检索结果-南通市图书馆

Advancing early warning and surveillance for zoonotic diseases under climate change:Interdisciplinary systematic perspectives

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Climate Change Research 2023年第6期14卷 814-826页

作者： Chen-Xi WANG Le-Shan XIU Qin-Qin HU tung-chun lee Jia LIU Leilei SHI Xiao-Nong ZHOU Xiao-Kui GUO Liyuan HOU Kun YIN School of Global Health Chinese Center for Tropical Diseases ResearchShanghai Jiao Tong University School of MedicineShanghai 200025China One Health Center Shanghai Jiao Tong University-The University of EdinburghShanghai 200025China Institute for Materials Discovery University College London(UCL)BloomsburyLondon WCIE 7JEUnited Kingdom Deparment of Chemistry University College London(UCL)London WCIH OAJ.United Kingdm School of Arts and Sciences Carolina UniversityWinston-Salem NC2710lUSA Civil and Environmental Engineering Department Utah State UniversityLogan UT 84322USA Utah Water Research Laboratory Logan UT 84321USA

Zoonoses account for the majority of emerging infectious diseases and pose a serious threat to human and animal *** global warming and climate change,zoonoses are significantly affected by influencing hosts,vectors,and pathogen dynamics as well as their *** zoonoses surveillance relies on molecular or serological diagnostic methods to monitor pathogens from animal or patient samples,which may miss the early warning signs of pathogens spillover from the ***,new technologies such as remote sensing,environment-based screening,multi-omics,and big data science facilitate comprehensive active surveillance,offering great potential for early warning and *** the recent technological advances,there is few reviews that explores the integration of cutting-edge technologies aimed at constructing a robust early warning ***,we discussed the opportunities,barriers,and limitations of interdisciplinary emerging technologies for exploring early warning and surveillance of *** systematic review summarized a practical framework for early surveillance integrated with a modified SEIR model for zoonoses in the context of climate *** also outlined challenges and future prospects in terms of data sharing,early detection of unknown zoonoses and the move towards global surveillance.

关键词： Zoonoses Surveillance system Early warning Climate change Interdisciplinary

Anion-hosting cathodes for current and late-stage dual-ion batteries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第5期67卷 1485-1509页

作者： Miao Zhang Wenyong Zhang Fan Zhang chun-Sing lee Yongbing Tang School of Chemistry and Materials Science Guangdong University of EducationGuangzhou 510303China Advanced Energy Storage Technology Research Center Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Center of Super-Diamond and Advanced Film(COSDAF) City University of Hong KongKowloon 999077China

Anion-hosting cathodes capable of reversibly storing large-size anions play a leading role in dual-ion batteries(DIBs). The purpose of the present review is to summarize the most promising anion-hosting cathodes for current and late-stage DIBs. This review first summarizes the developments in conventional graphite cathodes, especially the latest advances in the graphiterelated research. Next, organic cathodes for the anion storage are discussed, including aromatic amine polymers, heterocyclic polymers, bipolar compounds, and all-carbon-unsaturated compounds. Then, the review focuses on the conversion-type cathodes with high theoretical specific capacities. Finally, the future research directions of the cathodes of DIBs are proposed.

关键词： dual-ion batteries organic cathodes graphite cathodes conversion-type cathodes

Synthesis of crystalline g-C_(3)N_(4) with rock/molten salts for efficient photocatalysis and piezocatalysis

在线全文

学校读者我要写书评

暂无评论

Green Energy & Environment 2024年第5期9卷 890-898页

作者： Tingting Xu Jung Hur Ping Niu Shulan Wang Sangwook lee Sang-Eun chun Li Li Department of Chemistry College of ScienceNortheastern UniversityShenyang110819China State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang110819China School of Metallurgy Northeastern UniversityShenyang110819China School of Materials Science and Engineering Kyungpook National UniversityDaegu41566Republic of Korea School of Industrial Technology Advances Kyungpook National UniversityDaegu41566Republic of Korea

Graphitic carbon nitride(g-C_(3)N_(4))is emerging as a promising visible-light photocatalyst while the low crystallinity with sluggish charge separation/migration dynamics signiﬁcantly restricts its practical ***,synthesizing highly crystalline g-C_(3)N_(4) with sufﬁcient surface activities still remains ***,different from using alkali molten salts which is commonly reported,we propose an approach for synthesis of highly crystalline g-C_(3)N_(4) with FeCl3/KCl rock/molten mixed *** rock salt can serve as the structure-directing template while molten salt provides the required liquid medium for ***,the synthesized photocatalyst showed further enhanced crystallinity and improved surface area along with high p/p*excitation compared with crystalline C_(3)N_(4) prepared from conventional molten-salt *** catalytically advantageous features lead to its superior photocatalytic and piezocatalytic activities with a high reactivity for overall water splitting that is not commonly reported for C_(3)N_(4).This work provides an effective strategy for structural optimization of organic semiconductor based materials and may inspire new ideas for the design of advanced photocatalysts.

关键词： High crystallinity Carbon nitride Photocatalysis Piezocatalysis Overall water splitting

Community perspectives on the effectiveness of watershed management institutions in the Himalayas

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2024年第4期21卷 1119-1139页

作者： Nisha SILWAL Nabin DHUNGANA Rajan SUBEDI Suraj UPADHAYA chun-Hung lee Natural Resources Conservation Nepal(NRCN) ChitwanP.O.Box 44200Nepal Department of Natural Resources and Environmental Studies College of Environmental StudiesNational Dong Hwa UniversityHualien 97401Chinese Taipei Institute of Forestry Tribhuvan UniversityPokharaP.O.Box 43Nepal School of Agriculture and Natural Resources Kentucky State UniversityFrankfortKY 40601USA Himalayan Conservation and Research Institute DolpaP.O.Box 21400Nepal

The sustainability of environmental management initiatives,such as watershed management programs,relies on the presence of effective institutions at the watershed ***,there needs to be more empirical evidence from evaluating the effectiveness of watershed-level ***,this study presents a pioneering effort to evaluate the effectiveness of Nepal’s first watershed conservation committee at the watershed scale,focusing on the case of the Khageri Khola watershed in Central *** study involved conducting a household survey,key informant interviews,focus group discussions,and field observations to collect and analyze the *** analysis,index value calculation,and chi-square statistics were then employed to summarize the results regarding local respondents’perceptions of twelve institutional characteristics,their rationalities,and their association with socio-demographic *** results reveal that the watershed conservation committee was perceived as performing well in managing the ***,good interaction,appropriate scale,technical,environmental,social,organizational,and government rationality were perceived as highly effective,with an average index value of less than *** contrast,clarity of objectives and economic rationality showed moderate effectiveness,with an average index value ranging from 0.36 to ***,the results suggested that adaptiveness,compliance capacity,and financial rationality merit increased attention,intending to improve their ***,the results showed the association of socio-demographics with respondents’perceptions of various indicators of institutional characteristics and their ***,the study provides valuable insights for policymakers,researchers,and development practitioners charged with designing sustainable and effective programs and *** enhance the effectiveness and sustainability of watershed management programs,we recommen

关键词： Watershed Watershed institutions Indicators Institutional characteristics Rationalities Nepal.

Origami multi-layer space shield for cylindrical space structure

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2024年第10期37卷 294-312页

作者： Ji-Hun CHA Ji-Sub NOH Sarath Kumar SATHISH KUMAR Dohyeon JIN Dae-Young lee chun-Gon KIM Department of Aerospace Engineering Chosun UniversityGwangju 61452Republic of Korea Department of Aerospace and Software Engineering Gyeongsang National UniversityGyeongsangnam-do 52828Republic of Korea Department of Aerospace Engineering Seoul National UniversitySeoul 08826Republic of Korea Department of Aerospace Engineering KAISTDaejeon 34141Republic of Korea

The multidisciplinary space environment,encompassing orbital debris,cosmic radiation,and solar radiative heat,poses significant risks to spacecraft and astronauts,necessitating efficient and effective shielding solutions.A multi-layer shield with wide spacing has been proven to be an effective way to shield the spacecraft from space debris impact;however,due to the limited volume of the payload fairing,it was not feasible to apply a multi-layer shield to the spacecraft *** the origami design,the shield maintains a compact form during launch and subsequently expands in outer space to enhance *** geometric analysis,it has been confirmed that the deployable multi-layer space shield can occupy less space than conventional space shield structures while expanding into wider shield intervals and multiple *** hypervelocity impact experiments,it was confirmed that as the bumper spacing of the multi-layer space shield expands,its ballistic performance becomes superior to conventional space *** deployable multi-layer space shield can reduce not only hypervelocity impacts but also solar radiative heat using the same mechanism as multi-layer *** cosmic radiation dose analysis,it has been confirmed that the multi-layer space shield is effective in cosmic radiation shielding compared to conventional space structures.

关键词： Hybrid composite Origami Hypervelocity impact Space environment Space debris Cosmic radiation

A Stable Open-Shell Conjugated Diradical Polymer with Ultra-High Photothermal Conversion Efficiency for NIR-Ⅱ Photo-Immunotherapy of Metastatic Tumor

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2024年第2期16卷 1-14页

作者： Yijian Gao Ying Liu Xiliang Li Hui Wang Yuliang Yang Yu Luo Yingpeng Wan chun‑sing lee Shengliang Li Xiao‑Hong Zhang College of Pharmaceutical Sciences Soochow UniversitySuzhou 215123People’s Republic of China Institute of Functional Nano&Soft Materials(FUNSOM) Soochow UniversitySuzhou 215123People’s Republic of China Center of Super‑Diamond and Advanced Films(COSDAF)&Department of Chemistry City University of Hong Kong83 Tat Chee AvenueKowloonHong Kong SARPeople’s Republic of China

Massive efforts have been concentrated on the advance of eminent near-infrared(NIR) photothermal materials(PTMs) in the NIR-Ⅱ window(1000–1700 nm), especially organic PTMs because of their intrinsic biological safety compared with inorganic PTMs. However, so far, only a few NIR-Ⅱresponsive organic PTMs was explored, and their photothermal conversion efficiencies(PCEs) still remain relatively low. Herein, donor–acceptor conjugated diradical polymers with open-shell characteristics are explored for synergistically photothermal immunotherapy of metastatic tumors in the NIR-Ⅱ window. By employing side-chain regulation, the conjugated diradical polymer TTB-2 with obvious NIR-Ⅱ absorption was developed, and its nanoparticles realize a record-breaking PCE of 87.7% upon NIR-Ⅱ light illustration. In vitro and in vivo experiments demonstrate that TTB-2 nanoparticles show good tumor photoablation with navigation of photoacoustic imaging in the NIR-Ⅱ window, without any side-effect. Moreover, by combining with PD-1 antibody,the pulmonary metastasis of breast cancer is high-effectively prevented by the efficient photo-immunity effect. Thus, this study explores superior PTMs for cancer metastasis theranostics in the NIR-Ⅱ window, offering a new horizon in developing radical-characteristic NIR-Ⅱ photothermal materials.

关键词： NIR-Ⅱconjugated polymer Photothermal Radical Nanoparticles Cancer therapy

Acceptor-planarized typeⅠphotosensitizer for lipid droplet-targeted two-photon photodynamic therapy by ferroptosis

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2024年第7期67卷 2392-2402页

作者： Jie Sha Weimin Liu Jiasheng Wu Yanping Wang Xuewei Li Haohui Ren Zhi Pang Wenjun Zhang chun-Sing lee Pengfei Wang Key Laboratory of Photochemical Conversion and Optoelectronic Materials CityU-CAS Joint Laboratory of Functional Materials and DevicesTechnical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China School of Future Technology University of Chinese Academy of SciencesBeijing 100049China Center of Super-Diamond and Advanced Films&Department of Materials Science and Engineering City University of Hong KongHong KongChina

Two-photon photodynamic therapy(TP-PDT)has garnered significant attention because of its excellent depth of tissue penetration and high spatiotemporal ***,the limited targeting ability and oxygen dependency of photosensitizers(PSs)significantly hinder the effectiveness of photodynamic therapy in hypoxic tumor ***,we designed and synthesized two lipid droplet(LD)-targeted two-photon PSs(TBPCP and TBCP)by reducing benzene rings to achieve“acceptor planarization”.Notably,acceptor planarization not only enhanced the intramolecular charge transfer but also transferred the photochemical reaction from typeⅡ(TBPCP)to typeⅠ(TBCP).Under the irradiation of 940 nm femtosecond pulsed laser,TBPCP and TBCP showed bright two-photon-excited fluorescence and excellent LD targeting in living *** TBPCP(typeⅡPS),the outstanding TP-PDT efficacy of TBCP(typeⅠPS)under hypoxic conditions could be obtained in both cellular experiments and multicellular tumor spheroids(MCTS)***,both TBPCP and TBCP could induce the lipid peroxidation in the typeⅠor typeⅡPDT due to the location of LD,depleting GSH and inactivating GPX4 to induce nonprogrammed ferroptosis in cells.

关键词： two-photon photodynamic therapy lipid droplet targeting acceptor planarization hypoxia tumor ferroptosis

SUV39H1-driven NFATc1 methylation is essential for the c-Cbl-mediated degradation of NFATc1 in an osteoclast lineage

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第4期11卷 86-89页

作者： Do-Won Jeong Hye-Jin Kim Jong-Wan Park Seulbee lee Hyeryeon Jung Eugene C.Yi Nacksung Kime Yang-Sook chun Department of Biomedical Sciences Seoul National University College of MedicineSeoul 03080Republic of Korea Department of Physiology Seoul National University College of MedicineSeoul 03080Republic of Korea Ischemic/Hypoxic Disease Institute Seoul National University College of MedicineSeoul 03080Republic of Korea Department of Molecular Medicine and Biopharmaceutical Sciences Graduate School of Convergence Science and Technology and College of Medicine Or College of PharmacySeoul National UniversitySeoul 03080Republic of Korea Department of Pharmacology Chonnam National University Medical SchoolGwangju 61469Republic of Korea

Bone undergoes continuous remodeling by tightly-coordinated actions of bone-resorbing osteoclasts and boneforming osteoblasts.1 Recent studies document that the dysregulation of histone methylation profiles is associated with the progression of ***,the specific epigenetic modifiers are incompletely *** this study,we demonstrate an inhibitory role of a variegation 3-9 homolog 1(SUV39H1)in osteoclast formation.

关键词： osteoclast remodeling incomplete

Molecular Conformational Isomerization:An Efficient Way to Design Novel Emitters with Dual-Thermally Activated Delayed Fluorescence Characteristics and Their Optoelectronic and Bioimaging Applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CCS Chemistry 2024年第4期6卷 912-922页

作者： Yi-Zhong Shi Ya-Fang Xiao Hao Wu Shao-Li Zhang Xiao-chun Fan Ye Tian Chang-Qing Ye Kai Wang Jia Yu chun-Sing lee Xiao-Hong Zhang School of Materials Science and Engineering Suzhou University of Science and TechnologySuzhou 215009 Institute of Functional Nano and Soft Materials(FUNSOM) Joint International Research Laboratory of Carbon-Based Functional Materials and DevicesSoochow UniversitySuzhou 215123Jiangsu Center of Super-Diamond and Advanced Films(COSDAF) Department of ChemistryCity University of Hong KongHong Kong SAR School of Biomedical Engineering The Second Affiliated HospitalGuangzhou Medical UniversityGuangzhou 510260 Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices Soochow UniversitySuzhou 215123Jiangsu Jiangsu Key Laboratory of Advanced Negative Carbon Technologies Soochow UniversitySuzhou 215123Jiangsu

Single-molecule luminophores with dual-thermally activated delayed fluorescence(TADF)properties are receiving increasing ***,how to achieve these goals requires more in-depth ***,we demonstrate a novel example emitter,10-(5-(2-(pyridin-3-yl)-[4,5′-bipyrimidin]-6-yl)pyridin-2-yl)-10Hphenoxazine(PmPy-PXZ),enabling dual-TADF properties due to its key feature of conformational *** a pyridine bridge can greatly reduce the steric hindrance and facilitate dual-stable conformations in the ground state,where the quasi-axial(QA)forms ***,unlike previously reported TADF molecules with dual confirmations,both theoretical and experimental measurements show that not only the quasi-equatorial(QE)forms but also the QA forms exhibit distinct TADF characteristics,which can be attributed to an additional higher reverse intersystem crossing *** is the first time that dual-TADF properties of single molecules have been achieved based on conformational *** applications in“self-doping”organic light-emitting diode and biomedical imaging have further been *** these results show the good potential of such dual-band TADF emitters based on molecular conformational isomerization.

关键词： dual-thermally activated delayed fluorescence conformational isomerization organic light-emitting diode biomedical imaging self-doping