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语数外学习(高中版高三年级) 2007年第10期 44-46页

作者： travis myers

Most people would agree that watching movies is one of their favorite free-time activities. We often think of movies as fun entertainment, but

关键词： Using Films as a Learning Tool

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Using Films as a Learning Tool

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语数外学习(高中版高一年级) 2007年第11期 44-46页

作者： travis myers

Most people would agree that watching movies is one of their favorite free-time activities. We often think of movies as fun entertainment, but have you ever considered that movies can also be used to help us

关键词： Using Films as a Learning Tool

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Perioperative treatment options in resectable pancreatic cancer-how to improve long-term survival

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World Journal of Gastrointestinal Oncology 2016年第3期8卷 248-257页

作者： Marianne Sinn Marcus Bahra Timm Denecke Sue travis Uwe Pelzer Hanno Riess Department of Medical Oncology and Haematology Charité-Universitatsmedizin Berlin Department of General Visceral and Transplantation SurgeryCharité-Universitatsmedizin Berlin Institute of Radiology Charité-Universitatsmedizin Berlin

Surgery remains the only chance of cure for pancreatic cancer, but only 15%-25% of patients present with resectable disease at the time of primary diagnosis. Important goals in clinical research must therefore be to allow early detection with suitable diagnostic procedures, to further broaden operation techniques and to determine the most effective perioperative treatment of either chemotherapy and/or radiation therapy. More extensive operations involving extended pancreatectomy, portal vein resection and pancreatic resection in resectable pancreatic cancer with limited liver metastasis, performed in specialized centers seem to be the surgical procedures with a possible impact on survival. After many years of stagnation in pharmacological clinical research on advanced pancreatic ductal adenocarcinomas(PDAC)- since the approval of gemcitabine in 1997- more effective cytotoxic substances(nab-paclitaxel) and combinations(FOLFIRINOX) are now available for perioperative treatment. Additionally, therapies with a broader mechanism of action are emerging(stroma depletion, immunotherapy, antiinflammation), raising hopes for more effective adjuvant and neoadjuvant treatment concepts, especially in the context of "borderline resectability". Only multidisciplinary approaches including radiology, surgery, medical and radiation oncology as the backbones of the treatment of potentially resectable PDAC may be able to further improve the rate of cure in the future.

关键词： Pancreatic cancer Perioperative treatment Perioperative radiology Chemotherapy

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