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加强区域化建设提升生物经济影响力

世界科技研究与发展 2022年第6期44卷 790-798页

作者： ulrich schurr Christian Klar Heike Slusarczyk 黄小容(翻译) 尤利希研究中心IBG-2 德国尤利希中国科学院成都文献情报中心成都610299

不断发布或更新的生物经济战略反映出各国/地区发展生物经济的雄心壮志。生物经济概念的不清晰(模糊性)及方法的多样性常引起争议,公众很难理解生物经济是做什么以及它能为现代社会发展提供什么实质上的解决方案,导致生物经济及其方法... 详细信息

不断发布或更新的生物经济战略反映出各国/地区发展生物经济的雄心壮志。生物经济概念的不清晰(模糊性)及方法的多样性常引起争议,公众很难理解生物经济是做什么以及它能为现代社会发展提供什么实质上的解决方案,导致生物经济及其方法难以在实践中得到应用,甚至被简化为生物技术。基于上述分析,提出本文的核心观点——生物经济区域化,并给出了区域化背景下生物经济的定义:在可持续经济的框架内,生产和利用生物资源(包括知识)为所有部门提供产品、工艺和服务。随后,本文分析了欧盟发展可持续生物经济区域的相关举措,并重点阐述了发展生物经济所必需的要素,包括自然资源、人力资本、工业资本和技术等。最后介绍与生物经济相关的区域产业集群,其中重点介绍了德国莱茵生物经济示范区和生物经济科学中心。

关键词：生物经济区域化莱茵生物经济示范区生物经济科学中心

Plant Phenotyping:Past,Present,and Future

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Plant Phenomics 2019年第1期1卷 179-184页

作者： Roland Pieruschka Uli schurr IBG-2 Plant Sciences Forschungszentrum Julich GmbHD-52425 ulichGermany

A plant develops the dynamic phenotypes from the interaction of the plant with the *** these processes that span plant’s lifetime in a permanently changing environment is essential for the advancement of basic plant science and its translation into application including breeding and crop *** plant research community was thus confronted with the need to accurately measure diverse traits of an increasingly large number of plants to help plants to adapt to resource-limiting environment and low-input *** this overview,we outline the development of plant phenotyping as a multidisciplinary *** sketch the technological advancement that laid the foundation for the development of phenotyping centers and evaluate the upcoming challenges for further advancement of plant phenotyping specifically with respect to standardization of data acquisition and ***,we describe the development of the plant phenotyping community as an essential step to integrate the community and effectively use the emerging synergies.

关键词： Plant breeding sketch

L1 is a potential marker for poorly-differentiated pancreatic neuroendocrine carcinoma

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World Journal of Gastroenterology 2006年第1期12卷 94-98页

作者： Jussuf T Kaifi ulrich Zinnkann Emre F Yekebas Paulus G schurr Uta Reichelt Robin Wachowiak Henning C Fiegel Susann Petri Melitta Schachner Jakob RIzbicki Department of General Visceral and Thoracic SurgeryUniversity Medical Center Hamburg-EppendorfHamburgGermany Institute for Pathology University Medical Center Hamburg-EppendorfHamburgGermany Department of Pediatric Surgery University Medical Center Hamburg-EppendorfHamburgGermany Center for Molecular Neurobiology University Medical Center Hamburg-EppendorfHamburgGermany

AIM： To determine the expression of L1 in pancreatic neuroendocrine tumor and to correlate it with WHO classification of this tumor. METHODS： We retrospectively analyzed L1 expression in 63 cases of pancreatic neuroendocrine tumor by immunohistochemistry on paraffin sections of primary tumors or metastases. Staining was performed by peroxidase technique with monoclonal antibody U3127.11 against human L1. All tumors were classified according to WHO classification as well-differentiated neuroendo- crine tumors and carcinomas or poorly-differentiated neuroendocrine carcinomas. RESULTS： LI was detected in 5 （7.9%） of 63 pancreatic neuroendocrine tumors. Four （44.4%） of 9 poorlydifferentiated carcinomas expressed L1. In contrast, only 1 （1.9%） of 54 well-differentiated tumors or carcinomas was positive for LI. No expression was found in Langerhans islet cells of normal pancreatic tissue. Cross table analysis showed a significant association between L1 expression and classification of neuroendocrine tumors of the pancreas （P〈0.01）. CONCLUSION： L1 is specifically expressed in poorlydifferentiated pancreatic neuroendocrine carcinomas that are known to have the worst prognosis. L1 might be a marker for risk prediction of patients diagnosed with pancreatic neuroendocrine carcinomas.

关键词： Neuroendocrine pancreatic tumor Tumor markers Cell adhesion molecules L1

Over-the-scope clip closure of two chronic fistulas after gastric band penetration

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World Journal of Gastroenterology 2010年第13期16卷 1665-1669页

作者： Federico Iacopini Nicola Di Lorenzo Fabrizio Altorio Marc-Oliver schurr Agostino Scozzarro Gastroenterology and Endoscopy Unit Ospedale San Giuseppe Albano Laziale Department of Surgical Science Policlinico Università di Tor Vergata Steinbeis University Berlin IHCI-Institute

Gastrointestinal perforations are conservatively managed at endoscopy by through-the-scope endoclips and covered self expandable stents, according to the size and tissue features of the perforation. This is believed to be the first report of successful closure of two gastrocutaneous fistulas with over-the-scope clips (OTSCs). After laparoscopic gastric banding, a 45-year old woman presented with band erosion and penetration. Despite surgical band removal and gastric wall suturing, external drainage of enteric material persisted for 2 wk, and esophagogastroduodenoscopy demonstrated two adjacent 10-mm and 15-mm fistulous orifices at the esophagogastric junction. After cauterization of the margins, the 10-mm fistulous tract was grasped by the OTSC anchor, invaginated into the applicator cap, and closed by a traumatic OTSC. The other 15-mm fistula was too large to be firmly grasped, and a fully-covered metal stent was temporarily placed. No leak occurred during the following 6 wk. At stent removal: the OTSC was completely embedded in hyperplastic overgrowth; the 15-mm fistula significantly reduced in diameter, and it was closed by another traumatic OTSC. After the procedure, no external fistula recurred and both OTSCs were lost spontaneously after 4 wk. The use of the anchor and the OTSC seem highly effective for successful closure of small chronic perforations.

关键词： Gastrointestinal endoscopy Fistula Stent Esophagogastric junction

Closing the Gap: Characterizing Key Factors Leading to the Disparity in Suicide Rates along the Urban-Rural Continuum

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International Journal of Mental Health Promotion 2022年第2期24卷 159-167页

作者： Harrison schurr Andrei Tuluca Beth Bailey College of Medicine Central Michigan UniversityMount PleasantMI 48859USA

Suicide is a top ten cause of mortality in the United *** previous literature the suicide rates in rural com-munities have been reported to be greater than those of more urban ***,these studies have discussed many potential causes for the unfortunate disparity in *** cause often discussed is lack of mental health care providers in rural *** data for this study was gathered from the CDC’s WONDER data-base and the NPPES NPI *** urban-rural categorization of counties used the 2013 NCHS Urban-Rural *** analysis included chi-square tests,paired t-tests,and stepwise regression *** indi-cate that both the number of residents per provider(r=0.35,p≤0.005),and urbanization level(r=0.49,p≤0.001)were signiﬁcantly related to suicide ***,even after controlling for provider rates,each additional level of rurality predicted an increase of 1.2 suicides per 100,000 ***,the number of providers may play a major role in suicide rates,but extra effort must also be made in rural communities to combat the other contextual factors leading to increased suicide rates.

关键词： Suicide mental health care providers rurality mental health

Oxygen radical formation does not have an impact in the treatment of severe acute experimental pancreatitis using free cellular hemoglobin

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World Journal of Gastroenterology 2006年第18期12卷 2914-2918页

作者： Helge Kleinhans Oliver Mann Paulus G schurr Jussuf T Kaifi Bente Hansen Jakob R Izbicki Tim Strate Department of General- Visceral- and Thoracic SurgeryUniversity Medical Center Hamburg-EppendorfMartinistrasse 52D-20246 HamburgGermany

AIM： Microcirculatory dysfunction and free oxygen radicals are important factors in the pathogenesis of severe acute pancreatitis. Additional oxygen delivery might enhance lipid peroxidation but may also improve pancreatic microcirculation. This study assesses the effect of free cellular bovine hemoglobin on the formation of oxygen radicals and microcirculation in a rodent model of severe acute pancreatitis. METHODS： Fifteen minutes after induction of acute pancreatitis Wistar rats received either 0.8 mL bovine hemoglobin （HBOC-200）, hydroxyethyl starch （HES） or 2.4 mL of normal saline to ensure normovolemic substitution. After 6 h of examination the pancreas was excised and rapidly processed for indirect measurement of lipid peroxidation products malondialdehyde （MDA） and reduced glutathione （GSH） in pancreatic tissue. RESULTS： The single application of HBOC-200 improved pancreatic microcirculation and reduced histopathological tissue damage significantly. Tissue concentration of MDA did not differ between the groups. Also no differences in GSH levels were detected.CONCLUSION： Though the single application of HBOC-200 and HES improve pancreatic microcirculation, no differences in lipid peroxidation products were detected. The beneficial effect of additional oxygen supply （HBOC-200） does not lead to enhanced lipid peroxidation.

关键词： Hemoglobin-based-oxygen-carrier HBOC Blood substitudes Severe acute pancreatitis Free oxygen radicals Oxidative stress

Effects of seed morphology and orientation on secondary seed dispersal by wind

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Journal of Plant Ecology 2022年第6期15卷 1257-1272页

作者： Jinlei Zhu Carsten M.Buchmann Frank M.schurr Institute of Landscape and Plant Ecology University of Hohenheim70599 StuttgartGermany

Understanding how diaspore(hereafter‘seed’)morphology and orientation affect secondary seed dispersal by wind is important to link seed dispersal and post-dispersal processes,such as seed lodging,predation and *** study aims to describe the effects of seed morphology and orientation on secondary seed dispersal by wind via mechanistic *** extend the mechanistic model of schurr et al.(2005)in order to describe how secondary seed dispersal by wind is affected by wind conditions,ground surface,seed morphology and *** model simulates the initial landing orientations,dispersal distances and stopping orientations of individual *** parameterize the model,we measured orientation-specific vertical seed projection and seed lift-off velocity(the wind speed at which a seed starts moving on the ground)of the asymmetric seeds of heterocarpous Zygophyllum xanthoxylon,and determined orientation-specific model parameters that depend on properties of seeds and/or the *** validate the model,we conducted wind channel experiments in which we released seeds of *** onto a sand-coated tar paper,and recorded the initial landing orientations,dispersal distances and stopping orientations of the *** extended model could precisely predict secondary dispersal distance,and explain up to 99%of variation in the observed proportions of seeds which stopped in various *** model predicts that secondary dispersal distance increases with wind speed and decreases with aerodynamic roughness length,and that there might be a positive correlation between dispersal distance and germination success.

关键词： Zygophyllum xanthoxyllon heterodiaspory mechanistic modelling phase II dispersal seed orientation tumbleweed winged seed

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麻风的遗传学

中国麻风杂志 1994年第1期10卷 54-57页

作者： E schurr 江蜀利

对麻风菌的易感性是一复合表型,可能受细菌、宿主和环境因素的影响,但后两种因素的重要性尚难以确定。调查发现遗传因素对易感性起主要作用。许多人研究了麻风的遗传学,以确定遗传因子是否控制麻风的易感性及其临床类型,并试图将这些遗... 详细信息

对麻风菌的易感性是一复合表型,可能受细菌、宿主和环境因素的影响,但后两种因素的重要性尚难以确定。调查发现遗传因素对易感性起主要作用。许多人研究了麻风的遗传学,以确定遗传因子是否控制麻风的易感性及其临床类型,并试图将这些遗传因子定位到人类基因组的不同区域。

关键词：麻风遗传学病理

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真实的“虚拟计划”

电子与电脑 1995年第10期2卷 110-114页

作者： Amy schurr 张翀

共享介质局域网技术将成为过去,未来属于虚拟网络(VLAN),这种趋势会越来越明显。一个VLAN是逻辑地建立的——基于我们的实际需要的基础之上,而不再局限于地理位置。这样一个有说服力的结构消除了物理网络的限制和开销大等问题。为了帮... 详细信息

共享介质局域网技术将成为过去,未来属于虚拟网络(VLAN),这种趋势会越来越明显。一个VLAN是逻辑地建立的——基于我们的实际需要的基础之上,而不再局限于地理位置。这样一个有说服力的结构消除了物理网络的限制和开销大等问题。为了帮助那些终日忙碌于产品说明的信息技术负责人,我们向四大网络厂商了解了它们各自的交互网络策略和产品交付时间: ·Bay Networks的BaySIS,见图1; ·Cabletron的Synthesis,见图2;

关键词：虚拟网络局域网络 ATM