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Journal of Semiconductors 2019年第1期40卷 63-69页

作者： tsung-han yang Houqiang Fu Hong Chen Xuanqi Huang Jossue Montes Izak Baranowski Kai Fu Yuji Zhao School of Electrical Computer and Energy Engineering Arizona State University

Beta-phase gallium oxide(β-Ga_2O_3) Schottky barrier diodes were fabricated on highly doped single-crystal substrates,where their temperature-dependent electrical properties were comprehensively investigated by forward and reverse current density – voltage and capacitance – voltage characterization. Both the Schottky barrier height and the ideality factor showed a temperature-dependence behavior, revealing the inhomogeneous nature of the Schottky barrier interface caused by the interfacial defects. With a voltage-dependent Schottky barrier incorporated into thermionic emission theory, the inhomogeneous barrier model can be further examined. Furthermore, the reverse leakage current was found to be dominated by the bulk leakage currents due to the good material and surface quality. Leakage current per distance was also obtained. These results can serve as important references for designing efficient β-Ga_2O_3 electronic and optoelectronic devices on highly doped substrates or epitaxial layers.

关键词： gallium oxide Schottky barrier diode power electronics wide bandgap material

Infectious Spondylitis-Associated Staphylococcus aureus with Virulence Gene pvl or tst Causes More Necrosis than Apoptosis in Human Alveolar Basal Epithelial Cell Line A549

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Advances in Microbiology 2016年第7期6卷 479-488页

作者： tsung-Jen Huang Chi-han Lee Meng-Huang Wu Yen-Yao Li tsung han yang Chin-Chang Cheng Ching-Yu Lee Chih-Cheng Lu Chishih Chu Department of Orthopedic Surgery Chang Gung Memorial Hospital Chiayi Branch Taiwan College of Medicine Chang Gung University Taiwan Department of Orthopedic Surgery Taipei Medical University Hospital Taiwan School of Medicine Taipei Medical University Taiwan Department of Microbiology Immunology and Biopharmaceutics National Chiayi University Taiwan Department of Laboratory Medicine Chang Gung Memorial Hospital Linkou Branch Taiwan

Methicillin-sensitive and resistant Staphylococcus aureus (MSSA and MRSA, respectively) can cause non-tuberculosis infectious spondylitis. In 43 cases of bacterial infectious spondylitis, Mycobacterium tuberculosis and S. aureus were the two major causative pathogens. MRSA caused more anterior operations and thoracic infections, while MSSA caused more posterior infections and lumbar infections. Differences between six S. aureus isolates from infectious spondylitis were characterized. MLST and staphylococcal cassette chromosome mec (SCCmec) analysis identified MSSA ST959 and ST30 isolates, MRSA ST239/SCCmec IIIA isolates 2 and 3, ST59/SCCmec IIIA-like isolate 6, and ST30/SCCmec IV isolate 5. While all of the isolates were resistant to penicillin and ampicillin, the MRSA isolates were more resistant than the MSSA isolates. Carbapenem-resistant MRSA ST239/SCCmec IIIA and ST59/SCCmec IIIA-like isolates of the agr1 type were also resistant to clindamycin and erythromycin. Leukocidin genes (pvl or lukED) and hemolysin genes (hla, hld and hlg) were present in all of the isolates. All six isolates caused more necrosis than apoptosis in the human alveolar basal epithelial cell line A549;however, ST59/SCCmec IIIA-like isolate 6, ST30/ SCCmec IV isolate 5 with pvl genes, and MSSA ST30 isolates with tst caused greater than 40% cell death after the 4-h incubation. Regardless of the MRSA isolate and its SCCmec type or the MSSA isolate, the infectious spondylitis-associated S. aureus isolates differed genetically, and the pvl and tst genes may be important genes for cell necrosis.

关键词： Infectious Spondylitis Staphylococcus aureus Virulence Factor MLST Necrosis Apoptosis

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有限相依随机序列的非贝叶斯变点最优监测

应用概率统计 2024年第2期40卷 277-286页

作者：韩东宗福季上海交通大学数学科学学院统计系上海200240 香港科技大学工业工程及决策分析学系中国香港香港科技大学(广州)数据科学与分析系广州510700

本文研究了有限相依样本序列的非贝叶斯变点检测问题.通过引入非负动态随机控制线,我们不仅构造并证明了两个最优控制图,而且还得到了比原定义更容易计算的Lorden测度和Pollak测度的最小值的表达式.

关键词：最优控制图非贝叶斯变点监测相依样本序列

Design of hadronic calorimeter for DarkSHINE experiment

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Nuclear Science and Techniques 2024年第9期35卷 155-167页

作者： Zhen Wang Rui Yuan han-Qing Liu Jing Chen Xiang Chen Kim Siang Khaw Liang Li Shu Li Kun Liu Qi-Bin Liu Si-Yuan Song Tong Sun Xiao-Long Wang Yu-Feng Wang Hai-Jun yang Jun-Hua Zhang Yu-Lei Zhang Zhi-Yu Zhao Chun-Xiang Zhu Xu-Liang Zhu Yi-Fan Zhu tsung-Dao Lee Institute Shanghai Jiao Tong University1 Lisuo RoadShanghai 201210China Institute of Nuclear and Particle Physics School of Physics and Astronomy800 Dongchuan RoadShanghai 200240China Key Laboratory for Particle Astrophysics and Cosmology(MOE) Shanghai Key Laboratory for Particle Physics and Cosmology(SKLPPC)Shanghai Jiao Tong University800 Dongchuan RoadShanghai 200240China Key Laboratory of Nuclear Physics and Ion-beam Application(MOE) Fudan UniversityShanghai 200443China Institute of Modern Physics Fudan UniversityShanghai 200443China

The sensitivity of the dark photon search through invisible decay final states in low-background experiments relies sig-nificantly on the neutron and muon veto efficiencies,which depend on the amount of material used and the design of the detector *** paper presents the optimized design of the hadronic calorimeter(HCAL)used in the DarkSHINE experiment,which is studied using a GEANT4-based simulation *** geometry is optimized by comparing a traditional design with uniform absorbers to one that uses different thicknesses at different locations on the detector,which enhances the efficiency of vetoing low-energy neutrons at the sub-GeV *** overall size and total amount of material used in the HCAL are optimized to be lower,owing to the load and budget requirements,whereas the overall performance is studied to satisfy the physical objectives.

关键词： Hadronic calorimeter GEANT4 simulation Neutron background Scintillation detector Dark photon

Adaptable retinal ganglion cell function: assessing autoregulation of inner retina pathways

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Neural Regeneration Research 2020年第12期15卷 2237-2238页

作者： tsung-han Chou Vittorio Porciatti Bascom Palmer Eye Institute University of Miami Miller School of Medicine

Retinal ganglion cell(RGC)function in health and disease:RGCs are extremely high-maintenance neurons connecting the eye to the brain trough the optic *** order to produce and propagate action potentials along the unmyelinated RGC axons and support axonal transport of materials back and forth from the eye to the brain,RGC require large amounts of ***,RGCs are under considerable metabolic stress when healthy and become particularly vulnerable in disease,resulting in blindness(Morgan,2004).

关键词： assessing function connecting

Platelet-rich plasma enhances adipose-derived stem cell-mediated angiogenesis in a mouse ischemic hindlimb model

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World Journal of Stem Cells 2018年第12期10卷 212-227页

作者： Chia-Fang Chen han-tsung Liao Department of Plastic and Reconstructive Surgery Chang Gung Memorial Hospital Craniofacial Research Center Chang Gung Memorial Hospital College of Medicine Chang Gung University

AIM To evaluate the angiogenic effect of platelet-rich plasma(PRP)-preconditioned adipose-derived stem cells(ADSCs) both in vitro and in a mouse ischemic hindlimb *** ADSCs were divided based on culture medium: 2.5% PRP, 5% PRP, 7.5% PRP, and 10% PRP. Cell proliferation rate was analyzed using the MTS assay. The gene expression of CD31, vascular endothelial growth factor, hypoxia-inducible factors, and endothelial cell nitric oxide synthase was analyzed using reverse transcription polymerase chain reaction. Cell markers and structural changes were assessed through immunofluorescence staining and the tube formation assay. Subsequently, we studied the in vivo angiogenic capabilities of ADSCs by a mouse ischemic hindlimb *** The proliferation rate of ADSCs was higher in the 2.5%, 5%, and 7.5% PRP groups. The expression of hypoxia-inducible factor, CD31, vascular endothelial growth factor, and endothelial cell nitric oxide synthase in the 5% and 7.5% PRP groups increased. The 5%, 7.5%, and 10% PRP groups showed higher abilities to promote both CD31 and vascular endothelial growth factor production and tubular structure formation in ADSCs. According to laser Doppler perfusion scan, the perfusion ratios of ischemic limb to normal limb were significantly higher in 5% PRP, 7.5% PRP, and human umbilical vein endothelial cells groups compared with the negative control and fetal bovine serum(FBS) groups(0.88 ± 0.08, 0.85 ± 0.07 and 0.81 ± 0.06 for 5%, 7.5% PRP and human umbilical vein endothelial cells compared with 0.42 ± 0.17 and 0.54 ± 0.14 for the negative control and FBS, P < 0.01).CONCLUSION PRP-preconditioned ADSCs presented endothelial cell characteristics in vitro and significantly improved neovascularization in ischemic hindlimbs. The optimal angiogenic effect occurred in 5% PRP-and 7.5% PRPpreconditioned ADSCs.

关键词： Platelet-rich plasma Adipose-derived stem cells Mesenchymal stem cell Angiogenesis Endothelial differentiation Mouse ischemic hindlimb model

Analytical Result on the Supercurrent Through a Superconductor/Quantum-Dot/Superconductor Junction

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Communications in Theoretical Physics 2002年第7期38卷 103-106页

作者： LI Wei ZHU Yu LIN tsung-han State Key Laboratory for Mesoscopic Physics and Department of Physics Peking University Beijing 100871 China State Key Laboratory for Mesoscopic Physics and Department of Physics Peking University Beijing 100871 China State Key Laboratory for Mesoscopic Physics and Department of Physics Peking University Beijing 100871 China

We present an analytical result for the supercurrent across a superconductor/quantum-dot/superconductor junction. By converting the current integration into a special contour integral, we can express the current as a sum of the residues of poles. These poles are real and give a natural definition of the Andreev bound states. We also use the exact result to explain some features of the supercurrent transport behavior.

关键词： supercurrent, superconductor/quantum-dot/superconductor junction

Andreev Tunneling Through a Ferromagnet/Quantum-Dot/Superconductor System

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Communications in Theoretical Physics 2002年第5期38卷 629-633页

作者： RAO Hong-Hu ZHU Yu LIN tsung-han State Key Laboratory for Mesoscopic Physics and Department of Physics Peking University Beijing 100871 China State Key Laboratory for Mesoscopic Physics and Department of Physics Peking University Beijing 100871 China State Key Laboratory for Mesoscopic Physics and Department of Physics Peking University Beijing 100871 China

We study Andreev tunneling through a ferromagnet/quantum-dot (QD)/superconductor system. By usingnonequilibrum Green function method, the averaged occupation of electrons in QD and the Andreev tunneling currentare studied. Comparing to the norma-metal/quantum-dot/superconductor, the system shows significant changes: (i)The averaged occupations of spin-up and spin-down electrons are not equal. (ii) With the increase of the polarizationof ferromagnetic lead, the Andreev reflection current decreases. (iii) However, even the ferromagnetic lead reaches fullpolarization, the averaged occupation of spin-down electrons is not zero. The physics of these changes is discussed.

关键词： Andreev tunneling, ferromagnet/quantum-dot/superconductor system

Validation of a steel dual-core self-centering brace （DC-SCB） for seismic resistance： from brace member to one-story one-bay braced frame tests

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Frontiers of Structural and Civil Engineering 2016年第3期10卷 303-311页

作者： Chung-Che CHOU Ping-Ting CHUNG tsung-han WU Alexis Rafael Ovalle BEATO Department of Civil Engineering Taiwan University Taipei Taiwan China Director Center for Earthquake Engineering Research (CEER) Taiwan University Taipei Taiwan China

A steel dual-core self-centering brace （DC-SCB） is an innovative structural member that provides both energy dissipation and self-centering properties to structures, reducing maximum and residual drifts of structures in earthquakes. The axial deformation capacity of the DC-SCB is doubled by a parallel arrangement of two inner cores, one outer box and two sets of tensioning elements. This paper presents cyclic test results of a DC-SCB component and a full- scale one-story, one-bay steel frame with a DC-SCB. The DC-SCB that was near 8 m-long was tested to evaluate its cyclic behavior and durability. The DC-SCB performed well under a total of three increasing cyclic loading tests and 60 low- cycle fatigue loading tests without failure. The maximum axial load of the DC-SCB was near 1700 kN at an interstory drift of 2.5%. Moreover, a three-story dual-core self-centering braced frame （DC-SCBF） with a single-diagonal DC-SCB was designed and its first-story, one-bay DC-SCBF subassembly specimen was tested in multiple earthquake-type loadings. The one-story, one-bay subassembly frame specimen performed well up to an interstory drift of 2% with yielding at the column base and local buckling in the steel beam; no damage of the DC-SCB was found after all tests. The maximum residual drift of the DC-SCBF caused by beam local buckling was 0.5% in 2.0% drift cycles.

关键词： dual-core self-centering brace (DC-SCB) braced frame tests residual deformation

Connection between Mott physics and crystal structure in a series of transition metal binary compounds

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npj Computational Materials 2019年第1期5卷 893-898页

作者： Nicola Lanatà tsung-han Lee Yong-Xin Yao Vladan Stevanović Vladimir Dobrosavljević Department of Physics and Astronomy Aarhus University8000 Aarhus CDenmark Department of Physics and National High Magnetic Field Laboratory Florida State UniversityTallahasseeFL 32310USA Department of Physics and Astronomy and Center for Condensed Matter Theory Rutgers UniversityPiscatawayNJ 088548019USA Ames Laboratory-U.S.DOE and Department of Physics and Astronomy Iowa State UniversityAmesIA 50011USA Colorado School of Mines and National Renewable Energy Laboratory GoldenCO 80401USA

The choice that a solid system“makes”when adopting a crystal structure(stable or metastable)is ultimately governed by the interactions between electrons forming chemical *** we analyze six prototypical binary transition metal compounds and shed light on the connection between Mott physics and the behavior of the energy as a function of the spatial arrangement of the atoms in these ***,we find that the main qualitative features of this complex behavior in the Mott phase of these systems can be traced back to the fact that the strong d-electron correlations influence substantially the charge transfer mechanism,which,in turn,controls the electrostatic *** result advances our understanding of the influence of strong correlations on the crystal structure,opens a new avenue for extending structure prediction methodologies to strongly correlated materials,and paves the way for predicting and studying metastability and polymorphism in these systems.

关键词： structure crystal binary