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Muscle hematoma:A critically important complication of alcoholic liver cirrhosis

World Journal of Gastroenterology 2009年第35期15卷 4457-4460页

作者： Chiyo Sugiyama Akifumi Akai Noriyoshi Yamakita tsuneko ikeda Keigo Yasuda Department of Internal Medicine Matsunami General Hospital185-1 DendaiKasamatsu-choHashima-gunGifu 501-6062Japan Department of Pathology Matsunami General Hospital185-1 DendaiKasamatsu-choHashima-gunGifu 501-6062Japan

An iliopsoas hematoma can occur either spontaneously or secondary to trauma or bleeding tendency due to hemophilia and anticoagulant *** liver cirrhosis is commonly associated with coagulopathy, iliopsoas hematoma is very *** herein,present a case of bilateral iliopsoas hematoma in a patient with alcoholic cirrhosis,and review the literature on muscle hematoma associated with cirrhosis.A 56-year-old man with alcoholic cirrhosis was admitted in a state of shock with *** cause of anemia could not be detected,and the patient was treated conservatively. The site of bleeding was not detected with either gastroduodenal endoscopy or upper abdominal computed tomography,the latter of which did not include the iliopsoas *** died on the 10th day of admission and bilateral iliopsoas hematomas were found on *** iron stain was positive in the iliopsoas *** cases of muscle hematoma associated with cirrhosis,including the present case, were found in a review of the *** of these cases involved the rectus abdominis muscle,3 involved the iliopsoas muscle and 1 involved combined *** cirrhosis accounted for 75%of the *** case(12.5%)was associated with virus- related cirrhosis,and another with combined virus- and alcohol-related *** mortality rate was 75%despite early diagnosis and low risk scores for *** hematoma in patients with cirrhosis isclosely related to alcoholism,and the mortality rate of the condition is extremely *** conclusion,muscle hematoma should be recognized as an important complication of cirrhosis.

关键词：并发症酒精性化极血肿肌肉肝

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Natural history of inferior mesenteric arteriovenous malformation that led to ischemic colitis: A case report

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World Journal of Clinical Cases 2021年第2期9卷 396-402页

作者： Yushi Kimura Takeshi Hara Ryotaro Nagao Takayuki Nakanishi Junji Kawaguchi Atsushi Tagami tsuneko ikeda Hiroshi Araki Hisashi Tsurumi Department of Gastroenterology Matsunami General HospitalHashima-gun 501-6062Japan Department of Hematology Matsunami General HospitalHashima-gun 501-6062Japan Department of Pathology Matsunami General HospitalHashima-gun 501-6062Japan

BACKGROUND Ischemic colitis with inferior mesenteric arteriovenous malformation(AVM)is a rare *** a few reports have been published,no report has described the natural history of idiopathic mesenteric *** SUMMARY A 50-year-old male was admitted to our hospital due to abdominal pain that had persisted for 3 mo and bloody *** had no history of trauma or abdominal *** had undergone two colonoscopies 6 mo and 2 years ago,and they showed only a *** was diagnosed with ischemic colitis with inferior mesenteric AVM following contrast-enhanced abdominal computed tomography(CT)and underwent rectal low anterior *** has not had a recurrence of symptoms for 3 *** history showed that he had undergone non-enhanced abdominal CT 2,5,and 8 years ago when he had attacks of urinary ***,dilation of blood vessels around the rectosigmoid colon could have been detected 5 years ago,and these findings gradually became more *** This is the first report of the natural history of inferior mesenteric AVM.

关键词： Inferior mesenteric arteriovenous malformation Ischemic colitis Natural history Case report Arteriovenous malformation

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Granulocyte-colony stimulating factor-producing squamous cell carcinoma arising in ovarian mature cystic teratoma: A case report

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Open Journal of Obstetrics and Gynecology 2013年第9期3卷 686-689页

作者： Satoshi Ichigo Hiroshi Takagi Kazutoshi Matsunami Takayuki Murase tsuneko ikeda Atsushi Imai Departments of Obstetrics and Gynecology Matsunami General Hospital Gifu Japan Departments of Pathology Matsunami General Hospital Gifu Japan

Granulocyte-colony stimulating factor (G-CSF)-producing cancer has been reported to occur in various organs. It has an aggressive nature and shows resistance to conventional treatments, however, its clinical features are not well known because of the small number or reported cases. We report G-CSF-producing squamous cell carcinoma arising in malignant-transformed ovarian mature cystic teratoma. An 80-year-old woman underwent suboptimal surgical excision of stage IIIC ovarian cancer. Prior to the treatment, the patient presented severe granulocytosis and elevated serum G-CSF concentration. With the help of histopathological and immunohistochemical studies, we diagnosed this case to be a poorly differentiated squamous cell carcinoma developed in ovarian mature cystic teratoma, which highly expressed G-CSF. During radiation therapy, the patient died from rapid growth of residual tumor and peritoneal dissemination 2 months after surgery. This is the first case of G-CSF-producing squamous cell carcinoma arising in malignant-transformed ovarian mature cystic teratoma, and its prognosis was very poor.

关键词： G-CSF-Producing Cancer Malignant Transformation of Mature Cystic Teratoma Squamous Cell Carcinoma Ovarian Cancer

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Occurrence of myelodysplastic syndrome during paclitaxel- and carboplatin-based chemotherapy for recurrent ovarian cancer: Case report

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Open Journal of Obstetrics and Gynecology 2013年第2期3卷 232-234页

作者： Hiroshi Takagi Satoshi Ichigo Kazutoshi Matsunami Haruna Takagi tsuneko ikeda Takayuki Murase Atsushi Imai Department of Obstetrics and Gynecology Matsunami General Hospital Gifu Japan Department of Pathology Matsunami General Hospital Kasamatsu Gifu Japan

Platinum and taxane have significant activity as key drugs in current treatment of advanced ovarian cancer. While myelodysplastic syndrome (MDS) and acute leukemia are wellknown secondary disease after administration of chemotherapy, particularly with alkylating agents, they have only rarely been reported in the context of ovarian cancer treatment. In this case report a 59-year-old Japanese developed a MSD during ongoing second induction chemotherapy with carboplatin and paclitaxel for recurrent ovarian cancer. Her second induction began 9 months after completion of her first course of chemotherapy. Cytogenetic analyses showed typical chromosomal aberration. Although the finding of pancytopenia is also seen during chemotherapy without MSD/acute leukemia, bone marrow aspiration and biopsy should be considered to confirm the clinical suspicion of the lifethreatening disease when encountered persistent pancytopenia following carboplatin and paclitaxel-based chemotherapy in an ovarian cancer patient.

关键词： Chemotherapy-Related Myelodysplastic Syndrome Ovarian Cancer Platinum Taxane

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