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Practice patterns among ophthalmic surgeons in treating concomitant oculoplastic conditions in preoperative period:A questionnaire-based study

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World Journal of Clinical Cases 2025年第1期13卷 29-37页

作者： bijnya birajita Panda Chitaranjan Mishra bhagabat nayak Avik Kumar Roy Logesh balakrishnan Priyadarshini Mishra Department of Ophthalmology All India Institute of Medical SciencesBhubaneswar 751019OdishaIndia Department of Vitreo-Retina Trilochan NetralayaSambalpur 768004India Department of Glaucoma Services LV Prasad Eye InstituteBhubaneswar 751013India Department of Statistics Apollo HospitalsChennai 823104India

bACKGROuND Addressing oculoplastic conditions in the preoperative period ensures both the safety and functional success of any ophthalmic *** oculoplastic conditions,like nasolacrimal duct obstruction,have been extensively studied,whereas others,like eyelid malposition and thyroid eye disease,have received minimal or no *** To investigate the current practice patterns among ophthalmologists while treating concomitant oculoplastic conditions before any subspecialty ophthalmic *** A cross-sectional survey was disseminated among ophthalmologists all over *** survey included questions related to pre-operative evaluation,anaesthetic and surgical techniques preferred,post-operative care,the use of adjunctive therapies,and patient follow-up *** A total of 180 ophthalmologists responded to the *** practitioners(89%)felt that the ROPLAS test was sufficient during pre-operative evaluation before any subspecialty surgery was *** most common surgical techniques employed were lacrimal drainage procedures(Dacryocystorhinostomy)(63.3%),eyelid malposition repair(36.9%),and ptosis repair(58.7%).Post-operatively,47.7%of respondents emphasized that at least a 4-week gap should be maintained after lacrimal drainage procedures and eyelid ***-seven percent of ophthalmologists felt that topical anaesthetic procedures should be preferred while performing ocular surgeries in thyroid eye disease *** Approximately 50%of ophthalmologists handle prevalent oculoplastic issues themselves,seeking the expertise of an oculoplastic surgeon under particular *** ophthalmologists still favor using ROPLAS as a preliminary screening method before proceeding with cataract *** conditions and thyroid eye disease are not as commonly addressed before subspecialty procedures compared to issues like nasolacrimal duct obstruction and periocular infections.

关键词： Oculoplasty Ophthalmic plastic surgery Nasolacrimal duct obstruction Practice patterns Survey

Diagnostic performance of C-reactive protein level and its role as a potential biomarker of severe dengue in adults

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Asian Pacific Journal of Tropical Medicine 2020年第8期13卷 358-365页

作者： Raghavendra Rao Snehal nayak Akhilesh K Pandey Shobha u Kamath Department of Medicine Kasturba Medical CollegeManipalIndia Manipal Academy of Higher Education ManipalIndia Department of biochemistry Kasturba Medical CollegeManipalIndia Department of Community Medicine Kasturba Medical CollegeManipalIndia

Objective: To determine the relationship between C-reactive protein(CRP) level and the severity of dengue and the potential use of CRP in predicting acute dengue ***: A prospective observational study was performed on dengue patients admitted to a tertiary care hospital in southern India. All patients of age above 18 years, diagnosed with dengue were included in the study. The detailed laboratory parameters pertaining to dengue were recorded. CRP levels were estimated and compared between groups i.e. severe and non-severe dengue. CRP cut-off value was detected using the receiver-operator ***: Totally 98 patients with a mean age of 40 years were included. Among them, 11.2% of the patients suffered from severe dengue, 54.1% of the cases had non-severe dengue without warning signs, and 34.7% had non-severe dengue with warning signs. The median CRP was significantly higher in patients with severe dengue compared to patients with non-severe dengue(96.2 mg/d L vs. 5.3 mg/d L). univariate logistic regression analysis showed that the odd’s ratio(OR) of CRP was 1.053(P≤0.001, 95% CI=1.029-1.078). CRP at a cutoff value of 21.6 mg/L(0.929 AuC) had excellent sensitivity(100%) and specificity(81.6%) in predicting severe dengue infection. Multivariate logistic regression analysis showed that CRP(OR=1.089, P=0.013) and ALT(OR=1.010, P=0.034) were statistically significant independent predictors of dengue ***: CRP level could be used as a potential biomarker to predict severity of dengue in adults.

关键词： Vector-borne Arbovirus Inflammation biochemical Tropical disease

Load dependent microstructural evolution in an as-cast 26%Cr high chromium cast iron during unlubricated sliding

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Friction 2022年第8期10卷 1258-1275页

作者： u.Pranav nayak Sebastian SuÁREZ Valentin PESNEL Frank MÜCKLICH María Agustina GuITAR Department of Materials Science Saarland UniversitySaarbrücken 66123Germany Materials Engineering Center Saarland Saarbrücken 66123Germany Ecole Européenne d’ingénieurs en Génie des Matériaux Universitéde LorraineNancy 54000France

In the current study,an as-cast 26%Cr high chromium cast iron(HCCI)alloy was subjected to dry-sliding linear wear tests,under different *** loads were selected based on analytically computing the critical load(PC)i.e.,the load necessary to induce plastic *** PC was calculated to be 15 N and accordingly,a sub-critical load(5 N)and an over-critical load(20 N)were *** influence of increasing the load during the wear test was investigated in terms of the matrix microstructural behaviour and its ability to support the surrounding *** morphological aspects of the wear tracks,and the deformed matrix microstructure adjacent and underneath the track was analysed by confocal laser scanning microscope(CLSM)and scanning electron microscope(SEM),*** evidence of plastic deformation of the matrix was observed below *** the contrary,at loads equal to and higher than PC,the austenitic matrix plastically deformed as evidenced by the presence of slip *** backscattered diffraction(EbSD)measurements in terms of grain reference orientation deviation,and micro-Vickers hardness of the austenitic matrix indicated a deformation depth of about 40μm at the maximum applied load of 20 *** active wear mechanisms during sliding were a combination of both adhesive and abrasive wear,although increasing the load shifted the dominant mechanism towards *** was primarily attributable to the increased propensity for carbide cracking and fracturing,combined with the inability of the hardened austenitic matrix surface and sub-surface to adequately support the broken carbide ***,the shift in the dominant wear mechanism was also reflected in the wear volume and subsequently,the wear rate.

关键词： high chromium cast iron unlubricated sliding plastic deformation wear resistance carbide spallation matrix hardness

Coastal zone management in India-present status and future needs

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Geo-Spatial Information Science 2017年第2期20卷 174-183页

作者： Shailesh nayak Earth System Science Organization New DelhiIndia

The coastal zone is a region where land,ocean and atmosphere interact and hence it is dynamic in *** has a long coastline which was not adequately monitored until the advent of the satellite remote sensing era in the *** has a very robust remote sensing program that the Indian Remote Sensing Satellite(IRS)series of satellites were effectively used to monitor coastal habitats,landforms,shoreline,water quality,etc.,and changes were identified during the last 40 *** classification system for coastal habitats and the classification and geometric accuracies of products were *** information for mangroves communities and characteristics of coral reefs were *** high and low tide lines were delineated seamlessly for the entire coastline using satellite *** these data were organized in a GIS and the coastal database for the entire country was *** of various hazards on such as cyclones,tsunami and sea level changes on coastal habitats were *** on topography,shoreline changes and tides,coastal multi-hazard vulnerability maps were characterized by employing the elevation data derived from satellite data and were prepared for the coastline of *** information on ocean color and sea surface temperature was used to generate potential fishery advisories,which are provided daily to *** coastal database was utilized effectively to identify coastal regulation zones,marine protected areas,vulnerable zones,*** services for tsunami,fishery and coral reef bleaching were generated for societal *** is planned to develop models for the coastal zone,so that impeding dangers and likely changes in the coastal zone can be predicted and suitable actions can be *** is necessary to integrate socio-economic data with the knowledge database of coastal zone to understand the impact of anthropogenic activities and the changing climate on the coastal zone.

关键词： Coastal zone india habitats processes water quality living resources coastal management

Molsidomine ameliorates diabetic peripheral neuropathy complications in Wistar rats

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Animal Models and Experimental Medicine 2021年第3期4卷 243-248页

作者： Pranav nayak b Minaz Nathani Khadar Pasha Pharmacology Department and Al-Ameen College of Pharmacy and Rajiv Gandhi university BangaloreIndia

Diabetic neuropathy is a disorder which affects various regions of the nervous sys-tem and there is no specific treatment available for ***,the present study eval-uated protective effect of molsidomine in diabetic neuropathy in *** was induced in male Wistar rats by administrating streptozotocin(52 mg/kg i.p).Diabetic rats were administered with molsidomine 5 mg/kg p.o,and 10mg/kg *** *** 8 weeks of treatment,Motor coordination,Mechanical allodynia,Mechanical hyperalgesia,Nerve conduction velocity,Glycosylated hemoglobin were *** animals were sacrificed and sciatic nerve was *** was used for reduced glutathione,lipid peroxidation and for *** with molsidomine significantly improved motor coordination,paw withdrawal threshold,mechanical threshold and nerve conduction ***,mol-sidomine treatment also reduced malondialdehyde levels and prevented depletion of reduced glutathione in sciatic nerve *** shows molsid-omine treatment maintained normal architecture of sciatic *** results of our study strengthens the alterative use of molsidomine in diabetic neuropathy.

关键词： diabetic neuropathy molsidomine streptozotocin Wistar rats

Effectiveness of state incentives for promoting wind energy： A panel data examination

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Frontiers in Energy 2015年第3期9卷 247-258页

作者： Deepak SANGROYA Jogendra nayak Department of Management Studies Indian Institute of Technology IIT Roorkee Roorkee 247667 India

Over the last decade, India has started to concentrate earnestly on renewable energy. The Indian government, as well as different state governments, are adopting policy instruments such as feed in tariff, captive consumption, renewable purchase obligation and genera- tion based incentive etc. aimed at renewable energy development. This paper evaluates the effectiveness of state level incentives for the development of wind energy in India. Fixed effect panel data modelling technique of econometric analysis is used to analyse the data of 26 Indian states in 11 years. The results show that feed in tariff and captive consumption are the significant predictors of wind energy development. However, renewable purchase obligation does not affect wind energy significantly.

关键词： India wind energy development state incen-tives econometric analysis panel data

Differential Power based Selective Phase Tripping for Fault-resilient Microgrid

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Journal of Modern Power Systems and Clean Energy 2022年第2期10卷 459-470页

作者： bhatraj Anudeep Paresh Kumar nayak the Department of Electrical Engineering Indian Institute of Technology(ISM)DhanbadDhanbadIndia

Modern fault-resilient microgrids(MGs)require the operation of healthy phases during unbalanced short-circuits to improve the system *** study proposes a differential power based selective phase tripping scheme for MGs consisting of synchronous and inverter-interfaced distributed generators(DGs).First,the differential power is computed using the line-end superimposed voltage and current ***,to make the scheme threshold-free,a power coefficient index is derived and used for identifying faulted phases in an *** protection scheme is tested on a standard MG operating in either grid-connected or islanding mode,which is simulated using PSCAD/*** efficacy of the scheme is also assessed on the OPAL-RT manufactured real-time digital simulation(RTDS)***,the performance of the proposed protection scheme is compared with a few existing *** results show that the selective tripping of faulted phases in MGs can be achieved quickly and securely using the proposed scheme.

关键词： Distributed generator differential power fault detection microgrid protection selective phase tripping.

Neuroinflammation revisited through the microglial lens

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Neural Regeneration Research 2025年第7期20卷 1989-1990页

作者： Renato Socodato João b.Relvas Institute of Research and Innovation in Health(i3S)and Institute for Molecular and Cell biology(IbMC) University of PortoPortoPortugal Department of biomedicine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivotal field,shedding light on the intricate dialogues between the central nervous system(CNS)and the immune *** exploration is particularly significant in understanding microglia,the CNS’s innate immune cells,beyond the conventional conflation of“neuroinflammation”and“microglial activation.”This conflation has clouded the true complexity of these processes,potentially stalling scientific progress and the development of new *** challenge the long-standing perspectives that have oversimplified these interactions,advocating for a deeper exploration of the dynamic relationship between neuroinflammation and microglial *** dissecting specific molecular pathways,we aim to illuminate their elaborate roles in neuroinflammatory responses,especially in the context of Alzheimer’s disease(AD).Here,neuroinflammation is not merely a passive observer or a direct antagonist but a complex agent in the disease’s *** article calls for a significant paradigm shift towards an integrative,multi-omics approach to *** such a comprehensive framework is crucial for advancing our understanding of neuroinflammatory conditions and paving the way for targeted therapeutic strategies for brain diseases.

关键词： inflammation simplified activation

Thermal Characteristics of Air-Water Spray Impingement Cooling of Hot Metallic Surface under Controlled Parametric Conditions

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Journal of Thermal Science 2016年第3期25卷 266-272页

作者： Santosh Kumar nayak Purna Chandra Mishra School of Mechanical Engineering KIIT University

Experimental results on the thermal characteristics of air-water spray impingement cooling of hot metallic surface are presented and discussed in this *** controlling input parameters investigated were the combined air and water pressures,plate thickness,water flow rate,nozzle height from the target surface and initial temperature of the hot *** effects of these input parameters on the important thermal characteristics such as heat transfer rate,heat transfer coefficient and wetting front movement were measured and *** flat plate samples of mild steel with dimension 120 mm in length,120 mm breadth and thickness of 4 mm,6 mm,and 8mm respectively were *** air assisted water spray was found to be an effective cooling media and method to achieve very high heat transfer rate from the *** heat transfer rate and heat transfer coefficients were obtained for the lesser i.e,4 mm thick *** in the nozzle height reduced the heat transfer efficiency of spray *** an inlet water pressure of 4 bar and air pressure of 3 bar,maximum cooling rates670℃/s and average cooling rate of 305.23℃/s were achieved for a temperature of 850℃ of the steel plate.

关键词： air-water spray transient temperature cooling rate plate thickness