with HDADT(amoxicillin 1 g tid and esomeprazole 40 mg bid×14 d)over a period of 8 *** was confirmed with Urea Breath Test at least 4 wk after cessation of therapy.A delta-over-baseline>4%was considered *** demographics and treatment outcomes were recorded,analysed and controlled for basic demographics and prior *** *** One hundred and ninety-eight patients were identified with *** infection,10 patients were excluded due to penicillin allergy and 38 patients refused follow up *** all 139 were included in the analysis,55%(n=76)were female,mean age was 46.6 ***,93(67%)of patients were treatment-naïve and 46(33%)had received at least one previous course of *** groups were statistically ***-reported compliance with HDADT was 97%,mild side-effects occurred in 7%.There were no serious adverse drug *** the eradication rate for our cohort was 56%(78/139).Eradication rates were worse for those with previous treatment[43%(20/46)vs 62%(58/93),P=0.0458,odds ratio=2.15].Age and Gender had no effect on eradication *** Overall eradication rates with HDADT were *** being a simple and possibly better tolerated regime,these results do not

关键词： Helicobacter pylori eradication Helicobacter pylori High dose amoxicillin High dose amoxicillin dual therapy Triple therapy

Behavior of braced excavation in sand under a seismic condition: experimental and numerical studies

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Earthquake Engineering and Engineering Vibration 2018年第2期17卷 311-324页

作者： Sanku Konai Aniruddha sengupta Kousik Deb Department of Civil Engineering Indian Institute of Technology Kharagpur

The behavior of braced excavation in dry sand under a seismic condition is investigated in this paper.A series of shake table tests on a reduced scale model of a retaining wall with one level of bracing were conducted to study the effect of different design parameters such as excavation depth,acceleration amplitude and wall *** analyses using FLAC 2D were also performed considering one level of *** strut forces,lateral displacements and bending moments in the wall at the end of earthquake motion were compared with experimental *** study showed that in a post-seismic condition,when other factors were constant,lateral displacement,bending moment,strut forces and maximum ground surface displacement increased with excavation depth and the amplitude of base *** study also showed that as wall stiffness decreased,the lateral displacement of the wall and ground surface displacement increased,but the bending moment of the wall and strut forces *** net earth pressure behind the walls was influenced by excavation depth and the peak acceleration amplitude,but did not change significantly with wall *** force was the least affected parameter when compared with others under a seismic condition.

关键词： braced excavation shake table test seismic FLAC 2D displacement

A Delay-dependent Dynamic Wide Area Damping Controller for Renewable Energy Integrated Power System Resilient to Communication Failure

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CSEE Journal of Power and Energy Systems 2023年第2期9卷 577-588页

作者： Anirban sengupta Dushmanta Kumar Das Bidyadhar Subudhi Department of Electrical and Electronics Engineering Sikkim Manipal Institute of TechnologySMUSIkkim737136 India Department of Electrical and Electronics Engineering National Institute of TechnologyNagalandDimapur797103 India School of Electrical Science Indian Institute of TechnologyGoaIndia

Integration of renewable energy sources(RES)with a conventional power system has a detrimental effect on interarea *** popular RESs are solar photovoltaic(PV)and wind energy conversion systems(WECS).Both solar PV power generation and WECS are integrated with power systems using a power electronic *** the amount of RES generation lead towards reduction of system damping,which leads towards inter-area ***,the intermittent behavior of a RES reduces the effectiveness of damping controllers.A dynamic controller based wide area damping controller(WADC)is proposed in this paper to increase small signal stability of a RES integrated power *** WADC is designed for contemplating delay in a communication channel,communication failure and *** anti-windup compensator is developed to overcome the effect of actuator ***,the gain of the anti-windup compensator is calculated using LyapunovKrasovskii functional(LKF)in terms of linear matrix inequality(LMI).The actuator considered in this paper is a unified power flow controller(UPFC).Efficacy of PV and wind power integration on power system is also *** efficacy of the developed dynamic controller is verified using IEEE 39 bus and 68 bus power system.

关键词： Actuator saturation communication failure linear matrix inequality renewable energy sources time delay wide area damping control

The role of Pbx1 in T cells

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Protein & Cell 2011年第12期2卷 946-949页

作者： Mayami sengupta Laurence Morel Department of Pathology Immunology and Laboratory MedicineUniversity of FloridaGainesvilleFL 32610USA

Tissue and organ differentiation is tightly controlled to ensure proper development and function of the growing embryo as well as cells such as lymphocytes that differentiate throughout the adult *** it is vital that the genes and the protein they encode that are involved in these processes function ***,any mutation or error that occurs along the way can result in extensive damage,which is expressed in various ways in the embryo and can result in immune pathogenesis,including immunodeficiency and autoimmune diseases,when lymphocyte development is altered.

关键词： diseases lymphocytes pathogenesis

Provenance studies on the heavy mineral placers along the coastal deposits of Odisha,eastern India

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Journal of Palaeogeography 2022年第2期11卷 275-285页

作者： Shayantani Ghosal Sudha Agrahari Debashish sengupta Department of Geology and Geophysics Indian Institute of Technology KharagpurWest BengalIndia Department of Applied Geology Indian Institute of Technology(Indian School of Mines)DhanbadJharkhandIndia

The coastal deposits along the eastern part of the Indian Peninsula are known for the high abundance of heavy minerals. The present study, as discussed here, has been undertaken along the southwestern coastal part of Odisha, India, adjoining the charnockite-migmatite zone of the Eastern Ghat Mobile Belt(EGMB). The composition of the placers along the study area is primarily controlled by the detritus from the proximal hinterland rock type(s). The weathering index has been established based on the grain morphology, major element concentration and radioelement ratios. Petrological characteristics and grain morphology of monazite, zircon, ilmenite and rutile have been presented respectively, and their implications are discussed. The provenance study of these coastal placers is based on the abundance of rare earth elements(REE) and radioactive elements in the placer sands and the rock types in the study area. The tectonic implications are based on the major element abundance of the beach sands.

关键词： Monazite placers High background radiation area(HBRA) Eastern Ghat Mobile Belt(EGMB) Weathering Zircon Rare earth elements(REE) East coast of India

Silver recovery as Ag^0 nanoparticles from ion-exchange regenerant solution using electrolysis

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Journal of Environmental Sciences 2019年第4期31卷 161-173页

作者： Tabish Nawaz Sukalyan sengupta Chen-Lu Yang Civil and Environmental Engineering Department University of Massachusetts Dartmouth Center for Innovation and Entrepreneurship University of Massachusetts Dartmouth

Many silver(Ag)containing consumer-products(***)release Ag into the environment,posing ecotoxicological *** recovery mitigates environmental hazards,recycles Ag,and leads to *** the present work,Ag has been recovered as Ag^0nanoparticles from the spent solution(thiourea(TU)～0.5 mol/L pH～1.1–1.2,and Ag～550 mg/L)obtained from the regeneration of an Ag-loaded resin using a simple undivided electrolytic *** reclaimed regenerant solution has been recycled and reused in a closed-loop scheme over multiple *** process parameters,i.e.,current(0.05 A)and stirring speed(600 r/min),have been optimized for Ag recovery of～94%and TU loss of～2%.The reclaimed regenerant solution has been shown to regenerate Ag-loaded resin samples with>90%regeneration efficiency over 4 cycles of consecutive extraction and *** recovered Ag^0nanoparticles are monodisperse,consistently spherical in shape,and have a mean diameter of～6 nm with standard deviation of the Gaussian fit as～2.66 nm.

关键词： Silver recovery Ag^0 nanoparticles Waste management Thiourea Sustainability Resource recovery Electrowinning

Integrated Intelligent Electromagnetic Radiator Design for Future THz Communication:A Review

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Chinese Journal of Electronics 2022年第3期31卷 499-515页

作者： LU Xuyang Venkatesh Suresh Saeidi Hooman sengupta Kaushik UM-SJTU Joint Institute Shanghai Jiao Tong University Electrical and Computer Engineering Princeton University

Advances in 6 G communication changes how machines and humans interact. The blossom of new applications demands significantly higher data bandwidth while preserving the mobility and sustainability of electronic wireless communication systems. It also demands an integrable system that allows convenient interactions between communication units and signal processing units.A review of CMOS-based THz communication system solutions is presented, with a focus on novel systematic EM-circuit co-design philosophy. This review starts with a review of THz power generation, followed by the discussion of THz localization and THz beamforming for efficient high-throughput communication.

关键词： Terahertz Integrated circuits CMOS 6G MIMO

Reference tracking and transient response shaping of uncertain quasi one-sided Lipschitz nonlinear systems

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Journal of Control and Decision 2022年第2期9卷 165-174页

作者： Arunima Mukherjee Aparajita sengupta Indian Institute of Engineering Sciences and Technology ShibpurHowrahIndia

This work addresses the reference tracking problem for uncertain systems with quasi one-sided Lipschitz *** uncertainty is assumed to be of a norm bound parametric ***,transient response shaping using the concept of‘return time’is also *** controller design relies on the solution of Linear Matrix Inequalities(LMIs)and hence is compu-tationally *** proposed control law is linear in states,and thus the implementation is often *** illustrate the capability and simplicity of the proposed theory,three design examples are included.

关键词： Reference tracking norm bound parametric uncertainty return time linear matrix inequalities quasi one-sided Lipschitz nonlinearity

Synthesis of N-fused dithia and dibenzihomoporphyrins

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Organic Chemistry Frontiers 2022年第6期9卷 1580-1588页

作者： Rima sengupta Prosenjit Isar Mangalampalli Ravikanth Department of Chemistry Indian Institute of Technology BombayPowaiMumbai 400076India

N-Fused dithia and dibenzi homoporphyrins have been synthesized using a[2+2]approach by condensing one equivalent of appropriate dithienyl/di p-phenylene ethene diol with one equivalent of N-confused dipyrromethane in CH_(2)Cl_(2) under mild acid catalysed *** X-ray structure obtainedfor the N-fused dibenzi homoporphyrin revealed that the fused tripentacyclic ring was planar and wastilted by an angle of 11.35°whereas the p-phenylene moieties were highly deviated by angles of 48.70°and 50.93°from the mean plane defined by five meso carbon *** NMR and absorption featuressuggested the non-aromatic nature of both N-fused dithia and dibenzi *** DFT studiesrevealed that the N-fused dithia homoporphyrin was highly distorted with one thiophene ring facingoutside the macrocyclic *** spectral features of both N-fused dithia and dibenzi homoporphyrinswere supported by TD-DFT studies.

关键词： conditions cavity fused