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中华器官移植杂志 2024年第2期45卷 104-109页

作者：张浩涵马铭吴佳沛范钰林涛宋涂润四川大学华西医院泌尿外科泌尿外科研究所器官移植中心成都610047

目的探索经阴道机器人辅助肾移植(robotic-assisted kidney transplantation,RAKT)的可行性及安全性。方法回顾性分析2021年6月28日四川大学华西医院1例经阴道RAKT手术的病例资料。通过持续肾表面冷却技术(continuous surface cooling t... 详细信息

目的探索经阴道机器人辅助肾移植(robotic-assisted kidney transplantation,RAKT)的可行性及安全性。方法回顾性分析2021年6月28日四川大学华西医院1例经阴道RAKT手术的病例资料。通过持续肾表面冷却技术(continuous surface cooling technique,CSCT)术中使用冰生理盐水对移植肾进行冷却,使用达芬奇机器人辅助经会阴入路切开阴道后穹窿,置入移植物。术后对受者进行了3个月的随访。此外,以"机器人肾移植"和"阴道"为中文检索关键词,以"kidney transplantation"、"robot"和"vaginal"为英文检索关键词在万方数据库、中国知网、维普数据库、中国生物医学文献服务系统、PubMed、Embase和CENTRAL数据库检索发表时间为1990年6月至2022年6月的文献,详细总结已发表的所有病例。结果手术经过顺利完成,总时长为250 min,血管吻合时间为45 min,温缺血时间为63 min。受者术后恢复顺利,无阴道疼痛,无需术后镇痛;未发现腹腔感染。吻合时移植物表面温度维持于10~16℃。经文献检索,目前一共报道了12例经阴道的RAKT;除1例移植物位置不佳中转开放手术之外,所有病例均获得成功。文献报道的平均手术时间为(210±37)min,血管吻合时间为(41±8)min,温缺血时间为(50±10)min,无外科并发症发生。结论经阴道RAKT手术是安全可行的,应严格把握适应证并在术前做好评估。

关键词：肾移植微创手术机器人辅助技术自然腔道手术

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维普期刊数据库

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机器人辅助腹腔镜肾脏移植术专家共识

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微创泌尿外科杂志 2024年第2期13卷 73-78页

作者：范阳蔡明付迎欣金海龙江军林涛宋涂润孙洵王瀚锋周晓峰张旭董隽中国人民解放军总医院第三医学中心泌尿外科北京100039 浙江大学医学院附属第二医院泌尿外科杭州310003 深圳市第三人民医院泌尿外科深圳518112 中国人民解放军总医院第三医学中心器官移植科北京100039 陆军军医大学特色医学中心泌尿外科重庆400042 四川大学华西医院泌尿外科成都610041 昆明市第一人民医院泌尿外科昆明650034 中日友好医院泌尿外科北京100029

机器人辅助腹腔镜肾脏移植是器官移植领域微创手术的代表,国内外多个移植中心经验已证明其可行和安全。但在临床实践中,该术式适应证、禁忌证、手术方法、安全注意事项、并发症处理及手术疗效等关键问题亟需形成专家共识。为了进一步规... 详细信息

机器人辅助腹腔镜肾脏移植是器官移植领域微创手术的代表,国内外多个移植中心经验已证明其可行和安全。但在临床实践中,该术式适应证、禁忌证、手术方法、安全注意事项、并发症处理及手术疗效等关键问题亟需形成专家共识。为了进一步规范和推广该项技术,该领域专家聚焦上述问题检索了相关证据,并通过会议讨论、德尔菲问卷调查等方法达成共识,供广大临床医师参考。

关键词：肾脏移植机器人外科手术腹腔镜微创手术共识

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维普期刊数据库

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Transplant outcomes of 100 cases of living-donor ABO-incompatible kidney transplantation

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Chinese Medical Journal 2022年第19期135卷 2303-2310页

作者： Saifu Yin Qiling Tan Youmin Yang Fan Zhang turun song Yu Fan Zhongli Huang Tao Lin Xianding Wang Department of Urology Institute of UrologyOrgan Transplantation CenterWest China HospitalSichuan UniversityChengduSichuan 610041China The Third Comprehensive Care Unit West China HospitalWest China School of NursingSichuan UniversityChengduSichuan 610041China.

Background:Although ABO-incompatible(ABOi)kidney transplantation(KT)has been performed successfully,a standard preconditioning regimen has not been *** on the initial antidonor ABO antibody titers,an individualized preconditioning regimen is developed,and this study explored the efficacy and safety of the ***:From September 1,2014,to September 1,2020,we performed 1668 consecutive living-donor KTs,including 100 ABOi and 1568 ABO-compatible(ABOc)*** KT recipients(KTRs)with a lower antibody titer(≤1:8)were administered oral immunosuppressive drugs(OIs)before KT,while patients with a medium titer(1:16)received OIs plus antibody-removal therapy(plasma exchange/double-filtration plasmapheresis),patients with a higher titer(≥1:32)were in addition received rituximab(Rit).Competing risk analyses were conducted to estimate the cumulative incidence of infection,acute rejection(AR),graft loss,and patient ***:After propensity score analyses,100 ABOi KTRs and 200 matched ABOc KTRs were *** were no significant differences in graft and patient survival between the ABOi and ABOc groups(P=0.787,P=0.386,respectively).After using the individualized preconditioning regimen,ABOi KTRs showed a similar cumulative incidence of AR(10.0%vs.10.5%,P=0.346).Among the ABOi KTRs,the Rit-free group had a similar cumulative incidence of AR(P=0.714)compared to that of the Rittreated *** competing risk analyses revealed that a Rit-free regimen reduced the risk of infection(HR:0.31;95%CI:0.12–0.78,P=0.013).Notably,antibody titer rebound was more common in ABOi KTRs receiving a Rit-free preconditioning regimen(P=0.013)than those receiving *** KTRs with antibody titer rebound had a 2.72-fold risk of AR(HR:2.72,95%CI:1.01–7.31,P=0.048).ABOi KTRs had similar serum creatinine and estimated glomerular filtration rate compared to those of ABOc KTRs after the first ***:An individualized preconditioning regimen can achieve comp

关键词： ABO blood-group system Kidney transplantation Rituximab Immunologic desensitization

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维普期刊数据库

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The impact of posttransplant anemia duration on the long term outcome in living related kidney transplantation

The impact of posttransplant anemia duration on the long ter...

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2013中国器官移植大会

作者： Tao Lin turun song Li Wang Shaofeng He Lei Fu Zhongli Huang Qiang Wei Department of Urology West China HospitalSichuan University

Backgroud Post-transplant anemia(PTA) is believed a negative factor for long term outcome in kidney ***, the impact of PTA duration on kidney transplantation is far from being well addressed. Methods A retrospective study was conducted by reviewing the medical profile of the patients who received living related kidney transplantations at our center from January 2006 and June 2012..Anemia was defined by a Chinese criteria,as Hb <120g/L for men and Hb<110g/L for *** on the Hb level at 1,3,6 and 12 month,patients were divided into five groups:Goup I(PTA duration≤1 month),Group II(1 month< PTA duration≤3 months),Group III(3 months< PTA duration≤6 months),Group IV(6 months< PTA

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Change in remaining Renal Parenchymal Volume in living kidney donors after kidney donation

Change in remaining Renal Parenchymal Volume in living kidne...

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2013中国器官移植大会

作者： Tao Lin turun song Li Wang Shaofeng He Lei Fu Zhongli Huang Qiang Wei department of Urology West China HospitalSichuan University

Purpose Uninephrectomy would induce compensatory hypertrophy and function in the remaining *** investigated the relationship between changes in renal parenchymal volume(RPV) and renal function after nephrectomy in living kidney donors. Materials and Methods From July 2011 and January 2012,45 living kidney donors were enrolled in this *** resonance scanning was performed before surgery,3 days and 7 days after surgery,and RPV was calculated through disc summerize *** were followed up for one year. Results The RPV of the remaining kidney was 118.06±23.51cm3 and then increased by 21.23%to 143.13±25.52 cm3 at 3 days, and by 24.17%to 146.60±25.86 cm at 7 *** regression analysis showed that preoperative RPV of the remaining kidney was positively associated with glomerular filtration rate(GFR) of remaining kidney(P= 0.037) and RPV of resected kidney(P<0.001),

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The pre-transplant anemic condition is independent of long term outcome in living related kidney transplantation

The pre-transplant anemic condition is independent of long t...

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2013中国器官移植大会

作者： Tao Lin turun song Li Wang Shaofeng He Lei Fu Zhongli Huang Qiang Wei Department of Urology West China HospitalSichuan University

Backgroud The relationship between pre-transplant Hemoglobin(Hb) concentration and long term outcome in living related kidney transplantation is far from well addressed. Materials and Methods A retrospective cohort st...

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Assessment of intra-renal oxygenation in transplanted kidney with BOLD-MRI:the preliminary results

Assessment of intra-renal oxygenation in transplanted kidney...

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2012中国器官移植大会

作者： Tao lin 1,turun song 1,shaofeng he 1,lei fu 1,zixing huang 1 四川大学华西医院泌尿外科四川大学华西医院放射科

【Objectives】BOLD(blood oxygen level dependent) MR imaging is now being experimental utilized to determine the intra-tissue oxygenation,with higher R2 value indicating poorer *** study is to prospectively assess the change of oxygenation status in transplanted kidney before and after kidney transplantation.【Materials】This study had institutional human subjects review committee approval,and written informed consent was obtained from all *** MR imaging was performed in 36 pairs of living donors and recipients within 5 days prior to

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Assessment of intra-renal oxygenation in renal donor with BOLD-MRI

Assessment of intra-renal oxygenation in renal donor with BO...

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2013中国器官移植大会

作者： Tao Lin turun song Li Wang Shaofeng He Lei Fu Zhongli Huang Dongyang Zeng Qiang Wei Department of Urology West China HospitalSichuan University

Objective To examine change of the apparent relaxation rate R2* values in living kidney donors after uninephrectomy by Blood oxygenation level dependent(BOLD)magnetic resonance imaging(MRI). Materials and Methods From July 2011 to January 2012,45 living kidney donors were enrolled in this *** MRI scanning was performed before surgery,3 days and 7 days after *** were followed up for one year. Results The R2* values in medulla(mR2*)were significantly greater than that of cortex(cR2*),both in resected kidney and remaining ***2* values of the remaining kidney was 17.52±1.36 s,and then decrease significantly by 8.97%to 15.95±1.14 sat

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Diffusion-weighted MR Imaging of Native and Transplanted Kidneys:the preliminary results

Diffusion-weighted MR Imaging of Native and Transplanted Kid...

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2012中国器官移植大会

作者： tao lin 1,turun song 1,shaofeng he 1,lei fu1,zixing huang 1 四川大学华西医院泌尿外科四川大学华西医院放射科

【Objectives】Diffusion-weighted MR Imaging(DWI) is now is quantified by the apparent diffusion coefficient(ADC) (×10^3 mm 2/sec),which provides information on diffusion,with higher ADC value indicating better water molecule diffusion. This study is to prospectively assess the change of diffusion status in transplanted kidney before and after kidney transplantation.【Materials】This study had institutional human subjects review committee approval,and written informed consent was

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Hypothermic machine perfusion versus static cold storage of kidney allografts from deceased donors:a systematic review and meta-analysis

Hypothermic machine perfusion versus static cold storage of ...

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2013中国器官移植大会

作者： Tao Lin turun song Li Wang Shaofeng He Lei Fu Zhongli Huang Qiang Wei Department of Urology West China HospitalSichuan University

Background Static cold storage is generally used to preserve kidney allografts from deceased *** machine perfusion may improve outcomes after transplantation but there have been few studies with limited power that have addressed this issue. The objective was to review systematically the evidence comparing outcomes from these two modalities. Materials and mGthodS We undertook a systematic search of the Medline,Embase databases and the Cochrane Central Register of Controlled *** were included in the *** outcomes were the incidence of delayed graft function(DGF), primary nonfunction(PNF);secondary outcomes were graft loss,and patient death at 1 year. Results A total of 12 studies were included for quantitative analysis,involving 1897 *** found that hypothermic machine

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