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Optimizing water resources allocation in the Haihe River basin under groundwater sustainability constraints

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Journal of Geographical Sciences 2019年第6期29卷 935-958页

作者： Grith mARTINSEN LIU Suxia mO Xingguo bauer-GOTTWEIN Peter Key Laboratory of Water Cycle and Related Land Surface Processes Institute of Geographic Sciences and Natural Resources ResearchCAS Department of Environmental Engineering Technical University of Denmark College of Resources and Environment/Sino-Danish Center for Education and Research University of Chinese Academy of Sciences Sino-Danish Center for Education and Research

This study applies a hydroeconomic optimization method for water resources management in the highly water stressed Haihe River basin. A multi-objective, multi-temporal deterministic hydroeconomic optimization model has been built to quantify the economic trade-offs and reveal "minimum cost strategies" when reducing groundwater abstraction to sustainable levels. A complex basin representation, with ～140,000 decision variables is formulated where each decision variable represents a flow-path from a water source to a sink. Available water sources are runoff generated by the sub-basins upstream the nine major surface water reservoirs, the inter-basin transfers from Yellow River and South to North Water Transfer Project(SNWTP) and the natural groundwater recharge to the three main groundwater aquifers. Water demands, i.e. sinks, are aggregated for each model sub-basin in categories of the major agricultural users, domestic, industrial and ecological water demands. Each demand is associated with a curtailment cost and groundwater abstraction with a pumping cost. Groundwater overdraft is constrained in each model scenario, ranging from unlimited overdraft in the plain area groundwater aquifer to sustainable abstractions over an 8-year period. Inflow upstream Yuqiao reservoir, and the inter-basin transfers from SNWTP and Yellow River are identified as the water resources with the highest increase in average shadow prices when limiting groundwater overdraft. An increase in inflow shadow prices of 37.5% indicates that these water sources will be most valuable if sustainable groundwater abstraction should be achieved. The shadow prices of water sources reveal when and where in the Haihe River basin users are curtailed if water resources are managed in the most optimal way. Average shadow prices of 1.6 yuan/m3 for all surface water sources in the sustainable abstraction scenarios shows that overdraft can be avoided by curtailment of users with a willingness-to-pay ≤1.6 yuan/m3.

关键词： Haihe River China hydroeconomic optimization linear programming groundwater sustainability spatio-temporal economic trade-offs decision support

macrophage-specific inhibition of the histone demethylase JmJD3 decreases STING and pathologic inflammation in diabetic wound repair

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Cellular & molecular Immunology 2022年第11期19卷 1251-1262页

作者： Christopher O.Audu William J.melvin Amrita D.Joshi Sonya J.Wolf Jadie Y.moon Frank m.Davis Emily C.Barrett Kevin D.mangum Hongping Deng Xianying Xing Rachel Wasikowski Lam C.Tsoi Sriganesh B.Sharma Tyler m.bauer James Shadiow matthew A.Corriere Andrea TObi Steven LKunkel Benjamin Levi Bethany Bmoore Johann EGudjonsson Andrew mSmith Katherine A.Gallagher Department of Surgery Section of Vascular SurgeryUniversity of MichiganAnn ArborMIUSA Department of microbiology and Immunology University of MichiganAnn ArborMIUSA Department of medicinal Chemistry University of MichiganAnn ArborMIUSA Department of Surgery Section of General SurgeryUniversity of MichiganAnn ArborMIUSA Department of Bioengineering University of IllinoisUrbana-ChampaignChampaignILUSA Department of Dermatology University of MichiganAnn ArborMIUSA Department of Pathology University of MichiganAnn ArborMIUSA Department of Surgery University of Texas Southwestern Medical CenterDallasTXUSA

macrophage plasticity is critical for normal tissue repair following *** pathologic states such as diabetes,macrophage plasticity is impaired,and macrophages remain in a persistent proinflammatory state;however,the reasons for this are ***,using single-cell RNA sequencing of human diabetic wounds,we identified increased JmJD3 in diabetic wound macrophages,resulting in increased inflammatory gene ***,we report that in wound healing,JmJD3 directs early macrophage-mediated inflammation via JAK1,3/STAT3 ***,in the diabetic state,we found that IL-6,a cytokine increased in diabetic wound tissue at later time points post-injury,regulates JmJD3 expression in diabetic wound macrophages via the JAK1,3/STAT3 pathway and that this late increase in JmJD3 induces NFκB-mediated inflammatory gene transcription in wound macrophages via an H3K27me3 ***,RNA sequencing of wound macrophages isolated from mice with JmJD3-deficient myeloid cells(Jmjd3f/fLyz2Cre+)identified that the STING gene(Tmem173)is regulated by JmJD3 in wound *** limits inflammatory cytokine production by wound macrophages during ***,in diabetic mice,its role changes to limit wound repair and enhance *** finding is important since STING is associated with chronic inflammation,and we found STING to be elevated in human and murine diabetic wound macrophages at late time ***,we demonstrate that macrophage-specific,nanoparticle inhibition of JmJD3 in diabetic wounds significantly improves diabetic wound repair by decreasing inflammatory cytokines and *** together,this work highlights the central role of JmJD3 in tissue repair and identifies cell-specific targeting as a viable therapeutic strategy for nonhealing diabetic wounds.

关键词： wound healing epigenetics diabetes JmJD3 STING

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省时又省力，让你的秀发完美无瑕

父母世界 2018年第5期 90-91页

作者： Shannon m.bauer 朱思旸(翻译)

洗发之前，选一瓶适合自己发型的洗发水：如果是卷发，需要有柔顺配方的洗发水：细软的头发需要能让头发蓬松的洗发水；如果是染发，需要无氟洗发水。

关键词：省力洗发水头发

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发动机散热器的标准化

汽车与新动力 2003年第2期 61-62页

作者： bauer D Flik m Kern J 蔡杰浙江银轮机械股份有限公司

在制造发动机散热器时对产生的所有费用进行全面的分析显示,对欧洲市场来说,标准散热器芯子规格的最佳数量为10。根据这个知识,贝尔(Behr)公司开发了一个标准化的机械连接的散热器芯子设计程序,这个程序包括优化的特别细长的圆管和扁管... 详细信息

在制造发动机散热器时对产生的所有费用进行全面的分析显示,对欧洲市场来说,标准散热器芯子规格的最佳数量为10。根据这个知识,贝尔(Behr)公司开发了一个标准化的机械连接的散热器芯子设计程序,这个程序包括优化的特别细长的圆管和扁管系统。这种结构型式的标准化散热器在成本、质量和样品制造方面都具有显著的优点。

关键词：发动机散热器标准

High precision W mass measurement from CDF Ⅱ conflicts with the standard model

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Science Bulletin 2022年第13期67卷 1313-1316页

作者： Gerry bauer Zhen Hu Lei Wu Kai Yi Jingqing Zhang School of Physics and Technology Nanjing Normal UniversityNanjing 210023China Department of Physics Tsinghua UniversityBeijing 100084China

The international CDF Ⅱ Collaboration at Fermilab(FNAL)announced the most precise measurement to date of the W boson mass as 80,433.5 ± 9.4 meV on April 8, 2022 [1]. For the first time single digit meV precision has... 详细信息

关键词： precise mass Fermi

Application of Amine-Functionalized Cellulose Foam for CO2 Capture and Storage in the Brewing Industry

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Journal of Renewable materials 2018年第3期6卷 219-225页

作者： Lars Helmlinger Yejun Zhu Julia Gensel Thomas Neumeyer Stefan Thater Franziska Strube Christoph bauer Bernd Rosemann Volker Altstadt Neue materialien Bayreuth GmbH Gottlieb-Keim-Straße 6095448 BayreuthGermany Chair for Environmentally Friendly Production Technology Universitätsstraße 3095447 BayreuthGermany

Due to a lack of technology,smaller breweries simply dump excess CO2 into the atmosphere,fueling the greenhouse effect and global ***-of-the-art CO2 capture technologies using nanofibrillated cellulose are expensive and require laborious ***,there is a high demand for affordable alternatives in order to reduce the environmental impact in this industry *** work describes a novel route for a quick and cost-efficient synthesis of amine-functionalized cellulose pellets by a surfactantassisted steam explosion *** values with this method were porosity of 92%and density of 67 g/cm^*** on polyethylenimine(PEI)content and distribution revealed a maximum PEI concentration of 20 wt%with decreasing concentration to the core of a *** stability against brewery exhaust gas was determined and CO2 release at^120℃ could be *** tests under simulated working conditions with a novel laboratory reactor yielded a CO2 capacity of 1.0 mmol/g or 67 mol/m^3,which is comparable to values known from the literature for other cellulose-based adsorbents.

关键词： CO2 capture carbon capture poly(ethylenimine) cellulose adsorption

Comprehensive metabolic Profiling of modified Gegen Qinlian Decoction by Ultra-high-Performance Liquid Chromatography-Diode Array Detection-Q-Exactive-Orbitrap-Electrospray Ionization-mass Spectrometry/mass Spectrometry and Application of High-Performance

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World Journal of Traditional Chinese medicine 2021年第1期7卷 11-32页

作者： Xuehong Nöst Eva-maria Pferschy-Wenzig Xiao-Tong Yu min Li Xiao-Lin Tong Rudolf bauer Department of Pharmacognosy Institute of Pharmaceutical SciencesUniversity of GrazGrazAustria Department of Endocrinology Guang’Anmen HospitalChina Academy of Chinese Medical SciencesBeijingChina Department of Endocrinology Laboratory of Molecular BiologyGuang’Anmen HospitalChina Academy of Chinese Medical SciencesBeijingChina

Objective:Gegen Qinlian decoction(GQD)is a classical traditional Chinese medicine formulation which has been used for almost 2000 *** Guang'anmen Hospital,Beijing,a modified GQD version(m GQD)with seven instead of four herbal ingredients has been applied to treat Type 2 *** control is a crucial prerequisite for the therapeutic application of herbal *** the identification of products derived from classical GQD,the Chinese Pharmacopeia requires the analysis of only three marker *** m GQD is a more complex mixture containing seven herbs and hundreds of constituents,the pharmacopoeia method for GQD is *** and methods:A more comprehensive characterization of the formula's constituents has been developed using ultra-high-performance liquid chromatography-diode array detection(UHPLC-DAD)-Q-Exactive-mass spectrometry(mS)in electrospray ionization positive and negative ***,a new method for the fingerprint analysis of m GQD via high-performance thin-layer chromatography(HPTLC)has been ***:Altogether,91 compounds have been assigned to their originating plants and 84 substances were identified either by comparison with authentic references or with data from the *** HPTLC method is based on the application of two different mobile phases and is able to detect both lipophilic and hydrophilic constituents of m ***:The modified GQD was extensively characterized by UHPLC combined with DAD and Q-Exactive Orbitrap high-resolution mS detection,leading to the assignment and identification of compounds present in the *** addition,a new method for the fingerprint analysis of the m GQD using HPTLC was established,which allows fast and simple identification of the herbal ingredients in the mixture.

关键词： Fructus jujubae HPTLC modified gegen qinlian decoction Radix et rhizoma glycyrrhizae praeparata cum melle Radix puerariae lobatae Radix scutellariae Rhizoma coptidis Rhizoma anemarrhenae Rhizoma zingiberis UHPLC-DAD-Q-Exactive-mS

metabolic Profiling of Lonicera Species for the Identification of Constituents Relevant for Inhibition of NO production in LPS-/IFN-γ-stimulated RAW 264.7 mouse macrophages

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Metabolic Profiling of Lonicera Species for the Identificati...

multi-mW,few-cycle mid-infrared continuum spanning from 500 to 2250cm^(−1)

第十四届全国中药和天然药物学术研讨会

作者： S.Ortmann m.monschein J.Hartler Y.m.Zhao J.H.miao G.G.Thallinger R.bauer University of Graz Graz-University of Technology Guangxi Botanical Garden of medicinal Plants

The flowers(Jin Yin Hua金银花)and the stems(Ren Dong Teng忍冬藤)of Lonicera japonica Thunb.(Caprifoliaceae)are commonly used in traditional Chinese medicine to clear heat and relieve toxicity[1].Based on the results of a screening of a large number of Chinese medicinal plants,the genus Lonicera was chosen for a proof-of-principle study in

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Light(Science & Applications) 2017年第1期6卷 1-6页

作者： Jinwei Zhang Ka Fai mak Nathalie Nagl marcus Seidel Dominik bauer Dirk Sutter Vladimir Pervak Ferenc Krausz Oleg Pronin max-Planck-Institute of Quantum Optics Hans-Kopfermann-Str.1Garching 85748Germany Ludwig-maximilians-University munich Am Coulombwall 1Garching 85748Germany TRUmPF Laser GmbH Aichhalder Straße 39Schramberg D-78713Germany

The demand for and usage of broadband coherent mid-infrared sources,such as those provided by synchrotron facilities,are *** most organic molecules exhibit characteristic vibrational modes in the wavelength range between 500 and 4000 cm^(−1),such broadband coherent sources enable micro-or even nano-spectroscopic applications at or below the diffraction limit with a high signal-to-noise ratio1–*** techniques have been applied in diverse fields ranging from life sciences,material analysis,and time-resolved *** we demonstrate a broadband,coherent and intrinsically carrier-envelope-phase-stable source with a spectrum spanning from 500 to 2250 cm^(−1)(−30 dB)at an average power of 24mW and a repetition rate of 77 *** performance is enabled by the first mode-locked thin-disk oscillator operating at 2μm wavelength,providing a tenfold increase in average power over femtosecond oscillators previously demonstrated in this wavelength ***-octave spectral coverage from this compact and power-scalable system opens up a range of time-and frequency-domain spectroscopic applications.

关键词： coherent repetition oscillator