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Chinese Chemical Letters 2016年第5期27卷 731-737页

作者： Keyur D. Bhatt Disha J. Vyas bharat A. Makwana Savan M. Darjee Vinod K. Jain Hemangini Shah Department of Chemistry C.U. Shah University Wadhwan 363030 India Department of Chemistry School of Sciences Gujarat University Ahmedabad 380009 India

A simple and quick method for the synthesis of water dispersible stable silver nanoparticles has been developed. Calix[4]pyrrole octahydrazide （CPOH）, has been successfully used as a reducing as well as stabilizing agent for the synthesis of silver nanoparticles. CPOH-AgNps have been duly characterized by SPR, PSA, TEM and EDX-ray. The ability of CPOH-AgNps as selective and sensitive sensor for various ions （Pb（Ⅱ）, Cd（II）, Mn（Ⅱ）, Fe（Ⅲ）, Ni（Ⅱ）, Zn（Ⅱ）, Hg（Ⅱ）, Co（Ⅱ）, Cu（Ⅱ）） by colorimetry and spectrofluorimetry has been explored. CPOH-AgNps were found to be selective only for Hg（Ⅱ） ions. Nanomolar concentration of Hg（Ⅱ） ions can also be determined by spectrofluorimetry by increase in fluorescence intensity. Linear range of detection of Hg（Ⅱ） ions in water was found to be from 1nmol/L to mol/L. The method has been successfully applied for determination of Hg（Ⅱ） ions in ground water and industrial effluent waste water samples.

关键词： Calixpyrrole Silver nanoparticles Fluorescence study Colorimetric sensor Water samplesHg(Ⅱ) ions

The Role of Library and Information Science Education in the Development of Community Health Information Services for People Living with HIV/AIDS: Perspectives of Directors and Managers of Public Libraries

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World Journal of AIDS 2011年第3期1卷 78-87页

作者： bharat Mehra Adrienne Dessel 不详

This article identifies the role of library and information science (LIS) education in the development of community health information services for people living with HIV/AIDS (PLWHA). Preliminary findings are presented from semi- structured qualitative interviews that were conducted with eleven directors and managers of local branches in the Knox County Public Library (KCPL) System that is located in the East Tennessee region in the United States. Select feedback reported by research participants is summarized in the article about strategies in LIS education that can help local public librarians and others in their efforts to become more responsive information providers to PLWHA. Research findings help better understand the issues and concerns regarding the development of digital and non-digital health information services for PLWHA in local public library institutions.

关键词： People Living with HIV/AIDS PLWHA Public Library Directors and Managers Community Health Information Services

Photocatalytic reduction of organic pollutant under visible light by green route synthesized gold nanoparticles

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Journal of Environmental Sciences 2017年第5期29卷 236-246页

作者： bharat C.Choudhary Debajyoti Paul Tarun Gupta Sandesh R.Tetgure Vaman J.Garole Amulrao U.Borse Dipak J.Garole School of Chemical Sciences North Maharashtra University Jalgaon 425001 Maharashtra India Centre for Environmental Science & Engineering Indian Institute of Technology Kanpur Kanpur 208016 Uttar Pradesh India Department of Earth Sciences Indian Institute of Technology Kanpur Kanpur 208016 Uttar Pradesh India Enoironmental Enoineering and Manaoement Department of Civil Engineering Indian Institute of Technology Kanpur Kanpur 208016 Uttar Pradesh India Directorate of Geology and Mining Government of Maharashtra Nagpur 440010 Maharashtra India

We report a rapid method of green chemistry approach for synthesis of gold nanoparticles（AuNPs）using Lagerstroemia speciosa leaf extract（LSE）. L. speciosa plant extract is known for its effective treatment of diabetes and kidney related problems. The green synthesis of Au NPs was complete within 30 min at 25°C. The same could also be achieved within 2 min at a higher reaction temperature（80°C）. Both UV–visible spectroscopy and transmission electron microscopy results suggest that the morphology and size distribution of Au NPs are dependent on the pH of gold solution,gold concentration,volume of LSE,and reaction time and temperature. Comparison between Fourier transform infrared spectroscopy（FT-IR）spectra of LSE and the synthesized Au NPs indicate an active role of polyphenolic functional groups（from gallotannins,lagerstroemin,and corosolic acid）in the green synthesis and capping of Au NPs. The green route synthesized Au NPs show strong photocatalytic activity in the reduction of dyes viz.,methylene blue,methyl orange,bromophenol blue and bromocresol green,and 4-nitrophenol under visible light in the presence of Na BH4. The non-toxic and cost effective LSE mediated Au NPs synthesis proposed in this study is extremely rapid compared to the other reported methods that require hours to days for complete synthesis of Au NPs using various plant extracts. Strong and stable photocatalytic behavior makes Au NPs attractive in environmental applications,particularly in the reduction of organic pollutants in wastewater.

关键词： Green synthesis Gold nanoparticles Lagerstroemia speciosa Photocatalyst Dyes Nitroaromatic compound

Hyperglycemia in COVID-19 infection without diabetes mellitus:Association with inflammatory markers

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World Journal of Clinical Cases 2023年第6期11卷 1287-1298页

作者： Harinivaas Shanmugavel Geetha Garima Singh Abinesh Sekar Maya Gogtay Yuvaraj Singh George MAbraham Nitin trivedi Department of Internal Medicine Saint Vincent HospitalWorcesterMA 01608United States Department of Hospice and Palliative Medicine University of Texas HealthSan AntonioTX 78229United States Department of Internal Medicine University of Massachusetts Chan Medical SchoolWorcesterMA 01655United States

BACKGROUND New onset hyperglycemia is common in patients with severe coronavirus disease 2019(COVID-19)*** storm due to COVID-19 infection is an essential etiology for new-onset hyperglycemia,but factors like direct severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)-induced pancreaticβ-cell failure have also been postulated to play a *** We plan to investigate further the mechanisms underlying SARS-CoV-2 infection-induced hyperglycemia,particularly the rationale of the cytokine-induced hyperglycemia hypothesis,by evaluating the association between inflammatory markers and new onset hyperglycemia in non-diabetic patients with COVID-19 *** We conducted a retrospective case-control study on adults without diabetes mellitus hospitalized for COVID-19 *** serum levels of glucose and inflammatory markers at presentation before initiation of corticosteroid were *** was defined as glucose levels≥140 mg/dL.C-Reactive protein(CRP)≥100 mg/L,ferritin≥530 ng/mL,lactate dehydrogenase(LDH)≥590 U/L,and D-dimer≥0.5 mg/L were considered *** used theχ2 test for categorical variables and the Mann-Whitney U test for continuous variables and calculated the logistic regression for *** Of the 520 patients screened,248 met the inclusion *** demographics were equally distributed between patients with hyperglycemia and those who were *** inflammatory markers in patients with or without new-onset hyperglycemia were elevated as follows:CRP(58.1%vs 65.6%,P=0.29),ferritin(48.4%vs 34.9%,P=0.14),D-dimer(37.1%vs 37.1%,P=0.76)and LDH(19.4%vs 11.8%,P=0.02).Logistic regression analysis showed LDH odds ratio(OR)=1.623(P=0.256).We observed significantly higher mortality(24.2%vs 9.1%,P=0.001;OR=2.528,P=0.024)and length of stay(8.89 vs 6.69,P=0.026)in patients with *** Our study showed no association between CRP,ferritin,LDH,D-dimer levels,and new-onset hyperg

关键词： COVID-19 Inflammatory markers Hyperglycemia C-reactive protein Mortality Severity Mechanisms Diabetes mellitus

Application of Omori’s Decay Law to the 2001 Bhuj Aftershock Sequence for Kachchh Region of Western India

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Open Journal of Earthquake Research 2015年第3期4卷 94-101页

作者： Parul C. trivedi India Meteorological Department Ahmedabad India

In the present study, the temporal behavior of 2001 Bhuj aftershock sequence in Kachchh region of western peninsular India is studied by the modified Omori law. The Omori law parameters p, c and K are determined with the standard errors by the maximum likelihood estimates using ZMAP algorithm in MatLab environment. The entire aftershock sequence is analyzed by diving it into three separate series with respect to time to weigh up the bigger earthquake of magnitude M 5.7 occurring on March 7, 2006 at Gedi fault. This study helps to understand the cumulative effect of the aftershocks generated by this bigger earthquake of the mainshock sequence. The results of this analysis are discussed with other studies of the different earthquake sequence for the different parts of the world and suggest that all the three series of Bhuj aftershock sequence follow the Omori relation. Values of parameter p vary significantly from series 1 to series 3, i.e., p-value varies significantly with time. Similarly, other two Omori law parameters K and c are also found to change significantly with time. These parameters are useful to describe temporal behavior of aftershocks and to forecast aftershock activity in time domain. Aftershock decay rate provides insight into stress release processes after the mainshock, thus helping to understand the heterogeneity of the fault zone properties and evaluate time-dependent seismic hazard analysis over the region.

关键词： Omori Decay Law Aftershock Activity p-Value Bhuj Earthquake

Diabetes more than retinopathy,it’s effect on the anterior segment of eye

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World Journal of Clinical Cases 2023年第16期11卷 3736-3749页

作者： Arvind Kumar Morya Prasanna Venkatesh Ramesh Kirandeep Kaur bharat Gurnani Aarti Heda Karan Bhatia Aprajita Sinha Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Glaucoma and Research Mahathma Eye Hospital Private LimitedTennurTrichy 620001Tamil NaduIndia Pediatric Ophthalmology and Strabismus Sadguru Netra ChikitsalayaSadguru Seva Sangh TrustJanaki-KundChitrakoot 485334Madhya PradeshIndia Cornea and Refractive Services Sadguru Netra ChikitsalayaSadguru Seva Sangh TrustJanaki-KundChitrakoot 485334Madhya PradeshIndia Department of Ophthalmology National Institute of OphthalmologyPune 411000MaharashtraIndia Department of Ophthalmology Manaktala Eye and Maternity HomeMeerut 250001Uttar PradeshIndia Department of Ophthalmology Worcestershire Acute HospitalWorcestershire 01601United Kingdom

Diabetes mellitus(DM)is one of the chronic metabolic noncommunicable diseases that has attained worldwide *** threatens healthy life around the globe,with mild-to-severe secondary complications and leads to significant illness including nephropathy,neuropathy,retinopathy,and macrovascular abnormalities including peripheral vasculopathy,and ischaemic heart *** into diabetic retinopathy(DR),which affects one-third of persons with diabetes,has made considerable strides in recent *** addition,it can lead to several anterior segment complications such as glaucoma,cataract,cornea,conjunctiva,lacrimal glands and other ocular surface *** DM also caused gradual damage to corneal nerves and epithelial cells,which raises the likelihood of anterior segment diseases including corneal ulcers,dry eye disease,and chronic epithelial *** DR and other associated ocular complications are well-known,the complexity of its aetiology and diagnosis makes therapeutic intervention *** glycaemic control,early detection and regular screening,and meticulous management is the key to halting the progression of the *** this review manuscript,we aim to provide an in-depth understanding of the broad spectrum of diabetic complications in the anterior segment of the ocular tissues and illustrate the progression of diabetes and its pathophysiology,epidemiology,and prospective therapeutic *** first such review article will highlight the role of diagnosing and treating patients with a plethora of anterior segment diseases associated with diabetes,which are often neglected.

关键词： Diabetes Ocular surface Cataract Glaucoma Lens Uvea

Biochar improves soil properties and corn productivity under drought conditions in South Korea

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Biochar 2023年第1期5卷 1148-1158页

作者： Jae-Hyuk Park Jin-Ju Yun Seong-Heon Kim Jong-Hwan Park bharat Sharma Acharya Ju-Sik Cho Se-Won Kang Department of Agricultural Chemistry Sunchon National UniversitySuncheon 57922Republic of Korea Division of Soil and Fertilizer National Institute of Agricultural SciencesRDAWanju 55365Republic of Korea Department of Life Resources Industry Dong-A UniversityBusan 49315Republic of Korea Rodale Institute Southeast Organic CenterChattahoochee HillsGA 30268USA Department of Agricultural Life Sciences Sunchon National UniversitySuncheon 57922Republic of Korea

Biochar has been shown to improve soil properties and plant productivity in soils with inherently low ***,little has been reported for upland corns under dry and wet precipitation *** study investigates the effect of biochar addition on a range of soil physicochemical,biological,and hydrological properties,and corn growth and productivity under agrometeorological drought and wet ***,experiments were laid out in a randomized complete block design with three replications at two sites during 2017 and 2018 in South *** included(i)CN:control(ii)IF:inorganic fertilizer(N-P-K)at 145-30-60 kg ha^(−1);(iii)BS:barley straw at 5 t ha^(−1);(iv)CWBC:corn waste biochar at 5 t ha^(−1);(v)CWBC+IF:corn waste biochar+inorganic fertilizer;(vi)CWBC+BS:corn waste biochar+barley *** year 2017 was relatively dry,whereas the year 2018 was *** drought conditions in the year 2017,biochar facilitated soil water ***,higher precipitation in 2018 increased the quantity and distribution of soil water and nutrients in the top 15 *** reduced soil bulk density,and increased porosity,cation exchange capacity and total organic carbon in both years but increased total bacterial counts during the dry year *** population was generally higher under wet ***,more soil CO_(2) was emitted in the wet year than in the dry *** further indicated that biochar can enhance corn biomass and grain yield regardless of precipitation *** grain index was,however,affected by rainfall and was significantly different across treatments in the year 2018 *** biomass,grain yield,and grain index were highest in CWBC+IF treatment and lowest under CN ***,biochar addition appeared to improve soil quality and soil conditioning effects in the drought and wet years,ameliorating soil and plant ***,biochar can improve water and nutrients storage,availability,and uptake,and

关键词： Biochar Drought Precipitation Soil CO_(2)

Neurocysticercosis (NCC) vs Central Nervous System (CNS) Tuberculoma in Children—Dilemma over Clinico-Radiological Diagnosis?

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Open Journal of Pediatrics 2016年第3期6卷 245-251页

作者： bharat-Bhushan Sharma Shashi Sharma Department of Radio-Diagnosis SGT Medical College Gurgaon India Department of Pediatrics SGT Medical College Gurgaon India

Background: Neurocysticercosis (NCC) and central nervous system (CNS) tuberculomas often overlap in clinical presentation and imaging. Though the aetio-pathology entirely differs in both the scenarios but there is great confusion in their clinico-radiological evaluation as the findings and appearances are similar in many ways. The stress should be laid out over the salient features of each entity in the background of their presentation. The study was conducted to highlight the differentiation of the clinico-radiological findings in both the entities. Material and Methods: Ten patients between 5 - 15 years (mean age 10.4 years) with complaints of headache and with or without seizures had undergone MRI alone or with CT examinations. Basic sequences of T1W, T2W, T2W FLAIR and T1W contrast studies were carried out in all the cases. CT was carried out in only three cases and contrast was given in two cases. Results: Eight patients were having ring enhancing lesions in post contrast studies in MRI and two had only cystic lesions ranging from 1 - 3 cm in diameter. Conclusion: Seven cases having tuberculomas were confirmed by both the modalities with one case inconclusive. Two cases were diagnosed as neurocysticercosis as per the results. The reasonable achievable target was the goal to differentiate between NCC and tuberculomas in the brain and it was achieved. Contrast MRI and spectroscopy brought out many findings for the distinct features in many cases.

关键词： Neurocysticercosis Tuberculomas Seizures CT MRI

Identification of Potential Landslide Susceptible Area in the Lesser Himalayan Terrain of Nepal

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Journal of Geoscience and Environment Protection 2019年第11期7卷 24-38页

作者： Kismat Pokhrel bharat Prasad Bhandari Goldengate International College Tribhuvan University Kathmandu Nepal Central Department of Environment Science Tribhuvan University Kathmandu Nepal

Landslide susceptibility mapping is a very important tool to identify potential landslide-prone areas. In this work, weight of evidence method is applied to obtain landslide susceptibility assessment. Weight of evidence model is commonly applied in the landslide study as it is widely acceptable and easy to use. The objective of this paper is to prepare the landslide susceptibility map of Lung Khola catchment, Pyuthan District of Nepal. Altogether, 84 landslides were identified after landslide inventory. The thematic layers of all causative factors and existing landslides are prepared in Arc GISsoftware. Mainly, Digital Elevation Model (DEM) based causative factors and field data were used to prepare the data layers of the causative factors. In this research, 8 intrinsic factors were used for the landslide assessment. South East and East facing aspects, slope >60 degrees, elevation ranges 1300 - 1700 m, phylitic rocks and agricultural land followed by forest are the major contributors of landslide hazard in the study area. The weight of evidence model was validated by using area under curve method. The success rate curve showed the accuracy of 73.16%. It can be concluded that weight of evidence model is suitable model for landslide susceptibility analysis and the area is highly susceptible to landslide occurrence.

关键词： Weight of Evidence Landslide Modeling Bivariate Method DEM

Differential miRNA expression profiling of highly pathogenic avian influenza virus H5N1 infected chicken lungs reveals critical microRNAs,biological pathways and genes involved in the molecular pathogenesis

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Virologica Sinica 2022年第3期37卷 465-468页

作者： Anamika Mishra Muhasin Asaf Amod Kumar Diwakar Dattatreya Kulkarni Richa Sood Sandeep Bhatia bharat Bhushan Ashwin Ashok Raut Pathogenomics Laboratory ICAR-National Institute of High Security Animal DiseasesOIE referral laboratory for Avian InfluenzaBhopal 462021India ICAR-National Institute of High Security Animal Diseases OIE referral lab for Avian InfluenzaBhopal 462021India Division of Animal Genetics ICAR-Indian Veterinary Research InstituteBareilly 243122India

Dear Editor,Avian influenza is a highly contagious viral infection affecting the respiratory ***(miRNAs)are small,regulatory,endogenous,non-coding RNAs of~22 nt that regulate the gene expression of the target mRNAs by cleavage or translational *** are connected with the host response during avian influenza virus(AIV)infection(Wang et al.,2009,2012).In this study.

关键词： influenza endogenous pathogenesis