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silicon nanowire formed via shallow anisotropic etching si-ash-trimming for specific DNA and electrochemical detection

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Chinese Physics B 2015年第6期24卷 607-612页

作者： Tijjani Adam u.HAshim Th s.Dhahi Institute of Nano Electronic Engineering(INEE) Universiti Malaysia Perlis(UniMAP) Physics Department College of Education for Pure ScienceBasra University

A functionalized silicon nanowire field-effect transistor （siNW FET） was fabricated to detect single molecules in the pM range to detect disease at the early stage with a sensitive, robust, and inexpensive method with the ability to provide specific and reliable data. The device was designed and fabricated by indented ash trimming via shallow anisotropic etching. The approach is a simple and low-cost technique that is compatible with the current commercial semiconductor standard CMOs process without an expensive deep reactive ion etcher. specific electric changes were observed for DNA sensing when the nanowire surface was modified with a complementary captured DNA probe and target DNA through an organic linker （--OCH2CH3） using organofunctional alkoxysilanes （3-aminopropyl） triethoxysilane （APTEs）. With this surface modification, a single specific target molecule can be detected. The simplicity of the sensing domain makes it feasible to miniaturize it for the development of a cancer detection kit, facilitating its use in both clinical and non-clinical environments to allow non-expert interpretation. With its novel electric response and potential for mass commercial fabrication, this biosensor can be developed to become a portable/point of care biosensor for both field and diagnostic applications.

关键词： silicon nanowire biosensor specific DNA detection anisotropic etching si-ash-trimming semi-conductor pH sensor

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Crystallization of Ternary Amorphous Ni-Y-AI Films Observed by scanning Tunneling Microscopy

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Chinese Physics Letters 1998年第12期15卷 901-903页

作者： WANG De-liang u.Geyer s.schneider National Laboratory for superconductivity Institute of PhysicsChinese Academy of SciencesBeijing 100080 Physikalisches Institut Universitaet Goettingen37073 GoettingenGermany

Ternary thin Ni90-xYxAl10 films have been prepared by using cocondensation method under ultrahigh vacuum *** with a wide concentration range between Ni80Y10Al10 and Ni20Y70AI10 were found to be *** an addition of 10at.%AI the thermal stability of binary amorphous NiY has been *** is caused by a more closely packed structure and the bondings between AI and Ni,Y may also play an important *** surface investigation by scanning tunneling microscopy suggests that the atom redistribution and the crystallization have been limited in the clusters with a size of about *** nanosized amorphous clusters of Ni80Y10Al10 film have changed to nanosized crystalline with the same size of about 12.3nm when crystallization occurred.

关键词： amorphous Ternary crystallization

Thermal Properties of Ni–Cr–si–B–Fe Based Interlayer Material and Its Application in TLP Bonding of IN 718 superalloy

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Acta Metallurgica sinica(English Letters) 2020年第12期33卷 1666-1680页

作者： u.K.Tarai P.s.Robi sukhomay Pal Department of Mechanical Engineering IIT GuwahatiGuwahati 781039India

A new Ni–Cr–si–B–Fe fi ller material is prepared for transient liquid-phase(TLP)bonding of Inconel 718 superalloy by mechanical alloying *** melting temperature range of the fi ller material and its activation energy of melting are determined by diff erential scanning calorimetry *** activation energy and melting temperature of the alloy powder decrease with increasing milling *** 718 alloy was joined via TLP by using the newly developed fi ller *** eff ect of TLP bonding temperature and time on microstructural evolution and mechanical properties of the joint was *** distinct microstructural regions were observed in the bonding area:isothermal solidifi cation zone consisting of a single-phase solid solution,diff usion aff ected zone consisting of extensive diff usion-induced precipitates of metallic boride,and unaff ected base *** ultimate shear strength and microhardness of the TLP-bonded joint increase with bonding time and temperature.

关键词： Transient liquid-phase(TLP)bonding Kissinger plot Mechanical alloying Inconel 718

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u.s. GEOLOGICAL suRVEY PROGRAMs AND INVEsTIGATIONs RELATED TO sOIL AND WATER CONsERVATION

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International Journal of sediment Research 2001年第3期16卷 421-429页

作者： W. R. OsTERKAMP and J. R. GRAY Research Hydrologist, u. s. Geological survey, 1675 W. Anklam Road, Tucson, AZ 85745 u. s. A. Hydrologist, u. s. Geological survey, 415 National Center, Reston, VA 20192 u. s. A. Research Hydrologist U. S. Geological Survey 1675 W. Anklam Road Tucson AZ 85745 U. S. A Hydrologist U. S. Geological Survey 415 National Center Reston VA 20192 U. S. A

The u.s. Geological survey has a rich tradition of collecting hydrologic data, especially for fluxes of water and suspended sediment, that provide a foundation for studies of soil and water conservation. Applied and basic research has included investigations of the effects of land use on rangelands, croplands, and forests; hazards mapping; derivation of flood and drought frequency, and other statistics related to streamflow and reservoir storage; development and application of models of rainfall-runoff relations, chemical quality, and sediment movement; and studies of the interactive processes of overland and channel flow with vegetation. Networks of streamgaging stations and (or) sampling sites within numerous drainage basins are yielding information that extends databases and enhances the ability to use those data for interpretive studies.

关键词： soil Water sediment Erosion Conservation u. s. Geological survey

Comparative Analysis of Machine Learning Models for Customer Churn Prediction in the u.s. Banking and Financial services: Economic Impact and Industry-specific Insights

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Journal of Data Analysis and Information Processing 2024年第3期12卷 388-418页

作者： Omoshola s. Owolabi Prince C. uche Nathaniel T. Adeniken Oghenekome Efijemue samuel Attakorah Oluwabukola G. Emi-Johnson Emmanuel Hinneh Department of Data science Carolina University Winston-Salem NC USA Department of Computer science Austin Peay State University Clarkesville TN USA Department of statistical sciences Wake Forest University Winston-Salem NC USA

Customer churn poses a significant challenge for the banking and finance industry in the united states, directly affecting profitability and market share. This study conducts a comprehensive comparative analysis of machine learning models for customer churn prediction, focusing on the u.s. context. The research evaluates the performance of logistic regression, random forest, and neural networks using industry-specific datasets, considering the economic impact and practical implications of the findings. The exploratory data analysis reveals unique patterns and trends in the u.s. banking and finance industry, such as the age distribution of customers and the prevalence of dormant accounts. The study incorporates macroeconomic factors to capture the potential influence of external conditions on customer churn behavior. The findings highlight the importance of leveraging advanced machine learning techniques and comprehensive customer data to develop effective churn prevention strategies in the u.s. context. By accurately predicting customer churn, financial institutions can proactively identify at-risk customers, implement targeted retention strategies, and optimize resource allocation. The study discusses the limitations and potential future improvements, serving as a roadmap for researchers and practitioners to further advance the field of customer churn prediction in the evolving landscape of the u.s. banking and finance industry.

关键词： Churn Prediction Machine Learning Economic Impact Industry-specific Insights Logistic Regression Random Forest Neural Networks

Mango Pest Detection using Entropy-ELM with Whale Optimization Algorithm

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Intelligent Automation & soft Computing 2023年第3期35卷 3447-3458页

作者： u.Muthaiah s.Chitra Department of Computer science and Engineering Sri Shanmugha College of Engineering and TechnologySankari637304India Department of Computer science and Engineering Er.Perumal Manimekalai College of EngineeringHosur635117India

Image processing,agricultural production,andﬁeld monitoring are essential studies in the researchﬁ*** diseases have an impact on agricultural production and *** disease detection at a preliminary phase reduces economic losses and improves the quality of *** identifying the agricultural pests is usually evident in plants;also,it takes more time and is an expensive technique.A drone system has been developed to gather photographs over enormous regions such as farm areas and *** atmosphere generates vast amounts of data as it is monitored closely;the evaluation of this big data would increase the production of agricultural *** paper aims to identify pests in mango trees such as hoppers,mealybugs,inﬂorescence midges,fruitﬂies,and stem *** of the massive volumes of large-scale high-dimensional big data collected,it is necessary to reduce the dimensionality of the input for classify-ing *** community-based cumulative algorithm was used to classify the pests in the existing *** proposed method uses the Entropy-ELM method with Whale Optimization to improve the classiﬁcation in detecting pests in *** Entropy-ELM method with the Whale Optimization Algorithm(WOA)is used for feature selection,enhancing mango pests’classiﬁcation *** Vector Machines(sVMs)are especially effective for classifying while users get var-ious classes in which they are *** are created as suitable classiﬁers to categorize any dataset in Big Data *** proposed Entropy-ELM-WOA is more capable compared to the existing systems.

关键词： Whale optimization algorithm Entropy-ELM feature selection pests detection support vector machine mango trees classiﬁcation

Interindividual Age-Independent Differences in Human CX43 Impact Ventricular Arrhythmic Risk

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Research 2024年第3期6卷 417-432页

作者： Laura García-Mendívil María Pérez-Zabalza Antoni Oliver-Gelabert JoséMaría Vallejo-Gil Javier Fañanás-Mastral Manuel Vázquez-sancho Javier AndréBellido-Morales Alexánder sebastián Vaca-Núñez Carlos Ballester-Cuenca Emiliano Diez Laura Ordovás Esther Pueyo Biomedical signal Interpretation and Computational simulation group(BsICos) Aragón Institute of Engineering ResearchUniversity of ZaragozaZaragoza 50018Spain BsICos Instituto de Investigación Sanitaria Aragón(IISA)Zaragoza 50018Spain Centro universitario de la Defensa(CuD) Zaragoza 50090Spain. Department of Cardiovascular surgery University Hospital Miguel ServetZaragoza 50009Spain. Institute of Experimental Medicine and Biology of Cuyo(IMBECu) CONICETMendoza 5500Argentina. Fundación Agencia Aragonesa para la Investigación y el Desarrollo(ARAID) Zaragoza 50018Spain. Biomedical Research Networking Center in Bioengineering Biomaterials and Nanomedicine(CIBER-BBN)Zaragoza 50018Spain.

Connexin 43 (CX43) is one of the major components of gap junctions, the structures responsible for the intercellular communication and transmission of the electrical impulse in the left ventricle. There is limited information on the histological changes of CX43 with age and their effect on electrophysiology, especially in humans. Here, we analyzed left ventricular biopsies from living donors starting at midlife to characterize age-related CX43 remodeling. We assessed its quantity, degree of lateralization, and spatial heterogeneity together with fibrotic deposition. We observed no significant age-related remodeling of CX43. Only spatial heterogeneity increased slightly with age, and this increase was better explained by biological age than by chronological age. Importantly, we found that CX43 features varied considerably among individuals in our population with no relevant relationship to age or fibrosis content, in contrast to animal species. We used our experimental results to feed computational models of human ventricular electrophysiology and to assess the effects of interindividual differences in specific features of CX43 and fibrosis on conduction velocity, action potential duration, and arrhythmogenicity. We found that larger amounts of fibrosis were associated with the highest arrhythmic risk, with this risk being increased when fibrosis deposition was combined with a reduction in CX43 amount and/or with an increase in CX43 spatial heterogeneity. These mechanisms underlying high arrhythmic risk in some individuals were not associated with age in our study population. In conclusion, our data rule out CX43 remodeling as an age-related arrhythmic substrate in the population beyond midlife, but highlight its potential as a proarrhythmic factor at the individual level, especially when combined with increased fibrosis.

关键词： CX43 rhythm Independent

Experimental study of corner separation and unsteady characteristics in linear compressor cascades with and without sweeping jet actuator

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Propulsion and Power Research 2024年第3期13卷 360-374页

作者： s.W.Chen W.H.Li C.Xu Q.H.Meng school of Energy science and Engineering Harbin Institute of TechnologyHarbinHeilongjiang 150001China AVIC shenyang Aircraft Design and Research Institute Shenyang 110035China

sweeping jet actuator(sJA)has been widely applied for activeflow control in *** this paper,the sJA character in compressor cascade and its performance for separation control in innerflows are ***-averaged and transientflowfield measurement,together with visualization methods are *** is found that endwall effects are important for both sJA behaviors and sJA performance for separation control in compressor *** is a maximum of 12.7%total pressure loss reduction with sJA placed near the separation position,close to the endwall and under *** characteristic frequencies in theflowfield contribute to the capture of influence regions of vortices and excitation *** concentrated shedding vortices and sJA jets impact region helped to judge that sJA energizes low momentumfluids in a large region and matches the high loss core *** be concrete,theflow separation control mechanism of sJA lies on the interruption of the blade suction surface boundary layer development and the restriction of the lifting of the boundary layer from end-wall towards blade suction surface.

关键词： Compressor cascade Activeflow control sweeping jet actuator Corner separation Oilflow visualization

sources and Deficiency Diseases of Mineral Nutrients in Human Health and Nutrition:A Review

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Pedosphere 2014年第1期24卷 13-38页

作者： u.C.GuPTA s.C.GuPTA Agriculture and Agri-Canada Canada Crops and Livestock Research Centre The Department of Plastic surgery Loma Linda University

Mineral nutrients are fundamentally metals and other inorganic compounds. The life cycle of these mineral nutrients begins in soil, their primary source. soil provides minerals to plants and through the plants the minerals go to animals and humans; animal products are also the source of mineral nutrients for humans. Plant foods contain almost all of the mineral nutrients established as essential for human nutrition. They provide much of our skeletal structure, e.g., bones and teeth. They are critical to countless body processes by serving as essential co-factors for a number of enzymes. Humans can not utilize most foods without critical minerals and enzymes responsible for digestion and absorption. Though mineral nutrients are essential nutrients, the body requires them in small, precise amounts. We require them in the form found in crops and they can be classified into three different categories： major, secondary, and micro or trace minerals. This classification is based upon their requirement rather than on their relative importance. Major minerals such as potassium （K） and phosphorus （P） are required in amounts of up to 10 g d-1. The daily requirement of secondary and micro minerals ranges from 400 to 1 500 mg d-1 and 45 ~tg d-1 to 11 mg d-1, respectively. To protect humans from mineral nutrient deficiencies, the key is to consume a variety of foods in modest quantities, such as different whole grains, low fat dairy, and different meats, vegetables and fruits. For insurance purposes, a supplement containing various mineral nutrients can be taken daily.

关键词： deficiency diseases deficiency symptoms origin recommended daily dose toxicity

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