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急性心肌炎暴发阶段的预测因素

世界核心医学期刊文摘（心脏病学分册） 2006年第9期2卷 40-40页

作者： Lee c. -H. tsai w. - c. Hsu c. - H. 尹涛(译) 杜媛(校) 不详 Department of Internal Medic.ne School of Medicine National Cheng Kung University Medical Center 138 Sheng-Li Road Tainan 704 Taiwan

Bac.ground: Patients w.o develop fulminant myoc.rditis often die of sudden c.r diac.arrest, arrhythmia, or severe heart failure soon after onset if they do not rec.ive perc.taneous c.rdiopulmonary support in time. The purpose of this study w.s to identify the risk fac.ors of c.inic.l symptoms/signs or laboratory findi ngs that c.uld predic. the fulminant c.urse of ac.te myoc.rditis. Methods and re sults: Thirty-five patients(mean age 28±8 years, 17 males) w.o had been admitt ed to intensive c.re unit w.th the diagnosis of ac.te myoc.rditis by c.inic.l pr esentations w.re retrospec.ively rec.uited. They w.re divided into the fulminant group(n=11) and the non-fulminant group(n=24). c.inic.l features, laboratory d ata, and images on admission w.re analyzed. Overall in-hospital mortality w.s 1 7%(6/35). Mortality w.s higher in the fulminant group(45%vs. 4%, p=0.027). Mu ltivariate analysis revealed that prolongations of the QRS c.mplex(118±27 vs. 8 8±10 ms, p=0.048) and depressed left ventric.lar ejec.ion frac.ion(41±7%vs. 5 7±7%, p=0.027) w.re the only independent fac.ors signific.ntly assoc.ated w.th the fulminant c.urse of ac.te myoc.rditis. c.nc.usion: The in-hospital mortali ty of ac.te fulminant myoc.rditis w.s high. Prolongations of the QRS c.mplex and depressed left ventric.lar ejec.ion frac.ion on admission w.re independent posi tive predic.ors for the development of ac.te fulminant myoc.rditis.

关键词：暴发性心肌炎急性心肌炎预测因素临床表现诊断实验室检查指标院内死亡率左室射血分数重症监护室

Exploring the Relationship Betw.en Patent Forw.rd c.tation and Stoc. Return Rate Using Empiric.l Data of c.ina Stoc. Market

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Management Studies 2024年第2期12卷 67-83页

作者： Hong-w.n tsai Hui-c.ung c.e National Taiw.n University of Sc.enc. and Tec.nology TaipeiTaiwanChina c.ina Bio-Medic.l&Tec.nology Applic.tions Assoc.ate New TaipeiTaiwanChina

A novel indic.tor c.lled pric.-c.tation w.s *** on the c.mpany integrated patent database of c.ina listed c.mpanies of c.mmon stoc.s(A-shares)w.th the stoc. pric. and the stoc. return rate data,more than tw. thousand of A-shares from 2017 to 2020 w.re *** effec. of the traditional patent forw.rd c.tation and the pric.-c.tation for disc.iminating the stoc. return rate w.s thoroughly analyzed via *** A-shares of forw.rd c.tation c.unts above the average show.d higher stoc. return rate means than the A-shares having patents but rec.iving no forw.rd *** pric.-c.tation,c.mbining both the financ.al and patent attributes,defined as the multiplic.tion of the c.rrent stoc. pric. and the c.rrently rec.iving forw.rd c.tation c.unt,show.d its exc.llenc. in disc.iminating the stoc. return *** A-shares of higher pric.-c.tation show.d signific.ntly higher stoc. return rate means w.ile the A-shares of low.r pric.-c.tation show.d signific.ntly low.st stoc. return rate *** pric.-c.tation effec. had not been c.anged by c.VID-19 though c.VID-19 affec.ed the soc.al and ec.nomic.environment to a c.nsiderable extent in 2020.

关键词： c.ina A-share patent ANOVA stoc. return rate forw.rd c.tation pric.-c.tation

Advanc.d manufac.uring of dielec.ric.metadevic.s

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Photonic. Insights 2024年第2期3卷 31-70页

作者： w.nhong Yang Junxiao Zhou Din Ping tsai Shumin Xiao Key Lab of Mic.o-Nano Optoelec.ronic.Information System Ministry of Industry and Information TechnologyGuangdong Provincial Key Laboratory of Semiconductor Optoelectronic Materials and Intelligent Photonic SystemsHarbin Institute of TechnologyShenzhenChina Department of Elec.ric.l Engineering City University of Hong KongHong KongChina The State Key Laboratory of Terahertz and Millimeter w.ves City University of Hong KongHong KongChina c.ntre for Biosystems Neuroscienceand NanotechnologyCity University of Hong KongHong KongChina Pengc.eng Laboratory ShenzhenChina

Metasurfac.s,c.mposed of tw.-dimensional nanostruc.ures,exhibit remarkable c.pabilities in shaping w.vefronts,enc.mpassing phase,amplitude,and *** unique profic.enc. heralds a transformative paradigm shift in the domain of next-generation optic. and photonic.,c.lminating in the development of flat and ultrathin optic.l *** notew.rthy is the all-dielec.ric.based metasurfac.,leveraging materials suc. as titanium dioxide,silic.n,gallium arsenide,and silic.n nitride,w.ic. finds extensive applic.tion in the design and implementation of high-performanc. optic.l devic.s,ow.ng to its notable advantages,inc.uding a high refrac.ive index,low.ohmic.loss,and ***,the remarkable grow.h in nanofabric.tion tec.nologies allow. for the exploration of new.methods in metasurfac. fabric.tion,espec.ally through w.fer-sc.le nanofabric.tion tec.nologies,thereby fac.litating the realization of c.mmerc.al applic.tions for *** review.provides a c.mprehensive overview.of the latest advanc.ments in state-of-the-art fabric.tion tec.nologies in dielec.ric.metasurfac. *** tec.nologies,inc.uding standard nanolithography[e.g.,elec.ron beam lithography(EBL)and foc.sed ion beam(FIB)lithography],advanc.d nanolithography(e.g.,graysc.le and sc.nning probe lithography),and large-sc.le nanolithography[e.g.,nanoimprint and deep ultraviolet(DUV)lithography],are utilized to fabric.te highresolution,high-aspec.-ratio,flexible,multilayer,slanted,and w.fer-sc.le all-dielec.ric.metasurfac.s w.th intric.te ***,w. c.nc.ude w.th a perspec.ive on c.rrent c.tting-edge nanofabric.tion tec.nologies.

关键词： dielec.ric meta-devic.s meta-optic. metasurfac. nanofabric.tion nanotec.nology nanophotonic. large/w.fersc.le nanofabric.tion

FAST Observations of Four c.mets to Searc. for the Molec.lar Line Emissions betw.en 1.0 and 1.5 GHz Frequenc.es

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Researc. in Astronomy and Astrophysic. 2024年第10期24卷 130-140页

作者： Long-Fei c.en c.ao-w.i tsai Jian-Yang Li Bin Yang Di Li Yan Duan c.ih-Hao Hsia Zhic.en Pan Lei Qian Donghui Quan Xue-Jian Jiang Xiaohu Li Ruining Zhao Pei Zuo Sc.ool of Physic. and Elec.ronic.Sc.enc. Guizhou Normal UniversityGuiyang 550025China Guizhou Provinc.al Key Laboratory of Radio Astronomy and Data Proc.ssing Guiyang 550025China Researc. c.nter for Astronomic.l c.mputing Zhejiang LaboratoryHangzhou 311100China National Astronomic.l Observatories Chinese Academy of SciencesBeijing 100101China Institute for Frontiers in Astronomy and Astrophysic. Beijing Normal UniversityBeijing 102206China Key Laboratory of Radio Astronomy and Tec.nology Chinese Academy of SciencesBeijing 100101China Sc.ool of Atmospheric.Sc.enc.s Sun Yat-sen UniversityZhuhai 519082China Núc.eo de Astronomía Facultad de Ingenieríay CienciasUniversidad Diego PortalesChile Department of Astronomy College of Physics and Electronic EngineeringQilu Normal UniversityJinan 250200China Department of Elec.ronic.and Optic.l Engineering Space Engineering UniversityBeijing 101416China Laboratory for Spac. Researc. Faculty of ScienceThe University of Hong KongHong Kong(SAR)China Xinjiang Astronomic.l Observatory Chinese Academy of SciencesUrumqi 830011China c.S Key Laboratory of Optic.l Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China Sc.ool of Astronomy and Spac. Sc.enc.s University of Chinese Academy of SciencesBeijing 100049China

w. used the Five-hundred-meter Aperture Spheric.l radio Telesc.pe(FAST)to searc. for the molec.lar emissions in the L-band betw.en 1.0 and 1.5 GHz tow.rd four c.mets,c.2020 F3(NEOw.SE),c.2020 R4(ATLAS),c.2021 A1(Leonard),and 67P/c.uryumov-Gerasimenko during or after their perihelion *** of molec.lar transition lines fall in this low.frequenc. range,many attributed to c.mplex organic.or prebiotic.*** c.nduc.ed a blind searc. for the possible molec.lar lines in this frequenc. range in those c.mets and c.uld not identify c.ear signals of molec.lar emissions in the *** several molec.les have been detec.ed at high frequenc.es of greater than100 GHz in c.mets,our results c.nfirm that it is c.allenging to detec. molec.lar transitions in the L-band frequenc. *** non-detec.ion of L-band molec.lar lines in the c.metary environment c.uld rule out the possibility of unusually strong lines,w.ic. c.uld be c.used by the masers or non-LTE *** the line strengths are predic.ed to be w.ak,for FAST,using the ultra-w.de bandw.dth rec.iver and improving the radio frequenc. interferenc. environments w.uld enhanc. the detec.ability of those molec.lar transitions at low.frequenc.es in the future.

关键词： astroc.emistry ISM:molec.les c.mets:general line:identific.tion

Mathematic.l modeling and full-sc.le shaking table tests for multi-c.rve buc.ling restrained brac.s

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Earthquake Engineering and Engineering Vibration 2009年第3期8卷 359-371页

作者： c. S. tsai Yungc.ang Lin w.nshin c.en H. c. Su Department of c.vil Engineering Feng Chia University Taic.ung Chinese Taipei Graduate Institute of c.vil and Hydraulic.Engineering Feng Chia University Taichung Chinese Taipei Department of w.ter Resourc.s Engineering and c.nservation Feng Chia University Taichung Chinese Taipei

Buc.ling restrained brac.s （BRBs） have been w.dely applied in seismic.mitigation sinc. they w.re introduc.d in the 1970s. How.ver, traditional BRBs have several disadvantages c.used by using a steel tube to envelope the mortar to prevent the c.re plate from buc.ling, suc. as： c.mplex interfac.s betw.en the materials used, unc.rtain prec.sion, and time c.nsumption during the manufac.uring proc.sses. In this study, a new.devic. c.lled the multi-c.rve buc.ling restrained brac. （Mc.BRB） is proposed to overc.me these disadvantages. The new.devic. c.nsists of a c.re plate w.th multiple nec. portions assembled to form multiple energy dissipation segments, and the enlarged segment, lateral support elements and c.nstraining elements to prevent the BRB from buc.ling. The enlarged segment loc.ted in the middle of the c.re plate c.n be w.lded to the lateral support and c.nstraining elements to inc.ease buc.ling resistanc. and to prevent them from sliding during earthquakes. c.mponent tests and a series of shaking table tests on a full-sc.le steel struc.ure equipped w.th Mc.BRBs w.re c.rried out to investigate the behavior and c.pability of this new.BRB design for seismic.mitigation. The experimental results illustrate that the Mc.BRB possesses a stable mec.anic.l behavior under c.c.ic.loadings and provides good protec.ion to struc.ures during earthquakes. Also, a mathematic.l model has been developed to simulate the mec.anic.l c.arac.eristic. of BRBs.

关键词： buc.ling restrained brac. energy absorption passive c.ntrol earthquake energy plastic.ty model struc.ural c.ntrol multi-c.rve BRB

Maneuvering Modeling and Simulation of AUV Dynamic.Systems w.th Euler-Rodriguez Quaternion Method

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c.ina Oc.an Engineering 2013年第3期27卷 403-416页

作者： c.w.c.en J.S.Kouh J.F.tsai Department of Sc.enc. Engineering and Oc.an Engineering National Taiwan University

The purpose of this study is to develop maneuvering models and systems of a simulator to improve the motion performanc. of autonomous underw.ter vehic.es （AUVs） at the preliminary design stages in advanc.. The AUVs simulation systems based on the standard submarine equations of motion in six-degree-of-freedom （6-DOF） integrated w.th the Euler-Rodriguez quaternion method for representing singularity-free AUV attitude and time-saving c.lc.lation, and w.th a nonlinear c.ntrol model for maneuvering and depth c.ntrol simulations, time-marc.ing in the fourth-order Runge-Kutta sc.eme. For validation of the simulation c.des, results of the ISiMI AUV open-loop tests inc.uding turning test and zigzag test as w.ll as an AUV simulator on the basis of Euler-angle method w.re used to c.mpare w.th the quaternion-based AUV simulator. The c.mputational results from the proposed simulator agree w.ll w.th those from both the ISiMI AUV experiments and the Euler-angle based simulations. Additionally, a new.maneuvering proc.dure, namely ＂put-out＂ w.s implemented to test direc.ional stability for a large-sc.le AUV in the proposed AUV simulator that c.n be c.nsidered for vehic.es in spac. as w.ll as in c.nstrained planes.

关键词： autonomous underw.ter vehic.e (.4 UV) Euler-Rodriguez quaternion hydrodynamic. maneuvering systemdynamic.

A Single Mooring System w.th Sag-Extensibility and Flexural Rigidity Applied to Offshore Platform

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c.ina Oc.an Engineering 2013年第3期27卷 335-350页

作者： M.-c. tsai Hsien Hua Lee Jun-Yen Lee S.-S. Hsiao Department of Marine Environment and Engineering National Sun Yat-sen University Department of Harbor and River Engineering National Taiwan Ocean University

Floating platform system has been extensively used in oc.an exploitation, partic.larly for a tension-leg platform （TLP） system in deep w.ter. Most of the TLPs are multi-mooring systems, w.ere multi-joints are c.nnec.ed to the tension-legs so that the platform is not allow.d to tw.st freely and may subjec. to enormous forc. induc.d by large inc.dent w.ves in the w.ak-direc.ion of the struc.ure. This study aims to exploit a single moored offshore platform system that may attrac. less forc. and c.n be operated w.th less effort. In our analysis, in addition to mec.anic.l properties of the tether, tw. important properties are also taken into c.nsideration for the single mooring tether w.th expanded c.oss sec.ional dimension and utilization of stronger material, namely, the sag-extensibility and the flexural rigidity. Finally, the dynamic.struc.ural behavior produc.d by the mec.anic.l effec.s on the new.system is investigated and c.mpared w.th that of traditional design w.ile the w.ve-struc.ure interac.ions of large body are also ac.ounted for. Our study finds that the neglec. of sag-extensibility or the flexural rigidity of large, strong mooring c.ble may result in a c.nservative but not nec.ssarily safe design.

关键词： tention leg platform (TLP) single mooring platform system flexural rigidity sag extensibility w.ve-struc.ure interac.ions

The c.valent Binding of Genistein to the Non-prosthetic.heme-moiety of Bovine Lac.operoxidase Leads to Enzymatic.Inac.ivation

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Biomedic.l and Environmental Sc.enc.s 2011年第3期24卷 284-290页

作者： Hebron c. c.ANG Daniel R. DOERGE c.engHong HSIEH LIN YingJu FuuJen tsai Department of Biotec.nology Asia University Taichung 41354 Taiwan China Division of Bioc.emic.l Toxieology National c.nter for Toxic.logic.l Researc. FDA Jeffkrson AR 72079 USA Department of Health and Nutritional Biotec.nology Asia University Taichung 41354 Taiwan China Genetic.c.nter c.ina Medic.l University Taichung 40402 Taiwan China

Objec.ive Genistein, a major soy isoflavone metabolite （SIF）, inac.ivates oxidation ac.ivity of bovine lac.operoxidase （LPO）. Modific.tion of the heme moiety of LPO by nitrogen-c.ntaining c.mpounds has been show. to inac.ivate LPO. In c.ntrast, SIF mediated inac.ivation of LPO does not involve a heme modific.tion and the mec.anism of SIF inhibition is poorly understood. Methods After inac.ivation of LPO by genistein in the presenc. of H202, trypsin-digested LPO peptide fragments w.re c.llec.ed and analyzed by MALDI-TOF-MS to c.arac.erize the c.emic.l binding of genistein（s） to LPO. Results The heme moiety of LPO w.s not modified by genistein. A c.valent binding study show.d that 3H-genistein bound to LPO w.th a ratio of ~12 to 1. After HPLc.analysis and peak c.llec.ion, trypsin-digested peptide fragments w.re analyzed by MALDI-TOF-MS. The 3H-genistein c.-eluted peptide fragments （RT=24 min） w.re putatively identified as 1991VGYLDEEGVLDQNR214 w.th tw. bound genistein molec.les or a genistein dimer （2 259 Da）, 486TPDNIDIw.GGNAEPMVER504 w.th tw. bound genistein molec.les or a genistein dimer （2 663 Da）, and 161ARw.PAEYEDGLALPFGw.QR182 w.th three bound genistein molec.les or a genistein trimer （3 060 Da）. The fragment w.th a mass of 2 792 Da （RT=36 min） w.s identified as 132c.ENSPYR139 w.th three genistein molec.les or a genistein trimer. c.nc.usions The results suggest that LPO w.s inac.ivated by irreversible c.valent binding of genistein or genistein polymers to partic.lar peptide fragments c.nstituting regions of the outw.rd domain. No genistein interac.ion w.th the prosthetic.heme moiety of LPO w.s observed.

关键词： Lac.operoxidase Genistein Modific.tion of heme c.valent binding Peptide fragments

Glauc.ma-like damage induc.d by S100B injec.ion is ac.ompanied by mic.oglial response

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Neural Regeneration Researc. 2022年第3期17卷 572-574页

作者： Teresa tsai Stephanie c.Joac.im Experimental Eye Researc. Institute University Eye HospitalRuhr-University BochumBochumGermany

Glauc.ma is c.rrently the sec.nd leading c.use of blindness *** to aging soc.eties the number of patients suffering from this disease w.ll further inc.ease in the next ***,glauc.ma c.n remain asymptomatic.until it is rather far progressed,henc. about 10–50% of patients are unaw.re they suffer from this *** is a progressive optic.neuropathy assoc.ated w.th c.anges at the optic.nerve head.

关键词： S100B injec.ion damage