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肝胆外科杂志 2021年第6期29卷 479-480页

作者： Beugniez C sauvanet A sulpice L Gaujoux s Turrini O truant s schwarz L Piessen G Regimbeau JM Muscari F Adham M Pattou F schneider L Clement G Delpero JR Pruvot FR Mehdi EA 崔笑(摘译) 薛鸿(摘译) 耿小平(审校) French-ACHBT Working Group 不详

虽然近年来胰腺手术技术取得了长足进步,但胰腺术后发生死亡的事件依然仍有发生.本研究分析了法国多个高流量胰腺外科中心2015年1月至2018年12月期间接受胰腺切除术90天内死亡的原因.共9个中心纳入研究患者3195例,术后90天内死亡140例,3... 详细信息

虽然近年来胰腺手术技术取得了长足进步,但胰腺术后发生死亡的事件依然仍有发生.本研究分析了法国多个高流量胰腺外科中心2015年1月至2018年12月期间接受胰腺切除术90天内死亡的原因.共9个中心纳入研究患者3195例,术后90天内死亡140例,39例患者因故排除,有效分析101例.30%的死亡是术前评估或术后管理不善导致,约10%是不恰当的术中决策所致.高龄、联合动脉切除,尤其是计划外手术切除,是死亡相关危险因素.

关键词：胰腺手术胰腺外科胰腺切除术术前评估死亡原因分析计划外相关危险因素术后管理

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Enlarged and uncommon indications for ALPPs-where do we stand?

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Hepatobiliary surgery and Nutrition 2022年第5期11卷 743-745页

作者： stéphanie truant Department of Digestive surgery and Transplantation CHU LilleUniv.LilleLilleFrance CANTHER Laboratory“Cancer Heterogeneity Plasticity and Resistance to Therapies”UMR-S1277Team“MucinsCancer and Drug Resistance”LilleFrance

Associating liver partition and portal vein ligation for staged hepatectomy(ALPPs)has been introduced in 2012 as an innovative surgical option that offers patients curative resection in otherwise nonresectable *** the high morbi-mortality rates and poor oncologic outcome in the early experience,indications of ALPPs have been restricted to young patients with colorectal liver metastases(CRLM)following the first report on the international ALPPs registry(1).ALPPs further gained in safety after the first International ALPPs Meeting held in 2015(2)in Hamburg,which prompted surgeons to better patient selection by chemotherapy(3),technical refinements toward less invasive ALPPs procedures(4),and better inter-stage decision making(5).

关键词： ALPPs indications mortality

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Kinetics of remnant liver volume and function after a major hepatectomy

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Hepatobiliary surgery and Nutrition 2023年第6期12卷 975-977页

作者： stéphanie truant Mehdi El Amrani François-RenéPruvot Department of Digestive surgery and Transplantation Hôpital HuriezCHU LilleUniv.LilleLilleFrance CANTHER Laboratory“Cancer Heterogeneity Plasticity and Resistance to Therapies”UMR-S1277Team“MucinsCancer and Drug Resistance”LilleFrance

Liver regeneration after a major hepatectomy(MH)is crucial for the patient postoperative recovery,with the first postoperative month(1M)being a critical period for the liver regeneration *** risk of post hepatectomy liver failure(PHLF),which is the leading cause of death,is usually anticipated in the preoperative period by the measurement of the future remnant liver volume(RLV)via computed tomography(CT)with volumetry.

关键词： Liver regeneration remnant liver volume(RLV) remnant liver function major hepatectomy(MH)

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Prognostication algorithm for non-cirrhotic non-B non-C hepatocellular carcinoma-a multicenter study under the aegis of the French Association of Hepato-Biliary surgery and liver Transplantation

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Hepatobiliary surgery and Nutrition 2023年第2期12卷 192-204,I0002-I0004页

作者： Charlotte Maulat stéphanie truant Christian Hobeika Louise Barbier Astrid Herrero Alexandre Doussot Johan Gagnière Édouard Girard Hadrien Tranchart Jean-Marc Regimbeau David Fuks François Cauchy Mathieu Prodeau Antoine Notte Cyprien Toubert Ephrem salamé Mehdi El Amrani sandrine Andrieu Fabrice Muscari Jason shourick Bertrand suc Department of Digestive surgery Hepatobiliary and Pancreatic Surgery and Liver Transplantation UnitToulouse University HospitalToulouseFrance Department of Digestive surgery and Transplantation Claude-HuriezHospitalCHRU LilleLilleFrance CANTHER laboratory“Cancer Heterogeneity Plasticity and Resistance to Therapies”Inserm UMR-S1277 Teams“MucinsCancer and Drug Resistance”LilleFrance Department of Hepato-bilio-pancreatic surgery and Liver Transplantation Beaujon HospitalAPHPClichyFrance Department of Digestive surgery and Liver Transplantation Trousseau HospitalTours University HospitalToursFrance Department of Digestive surgery and Liver Transplantation Saint Eloi HospitalMontpellier University HospitalMontpellierFrance Department of Digestive surgery and Liver Transplantation Besançon University HospitalBesançonFrance Department of Digestive and Hepatobiliary surgery University Hospital of Clermont-FerrandClermont-FerrandFrance U1071 Inserm/UniversitéClermont-Auvergne Clermont-FerrandFrance Department of Digestive surgery and Emergency CHU Grenoble-AlpesGrenobleFrance Department of Mini-invasive surgery Antoine Béclère HospitalAPHPClamartFrance Department of Digestive surgery Amiens Picardie University Hospital and Picardie Jules Verne UniversityAmiensFrance Department of Digestive surgery Institut Mutualiste MontsourisParisFrance Department of Epidemiology Toulouse University HospitalToulouseFrance

Background:Liver resection and local ablation are the only curative treatment for non-cirrhotic hepatocellular carcinoma(HCC).Few data exist concerning the prognosis of patients resected for non-cirrhotic *** objectives of this study were to determine the prognostic factors of recurrence-free survival(RFs)and overall survival(Os)and to develop a prognostication algorithm for non-cirrhotic ***:French multicenter retrospective study including HCC patients with non-cirrhotic liver without underlying viral hepatitis:F0,F1 or F2 ***:A total of 467 patients were included in 11 centers from 2010 to ***-cirrhotic liver had a fibrosis score of F0(n=237,50.7%),F1(n=127,27.2%)or F2(n=103,22.1%).Os and RFs at 5 years were 59.2%and 34.5%,*** multivariate analysis,microvascular invasion and HCC differentiation were prognostic factors of Os and RFs and the number and size were prognostic factors of RFs(Pstratification based on RFs provided an algorithm based on size(P=0.013)and number(Pst nodule≤10 cm(n=271,Group 1);2 HCC with a nodule>10 cm(n=176,Group 2);>2 HCC regardless of size Conclusions:We developed a prognostication algorithm based on the number(≤or>2)and size(≤or>10 cm),which could be used as a treatment decision support concerning the need for perioperative *** case of bifocal HCC,surgery should not be a contraindication.

关键词： Hepatocellular carcinoma(HCC) non-cirrhotic liver prognostic factors recurrence-free survival(RFs) prognostication algorithm

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