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Sero-Prevalence of Brucellosis among Nomadic Herdsmen, Abattoir and Livestock Workers in Niger-Delta Region, Nigeria

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Journal of Biosciences and Medicines 2019年第10期7卷 32-41页

作者： Etanguno effiong Owowo ukponobong effiong antia Mary Anthony Christopher Iquo effiong Okon Department of Microbiology Akwa Ibom State University Mkpat Enin Nigeria Health Initiative for Stability & Safety in Africa (HIFASS) Uyo Nigeria

Brucellosis is a reemerging zoonotic disease that causes more than half a million infections to humans every year. The disease is common in most developing countries, the human mortality rate is about 2%, and the disease causes severe rheumatism, infertility in males, spontaneous abortion and also results in wastage of resources through prolonged treatment. Brucella organisms are also potential biological weapon which could be cheaper to produce but more devastating than chemical weapons. About 5 mililitres of blood was drawn from 228 subjects using sterile vacutainers and analyzed by using standard tube agglutination tests: (SAT3 160) and ELISA (IgG, IgM) kits specific for Brucella abortus and Brucella melitensis antibodies. Semi structured questionnaire was administered to collect data. In the study, overall sero prevalence was 70 (30.8%). More male participated in the study with a frequency of 24.6% of whom 7.92% falls within the age group of 20 to 30, followed by 31 - 35 years with 5.72% and 3.52% within 36 - 45 years. Least affected were those in the age groups above 46 years (2.20%). Approximately, 21.54% of the subjects had formal education either at Quranic, primary and secondary or tertiary level. Majority acquired Quranic education (9.68%), 7.48% primary and 0.88% had tertiary training. A total of 21 (9.24%) never acquired any form of education. Headache, muscle aches, malaise, chills and fatigue were the most common clinical signs and symptoms experienced by about 30% among the participants. In the distribution of Brucella antibodies, ELISA diagnostic kits showed high sensitivity with the prevalence rate of 18.04% (n = 41) followed by SAT 12.76% (n = 29). The sensitivity and specificity of RDPT kits were 37 % and 69%, with a positive and negative predictive value of 18% and 86% respectively. Unprocessed milk from the market and consumption of unboiled milk were associated with brucellosis. Therefore, patients with brucellosis should be treated to prevent

关键词： Brucella Zoonotic Nomadic Herdsmen Rapid Brucella Diagnostic Kits Nigeria

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Prevalence of <i>Helicobacter pylori</i>Infection among Internally Displaced Persons from Bakassi Peninsular and Etim Ekpo in South Southern, Nigeria

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Journal of Biosciences and Medicines 2019年第9期7卷 28-37页

作者： Etanguno effiong Owowo Mary Anthony Christopher Iquo effiong Okon ukponobong effiong antia Veronica Umoh Department of Microbiology Akwa Ibom State University Mkpat-Enin Nigeria Health Initiative for Stability & Safety in Africa (HIFASS) Uyo Nigeria

Helicobacter pylori (H. pylori), is an important global infection with a worldwide prevalence of about 40 percent. This infection is contagious and mostly acquired during childhood through the fecal-oral and oral-oral route. A total of 1560 blood specimens were aseptically collected from Internally Displaced Persons comprising female and male from the warring communities of Bakassi Peninsular and Etim Ekpo Local Government Area in South Southern, Nigeria. The specimens were screened for H. pylori using Elisa kits following standard serological techniques. The overall prevalence rate was 464 (29.7%). There was significant difference (p H. pylori infection;its distribution varied between age group, educational status, habits or behaviors of the subjects with children within 5 to 14 years having the highest rate of 274 (17.6%), followed by 78 (4.99%) from adults (51 years and above) and 17 (1.08%) from active age range of 36 - 45 years old. Subjects with primary and quranic level of education showed a total of 274 (17.56%) positive cases to H. pylori. Analysis of sex-specific distribution revealed that females had the highest prevalence of 312 (20%). The helicobacter infection shows a significant difference at (p H. pylori infection. Crowding in camps and increasing household contact have been considered as risk factors of H. pylori infection. Adequate infrastructural provision and availability of portable water with good hygienic environment will drastically reduce the high rate spread of H. pylori bacterium in the IDPs communities in Nigeria.

关键词： Helicobacter pylori Internally Displaced Persons Camp

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