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Simulation of cohesive crack growth by a variable-node XFEM

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Frontiers of Structural and Civil Engineering 2020年第1期14卷 215-228页

作者： Weihua FANG Jiangfei WU Tiantang YU thanh-tung nguyen Tinh Quoc BUI Nanjing Automation Institute of Water Conservancy and Hydrology Nanjing 210012China Department of Engineering Mechanics Hohai UniversityNanjing 211100China Laboratory of Solid Structures University of LuxembourgLuxembourg L-1359Luxembourg Institute for Research and Development Duy Tan UniversityDa Nang City 550000Vietnam Department of Civil and Environmental Engineering Tokyo Institute of TechnologyTokyo 152-8552Japan

A new computational approach that combines the extended finite element method associated with variable-node elements and cohesive zone model is *** using a new enriched technique based on sign function,the proposed model using 4-node quadrilateral elements can eliminate the blending element *** also allows modeling the equal stresses at both sides of the crack in the crack-tip as assumed in the cohesive model,and is able to simulate the arbitrary crack-tip *** multiscale mesh technique associated with variable-node elements and the arc-length method further improve the efficiency of the developed *** performance and accuracy of the present approach are illustrated through numerical experiments considering both mode-I and mixed-mode fracture in concrete.

关键词： extended finite element method cohesive zone model sign function crack propagation

Prolonged post-thaw culture of embryos does not improve outcomes of frozen human embryo transfer cycles: A prospective randomized study

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Asian pacific Journal of Reproduction 2019年第6期8卷 260-266页

作者： Minh Tam Le Van Trung nguyen thanh tung nguyen MBlake EVans Thai thanh Thi nguyen Tam AnThi nguyen Dinh Duong Le Vu Quoc Huy nguyen Ngoc thanh Cao Micah J.Hill Department of Obstetrics and Gynecology Hue University of Medicine and PharmacyHue University06 Ngo Quyen StreetHueVietnam Center for Reproductive Endocrinology and Infertility Hue University of Medicine and PharmacyHue University06 Ngo Quyen StreetHueVietnam Department of Histology and Embryology Hue University of Medicine and PharmacyHue University06 Ngo Quyen StreetHueVietnam Walter Reed National Military Medical Center 8901 Rockville PikeBethesdaMD20889USA Department of Public Health Hue University of Medicine and PharmacyHue University06 Ngo Quyen StreetHueVietnam

Objective:To evaluate the impact of prolonged post-thaw embryos culture on pregnancy outcome during frozen embryo transfer ***:This prospective cohort study evaluated 324 thaw transfer cycles with 819 embryos from 269 patients at the Center for Reproductive Endocrinology and Infertility of Hue University Hospital in *** frozen embryo transfer cycles were divided into two groups at the time of thawing:the short culture group(2-hour post-thaw culture)and the overnight culture group(overnight culture for 18 h)before the embryo was transferred into the *** rates of embryo intact,grade A embryo at frozen and transfer time and continuing cleavage were *** clinical outcomes including serum beta-human chorionic gonadotropin,clinical pregnancy and implantation rate were evaluated after 14 days,4 weeks,6 weeks,respectively,after embryo ***:Human chorionic gonadotropin positive occurred in 39.5%of patients in the short culture group compared to 25.9%in the overnight culture group with risk difference(RD)=13.6%,relative risk(RR)=1.343,95%confidence interval(CI)1.085-1.663,P<*** pregnancy rate of the short culture group and overnight culture group was 33.3%and 24.1%,respectively(RD=9.2%,RR=1.242,95%CI 0.996-1.549,P=0.06)and the implantation rate in the short culture group and overnight culture group was 16.5%and 11.0%,respectively(RD=5.5%,RR=1.244,95%CI 1.046-1.479,P=0.01).In women of advanced age(≥35 years)and women who received 3 embryos,pregnancy outcomes were found to be significantly(P<0.05)higher in the short culture than in the overnight culture ***:The prolonged post-thaw culture period does not increase pregnancy outcome in comparison with the short culture.

关键词： Embryo vitrification Post-thaw culture Frozen embryo transfer Biochemical pregnancy rate Clinical pregnancy rate Implantation rate

Marker-Assisted Selection of Xa21 Conferring Resistance to Bacterial Leaf Blight in indica Rice Cultivar LT2

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Rice science 2018年第1期25卷 52-56页

作者： Hue Thi nguyen Quang Hong VU Tan Van MAI Thu Thi nguyen Lam Duc VU tung thanh nguyen Long Viet nguyen Hien Thu Thi VU Hue Thi NONG Trung nguyen DINH Nakano TOSHITSUGU Liet Van VU Crop Research and Development Institute Vietnam National University of Agriculture Trau Qui Gia Lam Hanoi 10000 Vietnam Faculty of Agronomy Vietnam National University of Agriculture Trau Qui Gia Lam Hanoi 10000 Vietnam Faculty of Biotechnology Vietnam National University of Agriculture Trau Qui Gia Lam Hanoi 10000 Vietnam Faculty of Land Management Vietnam National University of Agriculture Trau Qui Gia Lam Hanoi 10000 Vietnam Japan International Cooperation Agency 16 Phan Chu Trinh Hoan Kiem Hanoi 10000 Vietnam

Bacterial leaf blight of rice (BLB), caused by Xanthomonas oryzae pv. oryzae, is one of the most destructive diseases in Asian rice fields. A high-quality rice variety, LT2, was used as the recipient ***21, which carries the Xa21 gene, was used as the donor parent. The resistance gene Xa21 was introduced into LT2 by marker-assisted backcrossing. Three Xoo races were used to inoculate the improved lines following the clipping method. Eleven BC_3F_3 lines carrying Xa21 were obtained based on molecular markers and agronomic performance. The 11 lines were then inoculated with the three Xoo races. All the 11 improved lines showed better resistance to BLB than the recipient parent LT2. Based on the level of resistance to BLB and their agronomic performance, five lines (BC_3F_3 5.***.5.1, BC_3F_3 5.***.5.12, BC_3F_3 8.***.6.44, BC_3F_3 9.***.4.1 and BC_3F_3 9.***.4.23) were selected as the most promising for commercial release. These improved lines could contribute to rice production in terms of food security.

关键词： rice backcrossing bacterial leaf blight marker-assisted selection

Driver State Detection Based on Cardiovascular System and Driver Reaction Information Using a Graphical Model

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Journal of Transportation Technologies 2021年第2期11卷 139-156页

作者： thanh tung nguyen Hirofumi Aoki Anh Son Le Hirano Akio Kunimoto Aoki Makoto Inagami Tatsuya Suzuki Graduate School of Engineering Nagoya University Nagoya Japan Institute of Innovation for Future Society Nagoya University Nagoya Japan

Traffic accidents are mainly caused by human error. In an aging society, the number of accidents attributed to elderly drivers is increasing. One noteworthy reason for this is operation misapplication. Studies have been conducted on the use of human-machine interfaces (HMIs) to inform the driver when he or she makes an error and encourage appropriate actions. However, the driver state during the erroneous action has not been investigated. The purpose of this study is to clarify the difference in the driver’s state between normal and surprising situations in a misapplication scenario, utilizing multimodal information such as biometric information and driver operation. We found significant changes in the interaction of components between the normal and the surprised driving state. The results could provide basic knowledge for the future development of a driver assistance system and driver state estimation using data acquired from multiple sensors in the vehicle.

关键词： Human Engineering Driver Behavior Bio-Signal Safety

A combination of immunoadjuvant nanocomplexes and dendritic cell vaccines in the presence of immune checkpoint blockade for effective cancer immunotherapy

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Cellular & Molecular Immunology 2021年第6期18卷 1599-1601页

作者： Manh-Cuong Vo Seo-Yeon Ahn Tan-Huy Chu Saji Uthaman Shammer Pillarisetti tung nguyen thanh Uong Thangaraj Jaya Lakshmi Mihee Kim Ga-Young Song Sung-Hoon Jung Deok-Hwan Yang Jae-Sook Ahn Hyeoung-Joon Kim In-Kyu Park Je-Jung Lee Institute of Research and Development Duy Tan UniversityDanangVietnam Research Center for Cancer Immunotherapy Chonnam National University Hwasun HospitalHwasunJeollanamdoRepublic of Korea Department of Hematology-Oncology Chonnam National University Hwasun HospitalChonnam National University Medical SchoolGwangjuRepublic of Korea Department of Polymer Science and Engineering Chungnam National UniversityDaejeonRepublic of Korea Department of Biomedical Science Chonnam National University Medical SchoolGwangjuRepublic of Korea Department of Radiation Oncology Chonnam National University Hwasun HospitalChonnam National University Medical SchoolGwangjuSouth Korea View author publications

Nanovaccines are used as delivery platforms for antigens and adjuvants, which activate antigen-presenting cells (APCs) and enhance anticancer immune responses.1,2 Researchers have recently developed a self-assembled nanocomplex using a polysorbitol-co-PEI (PSPEI) polymer complexed with poly(I:C) (PIC). By binding to different surface proteins, this nanocomplex enhances the intracellular delivery of cargos and induces potent anticancer immune responses against melanoma cells.3 We have previously demonstrated that PD-1/PD-L1 blockade enhanced the efficacy of DC-based cancer immunotherapy.4,5 Moreover, the combination of nanomedicines and PD-L1 blockade has been reported to enhance CD8+ T cell activation and inhibit immunosuppressive cells within the tumor microenvironment.6 In the present study, we investigated the therapeutic efficacy of a combinatorial treatment comprising the immunoadjuvant nanocomplex PSPEI-PIC, a DC vaccine, and PD-L1 blockade in a murine colon cancer model.

关键词： adjuvant vaccines immunotherapy

Novel Deletion in Exon 7 of Betaine Aldehyde Dehydrogenase 2(BADH2)

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Rice science 2023年第2期30卷 104-112,I0020-I0030页

作者： VAN Quoc Giang HUYNH Ky nguyen Chau thanh tung nguyen Loc Hien nguyen van Manh nguyen Nhut thanh VO Cong thanh SWEE Keong Yeap College of Agriculture Can Tho UniversityCan Tho 92000Vietnam Department of Sciences and Technology of Long An Province Long An 850000Vietnam China-Association of Southeast Asian Nations College of Marine Sciences Xiamen University MalaysiaSepang 49000SelangorMalaysia

The fragrance of rice is one of the premium characteristics that breeders want to include in rice varieties due to the higher market value. Nucleotide deletions in exons 2(7 bp) and 7(8 bp) of Betaine Aldehyde Dehydrogenase 2(BADH2) are associated with fragrance in rice. In this study, a new 13 bp deletion in exon 7 of the BADH2 gene was discovered in the Nang Thom Cho Dao(NTCD) variety, and the mutation has been closely related to the genetic background of indica subspecies through the Bayesian phylogenetic approach and haplotype network analysis of the 3 000 Rice Genomes Project. In addition, a set of functional markers(EX07-13F, EX07-13RN, and EX07-13RM) identified the 13 bp deletion only within NTCD(no amplified band) compared with both non-aromatic and other aromatic rice varieties(110 bp band). The deletion of 13 bases instead of 8 bases in exon 7 of BADH2 caused a premature stop codon, which down-regulated the expression of the BADH2 transcript while associated with up-regulation of OsP5CS and the high amount of 2-acetyl-1-pyrroline. It is potential to use the deletion in exon 7 of the BADH2 gene as a novel marker for adulteration and breeding of fragrant rice varieties, particularly for NTCD.

关键词： novel deletion BADH2 fragrant rice functional marker

Structural and luminescent properties of (Eu,Tb) PO_4·H_2O nanorods/nanowires prepared by microwave technique

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Journal of Rare Earths 2011年第12期29卷 1170-1173页

作者： nguyen thanh Huong nguyen Duc Van Dinh Manh Tien Do Khanh tung nguyen thanh Binh Tran Kim Anh Le Quoc Minh Institute of Materials Science Vietnam Academy of Science and Technology University of Engineering and Technology National University HanoiVietnam

Nanowires/nanorods of europium/terbium orthophosphate monohydrate with Eu^3＋ concentration of 6, 11, and 20 at.% were prepared by microwave synthesis method. The effects of Eu^3＋ doping concentration on structure, morphology and optical properties of nanomaterials were also investigated. The results showed that, for all studied Eu^3＋ doping concentrations, a single-crystalline phase of rhabdophane-type （Eu,Tb）PO4·H2O nanowires/nanorods was obtained by using microwave heating of an aqueous solution of terbium（Ⅲ） nitrate, europium（Ⅲ） nitrate and NH4H2PO4 with pH=2. The length and width of these nanowires/nanorods ranged from 150 to 300 nm and from 10 to 50 nm, respectively. The evidence of energy transfer from Tb^3＋ to Eu^3＋ due to the energy overlap between the donor Tb^3＋ and the acceptor Eu^3＋was observed obviously via a significant enhancement in the luminescent intensity of Eu^3＋. Keywords：

关键词： microwave technique nanowires/nanorods energy transfer fluorescence spectroscopy rare earths

A Chemical Reactor Network for Oxides of Nitrogen Emission Prediction in Gas Turbine Combustor

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Journal of Thermal Science 2014年第3期23卷 279-284页

作者： nguyen thanh Hao Industrial University of HoChiMinh City

This study presents the use of a new chemical reactor network(CRN) model and non-uniform injectors to predict the NOx emission pollutant in gas turbine combustor. The CRN uses information from Computational Fluid Dynamics(CFD) combustion analysis with two injectors of CH4-air mixture. The injectors of CH4-air mixture have different lean equivalence ratio, and they control fuel flow to stabilize combustion and adjust combustor's equivalence ratio. Non-uniform injector is applied to improve the burning process of the turbine combustor. The results of the new CRN for NOx prediction in the gas turbine combustor show very good agreement with the experimental data from Korea Electric Power Research Institute.

关键词： Chemical Reactor Networks (CRN) Computational Fluid Dynamics (CFD) Perfectly Stirred Reactor (PSR) Plug Flow Reactor (PFR) Gas Turbine Combustor Oxides of Nitrogen Emission (NOx).

Anti‐sloshing control:Flatness‐based trajectory planning and tracking control with an integrated extended state observer

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IET Cyber-Systems and Robotics 2024年第3期6卷 31-48页

作者： Khanh nguyen Viet Minh Do Duc thanh Cao Duc tung Lam nguyen School of Electrical and Electronic Engineering Hanoi University of Science and TechnologyHanoiVietnam Vietnam Maritime University HaiphongVietnam

The phenomenon of sloshing causes a significantly negative impact on a wide range of industries.A time‐optimal flatness‐based trajectory planning and Lyapunov‐based model predictive control(LMPC)is proposed for trajectory tracking of a transmitting cylindrical container filled with ***,this research presents an equivalent discrete model based on a mass‐spring‐damper ***,after the flatness of the adopted non‐linear model for 2D is established,time‐optimal trajectories are introduced.A control method called LMPC is shown to solve the problem of orbital tracking,which allows setting limits for state *** addition,to ensure system performance,a linear extended state observer(LESO)is integrated to cope with system ***,the efficiency of the proposed approach for liquid sloshing suppression and tracking is illustrated by simulations.

关键词： control dynamic model motion planning