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Digital ID framework for human-centric monitoring and control of smart buildings

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Building Simulation 2022年第10期15卷 1709-1728页

作者： Min Deng Xi Wang Da Li carol C.Menassa Department of Civil and Environmental Engineering University of MichiganAnn ArborMI 48109USA Glenn Department of Civil Engineering Clemson UniversityClemsonSC 29634USA

Smart offices can help employers attract and retain talented people and can positively impact well-being and *** to emerging technologies and increased computational power,smart buildings with a specific focus on personal experience are gaining ***-time monitoring and estimation of the human states are key to achieving individual *** some studies have incorporated real-time data into the buildings to predict occupants’indoor experience(e.g.,thermal comfort and work engagement),a detailed framework to integrate personal prediction models with building systems has not been well ***,this paper proposes a framework to predict and track the real-time states of each individual and assist with decision-making(e.g.,room assignment and indoor environment control).The core idea of the framework is to distinguish individuals by a new concept of Digital ID(DID),which is then integrated with recognition,prediction,recommendation,visualization,and feedback *** establishment of the DID database is discussed and a systematic prediction methodology to determine occupants’indoor comfort is *** on the prediction results,the Comfort Score Index(CSI)is proposed to give recommendations regarding the best-fit rooms for each *** addition,a visualization platform is developed for real-time monitoring of the indoor *** demonstrate the framework,a case study is *** thermal sensation is considered the reference for the room allocation,and two groups of people are used to demonstrate the framework in different *** one group of people,it is assumed that they are existing occupants with personal DID *** in another group are considered the new occupants without any personal database,and the public database is used to give initial guesses about their thermal *** results show that the recommended rooms can provide better thermal environments for the occupan

关键词： smart office digital ID(DID) comfort prediction space recommendation human-centric monitoring real-time visualization

Impact of asialoglycoprotein receptor deficiency on the development of liver injury

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World Journal of Gastroenterology 2009年第10期15卷 1194-1200页

作者： Serene ML Lee carol A Casey Benita L McVicker Departments of Internal Medicine and Biochemistry & Molecular Biology University of Nebraska Medical Center Omaha NE 68105 United States Liver Study Unit Department of Veterans Affairs Medical Center and Departments of Internal Medicine and Biochemistry & Molecular Biology University of Nebraska Medical Center Omaha NE 68105 United States

The asialoglycoprotein （ASGP） receptor is a wellcharacterized hepatic receptor that is recycled via the common cellular process of receptor-mediated endocytosis （RME）. The RME process plays an integral part in the proper trafficking and routing of receptors and ligands in the healthy cell. Thus, the missorting or altered transport of proteins during RME is thought to play a role in several diseases associated with hepatocyte and liver dysfunction. Previously, we examined in detail alterations that occur in hepatocellular RME and associated receptor functions as a result of one particular liver injury, alcoholic liver disease （ALD）. The studies revealed profound ethanol- mediated impairments to the ASGP receptor and the RME process, indicating the importance of this receptor and the maintenance of proper endocytic events in normal tissue. To further clarify these observations, studies were performed utilizing knockout mice （lacking a functional ASGP receptor） to which were administered several liver toxicants. In addition to alcohol, we examined the effects following administration of anti- Fas （CD95） antibody, carbon tetrachloride （CCh） and lipopolysaccharide （LPS）/galactosamine. The results of these studies demonstrated that the knockout mice sustained enhanced liver injury in response to all of the treatments, as shown by increased indices of liver damage, such as enhancement of serum enzyme levels, histopathological scores, as well as hepatocellular death. Overall, the work completed to date suggests a possible link between hepatic receptors and liver injury. In particular, adequate function and content of the ASGP receptor may provide protection against various toxinmediated liver diseases.

关键词： Asialoglycoprotein receptor Asialoglycoproteinreceptor deficient mice Receptor-mediatedendocytosis Alcohol Carbon tetrachloride Anti-Fas Lipopolysaccharide/galactosamine Toxicant-induced liverinjury

Gap analysis on open data interconnectivity for disaster risk research

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Geo-Spatial Information Science 2019年第1期22卷 45-58页

作者： Guoqing Li Jing Zhao Virginia Murray carol Song Lianchong Zhang Key Laboratory of Digital Earth Science Institute of Remote Sensing and Digital EarthChinese Academy of SciencesBeijingChina Hainan Key Laboratory of Earth Observation SanyaChina Institute of Remote Sensing and Digital Earth University of Chinese Academy of SciencesBeijingChina Public Health England Health and Social CareLondonUK Rosen Centre for Advance Computing Purdue UniversityWest LafayetteINUSA

Open data strategies are being adopted in disaster-related data particularly because of the need to provide information on global targets and indicators for implementation of the Sendai Framework for Disaster Risk Reduction 2015–*** all phases of disaster risk management including forecasting,emergency response and post-disaster reconstruction,the need for interconnected multidisciplinary open data for collaborative reporting as well as study and analysis are apparent,in order to determine disaster impact data in timely and reportable *** extraordinary progress in computing and information technology in the past decade,such as broad local and wide-area network connectivity(***),highperformance computing,service and cloud computing,big data methods and mobile devices,provides the technical foundation for connecting open data to support disaster risk research.A new generation of disaster data infrastructure based on interconnected open data is evolving *** are two levels in the conceptual model of Linked Open Data for Global Disaster Risk Research(LODGD)Working Group of the Committee on Data for Science and Technology(CODATA),which is the Committee on Data of the International Council for Science(ICSU):data characterization and data *** data characterization,the knowledge about disaster taxonomy and data dependency on disaster events requires specific scientific study as it aims to understand and present the correlation between specific disaster events and scientific data through the integration of literature analysis and semantic knowledge *** connection concepts deal with technical methods to connect distributed data resources identified by data characterization of disaster *** the science community,interconnected open data for disaster risk impact assessment are beginning to influence how disaster data are shared,and this will need to extend data coverage and provide better ways of utilizing data across domains

关键词： Open data interconnectivity gap analysis disaster risk

Dissociation and disasters: A systematic review

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World Journal of Psychiatry 2019年第6期9卷 83-98页

作者： Fatih Canan carol S North The Altshuler Center for Education&Research at Metrocare Services DallasTX 75390United States Department of Psychiatry The University of Texas Southwestern Medical CenterDallasTX 75390United States

BACKGROUND Dissociation,which is defined as the failure to associate consciousness,memory,identity,emotion,perception,body representation,motor control,and behavior into an integrated whole,has long been assumed to be generated by *** dissociation is a product of trauma exposure,then dissociation would be a major mental health outcome observed in studies of disaster *** some studies have examined dissociation in disasters,no systematic literature reviews have been conducted to date on the *** To systematically evaluate the literature on the association between disaster and dissociation to determine the prevalence and incidence of dissociation after exposure to disaster and further examine their *** EMBASE,Medline,and PsychINFO were searched from inception to January 1,2019 to identify studies examining dissociative disorders or symptoms related to a disaster in adult or child disaster survivors and disaster *** of military conflicts and war,articles not in English,and those with samples of 30 or more participants were *** terms used were“disaster*”and dissociation(“dissociat*,”“multiple personality,”“fugue,”“psychogenic amnesia,”“derealization,”and“depersonalization”).Reference lists of identified articles were scrutinized to identify studies for additional *** The final number of articles in the review was 53,including 36 articles with samples of adults aged 18 and above,5 of children/adolescents under age 18,and 12 of disaster *** articles studied several types of disasters that occurred between 1989 and 2017,more than one-third(38%)from the United *** two studies had a primary aim to investigate dissociation in relation to disaster and none reported data on dissociative *** of the studies used self-report symptom scales;none used structured interviews providing full diagnostic assessment of dissociative disorders or other *** stud

关键词： Dissociation Dissociative disorders Disaster Systematic review Methodology Diagnostic validity Psychopathology Normative response Posttraumatic stress Association vs causation

Capsule endoscopy:the road ahead

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World Journal of Gastroenterology 2016年第1期22卷 369-378页

作者： Ana-Maria Singeap carol Stanciu Anca Trifan Gastroenterology and Hepatology Institute “Gr.T.Popa”University of Medicine and Pharmacy“St.Spiridon”Emergency Hospital700111 IasiRomania Gastroenterology and Hepatology Institute “St.Spiridon”Emergency Hospital700111 IasiRomania

Since its introduction into clinical practice 15 years ago,capsule endoscopy(CE)has become the first-line investigation procedure in some small bowel pathologies,and more recently,dedicated esophageal and colon CE have expanded the fields of application to include the upper and lower gastrointestinal *** this time,CE has become increasingly popular among gastroenterologists,with more than 2 million capsule examinations performed worldwide,and nearly 3000Pub Med-listed studies on its different aspects *** huge interest in CE may be explained by its noninvasive nature,patient comfort,safety,and access to anatomical regions unattainable via conventional ***,CE has several limitations which impede its wider clinical applications,including the lack of therapeutic capabilities,inability to obtain biopsies and control its *** research groups are currently working to overcome these limitations,while novel devices able to control capsule movement,obtain high quality images,insufflate the gut lumen,perform chromoendoscopy,biopsy of suspect lesions,or even deliver targeted drugs directly to specific sites are under *** current limitations,especially as some of them have already been successfully surmounted,and based on the tremendous progress in technology,it is expected that,by the end of next 15years,CE able to perform both diagnostic and therapeutic procedures will remain the major form of digestive *** review summarizes the literature that prognosticates about the future developments of CE.

关键词： Capsule endoscopy Biopsy Drug deliverysystems Capsule endoscope locomotion Capsulelocalization

International Trade Norms in the Age of Covid-19 Nationalism on the Rise?

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Fudan Journal of the Humanities and Social Sciences 2021年第1期14卷 41-66页

作者： Nicolas Albertoni carol Wise Department of Political Science&International Relations University of Southern CaliforniaLos AngelesUSA

Simultaneous with the rise of trade protectionism in the twenty-first century has been a resurgence in nationalist politics,most notably in the USA,the UK,and parts of the *** developments in international and US trade policy,including Washington’s launch of a full-fledged trade war against China in March 2018,have converged disastrously with the outbreak of the novel coronavirus in November 2019 and the onset of a worldwide *** the status of the USA as the world’s hegemon since 1945,what is new here is the effort of the Trump administration to abdicate US leadership,-jettison longstanding alliances,and turn back the clock on the country’s close integration with the world ***,greatly reduced flows of goods,services,and people have translated into radically reduced global growth,widespread business disruptions,and high ***,the White House has refused to recognize the severity of the pandemic and has undermined the precautions of the US science *** argue that these multiple shocks constitute a major critical juncture on par with what the world community faced in ***,in the twenty-first century we have seen that high levels of economic uncertainty and political instability have superseded the long-held notion that international interdependence would pull the world community through tough times such as *** the triple whammy of a destructive trade war,deadly pandemic,and secular decfine of US leadership trigger a new generation of policy innovation and institution building on par with the post-1945 era?In terms of the global trade regime,it would be difficult to imagine a buoyant recovery of the world economy in the absence of a serious reckoning with the pattern of norm erosion that we identify here.

关键词： China USA World Trade Organization Non-tariff barriers Novel corona virus Nationalism Globalization

Lymphocytic esophagitis: Still an enigma a decade later

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World Journal of Gastroenterology 2017年第6期23卷 949-956页

作者： carol Rouphael Ilyssa O Gordon Prashanthi N Thota Department of General Internal Medicine Cleveland Clinic Foundation Department of Pathology Cleveland Clinic Foundation Department of Gastroenterology and Hepatology Digestive Disease and Surgery InstituteCleveland Clinic Foundation

Lymphocytic esophagitis (LE) is a clinicopathologic entity first described by Rubio et al in 2006. It is defined as peripapillary intraepithelial lymphocytosis with spongiosis and few or no granulocytes on esophageal biopsy. This definition is not widely accepted and the number of lymphocytes needed to make the diagnosis varied in different studies. Multiple studies have described potential clinical associations and risk factors for LE, such as old age, female gender and smoking history. This entity was reported in inflammatory bowel disease in the pediatric population but not in adults. Other associations include gastroesophageal reflux disease and primary esophageal motility disorders. The most common symptom is dysphagia, with a normal appearing esophagus on endoscopy, though esophageal rings, webs, nodularities, furrows and strictures have been described. Multiple treatment modalities have been used such as proton pump inhibitors and topical steroids. Esophageal dilation seems to be therapeutic when dysphagia is present along with esophageal narrowing secondary to webs, rings or strictures. The natural history of the disease remains unclear and needs to be better delineated. Overall, lymphocytic esophagitis seems to have a chronic and benign course, except for two cases of esophageal perforation in the literature, thought to be secondary to this entity.

关键词： Lymphocytic esophagitis intraepithelial lymphocytes spongiosis gastroesophageal reflux disease CD4 T-cells dysphagia inflammatory bowel disease esophageal rings proton pump inhibitors esophageal dilation

Gesture recognition for transhumeral prosthesis control using EMG and NIR

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IET Cyber-Systems and Robotics 2020年第3期2卷 122-131页

作者： Ejay Nsugbe carol Phillips Mike Fraser Jess McIntosh University of Bristol Queen's BuildingUniversity WalkBristol BS81TRUK Department of Radiology University Hospitals BristolNHS Foundation TrustBristolUK

A key challenge associated with myoelectric prosthesis limbs is the acquisition of a good quality gesture intent signal from the residual anatomy of an *** this study,the authors aim to overcome this limitation by observing the classification accuracy of the fusion of wearable electromyography(EMG)and near-infrared(NIR)to classify eight hand gesture motions across 12 able-bodied *** part of the study,they investigate the classification accuracy across a multi-layer perceptron neural network,linear discriminant analysis and quadratic discriminant analysis for different sensing configurations,***-only,NIR-only and EMG-NIR.A separate offline ultrasound scan was conducted as part of the study and served as a ground truth and contrastive basis for the results picked up from the wearable sensors,and allowed for a closer study of the anatomy along the humerus during gesture *** and findings from the work suggest that it could be possible to further develop transhumeral prosthesis using affordable,ergonomic and wearable EMG and NIR sensing,without the need for invasive neuromuscular sensors or further hardware complexity.

关键词： anatomy prosthesis EMG

Relationship of functional gastrointestinal disorders and psychiatric disorders: Implications for treatment

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World Journal of Gastroenterology 2007年第14期13卷 2020-2027页

作者： carol S North Barry A Hong David H Alpers Department of Psychiatry The University of Texas Southwestern Medical Center at Dallas and North Texas VA Health Care System DallasTXUnited States Department of Psychiatry Washington University School of Medicine St. LouisMOUnited States Department of Internal Medicine Division of Gastroenterology Washington University School of MedicineSt. LouisMOUnited States

This article revisits the links between psychopathology and functional gastrointestinal disorders such as irritable bowel syndrome （IBS）, discusses the rational use of antidepressants as well as non-pharmacological approaches to the management of IBS, and suggests guidelines for the treatment of IBS based on an interdisciplinary perspective from the present state of knowledge. Relevant published literature on psychiatric disorders, especially somatization disorder, in the context of [BS, and literature providing direction for management is reviewed, and new directions are provided from findings in the literature. IBS is a heterogeneous syndrome with various potential mechanisms responsible for its clinical presentations. IBS is typically complicated with psychiatric issues, unexplained symptoms, and functional syndromes in other organ systems. Most IBS patients have multiple complaints without demonstrated cause, and that these symptoms can involve systems other than the intestine, e.g. bones and joints （fibromyalgia, temporomandibular joint syndrome）, heart （non-cardiac chest pain）, vascular （post-menopausal syndrome）, and brain （anxiety, depression）. Host IBS patients do not have psychiatric illness per se, but a range of psychoform （psychological complaints in the absence of psychiatric disorder） symptoms that accompany their somatoform （physical symptoms in the absence of medical disorder） complaints. It is not correct to label IBS patients as psychiatric patients （except those more difficult patients with true somatization disorder）. One mode of treatment is unlikely to be universally effective or to resolve most symptoms. The techniques of psychotherapy or cognitive-behavioral therapy can allow IBS patients to cope more readily with their illness. Specific episodes of depressive or anxiety disorders can be managed as appropriate for those conditions. Medications designed to improve anxiety or depression are not uniformly useful for psychiatric complaints in IB

关键词： Irritiable bowel syndrome Functionadisorders Gastrointestinal disease Somatization disorderSomatoform Psychoform Psychotropic medicationPsychotherapy Symptoms Psychiatric disorder