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Biomedical and Environmental Sciences 2018年第9期31卷 700-704页

作者： HU Zong Shan ZHAO Zhi Hui TSENG Chang-Chun LI Jie man Gene Chi-Wai LAM tsz-Ping QIU Yong CHENG Chun-Yiu Jack ZHU Ze Zhang LIU Zhen Department of Orthopaedics and Traumatology Faculty of Medicine Prince of Wales Hospital The Chinese University of Hong Kong Shatin New Territories 999077 Hong Kong China The Joint Scoliosis Research Center of the Chinese University of Hong Kong and Nanjing University Hong Kong 999077 China Department of Spine Surgery the Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjing 210008 Jiangsu China

The objective of this study was to characterize sympathetic nervous system （SNS） activity in girls with adolescent idiopathic scoliosis （AIS） and investigate the correlation of such activity with body weight and bone mass. Fifty-eight girls with AIS and 21 healthy controls were recruited. Abnormal growth pattern （lower weight, lower body mass index （BMI）, and longer arm span） and significantly increased adrenaline （AD） level, norepinephrine （NE） level, and low-frequency （LF） were found in girls with AIS. Circulating AD level, NE level, and LF power were negatively correlated with body weight and BMI but significantly correlated with bone quality.

关键词： AIS A Cross-sectional Study SNS BMD

Novel travelling wave structures:few-cyclepulse solitons and soliton molecules

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Communications in Theoretical Physics 2021年第2期73卷 23-29页

作者： Zitong Chen man Jia School of Physical Science and Technology Ningbo UniversityNingbo 315211China

We discuss a fifth order KdV(FOKdV)equation via a novel travelling wave method by introducing a background *** show that the background term plays an essential role in finding new abundant travelling wave structures,such as the soliton induced by negative background,the periodic travelling wave excited by the positive background,the few-cycle-pulse(FCP)solitons with and without background,the soliton molecules excited by the *** FCP solitons are first obuained for the FOKdV equation.

关键词： New travelling method a fifth order KdV equation solitons induced by background few-cycle-pulse solitons soliton molecules

Relationship between high dietary fat intake and Parkinson’s disease risk: a meta-analysis

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Neural Regeneration Research 2019年第12期14卷 2156-2163页

作者： Yan Qu Xi Chen man-man Xu Qiang Sun Department of Physiology School of Basic Medicine Qingdao University Qingdao Shandong Province China Intensive Care Unit The Affiliated Hospital of Qingdao University Qingdao Shandong Province China

OBJECTIVE: To assess whether dietary fat intake influences Parkinson’s disease risk. DATA SOURCES: We systematically surveyed the Embase and PubMed databases, reviewing manuscripts published prior to October 2018. The following terms were used:(“Paralysis agitans” OR “Parkinson disease” OR “Parkinson” OR “Parkinson’s” OR “Parkinson’s disease”) AND (“fat” OR “dietary fat” OR “dietary fat intake”). DATA SELECTION: Included studies were those with both dietary fat intake and Parkinson’s disease risk as exposure factors. The Newcastle-Ottawa Scale was adapted to investigate the quality of included studies. Stata V12.0 software was used for statistical analysis. OUTCOME MEASURES: The primary outcomes included the relationship between high total energy intake, high total fat intake, and Parkinson’s disease risk. The secondary outcomes included the relationship between different kinds of fatty acids and Parkinson’s disease risk. RESULTS: Nine articles met the inclusion criteria and were incorporated into this meta-analysis. Four studies scored 7 and the other five studies scored 9 on the Newcastle-Ottawa Scale, meaning that all studies were of high quality. Meta-analysis results showed that high total energy intake was associated with an increased risk of Parkinson’s disease (P = 0.000, odds ratio (OR)= 1.49, 95% confidence interval (CI): 1.26–1.75);in contrast, high total fat intake was not associated with Parkinson’s disease risk (P = 0.123, OR = 1.07, 95% CI: 0.91–1.25). Subgroup analysis revealed that polyunsaturated fatty acid intake (P = 0.010, OR = 1.03, 95% CI: 0.88–1.20) reduced the risk of Parkinson’s disease, while arachidonic acid (P = 0.026, OR = 1.15, 95% CI: 0.97–1.37) and cholesterol (P = 0.002, OR = 1.09, 95% CI: 0.92–1.29) both increased the risk of Parkinson’s disease. Subgroup analysis also demonstrated that, although the results were not significant, consumption of n-3 polyunsaturated fatty acids (P = 0.071, OR = 0.88, 95% CI: 0.73–1.05),α-linolenic ac

关键词： nerve regeneration dietary fat Parkinson's disease risk meta-analysis total energy intake polyunsaturated fatty acids arachidonic acid cholesterol α-linolenic acid linoleic acid n-3/n-6 polyunsaturated fatty acid intake ratio monounsaturated fatty acids neural regeneration

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融合前缀调优和提示学习的仇恨言论检测方法

计算机科学与探索 2025年第1期19卷 97-106页

作者：徐磊胡亚豪陈满陈军潘志松中国人民解放军陆军工程大学指挥控制工程学院南京210000

随着网络社交平台的发展,网络暴力的危害性日益凸显,其中仇恨言论作为网络暴力的一种表现形式,对其检测方法的研究有助于构建一个健康的互联网环境。然而,一方面先前的仇恨言论检测方法主要依赖于人工监管和关键词过滤,这些方法存在人... 详细信息

随着网络社交平台的发展,网络暴力的危害性日益凸显,其中仇恨言论作为网络暴力的一种表现形式,对其检测方法的研究有助于构建一个健康的互联网环境。然而,一方面先前的仇恨言论检测方法主要依赖于人工监管和关键词过滤,这些方法存在人工成本高且分类效果不佳的问题;另一方面,在互联网平台的监管下,仇恨言论的表达也变得更加含蓄、隐蔽,这对检测模型的文本理解能力提出了更高的要求。以ChatGPT为代表的大模型为仇恨言论检测任务提供了新的可能性,受其在各项下游任务中出色表现的启发,提出了一种融合前缀调优和提示学习的仇恨言论检测方法P-Prompt。利用前缀调优方法将大模型在相关数据集上进行微调,同时结合提示学习方法使模型能够识别并关注待检测文本中的仇恨言论词汇,从而进一步提升模型对仇恨言论的识别能力。实验结果验证了大模型在仇恨言论检测任务的有效性,与传统方法相比P-Prompt方法在仇恨言论检测的二分类和多分类任务中各项评价指标都取得了较明显的提升。

关键词：仇恨言论检测大语言模型前缀调优提示学习

Team behavioral integration links team interdependence with team performance: an empirical investigation in R&D teams

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Frontiers of Business Research in China 2019年第2期13卷 193-211页

作者： Xiaomeng Zhang kwong Kwan Cheung Kong Graduate School of Business Beijing China School of Economics and management Tongji University 1239 Siping Road Shanghai 200092 China

Drawi ng on the input-mediator (a blend of team process and emerge nt state)- output (IMO) framework, we develop a conceptual model in which team behavioral integration is conceived of as a team-level mediator that links team interdependence (input) with team performance (output). Using a three-wave research design, we test the hypothesized model with the data of 102 R&D teams from three information technology compa nies in China. Results indicate that team in terdependence positively influences team behavioral integration, and that team behavioral integration positively affects team performance. In addition, team behavioral integration is found to mediate the relationship between team interdependence and team performance. The theoretical and man agerial implicatio ns of these results are discussed.

关键词： Team interdependenee Team behavioral integration Team performance Top management teams Input-mediator-outcome framework R&D teams

Robust fault detection of piecewise affine ARX systems

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Journal of Control and Decision 2020年第3期7卷 276-285页

作者： Young-man Kim School of Engineering Liberty University1971 University Blvd.LynchburgVAUSA

In this paper,l1 regularisation-based robust fault detection technique for PWARX(PieceWise affine Auto Regressive eXogenous)systems is *** problem is formulated in convex optimisation form using l1 regularisation hence,global solution can be *** regularisation constant plays a key role for finding the number of *** MSE(mean square error)value between actual system and its model under no fault is used as a threshold for tracking dynamics change and detecting *** simplicity of turning only one parameter(regularisation constant)outstands this approach from *** proposed algorithm also shows the capability of separating the dynamics change from additive fault under *** illustration concludes this proposal by demonstrating its effectiveness.

关键词： Piecewise affine ARX fault detection regularisation convex optimisation sparsity

Deciphering fungal metabolon coupling tandem inverse-electrondemand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids

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Science China Chemistry 2025年第01期 288-296页

作者： Shuai Liu Wen-Qiang Xu Ying-Tong Di man-Cheng Tang Ding-Kang Chen Ming-Ming Cao Yao-Wen Chang Hong-Yu Tang Chun-Mao Yuan Jun-Bo Yang Zhi-Li Zuo Han Guo Zi-Fei Xu Ying Zeng Yun-Dong Wu Xiao-Jiang Hao Key Laboratory of Phytochemistry and Natural Medicines (Chinese Academy of Sciences) Kunming Institute of Botany Chinese Academy of Sciences University of Chinese Academy of Sciences Lab of Computational Chemistry and Drug Design State Key Laboratory of Chemical Oncogenomics Peking University Shenzhen Graduate School Shenzhen Bay Laboratory State Key Laboratory of Microbial Metabolism School of Life Sciences & Biotechnology Shanghai Jiao Tong University State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University Molecular Biology Experimental Center Germplasm Bank of Wild Species in Southwest China Kunming Institute of Botany Chinese Academy of Sciences Yunnan Key Laboratory for Wild Plant Resources Kunming Institute of Botany Chinese Academy of Sciences Research Unit of Chemical Biology of Natural Anti-Virus Products Chinese Academy of Medical Sciences

In the intricate process of natural product biosynthesis, a metabolon can enhance metabolic flux by associating sequential enzymes. A fungal metabolon, comprising of flavin-dependent monooxygenase Spe F and P450 monooxygenase Spe G, is identified in the biosynthesis of spiro polycyclic alkaloids(+)-notoamide B and its diastereomer(+)-versicolamide B. Using notoamide E as a substance, Spe F/Spe G metabolon can control the stereoselectivity of its 2,3-epoxidation, followed by hydrogen atom ion at C-17 to generate reactive epoxide tau-m A with dienyl iminium unit. Subsequently,(+)-notoamide B and(+)-versicolamide B are produced via tandem nonenzymatic inverse-electron-demand Diels-Alder reaction and semipinacol rearrangement. This provides the first example of metabolon in the biosynthesis of spiro-prenylated indole alkaloids.

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Influence of the Acoustic Liner in Large Eddy Simulation of Longitudinal Thermoacoustic Instability in a Model Annular Combustor

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Journal of Thermal Science 2024年第2期33卷 710-724页

作者： MENG Sheng ZHANG man GAO Yi AECC Commercial Aircraft Engine Co. Ltd.Shanghai200241China School of Aeronautics and Astronautics Shanghai Jiao Tong UniversityShanghai200240China

Although extensive efforts have been made to dampen the thermoacoustic instability,successfully controlling the pressure oscillations in modern gas turbines or aeroengines remains *** influence of the acoustic liner on the longitudinal thermoacoustic mode in a model annular combustor is investigated by Large Eddy Simulation(LES) in this *** result of the self-excited longitudinal thermoacoustic instability without the liner agrees well with the frequency and acoustic analysis of the pressure mode based on experimental *** different bias flow velocities of the liner located downstream of the combustor are then *** results reveal that the existence of the liner influences not only the acoustic field but also the flow *** the bias velocity is large,it leads to intense turbulence-induced fluctuations,and the pressure oscillation is modulated *** shows that the weak coupling between flow and pressure oscillations plays a significant role in the onset of the intermittency of a thermoacoustic *** on the dynamic analysis of the thermoacoustic system with the acoustic liner,this intermittency is caused by the influence of the flow field on the flame-acoustic ***,a low-order modeling method based on Van der Pol(VdP) oscillator with additive stochastic forcing is conducted to reproduce the evolving dynamics of the thermoacoustic *** the numerical cases demonstrated in this work are relatively simpler than those in a practical combustion system,the results are helpful for us to understand the effect of the acoustic liner and show the attractive potential to apply this device to suppress thermoacoustic instability.

关键词： thermoacoustic instability acoustic liner Large Eddy Simulation low-order modeling

Does the gamma-ray signal from the central Milky Way indicate Sommerfeld enhancement of dark matter annihilation?

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Research in Astronomy and Astrophysics 2016年第10期16卷 116-120页

作者： man-Ho Chan Department of Science and Environmental Studies The Education University of Hong Kong

Recently, some studies showed that the GeV gamma-ray excess signal from the central Milky Way can be explained by the annihilation of -40 GeV dark matter through the bb channel. Based on the morphology of the gamma-ray flux, the best-fit inner slope of the dark matter density profile is γ = 1.26. However, recent analyses of the Milky Way dark matter profile favor γ = 0.6 - 0.8. In this article, we show that the GeV gamma-ray excess can also be explained by the Sommerfeld-enhanced dark matter annihilation through the bb channel with γ = 0.85 - 1.05. We constrain the parameters of the Sommerfeld-enhanced annihilation by using data from Fermi-LAT. We also show that the predicted gamma-ray fluxes emitted from dwarf galaxies generally satisfy recent upper limits on gamma-ray fluxes detected by Fermi-LAT.

关键词： (cosmology): dark matter

Adaptive control of nonlinear systems with severe uncertainties in the input powers

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Science China(Information Sciences) 2021年第1期64卷 227-238页

作者： Linzhen YU Yungang LIU Yongchao man School of Control Science and Engineering Shandong University

In this study, we discuss global adaptive stabilization for a class of uncertain nonlinear *** input powers of the system are unknown, and the upper bound and the nonzero lower bound are not known in advance. This suggests that the system suffers from severe uncertainties with respect to the input powers when compared with the related literature, which would considerably challenge the control design. The switching-based strategy can compensate for severe system uncertainties, especially new types of uncertainties, including those associated with the input powers. Herein, a switching adaptive controller is successfully designed to ensure that the resulting closed-loop system states are globally bounded and ultimately converge to the origin(the equilibrium point). The proposed controller is extended to the systems with unknown control directions by redefining the involved switching sequences. A simulation example demonstrates the effectiveness of the proposed switching adaptive controller.

关键词： nonlinear systems severe uncertainties global stabilization unknown input powers switching adaptive control