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Application of ultrasonography-elastography score to suspect porto-sinusoidal vascular disease in patients with portal vein thrombosis

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Hepatobiliary & Pancreatic Diseases International 2024年第1期23卷 20-24页

作者： Stefania Gioia Adriano De Santis Giulia d’Amati Silvia Nardelli Alessandra Spagnoli Arianna Di Rocco Lorenzo Ridola oliviero Riggio Department of Translational and Precision Medicine Sapienza University of RomeRomeItaly Department of Radiological Oncologicaland Pathological SciencesSapienza University of RomeRomeItaly Department of Public Health and Infectious Diseases Sapienza University of RomeRomeItaly

Background:Porto-sinusoidal vascular disease(PSVD)and portal vein thrombosis(PVT)are causes of portal hypertension characterized respectively by an intrahepatic and a pre-hepatic obstacle to the flow in the portal *** PVT may be a consequence of PSVD,in PVT patients at presentation,a pre-existing PSVD should be *** these patients the identification of an underlying PSVD would have relevant implication regarding follow-up and therapeutic management,but it could be *** this setting ultrasonography may be valuable in differential *** aim of the study was to use ultrasonography to identify parameters to discriminate between PSVD and“pure”PVT and then to suspect PVT secondary to a pre-existing ***:Fifty-three patients with histologically proven PSVD and forty-eight patients affected by chronic PVT were enrolled and submitted to abdominal ultrasonography with elastography by acoustic radiation force impulse(ARFI).Results:ARFI was higher and superior mesenteric vein(SMV)diameter was wider in PSVD patients than in PVT ***,a prognostic score was obtained as linear combinations of the two parameters with a good discrimination capacity between PSVD and PVT(the area under the curve=0.780;95%confidence interval:0.690-0.869).Conclusions:A score based on ARFI and SMV diameter may be useful to suspect an underlying PSVD in patients with PVT and to identify a subgroup of patients to be submitted to liver biopsy.

关键词： Non-cirrhotic portal hypertension Porto-sinusoidal vascular disease Chronic portal vein thrombosis Liver stiffness Portal hypertension Acoustic radiation force impulse

Impaired diastolic function in nave untreated human immunodeficiency virus infected patients

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World Journal of Cardiology 2010年第4期2卷 98-103页

作者： ugo oliviero Giovanni Bonadies Giorgio Bosso Maria Foggia Valentina Apuzzi Mariarosaria Cotugno Antonio Valvano Enrico Leonardi Guglielmo Borgia Giuseppe Castello Raffaele Napoli Luigi Saccà Department of Inter-nal Medicine University Federico Ⅱ80131 NaplesItaly Department of Infectious Diseases University Federico Ⅱ80131 NaplesItaly National Cancer Institute G.Pascale Foundation80131 NaplesItaly

AIM:To evaluate cardiac function and structure in un-treated human immunodeficiency virus(HIV) patients without clinical evidence of cardiovascular ***:Fifty-three nave untreated HIV-infected patients and 56 healthy control subjects underwent clinical assessment,electrocardiography(ECG) and echocardiography,including tissue doppler ***,a set of laboratory parameters was obtained from all subjects,including HIV-RNA plasma levels,CD4 cell counts and tumor necrosis factor-α ***:The two groups showed normal ECG traces and no differences regarding systolic morphologic *** contrast,a higher prevalence of left ventricular diastolic dysfunction(abnormal relaxation or pseudonormal filling pattern) was found in the HIV patients(36% vs 9% in patients and controls,respec-tively,P <0.001).CONCLUSION:Subclinical cardiac abnormalities ap-pear in an early stage of the HIV infection,indepen-dent of antiretroviral *** data suggest that HIV per se plays a role in the genesis of diastolic dys-function.

关键词： Diastolic function Human immunodeficiency virus Naive subjects Cardiovascular risk factors

Management of chronic heart failure:Role of home echocardiography in monitoring care programs

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World Journal of Cardiology 2012年第3期4卷 72-76页

作者： Silvia Soreca Sergio Aprile Andrea Cardone Giovanni Carella Biagio Fimiani Franco Guarnaccia Giosuè Santoro Valentina Apuzzi Giorgio Bosso Antonio Valvano Giovanni Zito ugo oliviero Associazioni Regionali Cardiologi Ambulatoriali CampaniaVia M.Testa 884127 SalernoItaly Department of Clinical Medicine and Cardiovascular Sciences Federico Ⅱ UniversityVia S.Pansini 580131 NaplesItaly

AIM:To identify a possible role of home echocardiography for monitoring chronic heart failure(CHF)***:We prospectively investigated 118 patients hospitalized during the last year for CHF who could not easily reach the pertaining District Healthcare *** patients were followed up with 2 home management programs:one including clinical and electrocardiographic evaluations and also periodic home echocardiographic examinations(group A),the other including clinical and electrocardiographic evaluations only(group B).RESULTS:At the end of the 18-mo follow-up no significant differences were observed between the 2 groups as regards the primary endpoint:rehospitalization occurred in 4 patients of the group A and in 6 patients of the group B;major cardiovascular events occurred in 2 and in 3 patients,*** significant differences were observed with respect to the secondary endpoints:one vascular event appeared in both the groups,3 cardiovascular deaths occurred in group A and 2 in group *** significant differences were observed between the 2 groups as regards the composite endpoint of death plus ***:Home echocardiography for monitoring of CHF patients does not improve the cardiovascular *** our CHF patients,a low incidence of vascular events was observed.

关键词： Echocardiography Chronic heart failure Home monitoring Care programs Cardiovascular events

Recent advances concerning polyurethane in leather applications:an overview of conventional and greener solutions

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Collagen and Leather 2023年第1期5卷 1-15页

作者： Jize Liu Federica Recupido Giuseppe Cesare Lama Maria oliviero Letizia Verdolotti Marino Lavorgna Institute for Polymers Composites and Biomaterials(IPCB-CNR)Piazzale Enrico Fermi 180055 Portici(Naples)Italy

Leather is one of the most popular products across globe and holds a significant place in the economy,while the pollution,associated to traditional leather industry,is far away on the"green chemistry"*** this sense,polyurethanes,which exhibit tunable chemical structures by selecting suitable precursors,can fit specific requirements,and the developments of green strategies make them important candidates for leather *** mini review briefly outlines the recent development of conventional(petrol-based)and sustainable polyurethanes in the leather industry,including their design and properties,in applications such as synthetic leather and surface-finishing(coatings/binders).Finally,outlooks of the future tendency,including more environmental-friendly strategies,bio-sourced/recycled materials and development of high-value multifunctional leather materials,are also here proposed.

关键词： Conventional leather Artificial leather polyurethane-synthetic leather polyurethane-based binders polyurethane-based-materials Polyurethane-based-coatings

Determinants of prognosis in cirrhosis:a new outlook

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Hepatobiliary Surgery and Nutrition 2022年第5期11卷 759-761页

作者： Lorenzo Ridola Stefania Gioia Jessica Faccioli Silvia Nardelli oliviero Riggio Department of Translational and Precision Medicine “Sapienza”University of RomeRomeItaly

The metanalysis by Tantai and collaborators highlights the role of sarcopenia in cirrhosis by demonstrating that the presence of muscular alterations is independently related with a mortality(HR 2.61)(1).Sarcopenia is confirmed as a condition with high prevalence in patients with cirrhosis(37.5%),being more representative in males than females(41.9%vs.37.8%)and in subjects with alcoholic etiology(49.6%)or with more advanced degree of liver disease(Child Pugh C 46.7%).Interestingly,authors demonstrate that sarcopenia was associated with mortality in subjects with MELD15(HR 2.34)as well evaluating only on studies that excluded patients with hepatocellular carcinoma(HCC),risk of mortality was similar to that of the main analysis(2.35)(1).

关键词： cirrhosis mortality alterations

Non-invasive tests for fibrosis detection: still in search for the best way

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Hepatobiliary Surgery and Nutrition 2022年第6期11卷 920-923页

作者： Lorenzo Ridola Danila Capoccia Gloria Guarisco oliviero Riggio Frida Leonetti Department of Translational and Precision Medicine Sapienza University of RomeRomeItaly Department of Medical-Surgical Sciences and Biotechnologies Sapienza University of RomeRomeItaly

Eilenberg and colleagues’paper highlights the importance of non-invasive detection by using vibration controlled transient elastography(VCTE)and controlled attenuation parameter(CAPTM)for the assessment of fibrosis,s... 详细信息

关键词： invasive obesity transient

Ascitic fluid analysis for diagnosis and monitoring of spontaneous bacterial peritonitis

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World Journal of Gastroenterology 2009年第31期15卷 3845-3850页

作者： oliviero Riggio Stefania Angeloni Department of Clinical Medicine "Sapienza" University of Rome

Polymorphonuclear (PMN) cell count in the ascitic fluid is essential for the diagnosis and management of spontaneous bacterial peritonitis (SBP). To date, PMN cell count is routinely performed by traditional manual counting. However, this method is time-consuming, costly, and not always timely available. Therefore, considerable efforts have been made in recent years to develop an alternative test for a more rapid diagnosis and monitoring of SBP. The use of urinary reagent strips was proposed to achieve an "instant" bedside diagnosis of SBP. A series of reports evaluated the urine strip test for SBP diagnosis and reported promising results. However, a recent large multicenter study revealed a surprising lack of diagnostic effi cacy of the urine screening test for SBP diagnosis. Another method, more recently proposed as an alternative to the manual PMN count, is the measurement of lactoferrin in ascitic fluid, but the data available on the diagnostic value of this test are limited to a single study. However, both urinary reagent strips and ascitic lactoferrin tests are qualitative methods and need, therefore, to be further confirmed by standard cytology of the ascitic fluid. To date, the only quantitative method proposed as a valid alternative to manual PMN counting is automated blood cell counters, commonly used in all laboratories for blood cell counting. Data available in the literature on the diagnostic performance of this method are limited but very promising, and this tool seems to have the potential to replace the manual counting method.

关键词：腹膜炎细菌性水分析监测诊断

Fabulous Glamping Destinations in Georgia

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空中英语教室（高级版．彭蒙惠英语） 2022年第5期 11-13,40,41页

作者： Helena oliviero 徐佩仪(译) 不详

现在正是享受户外的美好季节一外出踏青、烤棉花糖,也许睡在星空下也很宜人:对于想要摆脱电子产品而重新投入大自然怀抱,却又(丝毫)不想吃苦头的人而言,“豪华露营”也许正投其所好:佐治亚州有若干个目的地可以让你依偎在大自然的怀抱,... 详细信息

现在正是享受户外的美好季节一外出踏青、烤棉花糖,也许睡在星空下也很宜人:对于想要摆脱电子产品而重新投入大自然怀抱,却又(丝毫)不想吃苦头的人而言,“豪华露营”也许正投其所好:佐治亚州有若干个目的地可以让你依偎在大自然的怀抱,又不必牺牲家的舒适。下面就来看看其中四个景点:奇克莫加的烛光森林树屋。

关键词：佐治亚州棉花糖投其所好电子产品

Controlling infestation of a chocolate factory by Plodia interpunctella by combining mating disruption and the parasitoid Habrobracon hebetor

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Insect Science 2017年第3期24卷 503-510页

作者： Pasquale Trematerra Annachiara oliviero Sara Savoldelli Matthias Scholler Department of Agricultural Environmental and Food Sciences University of Molise Via De Sanctis 86100 Campobasso Italy Department of Food Environmental and Nutritional Sciences Universit& degli Studi di Milano Via Celoria 2 20133 Milan Italy Faculty of Life Sciences Humboldt-Universit#t zu Berlin Lentzeallee 55/57 14195 Berlin Germany

A field experiment of 4 years＇ duration was carried out to evaluate the ef- ficacy of combining the mating disruption （MD） formulation Dismate ZETA （（9Z,12E）- tetradecadienyl acetate）, with the parasitoid Habrobracon hebetor against the Indianmeal moth Plodia interpunctella in a chocolate factory. The experimental period began early in 2011 and ended in late 2014. Begane Dismate dispensers were placed in the facility from 2011 to 2014 and H. hebetor was released in 2014. Pheromone-baited traps were used to monitor the flight activity of the male moths and oviposition Petri dish traps were placed to assess the progeny production ofP. interpunctella females. Following the start of MD, a decrease in the number ofP. interpunctella males caught in monitoring traps was observed from 2011 to 2013. A further decline in the moth population was noted in 2014, when MD was combined with the release of parasitoids. The presence of larvae in the oviposition cups was occasionally observed throughout the monitoring period, from 2011 to 2014. This study demonstrates that the combined system of MD and parasitoids is an effective and reliable technique that can be used to successfully control P. interpunctella.

关键词： control food processing integrated pest management mating disruption parasitoid Plodia interpunctella