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Metastatic(Advanced)Prostate Cancer Resistant to Castration:The Time before Resistance Development and Therapeutic Measures Undertaken in Cote d’Ivoire

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Journal of Cancer Therapy 2018年第12期9卷 955-961页

作者： Kouassi Kouame Konan Yvon Toure Moctar Seka Evrard Narcisse Oumou Kimso traore Kadjatou Odo Bitti Adde traore asmaho danielle Kagambega Arsene Gaetan Adoubi Innocent Oncology Department of the Treichville University Hospital AbidjanCote d’Ivoire

Objective: Contribute to improving care for prostate cancer patients in Cote d’Ivoire by identifying the average time before the development of the hormone-resistance and inherent therapeutic strategies. Patients and Method: It was a retro and prospective study over three years performed at the University Teaching Hospital of Treichville in Abidjan. 84 patients with metastatic prostate adenocarcinoma and resistant to hormone therapy were involved in the study. The analysis of clinical records enabled us to integrate different parameters in our study. Results: Our patients were relatively young (an average age of 61 years) and most of them belonged to the middle socio-economic class (50%). The resistance occurred within an average period of 9 months. The mixing of Docetaxel and Prednisone chemotherapy was the most used method of treatment (70% of cases). However, few patients (9.5%) received Abiraterone Acetate. Digestive and hematologic toxicities were noticed but they could be controlled by inherent treatment or disappear spontaneously. After nine months of treatment, 54.24% of patients who received specific treatment were alive, but high rates of mortality were observed as for patients who were only treated symptomatically. Conclusion: The relatively short average time before the development of hormone-resistance shows the aggressiveness of prostate adenocarcinoma from black Africans. The main therapeutic standard in our context remains Taxane-based chemotherapy with a good and fair tolerance.

关键词： Cancer Prostate Occurrence Time Resistance

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Oncosexology in côte d’Ivoire:Attitudes and Practices of Physicians Involved in the Management of Breast and Prostate Cancer

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Psycho-Oncologie 2024年第4期18卷 359-365页

作者： KouaméKonan Yvon Kouassi Bitti Adde Odo Yenahaban Lazare Toure Ouowene Prisca Marina Sougue Petiori Gningayou Laurenceépouse Kamara Touré N’Guessan Manlan Prosper Mebiala Fleur Audrey Sessegnon Marie Sandrine Koffi Akissi Marie Barbara Yvonne Nogbou Sherif traore asmaho Akissi danielle Andree traore-Kouassi Moctar Toure Department of Medicine and Medical Specialties UFR Medical SciencesFélix Houphouët Boigny UniversityYamoussoukro01 BP V166 Abidjan 01Côte d’Ivoire Service De Cancerologie Du Chu De Treichville Treichville01 BP V03 Abidjan 01Côte d’Ivoire

Objective:To evaluate the attitudes and practices of oncosexology in the management of breast and prostate cancer in Côte d’***:A cross-sectional,multicenter,descriptive and analytical survey carried out over 02 months from 1 November to 31 December 2022,among doctors involved in the management of breast and prostate cancer in Côte d’***:78 physicians on 114 participated in the study,with a participation rate of 79.5%.Only one doctor discussed the sexual risks associated with cancer with all his patients and 7.7%of doctors said they never broached questions of sexuality with their *** approach to sexuality was strongly associated with occupation(p=0.002).A request for oncosexological care was initiated by the patient and the partner respectively in 3.8%and 25.6%of *** 5.1%of physicians claimed to have received training in *** 92.3%of cases,doctors would like to have training on this ***:On the questions relating to sexuality,Physicians are not addressing sexuality with their patients diagnosed with breast or prostate *** lack of training in this area appears to be the main reason for this lack of communication and onco-sexological care.

关键词： Oncosexology oncosexuality breast prostate

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Non-Small Cell Lung Cancer:Therapeutic and Evolutionary Aspects in Cote d’Ivoire

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Advances in Lung Cancer 2018年第1期7卷 1-8页

作者： TouréMoctar Kouassi KouaméKonan Yvon Séka Evrard Narcisse TraoréKadjatou Traoréasmaho danielle Odo Bitti Addé Oumou Kimso Kagambega Arsène Gaetan Adoubi Innocent Oncology Department of the Treichville University Hospital AbidjanCote d’Ivoire

Non-small cell lung cancer (NSCLC) is a heterogeneous group of malignancies including squamous cell carcinoma, adenocarcinoma, bronchioloalveolar carcinoma and large cell carcinoma. They are known to be of poor prognosis, despite a better understanding of bronchial oncogenesis. This descriptive retrospective study carried out over three years (January 2013 to December 31st, 2016) at the Oncology Department of the Treichville University Hospital in Abidjan was aimed to assess the efficacy of new treatments for NSCLC in Cote d’Ivoire and to specify their benefit in terms of quality of life, comfort and overall survival. This 77 patients study, found that NSCLC, the most frequent of which is squamous cell carcinoma, occurs in relatively young subjects, smokers (91%) diagnosed at a locally advanced or metastatic stage (89%). Cisplatin base multi-drug chemotherapy was mostly used (71%). Combined all treatments, there was a significant clinical gain. However, no complete response was observed. Hematological and digestive toxicities were seen in more than 30% of cases. Overall survival was of 9 months on average. This study is an advocate to optimize primary prevention policies for a cancer with poor prognosis despite the development of new treatments such as target therapies.

关键词： Non-Small Cell Lung Cancer Treatment Evolution

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