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Surveillance of dengue and chikungunya infection in Dong Thap,Vietnam:A 13-month study

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Asian Pacific Journal of Tropical Medicine 2016年第1期9卷 36-40页

作者： Pham Thi Kim Lien Laurence Briant Truong Ba Tang Bui Minh trang Laurent Gavotte Emmanuel Comillot Vu Trong Duoc tran nhu duong Roger Frutos Phan Thi Nga National Institute of Hygiene and Epidemiology University of Montpellier Department of Biology Dong Thap General Hospital Cirad TA-A17/GCampus International de Raillarguet

Objective:To establish a surveillance in Dong Thap,at the border with Cambodia by assessing the presence of DHNV serotypes and CHIKV among patients hospitalized at Dong Thap general ***:Cross-sectional descriptive analysis was conducted on a cohort of 131 patients hospitalized with acute fever and symptoms compatible with dengue or *** study was conducted from January 2012 to February *** full clinical picture was established as well as serological and molecular *** analysis was sequentially performed on blood samples collected on admission and an average of seven days after *** detection of IgM antibody to DENV was performed by IgM capture ELTSA and the detection of DENV and CHIKV RNA was done by reverse-transcription multiplex ***:101 patients out of 131(77%) were confirmed with *** four dengue serotypes were detected with a predominance of DENV2 and *** chikungunya infection was detected although reported in neighboring Cambodia.A differential efficiency of serological dengue detection was *** was 29%upon admission and 53%after seven days on the same patients.30 patients out of 131(23%) were negative with both DENV and ***:Dengue is at risk of being underestimated and chikungunya is not systematically *** in detection and surveillance procedures are therefore discussed to increase efficiency of dengue detection and continue the monitoring the emergence of CHIKV in Dong Thap province and in Vietnam.

关键词： Dengue Chikungunya Arbovirus Dong ThapVietnam

Photocatalytic degradation of antibiotic sulfamethizole by visible light activated perovskite LaZnO_(3)

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Journal of Environmental Sciences 2024年第10期144卷 212-224页

作者： Bui The Huy XCuong Nguyen Vu Khac Hoang Bui Nguyen Ngoc Tri Iqra Rabani nhu Hoa Thi tran Quang Viet Ly Hai Bang Truong Major of Biomedical Engineering Division of Smart HealthcareCollege of Information Technology and ConvergencePukyong National UniversityBusan 48513Korea Center for Advanced Chemistry Institute of Research and DevelopmentDuy Tan UniversityDa Nang 550000Viet Nam Faculty of Environmental and Chemical Engineering Duy Tan UniversityDa Nang 550000Viet Nam Department of Environment and Energy Sejong UniversitySeoul 05006Korea Lab of Computational Chemistry and Modelling Department of ChemistryFaculty of Natural SciencesQuy Nhon UniversityQuy NhonViet Nam Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Korea Faculty of Materials Science and Technology University of ScienceHo Chi Minh City 700000Viet Nam Vietnam National University Ho Chi Minh City 700000Viet Nam Department of Environmental Engineering Seoul National University of Science and TechnologySeoul 01811Korea Optical Materials Research Group Science and Technology Advanced InstituteVan Lang UniversityHo Chi Minh CityViet Nam Faculty of Applied Technology School of TechnologyVan Lang UniversityHo Chi Minh CityViet Nam

In thiswork,the perovskite LaZnO_(3) was synthesized via sol-gel method and applied for photocatalytic treatment of sulfamethizole(SMZ)antibiotics under visible light *** was almost completely degraded(99.2%±0.3%)within 4 hr by photocatalyst LaZnO3 at the optimal dosage of 1.1 g/L,with amineralization proportion of 58.7%±0.4%.The efficient performance of LaZnO_(3) can be attributed to itswide-range light absorption and the appropriate energy band edge levels,which facilitate the formation of active agents such as·O_(2)^(−),h^(+),and·*** integration of RP-HPLC/Q-TOF-MS and DFT-based computational techniques revealed three degradation pathways of SMZ,which were initiated by the deamination reaction at the aniline ring,the breakdown of the sulfonamidemoieties,and a process known as Smile-type rearrangement and SO2 *** toxicity of SMZ and the intermediateswere analyzed by quantitative structure activity relationship(QSAR),indicating the effectiveness of LaZnO_(3)-based photocatalysis in preventing secondary pollution of the intermediates to the ecosystem during the degradation *** visible-light-activated photocatalyst LaZnO_(3) exhibited efficient performance in the occurrence of inorganic anions and maintained high durability across multiple recycling tests,making it a promising candidate for practical antibiotic treatment.

关键词： Perovskite Antibiotics Photocatalysis Density functional theory Toxicity

Push forward LC-MS-based therapeutic drug monitoring and pharmacometabolomics for anti-tuberculosis precision dosing and comprehensive clinical management

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Journal of Pharmaceutical Analysis 2024年第1期14卷 16-38页

作者： Nguyen Quang Thu Nguyen tran Nam Tien Nguyen Thi Hai Yen Thuc-Huy duong Nguyen Phuoc Long Huy Truong Nguyen Department of Pharmacology and PharmacoGenomics Research Center Inje University College of MedicineBusan47392Republic of Korea Department of Chemistry University of EducationHo Chi Minh City700000Viet Nam Faculty of Pharmacy Ton Duc Thang UniversityHo Chi Minh City700000Viet Nam

The spread of tuberculosis(TB),especially multidrug-resistant TB and extensively drug-resistant TB,has strongly motivated the research and development of new anti-TB *** strategies to facilitate drug combinations,including pharmacokinetics-guided dose optimization and toxicology studies of first-and second-line anti-TB drugs have also been introduced and *** chromatography-mass spectrometry(LC-MS)has arguably become the gold standard in the analysis of both endo-and exo-genous *** technique has been applied successfully not only for therapeutic drug monitoring(TDM)but also for pharmacometabolomics *** improves the effectiveness of treatment,reduces adverse drug reactions,and the likelihood of drug resistance development in TB patients by determining dosage regimens that produce concentrations within the therapeutic target *** on TDM,the dose would be optimized individually to achieve favorable *** is essential in generating and validating hypotheses regarding the metabolism of anti-TB drugs,aiding in the discovery of potential biomarkers for TB diagnostics,treatment monitoring,and outcome *** article highlighted the current progresses in TDM of anti-TB drugs based on LC-MS bioassay in the last two ***,we discussed the advantages and disadvantages of this technique in practical *** pressing need for non-invasive sampling approaches and stability studies of anti-TB drugs was ***,we provided perspectives on the prospects of combining LC-MS-based TDM and pharmacometabolomics with other advanced strategies(pharmacometrics,drug and vaccine developments,machine learning/artificial intelligence,among others)to encapsulate in an all-inclusive approach to improve treatment outcomes of TB patients.

关键词： Tuberculosis Therapeutic drug monitoring LC-MS MIPD Pharmacometabolomics Precision medicine

An isogeometric approach to free vibration analysis of bi-directional functionally graded porous doubly-curved shallow microshells with variable length-scale parameters

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Frontiers of Structural and Civil Engineering 2023年第12期17卷 1871-1894页

作者： Khuat Duc duong Dao nhu MAI Phung Van MINH tran Van KE Faculty of Mechanical Engineering Hanoi University of IndustryHanoi 100000Vietnam Institute of Mechanics Vietnam Academy of Science and TechnologyHanoi 100000Vietnam Faculty of Mechanical Engineering Le Quy Don Technical UniversityHanoi 100000Vietnam

This study uses iso-geometric investigation,which is based on the non-uniform rational B-splines(NURBS)basis function,to investigate natural oscillation of bi-directional functionally graded porous(BFGP)doublycurved shallow microshells placed on Pasternak foundations with any boundary *** characteristics of the present material vary in both thickness and axial directions along the *** be more specific,a material length-scale coefficient of the microshell varies in both thickness and length directions as the material's mechanical *** is able to develop a differential equation system with varying coefficients that regulate the motion of BFGP double-curved shallow microshells by using Hamilton principle,Kirchhoff-Love hypothesis,and modified couple stress *** numerical findings are reported for thin microshells that are spherical,cylindrical,and hyperbolic paraboloidal,with a variety of planforms,including rectangles and *** validity and effectiveness of the established model are shown by comparing the numerical results given by the proposed formulations with previously published findings in many specific *** addition,influences of length scale parameters,power-law indexes,thickness-to-side ratio,and radius ratio on natural oscillation responses of BFGP microshells are investigated in detail.

关键词： Kirchhoff-Love's shell theory isogeometric analysis bi-directional functionally graded free vibration variable length-scale parameter

Numerical investigation of the influence of casting techniques on fiber orientation distribution in ECC

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Frontiers of Structural and Civil Engineering 2022年第11期16卷 1424-1435页

作者： Chung Nguyen VAN Hai tran THANH Thuc nhu NGUYEN Jianchun LI Faculty of Civil Engineering Ho Chi Minh City University of Technology and EducationHo Chi Minh 721400Vietnam School of Civil and Environmental Engineering University of Technology SydneySydneyNSW 2007Australia School of Civil Engineering Hue Industrial CollegeHue 49120Vietnam

Engineered cementitious composites(ECC),also known as bendable concrete,were developed based on engineering the interactions between fibers and cementitious *** orientation of fibers,in this regard,is one of the major factors influencing the ductile behavior of this *** this study,fiber orientation distributions in ECC beams influenced by different casting techniques are evaluated via numerical modeling of the casting *** casting directions and two casting positions of the funnel outlet with beam specimens are modeled using a particle-based smoothed particle hydrodynamics(SPH)*** this SPH approach,fresh mortar and fiber are discretized by separated mortar and fiber particles,which smoothly interact in the computational domain of *** movement of fiber particles is monitored during the casting ***,the fiber orientations at different sections of specimens are determined after the fresh ECC stops flowing in the *** simulation results show a significant impact of the casting direction on fiber orientation distributions along the longitudinal wall of beams,which eventually influence the flexural strength of *** addition,casting positions show negligible influences on the orientation distribution of fibers in the short ECC beam,except under the pouring position.

关键词： ECC fiber orientation distribution casting direction casting position

Development of a PARCS/Serpent model for neutronics analysis of the Dalat nuclear research reactor

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Nuclear Science and Techniques 2021年第2期32卷 32-44页

作者： Viet-Phu tran Kien-Cuong Nguyen Donny Hartanto Hoai-Nam tran Vinh Thanh tran Van-Khanh Hoang Pham nhu Viet Ha Institute for Nuclear Science and Technology(INST) Vietnam Atomic Energy Institute(VINATOM)179 Hoang Quoc Viet str.Cau Giay DistrictHanoi 100000Vietnam Nuclear Research Institute(NRI) Vietnam Atomic Energy Institute(VINATOM)01 Nguyen Tu LucDalatLamdong 670000Vietnam Department of Mechanical and Nuclear Engineering University of SharjahPO.BOX 27272SharjahUnited Arab Emirates Institute of Fundamental and Applied Sciences Duy Tan UniversityHo Chi Minh city 700000Vietnam Faculty of Natural Science Duy Tan UniversityDanang 550000Vietnam Nuclear Safety Division Technical Support Center for Radiation and Nuclear Safety and Emergency ResponseVietnam Agency for Radiation and Nuclear Safety(VARANS)113 Tran Duy Hung str.Cau Giay DistrictHanoi 100000Vietnam

Cross-sectional homogenization for full-core calculations of small and complex reactor configurations,such as research reactors,has been recently recognized as an interesting and challenging *** paper presents the development of a PARCS/Serpent model for the neutronics analysis of a research reactor type TRIGA Mark-II loaded with Russian VVR-M2 fuel(known as the Dalat Nuclear Research Reactor or DNRR).The full-scale DNRR model and a supercell model for a shim/safety rod and its surrounding fuel bundles with the Monte Carlo code Serpent 2 were proposed to generate homogenized fewgroup cross sections for full-core diffusion calculations with *** full-scale DNRR model with Serpent 2 was also utilized as a reference to verify the PARCS/Serpent *** of the effective neutron multiplication factors,radial and axial core power distributions,and control rod worths showed a generally good agreement between PARCS and Serpent *** addition,the discrepancies between the PARCS and Serpent 2 results are also ***,the results indicate the applicability of the PARCS/Serpent model for further steady state and transient analyses of the DNRR.

关键词： PARCS Serpent 2 Group constant DNRR

transfer Learning for Disease Diagnosis from Myocardial Perfusion SPECT Imaging

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Computers, Materials & Continua 2022年第12期73卷 5925-5941页

作者： Phung nhu Hai Nguyen Chi Thanh Nguyen Thanh Trung tran Trung Kien Institute of Information Technology AMSTHanoi11307Vietnam Department of Medical Equipment 108 Military Central HospitalHanoi11610Vietnam

Coronary artery disease(CAD)is one of the most common pathological conditions and the major global cause of *** perfusion imaging(MPI)using single-photon emission computed tomography(SPECT)is a non-invasive method and plays an essential role in diagnosing ***,there is currently a shortage of doctors who can diagnose using SPECT-MPI in developing countries,especially *** on deploying machine learning and deep learning in supporting CAD diagnosis has been noticed for a long ***,these methods require a large dataset and are therefore time-consuming and *** study aims to develop a cost-effective and high-performance CAD classification model to support doctors in these *** this paper,we propose a transfer learning framework for a multi-stage training process with different learning *** process consists of two training stages:a warming up stage in which all layers of a pre-trained model(on ImageNet dataset)are frozen;and a finetuning stage in which a small amount of the top layers are unfrozen and then retrained with a lower learning *** dataset for this study consists of the polar maps from 218 *** popular CNN-based pre-trained models have been investigated,and ResNet152V2-based model has obtained the highest performances with an accuracy of 95.5%,area under the receiver operating characteristic curve(AUC)score 0.932,sensitivity 94.4%,precision 96.4%,and F1-score 95.2%.These performances are competitive or even better than all state-of-the-art approaches in terms of classification accuracy and *** also apply the class activation mapping technique to help explain the model’s predictions and increase the model’s reliability,proving capable of assisting the SPECT image readers in the CAD diagnosis.

关键词： Coronary artery disease deep learning transfer learning SPECTMPI polar maps

Monte Carlo simulation of a cone-beam CT system for lightweight casts

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Radiation Detection Technology and Methods 2021年第4期5卷 504-512页

作者： Thuy duong tran Ngoc Ha Bui Kim Tuan tran Ngoc Toan tran Department of Nuclear Engineering and Environmental Physics School of Engineering PhysicsHanoi University of Science and Technology01 Dai Co VietHai Ba TrungHanoiVietnam Vietnam Atomic Energy Institute 59 Ly Thuong KietHoan KiemHanoiVietnam

Cone-beam computed tomography(CBCT),a modern technique with many applications,is becoming increasingly important and essential in many areas of economics and *** equipment has been commercialized in both hardware and ***,having a device system suitable for a specific group of objects will be the *** work used Monte Carlo simulation to optimize the design of a Cone-beam Computed Tomography(CBCT)for lightweight and small-size *** affecting image quality such as radiation-source,flat-panel detector,and geometrical distance were *** results indicate that an X-ray generator with a focal spot size of 4×4µm^(2),high voltage of 240 kV,and a radiation intensity of 10^(13) photon/s with a flat panel CsI(Tl)detector of 0.3 mm thickness and a pixel size of 0.1–0.2 mm,is suitable for a CBCT to inspect small objects in *** Monte Carlo model was validated against experiments and to evaluate some characteristics of the existing system.

关键词： Cone-beam computed technology Monte Carlo simulation Lightweight casts in industry Applied radiation

Profiling of Urban Noise Using Artificial Intelligence

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Computer Systems Science & Engineering 2023年第5期45卷 1309-1321页

作者： Le Quang Thao duong Duc Cuong tran Thi Tuong Anh tran Duc Luong Ph.D.Faculty of Physics VNU University of ScienceHanoi100000Vietnam University of Science Vietnam National UniversityHanoi100000Vietnam The International School of Penang(Uplands) PenangMalaysia Alpha School Hanoi100000Vietnam

Noise pollution tends to receive less awareness compared to other types of pollution,however,it greatly impacts the quality of life for humans such as causing sleep disruption,stress or hearing *** urban sound through the identification of noise sources in cities could help to benefit livability by reducing exposure to noise pollution through methods such as noise control,planning of the soundscape environment,or selection of safe living *** this paper,we proposed a self-attention long short-term memory(LSTM)method that can improve sound classification compared to previous *** attention mechanism will be designed solely to capture the key section of an audio data *** is practical as we only need to process important parts of the data and can ignore the rest,making it applicable when gathering information with long-term *** dataset used is the Urbansound8k dataset which specifically pertains to urban environments and data augmentation was applied to overcome imbalanced data and dataset *** audio sources in the dataset were normalized to mono *** the dataset above,an experiment was conducted to confirm the suitability of the proposed model when applied to the mel-spectrogram and MFCC(Mel-Frequency Cepstral Coefficients)datasets transformed from the original *** the classification accuracy depends on the machine learning models as well as the input data,therefore we have evaluated different class models and extraction methods to find the best *** combining data augmentation techniques and various extraction methods,our classification model has achieved state-of-the-art performance,each class accuracy is up to 98%.

关键词： Urban noise noise classification mel-spectrogram MFCC LSTM self-attention