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Prevalence, risk factors, and BRAF mutation of colorectal sessile serrated lesions among Vietnamese patients

World Journal of Clinical Oncology 2024年第2期15卷 290-301页

作者： Nhu Thi Hanh Vu Huy Minh Le Diem Thi-Ngoc Vo Hoang Anh Vu Nhan Quang Le Dung Dang Quy Ho Duc trong Quach Department of Internal Medicine University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam GI Endoscopy Department University Medical Center at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Department of Histology-Embryology and Pathology University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Center for Molecular Biomedicine University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Department of Endoscopy Cho Ray HospitalHo Chi Minh 700000Viet Nam

BACKGROUND Sessile serrated lesions(SSLs)are considered precancerous colorectal lesions that should be detected and removed to prevent colorectal *** studies in Vietnam mainly investigated the adenoma pathway,with limited data on the serrated *** To evaluate the prevalence,risk factors,and BRAF mutations of SSLs in the Vietnamese *** This is a cross-sectional study conducted on patients with lower gastrointestinal symptoms who underwent colonoscopy at a tertiary hospital in *** were diagnosed on histopathology according to the 2019 World Health Organi-zation *** mutation analysis was performed using the Sanger DNA sequencing *** multivariate logistic regression model was used to determine SSL-associated *** There were 2489 patients,with a mean age of 52.1±13.1 and a female-to-male ratio of 1:*** prevalence of SSLs was 4.2%[95%confidence interval(CI):3.5-5.1].In the multivariate analysis,factors significantly associated with SSLs were age≥40[odds ratio(OR):3.303;95%CI:1.607-6.790],male sex(OR:2.032;95%CI:1.204-3.429),diabetes mellitus(OR:2.721;95%CI:1.551-4.772),and hypertension(OR:1.650,95%CI:1.045-2.605).The rate of BRAF mutations in SSLs was 35.5%.CONCLUSION The prevalence of SSLs was 4.2%.BRAF mutations were present in one-third of *** risk factors for SSLs included age≥40,male sex,diabetes mellitus,and hypertension.

关键词： Colorectal cancer Sessile serrated lesion BRAF mutation Risk factors Diabetes mellitus Hypertension

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走滑断层或逆断层活动的地震:对余震活动的影响及大余震发生的预报

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地震地质译丛 1994年第2期16卷 33-39页

作者： P.Hoang-trong D.Rouland 郭跃宏刘艺林

大地震后总是跟随着余震。但大余震本身可能增加破坏性,其发生决不是系统的。利用美国国家地震信息中心13年期间的震源参数数据组和震源测定结果,及由一个宽频带地震台记录所推算的相应震级M_s值,我们根据主震的断层活动机制,表示大震... 详细信息

大地震后总是跟随着余震。但大余震本身可能增加破坏性,其发生决不是系统的。利用美国国家地震信息中心13年期间的震源参数数据组和震源测定结果,及由一个宽频带地震台记录所推算的相应震级M_s值,我们根据主震的断层活动机制,表示大震序列的特性,即逆断层(1),正断层(2)和走滑断层(3)三种机制,并且对它们进行了比较。我们指出,线性回归曲线的斜率logM_o=f(M_s),在机制(1)比机制(3)的大。结果,应力降在机制(1)比机制(3)的低。这种结果意味着:(a)主震和最大余震之间的震级差在(1)比(3)的小。(b)余震序列持续时间在(1)比(3)的长。文中以世界各地的地震及加利福尼亚一些地震为例作了说明。这些进一步证实,通常余震活动对逆断层活动的地震比起对走滑断层活动的地震更为重要。对于正断层活动(2)我们不作任何推论。

关键词：余震地震预报走滑断层逆断层

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Multinational survey on the preferred approach to management of Barrett’s esophagus in the Asia-Pacific region

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World Journal of Gastrointestinal Oncology 2021年第4期13卷 279-294页

作者： Guan Sen Kew Alex Yu Sen Soh Yeong Yeh Lee Takuji Gotoda Yan-Qing Li Yan Zhang Yiong Huak Chan Kewin Tien Ho Siah Daniel Tong Simon Ying Kit Law Andrew Ruszkiewicz Ping-Huei Tseng Yi-Chia Lee Chi-Yang Chang Duc trong Quach Chika Kusano Shobna Bhatia Justin Che-Yuen Wu Rajvinder Singh Prateek Sharma Khek-Yu Ho Department of Gastroenterology and Hepatology University Medicine ClusterNational University Health SystemSingapore 119228Singapore Department of Gastroenterology and Hepatology National University HospitalNational University Health SystemSingapore 119074Singapore School of Medical Sciences Universiti Sains MalaysiaPenang 11800Malaysia Division of Gastroenterology and Hepatology Department of MedicineNihon University School of MedicineTokyo 173-8610Japan Department of Gastroenterology Laboratory of Translational GastroenterologyQilu Hospital of Shandong UniversityJinan 250012Shandong ProvinceChina Yong Loo Lin School of Medicine National University of SingaporeSingapore 119228Singapore Department of Surgery The University of Hong KongHong Kong PokfulamHong KongChina Department of Pathology SA PathologyAdelaide 5112Australia Department of Internal Medicine National Taiwan University HospitalTaipei 100Taiwan Department of Internal Medicine Fu Jen Catholic University HospitalTaipei 24352Taiwan Department of Internal Medicine University of Medicine and Pharmacy at Hochiminh CityVietnamHochiminh 70000Viet Nam Department of Gastroenterology Seth GS Medical College and King Edward Memorial HospitalMumbai 400012India Department of Medicine and Therapeutics The Chinese University of Hong KongHong KongChina Department of Gastroenterology Lyell McEwin HospitalUniversity of AdelaideAdelaide 64128Australia Department of Gastroenterology and Hepatology Kansas City VA Medical CenterKansas CityKS 64128United States Department of Medicine National University HospitalSingapore 119074Singapore

BACKGROUND Major societies provide differing guidance on management of Barrett’s esophagus(BE),making standardization *** To evaluate the preferred diagnosis and management practices of BE among Asian *** Endoscopists from across Asia were invited to participate in an online questionnaire comprising eleven questions regarding diagnosis,surveillance and management of *** Five hundred sixty-nine of 1016(56.0%)respondents completed the survey,with most respondents from Japan(n=310,54.5%)and China(n=129,22.7%).Overall,the preferred endoscopic landmark of the esophagogastric junction was squamocolumnar junction(42.0%).Distal palisade vessels was preferred in Japan(59.0%vs 10.0%,P<0.001)while outside Japan,squamo-columnar junction was preferred(59.5%vs 27.4%,P<0.001).Only 16.3%of respondents used Prague C and M criteria all the *** was never used by 46.1%of Japanese,whereas 84.2%outside Japan,endoscopists used it to varying extents(P<0.001).Most Asian endoscopists(70.8%)would survey long-segment BE without dysplasia every two *** to Seattle protocol was poor with only 6.3%always performing it.73.2%of Japanese never did it,compared to 19.3%outside Japan(P<0.001).The most preferred(74.0%)treatment of non-dysplastic BE was proton pump inhibitor only when the patient was symptomatic or had *** BE with low-grade dysplasia,6-monthly surveillance was preferred in 61.9%within Japan vs 47.9%outside Japan(P<0.001).CONCLUSION Diagnosis and management of BE varied within Asia,with stark contrast between Japan and outside *** Asian endoscopists chose squamo-columnar junction to be the landmark for esophagogastric junction,which is *** also did not consistently use Prague criteria,and Seattle *** of standardization,education and research are possible reasons.

关键词： Barrett's esophagus Survey Asia-Pacific Asian Barrett's consortium Prague criteria Seattle protocol

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屏蔽壳结构高Q值混合谐振器集成带通滤波器

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微波学报 2016年第6期32卷 16-18,34页

作者：黎重孝朱晓维盖川东南大学信息科学与工程学院毫米波国家重点实验室南京210096

提出了一种基于混合谐振器的新型二阶带通滤波器,该混合谐振器由微带线和一个短路的铜柱线组成,这可以利用射频收发系统的结构件空间,并方便与平面微带电路集成,以提高滤波器的品质因数,它的无载Q值为455,高于传统的微带谐振器。而且,... 详细信息

提出了一种基于混合谐振器的新型二阶带通滤波器,该混合谐振器由微带线和一个短路的铜柱线组成,这可以利用射频收发系统的结构件空间,并方便与平面微带电路集成,以提高滤波器的品质因数,它的无载Q值为455,高于传统的微带谐振器。而且,通过源负载耦合和混合电磁耦合的方法,在通带两边分别有一个可调的传输零点,提高滤波器带外抑制特性。实验结果表明,测试结果与仿真数据吻合良好。

关键词：混合谐振器无载Q值传输零点带通滤波器

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Quality of life in esophageal cancer patients Impacts of Treatments on the Quality of Life among Esophageal Squamous Cell Carcinoma Patients

Quality of life in esophageal cancer patients Impacts of Tre...

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第九届中国肿瘤学术大会暨第十五届海峡两岸肿瘤学术大会

作者： Shwn-Huey Shieh Chih-Yi Chen Vivian Chia-Rong Hsieh ChinHung Chang Pin-Ru Chen trong-Neng Wu Wen-Miin Liang Shih-Chun Pan Department of Health Services Administration “China Medical University” Department of Nursing “China Medical University and Hospital” Institute of Medicine Department of SurgeryChung Shan Medical UniversityChung Shan Medical University Hospital Department of Physical Medicine and Rehabilitation and the Beuhler Center on Aging Health & SocietyNorthwestern University Feinberg School of Medicine Division of Thoracic Surgery “China Medical University and Hospital” Department of Healthcare Administration Asia University Division of Environmental Health and Occupational Medicine “National Health Research Institutes” Graduate Institute of Biostatistics “China Medical University” Institute of Occupational Medicine and Industrial Hygiene Taiwan University

Background This study aims to investigate the effects of different treatments on the quality of life of esophageal squamous cell carcinoma patients in *** From a medical center in central Taiwan,patients who had been diagnosed with esophageal squamous cell carcinoma from February 2007 and March 2011 are *** the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30(EORTC QLQ-C30)and the Quality of Life Questionnaire Oesophageal 18(QLQOES18),quality of life scores for 105 esophageal squamous cell carcinoma patients are obtained and *** analysis is performed on the quality of life scores after stratification by cancer *** Among early-stage esophageal squamous cell carcinoma patients,those received only surgery(S-only)performed better in physical and social functioning compared with patients who underwent surgery and concurrent chemoradiotherapy(S+CCRT)(β=9.0,p=0.03;β=12.1,p=0.04,respectively).For those that received only concurrent chemoradiotherapy(CCRT-only),they performed worse in role and emotional functioning relative to S+CCRT patients(β=-17.2,p=0.02;β=-15.7,p=0.05,respectively).Among late-stage patients,CCRTonly treatment gave insignificantly better global health status and functional scale scores and less severe symptoms compared to the S+CCRT *** Better functional scores and less aggravated symptoms are observed in early-stage esophageal squamous cell carcinoma patients who received surgery-only treatment relative to those that underwent both surgery and *** late-stage esophageal cancer patients,CCRT-only may be preferred over multiple treatments to avoid surgical risk and is generally less aggressive.

关键词： EORTC QLQ-C30 EORTC QLQ-OES18 esophageal cancer squamous cell carcinoma treatment quality of life

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山体滑坡对可持续性发展的影响(英文)

山体滑坡对可持续性发展的影响(英文)

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北京论坛（2008）文明的和谐与共同繁荣——文明的普遍价值和发展趋向

作者： Chu Van Ngoi Ta trong Thang Luong Thi Thu Hoai Hanoi University of Science VNUVietnam

Vietnam is characterized by 2/3 mountain area,intensively separated and narrow *** on natural conditions,the territory is divided into 3 parts:the North,the Central and the *** part has different characteristic of climate,rainy regime and hydrological *** Vietnam,the storm season and rainy season happen in a same time that increase dangerous level of natural *** recent years,human activities,especially opening new roads,improving and straightening old roads,have destroyed stability of slopes,leading to landslide in the whole country,seriously along highways and roads in the rain and *** addition,landslide is also caused by rock ***’s why landslide becomes one of the disasters in ***,these measures are not answered for natural condition in Vietnam. So,in order to solve this problem Vietnam needs to apply modern geo-technical measures for safety of transportation.

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越南东京湾红河断裂系统

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海洋地质 2010年第2期26卷 1-13页

作者： C．Rangin M. Klein D. Roques X. Le Pichon Le Van trong 孙桂华（译） Ddpartement de Gdotectonique CNRS URA 1759 T26 - 0 Unit＇ ersit - Pierre et Marie Curie 4 Place Jussieu 75252 Paris Paris Cedex 05 France Total la Dffense Paris France Ecole Normale Supdrieure Paris France Petrocietnam Hanoi VietNam 广州海洋地质调查局海洋区域地质调查所

本文利用经过钻井资料校准的地震剖面研究了东京湾海防海域的红河断裂系统。该断裂系统在VinhMirth断层西南部表现为30km宽的狭长的左行走滑带，其运动时间为30Ma-5．5Ma，走滑位移不会超过几十公里，没有识别出5．5Ma之后的右行走滑运... 详细信息

本文利用经过钻井资料校准的地震剖面研究了东京湾海防海域的红河断裂系统。该断裂系统在VinhMirth断层西南部表现为30km宽的狭长的左行走滑带，其运动时间为30Ma-5．5Ma，走滑位移不会超过几十公里，没有识别出5．5Ma之后的右行走滑运动。30Ma之前存在一个100km宽的伸展带，这次伸展作用可能与左行运动有关。30Ma之前，断裂系统在VinhMinh断层东北方向的分叉很可能刻E部湾的裂谷作用所吸收。15．5Ma的不整合将该区张扭体系与晚期的压扭体系分开，这个不整合的年代与南海海底扩张停止的时间是一致的。

关键词：断裂系统东京湾红河越南运动时间伸展作用地震剖面钻井资料

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不平顺谱对列车轨道系统动力性能影响的对比分析

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铁道标准设计 2015年第7期59卷 15-19页

作者：张重王刘学毅苏成光赵林西南交通大学高速铁路线路工程教育部重点实验室

轨道不平顺是影响高速列车-轨道系统动力响应的主要因素之一,为了对比分析不平顺谱对列车轨道系统的影响,运用轮轨系统动力学的基本原理,建立列车-无砟轨道-路基系统垂向耦合动力模型,计算分析3种不平顺谱下车辆和轨道系统的动力响应。... 详细信息

轨道不平顺是影响高速列车-轨道系统动力响应的主要因素之一,为了对比分析不平顺谱对列车轨道系统的影响,运用轮轨系统动力学的基本原理,建立列车-无砟轨道-路基系统垂向耦合动力模型,计算分析3种不平顺谱下车辆和轨道系统的动力响应。结果表明:不同轨道谱作用下车辆与轨道系统动力响应具有较大的差异,美国轨道谱的影响最大;武广客运专线轨道谱的影响最小,但对轨道系统的影响与德国谱相近。建议对于具体实际问题,应选用合理轨道谱:既有的武广客运专线不平顺谱是在运营初期测得,适用于开通初期的高速铁路线路,对于已经运营数年的武广客运专线,应进行不平顺谱的复测,才能准确反映实际情况。

关键词：轨道不平顺动力响应轨道系统高速列车

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