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Copper Ameliorates Fluoride Toxicity in Fluoride and Molybdenum Fed Rabbits

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Biomedical and Environmental Sciences 2013年第4期26卷 311-313页

作者： Arjun L KHANDARE uday kumar Priyanka SHANKAR Shanker RAO Food and Drug Toxicology Centre National Institute of NutritionIndian Council of Medical ResearchPOJama-I-OsmaniaHyderabad-500007Andhra PradeshIndia Department of Pathology National Institute of NutritionHyderabadIndia

Hydrofluorosis is a major public health problem in India, which is aggravated by presence or absence of some minerals in water or food. Fluoride by itself or in combination with other elements like molybdenum （Mo） in diet or water changes excretion/retention of bone minerals. Sorghum and pearl millet grown and consumed in fluorosis endemic areas contained significantly higher amounts of Mo than that grown in non-fluorotic areas in India.

关键词： Copper Ameliorates Fluoride Toxicity in Fluoride and Molybdenum Fed Rabbits body

Recharge and vulnerability assessment of groundwater resources in North west India:Insights from isotope-geospatial modelling approach

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Geoscience Frontiers 2024年第1期15卷 247-262页

作者： Annadasankar Roy Sitangshu Chatterjee uday kumar Sinha Anil kumar Jain Hemant Mohokar Ajay Jaryal Tirumalesh Keesari Harish Jagat Pant Isotope and Radiation Application Division Bhabha Atomic Research CentreTrombayMumbai–400085India Homi Bhabha National Institute Mumbai 400094India Central Ground Water Board AhmedabadGujaratIndia

Recent studies indicate dwindling groundwater quantity and quality of the largest regional aquifer system in North West India,raising concern over freshwater availability to about 182 million population residing in this *** agricultural activities have resulted severe groundwater pollution in this area,demanding a systematic vulnerability assessment for proactive *** vulnerability assessment models encounter drawbacks due to subjectivity,complexity,data-prerequisites,and spatial-temporal *** study incorporates isotopic information into a weighted-overlay framework to overcome the above-mentioned limitations and proposes a novel vulnerability assessment *** isotope methodology provides crucial insights on groundwater recharge mechanisms(18O and 2H)and dynamics(3H)-often ignored in vulnerability *** characterisation of precipitation helped in establishing Local Meteoric Water Line(LMWL)as well as inferring contrasting recharge mechanisms operating in different *** aquifer(depth<60 m)showed significant evaporative signature with evaporation loss accounting up to 18.04%based on Rayleigh distillation ***-aquifer connections were apparent from Kernel Density Estimate(KDE)and isotope correlations.A weighted overlay isotope-geospatial model was developed combining 18O,3H,aquifer permeability,and water level *** central and northern parts of study area fall under least(0.29%)and extremely(1.79%)vulnerable zones respectively,while majority of the study area fall under moderate(42.71%)and highly vulnerable zones(55.20%).Model validation was performed using groundwater NO3-concentration,which showed an overall accuracy up to 82%.Monte Carlo Simulation(MCS)was performed for sensitivity analysis and permeability was found to be the most sensitive input parameter,followed by 3H,18O,and water *** the vulnerability map with Land Use Land Cover(LULC)and population density maps

关键词： Agricultural pollution Data scarcity Recharge mechanism Rayleigh distillation Isotope-geospatial model Vulnerability assessment

Reliability and maintainability analysis of electrical system of drum shearers

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Journal of Coal Science & Engineering(China) 2011年第2期17卷 192-197页

作者： SEYED Hadi Hoseinie MOHAMMAD Ataei REZA Khalokakaie uday kumar Faculty of Mining Petroleum ＆ Geophysics Shahrood University of Technology Shahrood *** Iran Division of Operation and Maintenance Engineering Lulea University of Technology Lulea 97187 Sweden

The reliability and maintainability of electrical system of drum shearer at Parvade. 1 Coal Mine in central Iran was analyzed. The maintenance and failure data were collected during 19 months of shearer operation. According to trend and serial correlation tests, the data were independent and identically distributed （iid） and therefore the statistical techniques were used for modeling. The data analysis show that the time between failures （TBF） and time to repair （TTR） data obey the lognormal and Weibull 3 parameters distribution respectively. Reliability-based preventive maintenance time intervals for electrical system of the drum shearer were calculated with regard to reliability plot. The reliability-based maintenance intervals for 90%, 80%, 70% and 50% reliability level are respectively 9.91, 17.96, 27.56 and 56.1 h. Also the calculations show that time to repair （TTR） of this system varies in range 0.17-4 h with 1.002 h as mean time to repair （MTTR）. There is a 80% chance that the electrical system of shearer of Parvade. 1 mine repair will be accomplished within 1.45 h.

关键词： drum shearer electrical system reliabilitv maintenance

Reliability modeling of hydraulic system of drum shearer machine

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Journal of Coal Science & Engineering(China) 2011年第4期17卷 450-456页

作者： SEYED HADI Hoseinie MOHAMMAD Ataie REZA Khalookakaei uday kumar Faculty of Mining Petroleum ＆ Geophysics Shahrood University of Technology Shahrood *** Iran Division of Operation and Maintenance Engineering Lulea University of Technology Lulea 97187 Sweden

The hydraulic system plays an important role in supplying power and its transition to other working parts of a coal shearer machine. In this paper, the reliability of the hydraulic system of a drum shearer was analyzed. A case study was done in the Tabas Coal Mine in Iran for failure data collection. The results of the statistical analysis show that the time between failures （TBF） data of this system followed the 3-parameters Weibull distribution. There is about a 54% chance that the hydraulic system of the drum shearer will not fail for the first 50 h of operation. The developed model shows that the reliability of the hydraulic system reduces to a zero value after approximately 1 650 hours of operation. The failure rate of this system decreases when time increases. Therefore, corrective maintenance （run-to-t^ailure） was selected as the best maintenance strategy for it.

关键词： reliability modeling hydraulic system drum shearer maintenance strategy

Assembling structurally customizable synthetic carriers of si RNA through thermodynamically self-regulated process

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Asian Journal of Pharmaceutical Sciences 2020年第3期15卷 356-364页

作者： Guang Bai Tong Xue Xiaotao Dong uday kumar Chinta Jia Feng Tuo Jin Fei Wu School of Pharmacy Shanghai Jiao Tong UniversityShanghai 200240China

This study demonstrates that our previously reported polywraplex, a synthetic siRNA carrier consisting of a uni-molecular polyplex core of customizable size and a self-assembled triblock copolymer envelop, may be constructed using dendrimers as the crosslinking junctions. Replacing the branched low molecular weight PEI with polyamidoamine(PAMAM) dendrimer in the zeta potential regulated polymerization resulted in the similar network structured cationic polymer with electron microscopically visible crosslinking junctions. This visibility may offer a convenient way to characterize the molecular structure of the rationally designed networked siRNA-packing cationic polymer without altering its chemical properties and biologic functions. A series of physical-chemical characterizations and biological assays, comprising size, zeta potential, pre-phagocytic siRNA leaking and degradation, and silencing of functional genes, confirmed that the advanced properties of polywraplexes remained with the dendrimer junctions. Although sixth generation PAMAM dendrimer was used as the crosslinking junctions in the size-customizable polymerization for electron microscopic observation, lower generation dendrimer should also work in case more practical and structurally defined cationic polymer is needed.

关键词： Networked cationic polymer Thermodynamically self-regulated processes siRNA delivery Unimolecular polyplex Zeta potential regulated polymerization

IN2CLOUD: A novel concept for collaborative management of big railway data

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Frontiers of Engineering Management 2017年第4期4卷 428-436页

作者： Jing LIN uday kumar Division of Operation and Maintenance Engineering Lulea University of Technology Lulea 97187 Sweden Lulea Railway Research Centre (JVTC) Lulea 97187Sweden

In the EU Horizon 2020 Shift2Rail MultiAnnual Action Plan, the challenge of railway maintenance is generating knowledge from data and/or information. Therefore, we promote a novel concept called"IN2CLOUD," which comprises three sub-concepts, to address this challenge: 1) A hybrid cloud, 2) an intelligent cloud with hybrid cloud learning, and 3) collaborative management using asset-related data acquired from the intelligent hybrid cloud. The concept is developed under the assumption that organizations want/need to learn from each other(including domain knowledge and experience)but do not want to share their raw data or ***2CLOUD will help the movement of railway industry systems from "local" to "global" optimization in a collaborative way. The development of cutting-edge intelligent hybrid cloud-based solutions, including information technology(IT) solutions and related methodologies, will enhance business security, economic sustainability, and decision support in the field of intelligent asset management of railway assets.

关键词： railway intelligent asset management collaborative learning big data hybrid cloud Bayesian

Integrated Approach of Universal Soil Loss Equation (USLE) and Geographical Information System (GIS) for Soil Loss Risk Assessment in Upper South Koel Basin, Jharkhand

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Journal of Geographic Information System 2012年第6期4卷 588-596页

作者： Reshma Parveen uday kumar University Department of Geology Ranchi University Ranchi India

Soil erosion is a growing problem especially in areas of agricultural activity where soil erosion not only leads to decreased agricultural productivity but also reduces water availability. Universal Soil Loss Equation (USLE) is the most popular empirically based model used globally for erosion prediction and control. Remote sensing and GIS techniques have become valuable tools specially when assessing erosion at larger scales due to the amount of data needed and the greater area coverage. The present study area is a part of Chotanagpur plateau with undulating topography, with a very high risk of soil erosion. In the present study an attempt has been made to assess the annual soil loss in Upper South Koel basin using Universal Soil Loss Equation (USLE) in GIS framework. Such information can be of immense help in identifying priority areas for implementation of erosion control measures. The soil erosion rate was determined as a function of land topography, soil texture, land use/land cover, rainfall erosivity, and crop management and practice in the watershed using the Universal Soil Loss Equation (for Indian conditions), remote sensing imagery, and GIS techniques. The rainfall erosivity R-factor of USLE was found as 546 MJ mm/ha/hr/yr and the soil erodibility K-factor varied from 0.23 - 0.37. Slopes in the catchment varied between 0% and 42% having LS factor values ranging from 0 - 21. The C factor was computed from NDVI (Normalized Difference Vegetative Index) values derived from Landsat-TM data. The P value was computed from existing cropping patterns in the catchment. The annual soil loss estimated in the watershed using USLE is 12.2 ton/ha/yr.

关键词： Universal Soil Loss Equation (USLE) Remote Sensing & GIS Soil Loss

Composite indicator for railway infrastructure management

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Journal of Modern Transportation 2014年第4期22卷 214-224页

作者： Stephen M.Famurewa Christer Stenstrm Matthias Asplund Diego Galar uday kumar Division of Operation and Maintenance Engineering Lule University of Technology Lule Sweden Lule Railway Research Centre Lule Sweden Trafikverket (the Swedish Transport Administration) LuleSweden

The assessment and analysis of railway infra structure capacity is an essential task in railway infra structure management carried out to meet the required quality and capacity demand of railway transport. For sustainable and dependable infrastructure management, it is important to assess railway capacity limitation from the point of view of infrastructure performance. However, the existence of numerous performance indicators often leads to diffused information that is not in a format suitable to support decision making. In this paper, we demonstrated the use of fuzzy inference system for aggregating selected railway infrastructure performance indicators to relate maintenance function to capacity situation. The selected indicators consider the safety, comfort, punctuality and reliability aspects of railway infrastructure performance. The resulting composite indicator gives a reliable quanti fication of the health condition or integrity of railway lines. A case study of the assessment of overall infrastructure performance which is an indication of capacity limitation is presented using indicator data between 2010 and 2012 for five lines on the network of Trafikverket （Swedish Trans port Administration）. The results are presented using cus tomised performance dashboard for enhanced visualisation,quick understanding and relevant comparison structure conditions for strategic management. This gives additional information on capacity status and limitation from maintenance management perspective.

关键词： Composite indicator Infrastructure capacityFuzzy logic Performance dashboard Strategic decisionsLine integrity

Geomorphometric Characterization of Upper South Koel Basin, Jharkhand: A Remote Sensing &GIS Approach

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Journal of Water Resource and Protection 2012年第12期4卷 1042-1050页

作者： Reshma Parveen uday kumar Vivek kumar Singh Department of Geology & Mining CIAL Abhijeet Group Nagpur India Department of Geology Ranchi University Ranchi India

The quantitative analysis of drainage system is an important aspect of characterization of watersheds. Morphometry is measurement and mathematical analysis of landforms. The present study is an attempt to evaluate the drainage morphometrics of Upper South Koel Basin using Remote Sensing and GIS approach. A morphometric analysis was carried out to describe the topography and drainage characteristics of Upper South Koel watershed. The stream numbers, orders, lengths and other morphometric parameters like bifurcation ratio, drainage density, stream frequency, shape parameters etc. were measured. The drainage area of Upper South Koel watershed is 942.4 sq km and the drainage pattern is dentritic. The watershed was classified as 6th order drainage basin. The low values of bifurcation ratio and drainage density suggest that the area has not been much affected by structural disturbances. The study reveals that the different geomorphic units in the study area i.e. Structural hills, Pediments, Valley fills, Pediplains formed under the influence of permeable geology, are moderate to nearly level plains, with medium to low drainage density (<2.0) & low cumulative length of higher order streams . Such studies can be of immense help in planning and management of river basins.

关键词： Morphometry Watershed Remote Sensing GIS