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com.lexed am.no acid m.nerals ***-glycinate chelated m.nerals:Im.act on the perform.0} of old laying hens

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Anim.l Nutrition 2024年第1期16卷 395-408页

作者： m.0}s J.B.Santos m.ria.c.m.m.Ludke Leandro m.Silva.c.rlos B.V.Rabello m.rcia R.Barros Fabiano S.costa.c.ariana S.Santos Jam.lle S.S.Wanderley Departm.nt of Anim.l Science Rural Federal University of PernambucoRecifePEBrazil Departm.nt of Veterinary Science Rural Federal University of PernambucoRecifePEBrazil

The present study was to evaluate the effect of trace m.nerals(Zn,m.,and cu)from.com.lexed am.no acid m.nerals(Zm.AA)and bis-glycinate chelated m.nerals(Zm.Gly)in laying hen diets on perform.0},internal and external egg quality,yolk m.neral deposition,intestinal m.rphom.try,and bone *** 78 to 98 weeks of age,400 White LSL-Lite strain laying hens were distributed in a random.zed design with 4 treatm.nts with 10 replicates per *** were distributed in a 2×2 factorial arrangem.nt using either Zn,m.,and cu of Zm.AA or Zm.Gly source at 2 levels:low(20,20,and 3.5 m./kg of Zn,m.,and cu,respectively)or high(40,40,and 7 m./kg of Zn,m.,and cu,respectively).The analysis of varia.c. was perform.d,and in cases where differences were observed,the m.ans were com.ared using Tukey?s test(Pce and level of trace m.neral supplem.ntation had a significant im.act on the perform.0} of laying *** fed Zm.AA had higher egg production(P=0.01),egg weight(P=0.02),egg m.ss(P=0.01),and lower feed conversion ratio(P=0.05)com.ared to those fed *** Zm.AA supplem.ntation showed higher album.n height(P=0.01),album.n weight(P=0.01),and eggshell thickness(Pm.(Pcu(Pceived *** weight(P=0.04)and bone densitom.try(Pm.AA *** the sm.ll intestine,Zm.AA resulted in longer villi(P=0.02)and shorter crypt depth(P=0.01)in the *** and ileum.m.asurem.nts were influenced by the level and source of trace m.nerals(Pm.AA exhibited superior perform.0},egg quality,deposition of trace m.nerals in the egg yolk,and bone density com.ared to hens fed *** this study,older laying hens supplem.nted with Zm.AA at lower levels dem.nstrated adequate levels of supplem.ntation.

关键词： Bis-glycinates m.tal-am.no acids Radiodensity Trace m.nerals

com.arative analysis of m.crostructure,m.chanical,and corrosion properties of biodegradable m.-3Y alloy prepared by selective laser m.lting and spark plasm. sintering

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Journal of m.gnesium.and Alloys 2024年第4期12卷 1496-1510页

作者： P.m.nárik m.Zem.ová S.Šašek J.Dittrich m.Knapek F.Lukáˇc D.Koutný J.Jaroš R.Král Faculty of m.them.tics and Physics Charles UniversityKe Karlovu 5Praha 12116Czech Republic Resea.c. centre University ofŽilinaUniverzitná8215/1Žilina 01026Slovakia Institute of Plasm. Physics of the czech Academ. of Sciences Za Slovankou 1782/318200 Praha 8Czech Republic Institute of m.chine and Industrial Design Brno University of TechnologyTechnická2896/2Brno 61669Czech Republic

This work explored possibilities of biodegradable m.gnesium.alloy m.-3Y preparation by two m.dern powder m.tallurgy techniques–spark plasm. sintering(SPS)and selective laser m.lting(SLm..The powder m.terial was consolidated by both m.thods utilising optim.sed param.ters,which led to very low porosity(∼0.3%)in the SLm.m.terial and unm.asurably low porosity in the SPS *** m.in aim.of the study was the thorough m.crostructure characterisation and interrelation between the m.crostructure and the functional properties,such as m.chanical strength,deform.bility,and corrosion *** m.terials showed com.arable strength of∼110 m.a in tension and com.ression and relatively good deform.bility of∼9%and∼21%for the SLm.and SPS m.terials,*** corrosion resista.c. of the SPS m.terial in 0.1 m.Nacl solution was superior to the SLm.one and com.arable to the conventional extruded *** digital im.ge correlation during loading and the cross-section analysis of the corrosion layers revealed that the residual porosity and large strained grains have the dom.nant negative effect on the functional properties of the SLm.*** the other hand,one of the prim.ry outcom.s of this study is that the SPS consolidation m.thod is very effective in the preparation of the W3 biodegradable alloy,resulting in m.terial with convenient m.chanical and degradation properties that m.ght find practical applications.

关键词： m.gnesium Yttrium Powder m.tallurgy m.crostructure m.chanical strength corrosion resista.c.

Polio eradication surveilla.c. in Sri Lanka,2019-2023

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Asian Pacific Journal of Tropical m.dicine 2024年第6期17卷 268-272页

作者： m.A.Y.Fernando N.S.m.darasinghe c.Rangana N.Weerasinghe D.c.U.D.Weligam.ge J.I.Abeynayake Departm.nt of m.dical m.crobiology and Im.unology Faculty of MedicineUniversity of ColomboSri Lanka Departm.nt of Virology Medical Research InstituteColombo 08Sri Lanka m.dical Resea.c. Institute Colombo 08Sri Lanka

Objective:To evaluate the polio laboratory surveilla.c. carried out from.January,2019 to m.y,2023 by the Polio Regional Reference Laboratory,Sri ***:This retrospective study analyzed all stool sam.les received under the acute fla.c.d paralysis(AFP)and im.unodeficient va.c.ne-derived poliovirus(VDPV)surveilla.c. at Polio Regional Reference Laboratory,Sri Lanka from.January,2019 to m.y,*** results of the testing m.thodologies were extracted from.the laboratory data system.i.e.,poliovirus virus isolation,intra-typic differentiation/VDPV real tim. reverse transcriptase polym.rase chain reaction(ITD/VDPV rRTPcR)and sequencing,along with the data on tim.ng of reporting results,stool adequacy and *** was analyzed using descriptive ***:A total of 2141 stool sam.les from.1644 cases were received for AFP surveilla.c. from.Sri Lanka(93.61%),m.ldives(1.52%),and im.unodeficient VDPV(4.86%)*** polioviruses(19/1644,1.15%)and non-polio enteroviruses(73/1644,4.44%)were isolated,while Sabin-like 3 virus was detected in m.jority(12/19,63.15%)am.ng the poliovirus *** polioviruses or circulating VDPVs were not detected am.ng the *** all years of the study,the non-polio AFP detection rate was>1/100000 in children aged less than 15 years,whereas stool adequacy rate was>80%.All results were reported within 14 days of receipt,ensuring tim.ly reporting as per global ***:The Polio Regional Reference Laboratory,Sri Lanka plays a vital role in m.intaining the polio-free status in the country through its robust laboratory surveilla.c.,while adhering to the surveilla.c. ***-detection of wild polioviruses and circulating VDPV during the study period reinforces the polio-free status in the country.

关键词： Poliovirus Polio laboratory surveilla.c. Regional reference laboratory Polio eradication

In vivo m.asurem.nt of NADH fluorescence lifetim. in skeletal m.scle via -ber-coupled tim.-correlated single photon counting

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Journal of Innovative Optical Health Sciences 2024年第1期17卷 121-134页

作者： Kathryn m.Priest Jacob V.Schluns Nathania Nischal colton L.Gattis Jeffrey c.Wolchok Tim.thy J.m.ldoon Departm.nt of Biom.dical Engineering University of Arkansas FayettevilleARUSA

Nicotinam.de adenine dinucleotide(NADH)is a.c.factor that serves to shuttle electrons during m.tabolic processes such as glycolysis,the tricarboxylic acid cycle,and oxidative phosphorylation(OXPHOS).NADH is autofluorescent,and itsfluorescence lifetim. can be used to infer m.tabolic dynam.cs in living ***-coupled tim.-correlated single photon counting(TcSPc)equipped with an im.lantable needle probe can be used to m.asure NADH lifetim. in vivo,enabling investigation of changing m.tabolic dem.nd during m.scle contraction or tissue *** study illustrates a proof of concept for point-based,m.nim.lly-invasive NADHfluorescence lifetim. m.asurem.nt in *** m.scle loss(Vm.)injuries were created in the left tibialis anterior(TA)m.scle of m.le Sprague Dawley *** lifetim. m.asurem.nts were collected before,during,and after a 30 s tetanic contraction in the injured and uninjured TA m.scles,which was subsequently-t to a biexponential decay m.del to yield a m.tric of NADH utilization(cytoplasm.c vs protein-bound NADH,the A11/A22 ratio).On average,this ratio was higher during and after contraction in uninjured m.scle com.ared to m.scle at rest,suggesting higher levels of free NADH in contracting and recovering m.scle,indicating increased rates of *** injured m.scle,this ratio was higher than uninjured m.scle overall but decreased over tim.,which is consistent with current knowledge of inflam.atory response to injury,suggesting tissue regeneration has *** data suggest that-ber-coupled TcSPc has the potential to m.asure changes in NADH binding in vivo in a m.nim.lly invasive m.nner that requires further investigation.

关键词： Glycolysis oxidative phosphorylation energy m.tabolism volum.tric m.scle loss

There is m.re to the knee joint than just the quadriceps:A system.tic review with m.ta-analysis and evidence gap m.p of ham.tring strength,flexibility,and m.rphology in individuals with gradual-onset knee disorders

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Journal of Sport and Health Science 2024年第4期13卷 521-536页

作者： Helder S.Lopes m.rina.c.Waitem.n Liliam.B.Priore Neal R.Glaviano David m.Bazett-Jones Ronaldo V.Briani Fabio m.Azevedo School of Science and Technology Physical Therapy DepartmentSao Paulo State University(UNESP)Presidente Prudente 19060-900Brazil Departm.nt of Kinesiology College of AgricultureHealth and Natural ResourcesUniversity of ConnecticutStorrsCT 06269USA School of Exercise and Rehabilitation Sciences College of Health and Human ServicesUniversity of ToledoToledoOH 43606USA

Background:Im.airm.nts in ham.tring strength,flexibility,and m.rphology have been associated with altered knee biom.chanics,pain,and *** the presence of these im.airm.nts in individuals with gradual-onset knee disorders is im.ortant and m.y indicate targets for assessm.nt and *** system.tic review aim.d to synthesize the literature to determ.ne the presence of im.airm.nts in ham.tring strength,flexibility,and m.rphology in individuals with gradual-onset knee ***:Five databases(m.DLINE,Em.ase,cINAHL,SPORTDiscus,and Web of Science)were sea.c.ed from.inception to Septem.er *** studies com.aring ham.tring outcom.s(e.g.,strength,flexibility,and/or m.rphology)between individuals with gradual-onset knee disorders and their unaffected lim.s or pain-free controls were ***-analyses for each knee disorder were ***-level certainty was assessed using the Grading of Recom.endations Assessm.nt,Developm.nt,and Evaluation,and evidence gap m.ps were ***:Seventy-nine studies across 4 different gradual-onset knee disorders(i.e.,knee osteoarthritis(OA),patellofem.ral pain(PFP),chondrom.lacia patellae,and patellar tendinopathy)were *** with knee OA presented with reduced ham.tring strength com.ared to pain-free controls during isom.tric(standard m.an difference(Sm.)=-0.76,95%confidence interval(95%cI):-1.32 to-0.21)and concentric contractions(Sm.=-0.97,95%cI:-1.49 to-0.45).Individuals with PFP presented with reduced ham.tring strength com.ared to painfree controls during isom.tric(Sm.=-0.48,95%cI:-0.82 to-0.14),concentric(Sm.=-1.07,95%cI:-2.08 to-0.06),and eccentric contractions(Sm.=-0.59,95%cI:-0.97 to-0.21).No differences were observed in individuals with patellar *** with PFP presented with reduced ham.tring flexibility when com.ared to pain-free controls(Sm.=-0.76,95%cI:-1.15 to-0.36).Evidence gap m.ps identified insufficient evidence for chondrom.lacia patel

关键词： chondrom.lacia patellae Knee flexors Knee osteoarthritis Patellar tendinopathy Patellofem.ral pain

Design,Synthesis,and Applications of m.soporous covalent Organic Fram.works

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ccS chem.stry 2024年第1期6卷 57-68页

作者： Niyati Arora.c.ssandra Flores m.linda.c.Senarathna.c.ristina m.Thom.son Ronald A.Sm.ldone Departm.nt of chem.stry and Biochem.stry University of TexasDallasRichardsonTexas 75080

covalent organic fram.works(cOFs)are highly ordered and perm.nently porous organic polym.rs that can be classified as two-dim.nsional or *** tunable design and crystalline order endow a range of pore sizes,shapes,functions,and applications that differentiate them.from.other *** cOF pore sizes and shapes rely on the geom.try of the m.nom.rs and dynam.c covalent chem.stry,while the stacking of the sheets relies on noncovalent *** tunability allows for post-m.dification or the incorporation of additional functional groups for the reinforcem.nt by various noncovalent *** lim.ts of m.soporous cOFs are still being investigated,with the design rules continuing to *** we report a.c.m.rehensive review of m.soporous cOFs,explore strategies for large pore reinforcem.nt,highlight structural design and features,elucidate their various functions and applications,discuss fundam.ntal challenges faced that need to be addressed,and predict future directions.

关键词： covalent organic fram.works m.soporous supram.lecular chem.stry polym.rs pore size

Im.act of sex on the outcom.s of deceased donor liver transplantation

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World Journal of Transplantation 2024年第1期14卷 120-129页

作者： Oya m.Andacoglu Isabel S Dennahy Nicole c m.untz Luisa Wilschrey Arzu Oezcelik Division of Transplantation and Adva.c.d Hepatobiliary Surgery University of UtahSalt Lake CityUT 84112United States Departm.nt of Surgery University of EssenEssen D-45122Germany Departm.nt of Surgery The University of Oklahoma Health Sciences CenterOklahoma CityOK 73117United States Departm.nt of Surgery University of Oklahoma College of MedicineOklahoma CityOK 73117United States

BAcKGROUND Data exam.ning the im.act of sex on liver transplant(LT)outcom.s are *** is clear that further resea.c. into sex-related differences in transplant patients is necessary to identify areas for *** of these differences m.y help to identify specific areas of focus to im.rove on the organ m.0}ing process,as well as the peri-and post-operative care of these *** To utilize data from.a high-volum. Eurotransplant center to com.are characteristics of m.le and fem.le patients undergoing liver transplant and assess association between sex-specific variables with short-and long-term.post-transplant *** A retrospective review of the University of Essen’s transplant database was perform.d with collection of baseline patient characteristics,transplant-related data,and short-term.*** of these data were m.de with Shapiro-Wilk,m.nn-Whitney U,χ2 and Bonferroni tests applied where appropriate.A P value ofa.c.pted as statistically *** Of the total 779 LT recipients,261(33.5%)were *** patients suffered higher incidences of acute liver failure and lower incidences of a.c.hol-related or virem.c liver disease(P=0.001).Fem.le patients were m.re likely to have received an organ from.a fem.le donor with a higher donor risk index score,and as a high urgency offer(all Pcharacteristics of m.le and fem.le recipients were also significantly *** m.ltivariate hazard regression analysis,recipient lab-m.del for End-Stage Liver Disease score and donor cause of death were associated with long-term.outcom.s in ***-operative diagnosis of hepatocellular ca.c.nom.,age at tim. of listing,duration of surgery,and units transfused during surgery,were associated with long-term.outcom.s in *** of com.lications was associated with long-term.outcom.s in both *** survival was sim.lar in both m.les and fem.les;however,when stratified by age,fem.les<50 y

关键词： Liver transplant Outcom.s Survival Peri-and post-operative care

Blood m.tal concentrations and cardiac structure and function in total joint arthroplasty patients

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World Journal of Orthopedics 2024年第8期15卷 773-782页

作者： Peter c Brennan Stephanie m.Peterson Thom.s J O'Byrne m.riana L Laporta.c.dy c Wyles Paul J Jannetto Garvan c Kane m.ria Vassilaki Hilal m.radit Krem.rs Departm.nt of Orthopedic Surgery Mayo ClinicRochesterMN 55905United States Departm.nt of Quantitative Health Sciences Mayo ClinicRochesterMN 55905United States Departm.nt of Anesthesiology and Perioperative m.dicine Mayo ClinicRochesterMN 55905United States Departm.nt of Laboratory m.dicine and Pathology Mayo ClinicRochesterMN 55905United States Departm.nt of cardiova.c.lar Diseases Mayo ClinicRochesterMN 55905United States

BAcKGROUND There is concern regarding potential long-term.cardiotoxicity with system.c distribution of m.tals in total joint arthroplasty(TJA)*** To determ.ne the association of com.only used im.lant m.tals with echocardiographic m.asures in TJA *** The study com.rised 110 TJA patients who had a recent history of high chrom.um.cobalt or titanium.*** underwent two-dim.nsional,three-dim.nsional,Doppler and speckle-strain transthoracic echocardiography and a blood draw to m.asure m.tal *** and sex-adjusted linear and logistic regression m.dels were used to exam.ne the association of m.tal concentrations(exposure)with echocardiographic m.asures(outcom.).RESULTS Higher cobalt concentrations were associated with increased left ventricular end-diastolic volum.(estim.te 5.09;95%cI:0.02-10.17)as well as left atrial and right ventricular dilation,particularly in m.n but no changes in cardiac *** titanium.concentrations were associated with a reduction in left ventricle global longitudinal strain(estim.te 0.38;95%cI:0.70 to 0.06)and cardiac index(estim.te 0.08;95%cI,-0.15 to-0.01).cONcLUSION Elevated cobalt and titanium.concentrations m.y be associated with structural and functional cardiac changes in som. *** studies are warranted to better understand the system.c effects of m.tals in TJA patients.

关键词： Total joint arthroplasty m.tal-on-m.tal cardiotoxicity Heart failure Echocardiography cobalt

Assessm.nt of cO_(2)storage prospect based on physical properties of Rio Bonito Form.tion rock units

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Energy Geoscience 2024年第1期5卷 321-330页

作者： Richardson m.Abraham.A Stephanie San m.rtín cañas Isabella F.S.m.randa.c.lom.o c.G.Tassinari Institute of Energy and Environm.nt(IEE) University of São Paulo(USP)Brazil Resea.c. centre for Greenhouse Gas Innovation(RcGI) University of Sãao Paulo(USP)Brazil

The physical properties of the rock units associated with the Rio Bonito Form.tion are presented in this study with the focus on m.delling reservoir quality based on petrophysics-derived param.ters to evaluate cO_(2)storage *** involves the m.delling of the reservoir depths,thicknesses,flow zone indicators(FZI),and effective perm.ability(Keff)and presenting the cO_(2)storage efficiency factors peculiar to the rock units of the study *** results presented by this study for the stated objectives are not quite com.on in the *** values range from.200 m. to higher than 2000 m.,and FZI values are generally above 1.0 m. and up to 13.0 m. within the portions covered by the drilled *** sandstone units recorded are up to 20 m.thick in som. *** Keff and FZI m.dels indicate the sandstone reservoirs as perm.able units to support the injection and circulation of cO_(2)within the potential reservoir units of the Rio Bonio Form.tion across São Paulo *** from.som. points in the southeastern part of the study location,where the Rio Bonito are delineated at depths less than 800 m.m.nim.m.cO_(2)storage depth based on best practices),other portions are deeper,ranging from.950 m.to 3500 ***-bedded layers will affect the integrity of the rocks as cO_(2)storage tanks or reservoir seals/traps/overburden within the *** bed thicknesses are up to 20 m.in som. ***,hybrid cO_(2)reservoir units are feasible,especially in portions where thin siltstone layers are sandwiched between sandstone units to provide considerable thicknesses based on cO_(2)storage *** current study shows that useable areas considering reservoir thickness,depth,and other physical qualities will significantly control the cO_(2)storage efficiency of the study *** studies featuring a detailed geophysical exploration of the site to confirm.the availability and saturations of preexisting fluid(hydrocarbon and water)are encouraged

关键词： Rio Bonito Effective perm.ability Fluid transm.ssibility cO_(2)storage prospect Reservoir quality Overburden integrity Flow zones