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Direct-Seeded Rice: Genetic Improvement of Game-Changing Traits for better Adaption

Rice science 2024年第4期31卷 417-433页

作者： Priyanka NEGI Jagadish RANE Rajendra Sadashiv WAGH tukaram jayaram.b.or Dipti Digambar GODSE Priyanka JADHAV C.ANILKUMAR Dasari SREEKANTH K.SAMMI REDDY Sharad Ramrao GADAKH K.M.bORAIH C.b.HARISHA P.S.bASAVARAJ Indian Council of Agricultural Research(ICAR)-National Institute of Abiotic Stress Management Baramati 413115India Mahatma Phule Krishi Vidyapeeth Rahuri 413722India ICAR-Central Institute for Arid Horticulture Bikaner 334006India ICAR-National Rice Research Institute Cuttack 753006India ICAR-Directorate of Weed Research Jabalpur 482004India Dr.Panjabrao Deshmukh Krishi Vidyapeeth Akola 444104India

The sustainability of rice production continues to be a subject of uncertainty and inquiry attributed to shifts in climatic conditions. In light of the impending climate change crisis and the high labor and water costs accompanying it, direct-seeded rice(DSR) is unquestionably one of the most practical solutions. Despite its resource and climate-friendly advantages, early maturing rice faces weed competitiveness and seedling establishment challenges. Resolving these issues is crucial for promoting its wider adoption among farmers, presenting it as a more effective sustainable rice cultivation method globally. Diverse traditional and contemporary breeding methods are employed to mitigate the limitations of the DSR approach, leveraging advanced techniques such as speed breeding and genome editing. Focusing on key traits like mesocotyl length elongation, early seedling vigor, root system architecture, and weed competitiveness holds promise for transformative improvements in DSR adaptation at a broader scale within farming communities. This review aims to summarize how these features contribute to increased crop production in DSR conditions and explore the research efforts focusing on enhancing DSR adaptation through these traits. Emphasizing the pivotal role of these game-changing traits in DSR adaptation, our analysis sheds light on their potential transformative impact and offers valuable insights for advancing DSR practices.

关键词： climate change direct-seeded rice aerobic rice early vigor trait

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Machine Learning-based Pruning Technique for Low Power Approximate Computing

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Computer Systems Science & Engineering 2022年第7期42卷 397-406页

作者： b.Sakthivel K.jayaram N.Manikanda Devarajan S.Mahaboob basha S.Rajapriya Department of Electronics and Communication Engineering Madurai Institute of Engg and TechnologySivagangaiTamilnadu630611India Pilecubes India Pvt Ltd. ChennaiTamilnaduIndia Department of Electronics and Communication Engineering Malla Reddy Engineering College(Autonomous)Secunderabad500100India Department of Electronics and Communication Engineering R.M.K.Engineering CollegeKavaraipettaiChennaiTamil Nadu601206India Department of Electronics and Communication Engineering K Ramakrishnan College of EngineeringKariyamanickam RdTamil Nadu621112India

Approximate Computing is a low power achieving technique that offers an additional degree of freedom to design digital *** is one of the types of approximate circuit design technique which removes logic gates or wires in the circuit to reduce power consumption with minimal insertion of *** this work,a novel machine learning(ML)-based pruning technique is introduced to design digital *** machine-learning algorithm of the random forest deci-sion tree is used to prune nodes selectively based on their input *** addi-tion,an error compensation value is added to the original output to reduce an error *** results proved the efﬁciency of the proposed technique in terms of area,power and error *** to conventional pruning,proposed ML pruning achieves 32%and 26%of the area and delay reductions in 8*8 multi-plier *** power image processing algorithms are essential in various applications like image compression and enhancement *** real-time evaluation,proposed ML optimized pruning is applied in discrete cosine transform(DCT).It is a basic element of image and video processing *** results on benchmark images show that proposed pruning achieves a very good peak signal-to-noise ratio(PSNR)value with a considerable amount of energy savings compared to other methods.

关键词： Machine learning pruning approximate computing PSNR

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A Recyclable and Highly Effective ZnO-beta Zeolite as a Catalyst for One-pot Three-Component Synthesis of Tetrahydrobenzo[b]pyrans

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Chinese Journal of Chemistry 2011年第1期29卷 199-202页

作者： Katkar, Santosh Shriram Lande, Machhindra Karbhari Arbad, balasaheb Ramrao Gaikwad, Suresh tukaram Department of Chemistry Dr. Babasaheb Ambedkar Marathwada University Aurangabad-431004 Maharashtra India

4H-benzo[b]pyrans was synthesized under reflux condition in ethanol via condensation of benzaldehyde, malononitrile and dimedone with ZnO-beta zeolite as an inexpensive and effective catalyst. The key features of the reported protocols are good to excellent yields, short reaction time and recovery and reusability of catalytic material.

关键词： heterogeneous 4H-benzo[b]pyrans ZnO-beta zeolite multicomponent cyclocondensation

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Multilevel resistive switching and synaptic plasticity of nanoparticulated cobaltite oxide memristive device

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Journal of Materials Science & Technology 2021年第19期78卷 81-91页

作者： tukaram D.Dongale Atul C.Khot Ashkan V.Takaloo Kyung Rock Son Tae Geun Kim School of Electrical Engineering Korea University.Anam-ro 145.Seongbuk-guSeoul 02841Republic of Korea School of Nanoscience and biotechnology Shivaji UniversityKolhapur 416004India

Multilevel resistive switching(RS)is a key property to embrace the full potential of memristive devices for non-volatile memory and neuromorphic computing *** this study,we employed nanoparticulated cobaltite oxide(Co_(3)O_(4))as a model material to demonstrate the multilevel RS and synaptic learning capabilities because of its multiple and stable redox state *** Pt/Co_(3)O_(4)/Pt memristive device exhibited tunable RS properties with respect to different voltages and compliance currents(CC)without the electroforming *** is,the device showed voltage-dependent RS at a higher CC whereas CC-dependent RS was observed at lower *** device showed four different resistance states during endurance and retention measurements and non-volatile memory results indicated that the CC-based measurement had less ***,we investigated the basic and complex synaptic plasticity properties using the analog current-voltage characteristics of the Pt/Co_(3)O_(4)/Pt *** particular,we mimicked the potentiation–depression and four-spike time-dependent plasticity(STDP)rules such as asymmetric Hebbian,asymmetric anti-Hebbian,symmetric Hebbian,and symmetric antiHebbian learning *** results of the present work indicate that the cobaltite oxide is an excellent nanomaterial for both multilevel RS and neuromorphic computing applications.

关键词： Multilevel resistive switching Synaptic plasticity STDP Cobaltite oxide Memristive device

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2D Ti_(3)C_(2)T_(x)MXene-derived self-assembled 3D TiO_(2)nanoflowers for nonvolatile memory and synaptic learning applications

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Journal of Materials Science & Technology 2023年第19期150卷 1-10页

作者： Atul C.Khot tukaram D.Dongale Kiran A.Nirmal Jayan K.Deepthi Santosh S.Sutar Tae Geun Kim School of Electrical Engineering Korea UniversityAnam-ro 145Seongbuk-guSeoul 02841Republic of Korea Computational Electronics and Nanoscience Research Laboratory School of Nanoscience and BiotechnologyShivaji UniversityKolhapur 416004India Rajagiri School of Engineering and Technology(Autonomous) Rajagiri ValleyKakkanadKochiKerala 682039India Yashwantrao Chavan School of Rural Development Shivaji UniversityKolhapur 416004India

Two-dimensional(2D)semiconducting materials and transition-metal oxides are promising materials for nonvolatile memory and brain-inspired neuromorphic computing ***,it remains chal-lenging to obtain high-quality stacked 2D films with low energy consumptions(or drive currents)be-cause of their high interfacial *** this study,we synthesized 2D Ti_(3)C_(2)T_(x)MXene-derived three-dimensional(3D)TiO_(2)nanoflowers(NFs)as a feasible resistive switching(RS)material with outstanding electronic properties and synaptic learning *** electrical and optical characteristics of the synthesized material were determined through density functional theory *** measure-ments of the Al/Ti_(3)C_(2)T_(x)-TiO_(2)NF/Pt memory device indicated the occurrence of forming-free switching phenomena with extremely low switching voltages(0.68-0.53 V),stable ON/OFF ratio(2.3×103),and retention greater than 105 *** Holt-Winters exponential smoothing technique was used for mod-eling and predicting the switching voltages of the RS *** mechanism underlying the reliable RS was confirmed by observing the dense conductive filaments through conductive atomic force ***,the 2D Ti_(3)C_(2)T_(x)MXene-derived 3D TiO_(2)NF-based RS device mimicked the po-tentiation/depression and spike-time-dependent plasticity of a biological ***,a convolutional neural network was implemented based on the observed synaptic weights of Al/Ti_(3)C_(2)T_(x)-TiO_(2)NF/Pt for image-edge detection.

关键词： MXene Ti_(3)C_(2)T_(x)-TiO_(2)nanoflowers Resistive switching Synaptic learning Density functional theory Time-series analysis

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新型糖氨基酸类化合物的合成研究

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化学学报 2015年第7期73卷 699-704页

作者：汪学彬王晓丽胡静王兆亚 Pimpalpalle tukaram M Linker Torsten 尹健江南大学生物工程学院糖化学与生物技术教育部重点实验室无锡214122 江南大学无锡医学院无锡214122 Department of Chemistry University of Potsdam

糖氨基酸(sugar amino acids,SAAs)是一类同时含有氨基和羧基的糖类衍生物,具有糖和氨基酸的结构特征和化学反应特性,常作为多功能合成砌块用于组合化学的研究、糖模拟物和多肽模拟物的构建等.因此,该类化合物的设计与合成受到国内外化... 详细信息

糖氨基酸(sugar amino acids,SAAs)是一类同时含有氨基和羧基的糖类衍生物,具有糖和氨基酸的结构特征和化学反应特性,常作为多功能合成砌块用于组合化学的研究、糖模拟物和多肽模拟物的构建等.因此,该类化合物的设计与合成受到国内外化学家的持续关注.在本文中,我们发展了一种简单、高效的合成新型糖氨基酸的方法,从廉价易得的3,4,6-O-三乙酰基-D-葡萄糖烯和3,4,6-O-三乙酰基-D-半乳糖烯出发,在硝酸铈铵(CAN)的作用下通过一步自由基加成反应分别得到2-C-二羧酸酯类化合物gluco-2和galacto-2,再经过脱羧、脱乙酰、碘代、叠氮化钠取代和一锅法还原氨化反应,以最短直线步骤6步实现了糖氨基酸gluco-7(总收率34%)和galacto-7(总收率19%)的合成.所有合成的化合物均经过IR,1H NMR,13C NMR和HRMS的表征.

关键词：糖氨基酸糖烯自由基加成一锅法反应合成

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硬毛巴豆减弱链脲佐菌素诱导大鼠的神经炎症

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数字中医药(英文) 2023年第3期6卷 295-306页

作者： Prakash Ramakrishnan jayaram Rajangam binoy Varghese Cherian Jose Prakash Dharmian Department of Pharmacology Crescent School of PharmacyB.S.Abdur Rahman Crescent Institute of Science and TechnologyChennaiTamil Nadu 600048India Department of Pharmacology Shri Venkateshwara College of PharmacyPondicherryTamil Nadu 605001India Department of Pharmaceutical Chemistry Saveetha College of PharmacyChennaiTamil Nadu 602117India Department of Pharmaceutics Crescent School of PharmacyB.S.Abdur Rahman Crescent Institute of Science and TechnologyChennaiTamil Nadu 600048India

目的本研究旨在探讨硬毛巴豆(CH)提取物在链脲佐菌素(STZ)大鼠中的神经保护作用。方法(1)亚慢性毒性试验包括24只成年大鼠,雌雄不限,体重160~200 g,分为4组,每组6只。第1组大鼠给予二甲基亚砜(DMSO)与生理盐水混合物;第2、3、4组大鼠灌... 详细信息

目的本研究旨在探讨硬毛巴豆(CH)提取物在链脲佐菌素(STZ)大鼠中的神经保护作用。方法(1)亚慢性毒性试验包括24只成年大鼠,雌雄不限,体重160~200 g,分为4组,每组6只。第1组大鼠给予二甲基亚砜(DMSO)与生理盐水混合物;第2、3、4组大鼠灌胃给药硬毛巴豆甲醇提取物(MECH),剂量分别为100、200和400 mg/kg,连续28天。将功能观察组合和自发活动分级作为其神经行为活动的一部分,并对脑区(如皮质和海马)进行神经病理学异常分析。(2)研究动物体重为160~200 g的成年雄性Wistar大鼠,分为5组,每组6只,包括对照组(Ⅰ)、STZ组(Ⅱ)、多奈哌齐组(Ⅲ)、MECH组(100 mg/kg,Ⅳ)和MECH组(200 mg/kg,Ⅴ)。第Ⅰ组大鼠口服柠檬酸盐缓冲液和DMSO生理盐水混合物(14天)。第Ⅱ组大鼠在第1天和第3天侧脑室注射链脲佐菌素(3 mg/kg,双侧ICV-STZ),随后给予生理盐水DMSO混合物(14天)。第Ⅲ、Ⅳ和Ⅴ组大鼠在第1天和第3天给予STZ,随后口服多奈哌齐[3 mg/(kg·d)]和MECH[100和200 mg/(kg·d)](14天)。检测大鼠Morris水迷宫(MWM)和被动回避试验(PAT)等学习记忆指标。完成行为学实验后处死动物,取脑,用紫外可见分光光度计测定乙酰胆碱酯酶(AChE)、脂质过氧化(LPO)、谷胱甘肽(GSH)和超氧化物歧化酶(SOD)水平。使用总荧光发射光谱法测定caspase-3水平。通过酶联免疫吸附测定(ELISA)检测β淀粉样蛋白(Aβ)水平,同时对CA1海马区进行组织病理学分析。结果(1)亚慢性毒性结果显示,各组MECH大鼠的旷场试验参数(包括线交叉、直立、进入中广场、排便或排尿)无显著差异(P>0.05)。组织病理学结果显示,与对照组大鼠相比,经过MECH治疗的大鼠两个区域的神经元细胞中均未产生任何病变和炎症。(2)研究主要发现STZ处理大鼠在学习和记忆参数受损显著增加(P<0.001),AChE、caspase-3、Aβ(1-40和1-42)和LPO水平均显著升高(P<0.001),且SOD和GSH水平显著降低(P<0.01)。此外,在海马区发现神经元损伤。相反,STZ诱导大鼠的行为和生化损伤与MECH治疗呈剂量依赖性降低。结论MECH通过其抗氧化作用可显著预防STZ诱导的记忆缺陷,胆碱能功能的恢复可能是行为改善的原因。因此,MECH可能治疗包括阿尔茨海默病在内的认知障碍。

关键词：神经炎症硬毛巴豆阿尔茨海默病链脲佐菌素脑室内

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手法小切口白内障术联合小梁切除治疗POAG合并白内障(英文)

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国际眼科杂志 2012年第9期12卷 1609-1613页

作者： Vasanthi b. Kotian jayaram Shetty Vijay Pai Uma Kulkarni Subramanya bhat Harish Shetty Ananda bangera Nitte大学 K.S.Hegde医学科学院眼科 Yenepoya大学 Yenepoya医学科学院眼科 Nitte大学 K.S.Hegde医学科学院

目的:白内障手术技术在近年已经得到了很大提高。本文提出了一项创新且操作简便的隧道内小梁切除术,并发症少,用于治疗白内障合并原发性开角型青光眼(primary open angle glaucoma,POAG)。方法:对于纳入该前瞻性、非随机性临床研究的103... 详细信息

目的:白内障手术技术在近年已经得到了很大提高。本文提出了一项创新且操作简便的隧道内小梁切除术,并发症少,用于治疗白内障合并原发性开角型青光眼(primary open angle glaucoma,POAG)。方法:对于纳入该前瞻性、非随机性临床研究的103例108眼白内障合并POAG患者行手法小切口白内障手术(manual small incision cataract surgery,MSICS)联合隧道内小梁切除术。随访6mo,依据气泡的解剖学外形及其功能对手术疗效进行评估。结果:术后第1d,隧道内切口组的平均眼压(intraocular pressure,IOP)为11.4±3.1mmHg(P=0.012),术后第2d的平均IOP为10.3±3.5mmHg(P=0.065)。隧道内切口组的浅前房和虹膜角膜接触明显减少。结论:巩膜隧道切口小梁切除术("scleral tunnel incision"-trabeculectomy,STIT)的眼压在术后6mo平稳降低。STIT相对安全,类似过多房水外流的早期并发症比传统小梁切除术(conventional trabeculectomy,CT)少。

关键词：隧道内小梁切除术原发性开角型青光眼传统小梁切除术白内障

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Forced Degradation Studies on Sodium Picosulfate and Separation of 15 Process Related Impurities/Degradants by HPLC

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American Journal of Analytical Chemistry 2020年第11期11卷 363-375页

作者： Palakben Patel Kishore Kumar Hotha Deenal Patel jayaram Kamma Abhinandana Gudimella Saikrishna bompelliwar Subathra Ramamoorthy Analytical Research & Development Lupin Somerset NJ USA

A selective, precise and stability-indicating, high performance liquid chromatographic method was developed for the analysis of active ingredient sodium Picosulfate and forced degradation behavior was studied. The current article describes forced degradation behavior of the Sodium Picosulfate drug substance in detail by analyzing 15 process related/degradants in a single HPLC method under ICH recommended stressed conditions. Mobile phase comprised of 0.01 M of Disodium hydrogen phosphate and 0.01 M of potassium phosphate monobasic buffer and 1 mL of triethyl amine in 1000 mL water adjusted to pH 7.5 with 10% phosphoric acid. Acetonitrile was used as Mobile Phase b. The separation was achieved on a gradient method. The reversed phase chromatography was performed in Hypersil bDS C18 5.0 μm, 4.6 × 250 mm column maintained at temperature 35°C. Injection volume was 60 μL. Milli-Q water used as diluent. The mobile phase was pumped at 0.9 mL/min-1. The eluted compounds were monitored at 220 nm. Secondary wavelength of the 263 nm was studied to check any further degradants during the forced degradation studies. New additional degradants Sodium Picosulfate benzyl alcohol Impurity and N oxide degradations were discussed and studied during the forced degradation to understand the chemical stability of the drug substance.

关键词： Sodium Picosulfate Chemical Degradation Forced Degradation benzyl Alcohol Impurity

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