检索结果-南通市图书馆

Effective and Efficient Feature Selection for Large-scale Data Using Bayes' Theorem

在线全文

学校读者我要写书评

暂无评论

International Journal of Automation and computing 2009年第1期6卷 62-71页

作者： subramanian Appavu Alias Balamurugan Ramasamy Rajaram Department of Information Technology Thiagarajar College of Engineering Department of Computer Science and Information Technology Thiagarajar College of Engineering

This paper proposes one method of feature selection by using Bayes＇ theorem. The purpose of the proposed method is to reduce the computational complexity and increase the classification accuracy of the selected feature subsets. The dependence between two attributes （binary） is determined based on the probabilities of their joint values that contribute to positive and negative classification decisions. If opposing sets of attribute values do not lead to opposing classification decisions （zero probability）, then the two attributes are considered independent of each other, otherwise dependent, and one of them can be removed and thus the number of attributes is reduced. The process must be repeated on all combinations of attributes. The paper also evaluates the approach by comparing it with existing feature selection algorithms over 8 datasets from University of California, Irvine （UCI） machine learning databases. The proposed method shows better results in terms of number of selected features, classification accuracy, and running time than most existing algorithms.

关键词： Data mining classification feature selection dimensionality reduction Bayes' theorem.

Hairpin Priming Is Better Suited than In Vitro Polyadenylation to Generate cDNA for Plant miRNA qPCR

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2013年第1期6卷 229-231页

作者： Sajag Adhikari Marie Turner Senthil subramanian Department of Plant Science South Dakota State University Brookings SD 57007 USA

Dear Editor, microRNAs （miRNAs） are short non-coding RNAs that play crucial roles in plant development and responses to biotic and abiotic stresses, miRNA biogenesis starts with the tran- scription of a hairpin-forming pri-miRNA that is sequentially cleaved yielding a duplex RNA molecule consisting of the mature miRNA （typically 21-22 nt in length） and miRNA＊. Typically, mature miRNAs are the active forms and are incor- porated into different RNA-induced silencing complexes that regulate gene expression by inhibition of translation or cleavage of complementary mRNAs （reviewed in Axtell et al., 2011）.

关键词： miRNAs 基因植物聚腺苷非生物胁迫酸化体外引发非编码RNA

Electronic structure and bonding interactions in Ba1-xSrxZr0.1Ti0.9O3 ceramics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Materials Science 2017年第2期11卷 182-189页

作者： Jegannathan MANGAIYARKKARASI subramanian SASIKUMAR Olai Vasu SARAVANAN Ramachandran SARAVANAN PG and Research Department of Physics NMSSVN College Nagamalai Madurai-625 019 Tamil Nadu India Research Centre and PG Department of Physics The Madura College Madurai-625 011 Tamil Nadu India

An investigation on the precise electronic structure and bonding interactions has been carried out on Ba1-xSrxZr0.1Ti0.9O3 （short for BSZT, x = 0, 0.05, 0.07 and 0.14） ceramic systems prepared via high-temperature solid state reaction technique. The influence of Sr doping on the BSZT structure has been examined by characterizing the prepared samples using PXRD, UV-visible spectrophotometry, SEM and EDS. Powder profile refinement of X-ray data confirms that all the synthesized samples have been crystallized in cubic perovskite structure with single phase. Charge density distribution of the BSZT systems has been completely analyzed by the maximum entropy method （MEM）. Co-substitution of Sr at the Ba site and Zr at the Ti site into the BaTiOz structure presents the ionic nature between Ba and O ions and the covalent nature between Ti and O ions, revealed from MEM calculations. Optical band gap values have been evaluated from UV-visible absorption spectra. Particles with irregular shapes and well defined grain boundaries are clearly visualized from SEM images. The phase purity of the prepared samples is further confirmed by EDS qualitative spectral analysis.

关键词： barium titanate X-ray diffraction Rietveld refinement maximum entropy method bonding

Transparent, stretchable, and rapid-response humidity sensor for body-attachable wearable electronics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2017年第6期10卷 2021-2033页

作者： Tran Quang Trung Le Thai Duy subramanian Ramasundaram Nae-Eung Lee School of Advanced Materials Science & Engineering Sungkyunkwan University (SKKU) Suwon Kyunggi-do 16419 Republic of Korea Center for Water Resource Cycle Research Korea Institute of Science and Technology Hwarang-ro 14 gil Seongbuk-gu Seoul 02793 Republic of Korea SKKU Advanced Institute of Nanotechnology (SAINT) SKKU Suwon Kyunggi-do 16419 Republic of Korea Samsung Advanced Institute for Health Sciences & Technology (SAIHST) SKKU Suwon Kyunggi-do 16419 Republic of Korea

Stretchable and conformal humidity sensors that can be attached to the human body for continuously monitoring the humidity of the environment around the human body or the moisture level of the human skin can play an important role in electronic skin and personal healthcare applications. However, most stretchable humidity sensors are based on the geometric engineering of non-stretchable components and only a few detailed studies are available on stretchable humidity sensors under applied mechanical deformations. In this paper, we propose a transparent, stretchable humidity sensor with a simple fabrication process, having intrinsically stretchable components that provide high stretchability, sensitivity, and stability along with fast response and relaxation time. Composed of reduced graphene oxide-polyurethane composites and an elastomeric conductive electrode, this device exhibits impressive response and relaxation time as fast as 3.5 and 7 s, respectively. The responsivity and the response and relaxation time of the device in the presence of humidity remain almost unchanged under stretching up to a strain of 60% and after 10,000 stretching cycles at a 40% strain. Further, these stretchable humidity sensors can be easily and conformally attached to a finger for monitoring the humidity levels of the environment around the human body, wet objects, or human skin.

关键词： transparent stretchablehumidity sensor reduced graphene oxide wearable electronics body-attachable intrinsically stretchable components

Thymoquinone inhibits the migration of mouse neuroblastoma(Neuro-2a) cells by down-regulating MMP-2 and MMP-9

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Natural Medicines 2016年第12期14卷 904-912页

作者： Arumugam Paramasivam subramanian Raghunandhakumar Jayaseelan Vijayashree Priyadharsini Gopalswamy Jayaraman Department of Genetics Dr. ALM Post Graduate Institute of Basic Medical Sciences University of Madras Sekkizhar campusTaramani Chennai-600113 India Department of Biochemistry University of Madras Guindy Campus Chennai-600025 India

Thymoquinone(TQ), an active component derived from the medial plant Nigella sativa, has been used for medical purposes for more than 2 000 years. Recent studies have reported that TQ blocked angiogenesis in animal model and reduced migration, adhesion, and invasion of glioblastoma cells. We have recently shown that TQ could exhibit a potent cytotoxic effect and induce apoptosis in mouse neuroblastoma(Neuro-2a) cells. In the present study, TQ treatment markedly decreased the adhesion and migration of Neuro-2a cells. TQ down-regulated MMP-2 and MMP-9 protein expression and m RNA levels and their activities. Furthermore, TQ significantly down-regulated the protein expression of transcription factor NF-κB(p65) but not significantly altered the expression of N-Myc. Taken together, our data indicated that TQ's inhibitory effect on the migration of Neuro-2a cells was mediated through the suppression of MMP-2 and MMP-9 expression, suggesting that TQ treatment can be a promising therapeutic strategy for human malignant neuroblastoma.

关键词： Thymoquinone Neuroblastoma Migration NF-κB MMP-2

Influence of two different dietary zinc sources in freshwater prawn Macrobrachium rosenbergii post larvae

在线全文

学校读者我要写书评

暂无评论

Journal of Oceanology and Limnology 2019年第1期37卷 290-299页

作者： THIRUNAVUKKARASU Muralisankar PERIYAKALI Saravana Bhavan subramanian Radhakrishnan PERUMAL Santhanam Aquatic Ecology Laboratory Department of Zoology Bharathiar University Marine Planktonology and Aquaculture Laboratory Department of Marine Science Bharathidasan University Crustacean Biology Laboratory Department of Zoology Bharathiar University Department of Arid Land Agriculture College of Food & Agriculture United Arab Emirates University

A feeding experiment was conducted to evaluate the ef fects of bulk zinc(B-Zn) and zinc nanoparticles(Zn-NPs) on survival, growth, compositions of amino acid and fatty acid, and nonspeci?c immune responses of the freshwater prawn, Macrobrachium rosenbergii post larvae. The B-Zn(size 10 μm)and Zn-NPs(size 50 nm) were supplemented separately with the basal feeds of M. rosenbergii at 60 mg/kg and feed without supplementation of any Zn source was served as a control. M. rosenbergii were fed these feeds for 90 days and the results showed that signi?cant( P <0.05) improvements in survival, growth, feed intake,speci?c growth rate, essential amino acids, unsaturated fatty acids, nonspeci?c immune responses(total haemocytes and dif ferential haemocytes count) of M. rosenbergii fed with B-Zn and Zn-NPs supplemented feeds when compared to control. Among these Zn sources, Zn-NPs supplemented feeds fed prawns showed signi?cantly( P <0.05) better performance than that of B-Zn and control. Hence, present study suggests that the 60 mg/kg Zn-NPs can be supplemented with basal feeds of M. rosenbergii for regulating better survival and growth.

关键词： survival feed amino acid fatty acid haemocytes zinc nanoparticles

Rapid adsorption of toxic Pb(Ⅱ) ions from aqueous solution using multiwall carbon nanotubes synthesized by microwave chemical vapor deposition technique

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2016年第7期28卷 143-155页

作者： Nabisab Mujawar Mubarak Jaya Narayan Sahu Ezzat Chan Abdullah Natesan subramanian Jayakumar Department of Chemical Engineering Faculty of Engineering and Science Curtin University Sarawak Department of Chemical Engineering Faculty of Engineering University of Malaya Petroleum and Chemical Engineering Programme Area Faculty of Engineering Institut Teknologi Brunei Malaysia–Japan International Institute of Technology Universiti Teknologi Malaysia Jalan Semarak

Multiwall carbon nanotubes（MWCNTs） were synthesized using a tubular microwave chemical vapor deposition technique, using acetylene and hydrogen as the precursor gases and ferrocene as catalyst. The novel MWCNT samples were tested for their performance in terms of Pb（Ⅱ）binding. The synthesized MWCNT samples were characterized using Fourier Transform Infrared（FT-IR）, Brunauer, Emmett and Teller（BET）, Field Emission Scanning Electron Microscopy（FESEM） analysis, and the adsorption of Pb（Ⅱ） was studied as a function of p H,initial Pb（Ⅱ） concentration, MWCNT dosage, agitation speed, and adsorption time, and process parameters were optimized. The adsorption data followed both Freundlich and Langmuir isotherms. On the basis of the Langmuir model, Qmaxwas calculated to be 104.2 mg/g for the microwave-synthesized MWCNTs. In order to investigate the dynamic behavior of MWCNTs as an adsorbent, the kinetic data were modeled using pseudo first-order and pseudo second-order equations. Different thermodynamic parameters, viz., ΔH0, ΔS0and ΔG0were evaluated and it was found that the adsorption was feasible, spontaneous and endothermic in nature. The statistical analysis revealed that the optimum conditions for the highest removal（99.9%） of Pb（Ⅱ） are at p H 5, MWCNT dosage 0.1 g, agitation speed 160 r/min and time of 22.5 min with the initial concentration of 10 mg/L. Our results proved that microwave-synthesized MWCNTs can be used as an effective Pb（Ⅱ） adsorbent due to their high adsorption capacity as well as the short adsorption time needed to achieve equilibrium.

关键词： Microwave Heavy metal Wastewater treatment Adsorption MWCNTs Lead

Implications of m6A modification in autoimmune disorders

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2020年第5期17卷 550-551页

作者： Arumugam Paramasivam Jayaseelan Vijayashree Priyadharsini subramanian Raghunandhakumar Saveetha UniversityChennaiIndia Centre for Biotechnology Anna UniversityChennaiIndia

N6-Methyladenosine(m6A)is the most common and abundant modification of RNA molecules,including mRNAs,microRNAs(miRNAs),and long noncoding RNAs(lncRNAs).1 The m6A modification is catalyzed and dynamically regulated by recently discovered enzymes termed“writers”(methyltransferases including METTL3,METTL14,and WTAP),“erasers”(demethylases including FTO and ALKBH5)and“readers”(m6A-binding proteins including YTHDC1,YTHDC2,YTHDF1,YTHDF2,and YTHDF3).These modifications were recently shown to be involved in the regulation of different biological processes.

关键词： autoimmune m6A modification

Novel degradation products of argatroban: Isolation, synthesis and extensive characterization using NMR and LC-PDA-MS/Q-TOF

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Pharmaceutical Analysis 2018年第2期8卷 86-95页

作者： Vinodh Guvvala Venkatesan Chidambaram subramanian Jaya Shree Anireddy Mahesh Konda Centre for Chemical Science&Technology Institute of Science& Technology JNTUH Gland Pharma Ltd. Research and Development D.P.Pally

Forced degradation study of argatroban under conditions of hydrolysis(neutral, acidic and alkaline), oxidation,photolysis and thermal stress, as suggested in the ICH Q1 A(R2), was accomplished. The drug showed significant degradation under hydrolysis(acidic, alkaline) and oxidation(peroxide stress) conditions. The drug remained stable under thermal and photolytic stress conditions. In total, seven novel degradation products(DP-1 to DP-7) were found under diverse conditions, which were not reported earlier. The chemical structures of these degradation products were characterized by ~1H NMR,^(13)C NMR, 2 D NMR, Q-TOF-MSnand IR spectral analysis and the proposed degradation products structures were further confirmed by the individual synthesis.

关键词： Argatroban Forced degradation NMR LC-PDA LC-MS/Q-TOF-MSn