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Antimicrobial drug resistance of Staphylococcus aureus in dairy products

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Asian Pacific Journal of Tropical biomedicine 2011年第2期1卷 130-132页

作者： Sasidharan S Prema b Yoga Latha L Institute for Research in Molecular Medicine(INFORMM) Universiti Sains Malaysia Department of biotechnology Faculty of Applied SciencesAIMST UniversityJalan Bedong-SemelingBatu 3 1/2Bukit Air Nasi

Objective:To evaluate the prevalence of multidrug resistant Staphylococcus aureus(***) in dairy ***:Isolation and identification of *** were performed in 3 dairybased food *** isolates were tested for their susceptibility to 5 different common antimicrobial ***:Of 50 samples examined,5(10%) were contaminated with 5. ***,the 5 isolates were subjected to antimicrobial resistance pattern using five antibiotic discs(methicillin,vancomycin,kanamycin,chloramphenicol and tetracycline).Sample 29 showed resistance to methicillin and *** 18 showed intermediate response to *** other samples were susceptible to all the antibiotics ***:The results provide preliminary data on sources of food contamination which may act as vehicles for the transmission of antimicrobial-resistant ***,it enables us to develop preventive strategies to avoid the emergence of new strains of resistant ***.

关键词： Antimicrobial drug resistance Staphylococcus aureus Milk Dairy product

Optimal control and cost-effective analysis of the 2017 meningitis outbreak in Nigeria

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Infectious Disease Modelling 2019年第1期4卷 161-187页

作者： F.b.Agusto M.C.A.Leite Department of Ecology&Evolutionary biology University of KansasLawrenceKSUnited States Mathematics and Statistics unit University of South Florida at St.PetersburgFLUnited States

This paper presents a deterministic model for Neisseria meningitidis,a bacterium that causes *** model was parameterized using data from the 2017 meningitis outbreak in *** control theory was applied to investigate the optimal strategy for curtailing the spread of the disease using control variables determined from sensitivity *** control variables are personal-protection such as the use of facial masks,and *** results show that the two controls avert more infections at low ***,a reciprocal relationship exists between the use of facial masks and *** is,when the use of facial masks is high,the use of vaccine is low and vice ***-effective analysis was applied to investigate the most cost-effective strategy from various combination of control *** results show that strategy combining all the control variables is the most cost-effective strategy followed by the strategy involving both personal-protection,the vaccination-only strategy was the least *** vaccination strategy is not cost-effective in this study,it is as effective in curtailing the infection as the other two control *** study suggests that governments of communities with limited resources should consider complementing the use of vaccine with the use of facial mask particularly in hard-to-reach places in their communities.

关键词： Neisseria meningitidis Sensitivity analysis Optimal control Cost-effective analysis

Point-of-care testing in the diagnosis of gastrointestinal cancers: Current technology and future directions

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World Journal of Gastroenterology 2015年第14期21卷 4111-4120页

作者： Jeremy R Huddy Melody Z Ni Sheraz R Markar George b Hanna Department of Surgery and Cancer Imperial College LondonSt Mary’s Hospital

Point-of-care(POC) tests enable rapid results and are well established in medical *** advances in analytical techniques have led to a new generation of POC devices that will alter gastrointestinal diagnostic *** review aims to identify current and newtechnologies for the POC diagnosis of gastrointestinal cancer.A structured search of the Embase and Medline databases was *** reporting diagnostic tests for gastrointestinal cancer available as a POC device or containing a description of feasibility for POC application were *** recovered were heterogeneous and therefore results are presented as a narrative *** diagnostic methods were identified(fecal occult blood, fecal proteins, volatile organic compounds, pyruvate kinase isoenzyme type M2, tumour markers and DNA analysis).Fecal occult blood testing has a reported sensitivity of 66%-85% and specificity greater than 95%.The others are at a range of development and clinical *** devices have a proven role in the diagnosis of gastrointestinal *** to their implementation exist and the transition from experimental to clinical medicine is currently *** technologies demonstrate potential to provide accurate POC tests and an ability to diagnose gastrointestinal cancer at an early stage with improved clinical outcome and survival.

关键词： Colorectal cancer Cancer-diagnosis Gastric cancer

Cementing mechanism of algal crusts from desert area

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Chinese Science bulletin 2002年第16期47卷 1361-1368页

作者： Hu Chunxiang LIu Yongding ZHANG Delu HuANG Zebo b.S.Paulsen College of Life Sciences Northwest Normal UniversityLanzhou 730070China Institute of Hydrobiology Chinese Academy of SciencesWuhan 430072China School of Pharmacy University of Oslo1068 BlindemN-0316 OsloNorway

34-, 17-, 4-, 1.5-year old natural algal crusts were collected from Shapotou Scientific Station of the Chinese Academy of Sciences, 40-day old field and greenhouse artificial algal crusts were in situ developed in the same sandy soil and the same place (37°27’N, 104°57’E). Their different cohesions both against wind force and pressure were measured respectively by a sandy wind-tunnel experiment and a penetrometer. On the basis of these algal crusts, the cementing mechanism was revealed from many subjects and different levels. The results showed that in the indoor artificial crusts with the weakest cohesion bunchy algal filaments were distributed in the surface of the crusts, produced few extracellular polymers (EPS), the binding capacity of the crusts just accomplished by mechanical bundle of algal filaments. For field crusts, most filaments grew toward the deeper layers of algal crusts, secreted much more EPS, and when organic matter content was more than 2.4 times of chlorophyll a, overmuch organic

关键词： algal crust cohesion cementing structure gluing sub-stance cementing mechanism EPS.

Total dysphagia after short course of systemic corticotherapy:Herpes simplex virus esophagitis

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World Journal of Gastroenterology 2013年第31期19卷 5178-5181页

作者： Isa Jetté-Cté Denise Ouellette Claire béliveau Andrew Mitchell Division of Thoracic Surgery Maisonneuve-Rosemont Hospital University of MontrealMontreal H3L 2H8 Canada Department of Infectious Diseases and Microbiology Maisonneuve-Rosemont Hospital University of MontrealMontreal H3L 2H8 Canada Department of Pathology Maisonneuve-Rosemont Hospital University of Montreal Montreal H3L 2H8 Canada

A 72 year-old female developed a herpetic esophagitis after 3 d of oral corticotherapy for an acute exacerbation of chronic obstructive pulmonary disease,presenting as odynophagia and total *** were taken during a first esophagogastroduodenoscopy(EGD) and the patient was referred to the thoracic surgery service with a presumptive diagnosis of esophageal cancer.A second EGD was planned for dilatation,but by that time the stenosis was completely *** biopsies taken during the first EGD revealed multiple herpetic viral inclusions and ulcerations without any dysplasia or *** front of a severe esophageal stenosis,one must still exclude the usual differential diagnosis peptic stenosis and *** of endoscopic lesions can suggest the diagnosis but must be promptly confirmed by biopsy,viral culture or polymerase chain *** immune systemic effects of corticotherapy are well known and herpetic esophagitis occurs most frequently in immunocompromised individuals,this case emphasizes the importance of clinical awareness concerning short courses of corticotherapy for immunocompetent *** article discusses the reactivation process of herpetic infection in this context and addresses its diagnostic and therapeutic issues.

关键词： Herpes simplex Esophagitis Dysphagia Corticosteroids Immunocompetence

Theranostic aspects of palladium‐based bimetallic nanoparticles in biomedical field:A state‐of‐the‐art

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Health Care Science

Health Care Science 2024年第3期3卷 181-202页

作者： Shwetha b.Nagarajan Sanjeevi Ramakrishnan Anuradha Jayaraman NIMS Institute of Allied Medical Science and Technology NIMS University RajasthanJaipurIndia

The exploration of newer antibacterial strategies is driven by antibiotic‐resistant microbes that cause serious public health *** recent years,nanoscale materials have developed as an alternative method to fight *** the fact that many nanomaterials have been discovered to be harmful,numerous researchers have shown a keen interest in nanoparticles(NPs)made of noble metals like silver,gold and *** make environmentally safe NPs from plants,green chemistry and nanotechnology have been combined to address the issue of *** study of bimetallic nanoparticles(bNPs)has increased tremendously in the past 10 *** production of bNPs mediated by natural extracts is straightforward,low cost and environmentally *** to their low toxicity,safety and biological stability,noble bNPs with silver,gold,platinum and palladium have the potential to be used in biomedical *** have a significant impact on human health and are used in medicine and pharmacy due to their biological characteristics,which include catalytic,antioxidant,antibacterial,antidiabetic,anticancer,hepatoprotective and regenerative activity.

关键词： antibiotic resistance bi‐metallic biocompatible nanomaterials palladium regenerative activity

Physical Land Suitability Assessment for the Large Cardamom Amomum subulatum *** in Hills of Kathmandu Valley

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Chinese Journal of Population,Resources and Environment 2009年第4期7卷 59-63页

作者： Nabarath baniya Michael behme Saroja baniya Centre for Research Innovation and Training(CRIT)KathmanduNepal Faculty of Agriculture and Horticulture Humboldt University of BerlinGermany Department of Plant Resources GoNThapathaliKathmanduNepal

Nepal is one of the top three exporters of larger cardamom （Amomum subulatum Roxb.） in the world market contributing largely to the Nepalese economy. Sub-Himalayan range of hilly area of eastern Nepal is popular for large cardamom cultivation. being similar phytogeographical and ecological setting, cultivation has begun in hills of Kathmandu Valley however land suitability needs to be evaluated with reference to specific need of the crop. Kathmandu is a valley with alluvial bottom and altitudinal range between 1200 and 2730m above sea level having cool to warm temperate climatic range. Varieties of aspects and slope gradient have potentiality for the large cardamom cultivation. Aim of the study was set to categorize available land area in the range of suitability for large cardamon cultivation on the basis of physical characteristics of the land and ecological need of crop. Land evaluation methodology has been designed along with site specific amendment in FAO framework （1976）. Land use map in scale of 1：25 000 was used in geographic information system environment. Suitability was done through map overlaying methods. Aim of the study was set to categorize available land area in the range of suitability categories for large cardamom cultivation based on physical characteristics of the land matching with ecological need of crop. Analysis of data shows that altitudinal range at uplands of Kathmandu Valley and annual average rainfall and temperature are found to be within suitability range for Amomum subulaturn cultivation. Sandy loam soil, slightly acidic in nature with gentle sloping land of about 5-8° provides highly suitable condition. Result showed that more than one-third of total land area above 1800 m of altitude is suitable. Selectively, of the total area, 5% are north facing slope, 13% gentle slopes are highly suitable. 16% lands with north east orientation are moderately suitable. Most of the land areas which are marginaly suitabile for vegetable and cereal c

关键词： land suitability GIS Amomum subulatum Roxb

Horseshoe thrombus in a patient with mechanical prosthetic mitral valve: A case report and review of literature

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World Journal of Clinical Cases 2015年第9期3卷 838-842页

作者： Sanjay Mehra Assad Movahed Carlos Espinoza Constantin b Marcu Department of Cardiovascular Sciences East Carolina University

Patients with prosthetic cardiac valves are at high risk for thromboembolic complications and need life long anticoagulation with warfarin, which can be associated with variable dose requirements and fluctuating level of systemic anticoagulation and may predispose to thromboembolic and or hemorrhagic complications. Prosthetic cardiac valve thrombosis is associated with high morbidity and mortality. A high index of suspicion is essential for prompt diagnosis. Transthoracic echocardiography, and if required transesophageal echocardiography are the main diagnostic imaging modalities. Medically stable patients can be managed with thrombolytic therapy and anticoagulation, while some patients may require surgical thrombectomy or valve replacement. We present a case report of a patient with prosthetic mitral valve and an unusually large left atrial thrombus with both thromboembolic and hemorrhagic complications.

关键词： Thrombosis Anticoagulation Thrombolytic therapy Transthoracic echocardiogram Prosthetic valves Transesophageal echocardiogram

THE EVOLuTION EQuATION OF JOINT PDF OF TuRbuLENT VELOCITY AND DISSIPATION

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Applied Mathematics and Mechanics(English Edition) 1989年第1期10卷 25-34页

作者：陈义良 S. b. Pope university of Science and Technology of China Hefeicornell University U. S. A.

According to the hypothesis that the dissipation of turbulent kinetic energy satisfies log-normal distribution, a stochastic model of dissipation is provided and the Langevin modef[6] of velocity is modified. Then a joint Pdf equation of turbulent velocity and dissipation is derived. We solve numerically the joint Pdf equation using Monte Carlo method and obtain satisfactory results for decaying turbulence and homogeneous turbulent shear flow. The preliminary results show that the model is well working.

关键词： THE EVOLuTION EQuATION OF JOINT PDF OF TuRbuLENT VELOCITY AND DISSIPATION