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Current and future of anterior cruciate ligament reconstruction techniques

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World Journal of Meta-Analysis 2021年第5期9卷 411-437页

作者： Toshiaki Takahashi Seiji Watanabe toshio ito Department of Sports and Health Science Ehime UniversityMatsuyama 790-8577EhimeJapan Department of Orthopedic Surgery Ehime University Graduate School of MedicineToon 791-0295EhimeJapan Department of Orthopaedic Surgery Murakami Memorial HospitalSaijo 793-0030EhimeJapan

In recent years,anterior cruciate ligament(ACL)reconstruction has generally yielded favorable ***,ACL reconstruction has not provided satisfactory results in terms of the rate of returning to sports and prevention of osteoarthritis(OA)*** this paper,we outline current techniques for ACL reconstruction such as graft materials,double-bundle or single-bundle reconstruction,femoral tunnel drilling,all-inside technique,graft fixation,preservation of remnant,anterolateral ligament reconstruction,ACL repair,revision surgery,treatment for ACL injury with OA and problems,and discuss expected future *** enable many more orthopedic surgeons to achieve excellent ACL reconstruction outcomes with less invasive surgery,further studies aimed at improving surgical techniques are *** development of biological augmentation and robotic surgery technologies for ACL reconstruction is also required.

关键词： Anterior cruciate ligament reconstruction Surgical techniques Revision surgery Biological augmentation Computer-aided surgery

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桑蟥和野蚕的茧层氨基酸组成

国外农学（蚕业） 1993年第1期 30-32页

作者： toshio ito 吴小锋

桑蟥(Rondotia menciana)属蚕蛾科,是中国的一种桑树害虫。它虽能吐丝结茧,但茧子很小,通常依附在桑叶表面上。野蚕(Bombyx mandarina)在亚洲的许多地区均有发生,广泛分布于日本,中国大陆、朝鲜半岛、中国台湾等。

关键词：桑蟥野蚕蚕茧氨基酸

Synchrotron Refraction Enhanced Tomography of an Intact Common Marmoset (<i>Callithrix jacchus</i>)

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Open Journal of Radiology 2011年第2期1卷 28-37页

作者： Toshihiro Sera Hideo Yokota SakikoS. Nakamura Kentaro Uesugi Masato Hoshino Naoto Yagi toshio ito Keigo Hikishima Hirotaka James Okano 不详

The common marmoset (Callithrix jacchus), a small new world monkey species, has been widely used in various scientific fields. It is necessary to understand connections between specific genotypes, their structure, and function;however, an anatomical atlas of the entire body of the common marmoset has not yet been reported. In addition to conventional absorption, refraction enhanced computed tomography (CT) based on synchrotron radiation can increase the contrast of boundaries between small absorption differences. In this study, to examine the potential of creating an anatomical atlas of the whole body of the common marmoset non-invasively, we visualized an intact marmoset using synchrotron refraction enhanced CT. The cryogenic marmoset was scanned using the medical imaging beamline at the SPring-8 synchrotron radiation research facility in JAPAN. The trabecular structure, articular cartilage, cruciate ligament in the knee joint, and small airways (diameter: > 400 μm) was clearly identified with 50 μm voxel size and 37 keV x-ray energy. The structure of the heart and branching vessels in the kidneys and liver were also identified without contrast agents, and the anatomical structure of the brain was slightly visible. These results show that synchrotron refraction enhanced CT is useful for creating an anatomical atlas non-invasively, and further studies are planned that will combine refraction enhanced CT and other imaging techniques to analyse the morphology and create a complete atlas of the whole body of the common marmoset.

关键词： Common Marmoset CT Refraction Enhancement Synchrotron

A Blowdown Cryogenic Cavitation Tunnel and CFD Treatment for Flow Visualization around a Foil

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Journal of Thermal Science 2005年第4期14卷 346-351页

作者： Yutaka ito Kazuya SAWASAKI Naoki TANI Takao NAGASAKI toshio NAGASHIMA Tokyo Institute of Technology G3-334259Nagatsuta-choMidori-kuYokohama226-8502Japan Honda Motor Co.Ltd. 2-1-1Minami-AoyamaMinato-kuTokyo107-8556Japan Japan Aerospace Exploration Agency 2-1-1SengenTsukuba305-8505Japan University of Tokyo 7-3-1HongoBunkyo-kuTokyo113-8656Japan

Cavitation is one of the major problems in the development of rocket engines. There have been few experimental studies to visualize cryogenic foil cavitation. Therefore a new cryogenic cavitation tunnel of blowdown type was built. The foil shape is “piano-convex”. This profile was chosen because of simplicity, but also of being similar to the one for a rocket inducer impeller. Working fluids were water at room temperature, hot water and liquid nitrogen. In case of Angle of Attack （AOA）=8°, periodical cavity departure was observed in the experiments of both water at 90℃ and nitrogen at -190℃ under the same velocity 10 m/sec and the same cavitation number 0.7. The frequencies were observed to be 110 and 90 Hz, respectively, and almost coincided with those of vortex shedding from the foil. Temperature depression due to the thermodynamic effect was confirmed in both experiment and simulation especially in the cryogenic cavitation.

关键词： cavitation tunnel cryogen CFD visualization simulation foil.

Miscibility,Intramolecular Specific Interactions and Mechanical Properties of a DGEBA Based Epoxy Resin Toughened with a Sliding Graft Copolymer

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Chinese Journal of Polymer Science 2015年第3期33卷 433-443页

作者： Xue Li Hai-lan Kang Jian-xiang Shen 张立群 toshio Nishi Kohzo ito State Key Laboratory for Organic-Inorganic Composites Beijing University of Chemical Technology Key Laboratory of Beijing City for Preparation and Processing of Novel Polymer Materials Beijing University of Chemical Technology Department of Applied Physics The University of Tokyo Department of Advanced Materials Science Graduate School of Frontier SciencesThe University of Tokyo

The ＂sliding graft copolymer＂（SGC）, in which many linear poly-ε-caprolactone （PCL） side chains are bound to cyclodextrin rings of a polyrotaxane （PR）, was prepared and employed to toughen diglycidyl ether of bisphenol A （DGEBA） based epoxy resin. The aim of the work is to understand the effect of SGC on the miscibility, morphology, thermal behavior, curing reaction and mechanical performance of the cured systems. From differential scanning calorimetry （DSC） analysis and dynamic mechanical thermal analysis （DMTA） of DGEBA/SGC thermosetting blends, it is found that DGEBA and SGC are miscible in the amorphous state. Fourier transform infrared spectroscopy （FTIR） suggested that the miscibility between SGC and DGEBA is due to the existence of intermolecular specific interactions （viz. hydrogen bonding）. The impact strength is improved by 4 times for DGEBA/SGC （80/20） blends compared with that of the unmodified system. The increase in toughness of SGC-modified thermosets can be explained by the effect of intermolecular specific interactions of SGC with DGEBA, which is beneficial to induce the plastic deformation of matrix. This is the first report on utilizing this novel supramolecular polymer to toughen rigid epoxy matrix.

关键词： Epoxy Sliding graft copolymer Toughen Miscibility Hydrogen bonding.

Synchronous pancreatic solid pseudopapillary neoplasm and intraductal papillary mucinous neoplasm

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World Journal of Gastroenterology 2013年第21期19卷 3358-3363页

作者： Kenichi Hirabayashi Giuseppe Zamboni Hiroyuki ito Masami Ogawa Yoshiaki Kawaguchi Tomohiro Yamashita toshio Nakagohri Naoya Nakamura Department of Pathology Tokai University School of MedicineIsehara 259-1193Japan Department of Pathology Ospedale Sacro Cuore Don Calabria37024 Negrar VeronaItaly Department of Pathology University of Verona37134 Negrar VeronaItaly Department of Gastroenterology Tokai University School of MedicineIsehara 259-1193Japan Department of Radiology Tokai University School of MedicineIsehara 259-1193Japan Department of Gastroenterological Surgery Tokai University School of MedicineIsehara 259-1193Japan

Solid pseudopapillary neoplasm (SPN) is a rare and low-grade malignant pancreatic neoplasm composed of poorly cohesive monomorphic neoplastic cells forming solid and pseudopapillary structures with frequent hemorrhagic-cystic degeneration. Intraductal papillary mucinous neoplasm (IPMN) is a pancreatic exocrine tumor composed of intraductal papillary growth of mucin containing neoplastic cells in the main pancreatic duct or its major branches. In the case presented here, a 53-year-old, Japanese man was found to have multiple cystic lesions and dilatation of the main pancreatic duct in the neck of the pancreas. Histological examination revealed a main-duct and branch-duct type IPMN, of the gastric-type, involving the neck of the pancreas, associated with a 0.5 cm SPN in the caudal side of the IPMN. We diagnosed this case as synchronous SPN and IPMN. As far as we know, only one other case of synchronous SPN and IPMN has been reported. Both the present case and the previously reported case showed abnormal nuclear expression of β-catenin in SPN, whereas IPMN showed no abnormal nuclear expression. These results suggest that β-catenin abnormality is not a common pathogenetic factor of synchronous SPN and IPMN.

关键词： Intraductal papillary mucinous neoplasms Solid pseudopapillary neoplasms Pancreatic neoplasms Synchronous neoplasms Pancreas Beta-catenin

Clinical efficacy of a combination of Percoll continuous density gradient and swim-up techniques for semen processing in HIV-1 serodiscordant couples

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Asian Journal of Andrology 2017年第2期19卷 208-213页

作者： Osamu Inoue Naoaki Kuji Hiroe ito Mitsutoshi Yamada toshio Hamatani Aimi Oyadomari Shingo Kato Hideji Hanabusa Keiichi Isaka Mamoru Tanaka Department of Obstetrics and Gynecology Keio University School of Medicine Tokyo 1608582 Japan Department of Obstetrics and Gynecology Tokyo Medical College Tokyo 1600023 Japan Department of Microbiology Keio University School of Medicine Tokyo 1608582 Japan Department of Hematology Ogikubo Hospital Tokyo 1670035 Japan

To evaluate the clinical efficacy of a procedure comprising a combination of Percoll continuous density gradient and modified swim-up techniques for the removal of human immunodeficiency virus type 1 （HIV-1） from the semen of HIV-1 infected males, a total of 129 couples with an HIV-1 positive male partner and an HIV-1 negative female partner （serodiscordant couples） who were treated at Keio University Hospital between January 2002 and April 2012 were examined. A total of 183 ejaculates from 129 HIV-1 infected males were processed. After swim-up, we successfully collected motile sperms at a recovery rate as high as 100.0% in cases of normozoospermia （126/126 ejaculates）, oligozoospermia （6/6）, and asthenozoospermia （36/36）. The recovery rate of oligoasthenozoospermia was 86.7% （13/15）. In processed semen only four ejaculates （4/181：2.2%） showed viral nucleotide sequences consistent with those in the blood of the infected males. After using these sperms, no horizontal infections of the female patients and no vertical infections of the newborns were observed. Furthermore, no obvious adverse effects were observed in the offspring. This protocol allowed us to collect HIV-1 negative motile sperms at a high rate, even in male factor cases. We concluded that our protocol is clinically effective both for decreasing HIV-1 infections and for yielding a healthy child.

关键词： assisted reproductive technology human immunodeficiency virus type 1 serodiscordant couPle viral nucleotide sequence

Beneficiaries’ Willingness to Pay for Resuscitation Provided by Ambulance Attendants: A Survey Using the Contingent Valuation Approach

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Health 2017年第10期9卷 1367-1377页

作者： Yukie ito Manabu Akahane Akie Maeyashiki toshio Ogawa Tomoaki Imamura Department of Public Health Health Management and Policy Nara Medical University Nara Japan Department of Health and Welfare and Health Service Management International University of Health and Welfare Tokyo Japan

Background: Japanese emergency medical services (EMS) can be used by anyone for free. Recently, EMS usage has increased;the increased costs and the prolonged time for ambulance transport have become recent social problems. Objective: We surveyed the willingness to pay (WTP) for resuscitation provided by EMS. Methods: In November 2011, men and women (3160) aged 20 - 59 years were asked to assume that they were experiencing a cardiopulmonary arrest (CPA), and their WTP for EMS services was assessed in the following three situations: Case A, ambulance transport alone;Case B, chest compression in addition to ambulance transport;and Case C, artificial ventilation through chest compression and intratracheal intubation, in addition to ambulance transport. We calculated the mean WTP for each case. Results: The WTP for Case A, B, and C were ￥6,696 ($65.0), ￥16,081 ($156.1), and ￥27,505 ($267.0), respectively. The WTP for Case B was significantly higher in respondents aged 40 - 59 years compared to those aged 20 - 39 years. The WTP for case B and C were significantly higher in males compared to females. WTP was significantly lower in students than it was in private employees. Although women’s intention to pay was higher than that of men, their WTP was lower than that of men. Public employees’ and students’ intention to pay was significantly lower than that of private employees. Conclusions: Our study provides information about the optimal fee for EMS, which will be useful for discussions on the feasibility of introducing a fee for EMS in Japan.

关键词： Emergency Medical Services Willingness to Pay Chest Compression Tracheal Intubation Resuscitation

Small serotonin-positive pancreatic endocrine tumors caused obstruction of the main pancreatic duct

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World Journal of Gastroenterology 2012年第45期18卷 6669-6673页

作者： Masami Ogawa Yoshiaki Kawaguchi Atsuko Maruno Hiroyuki ito toshio Nakagohri Kenichi Hirabayashi Hiroshi Yamamuro Tomohiro Yamashita Tetsuya Mine Department of Gastroenterology Tokai University School of Medicine143 ShimokasuyaIsehara 259-1193Japan Department of Gastroenterological Surgery Tokai University School of Medicine143 ShimokasuyaIsehara 259-1193Japan Department of Pathology Tokai University School of Medicine143 ShimokasuyaIsehara 259-1193Japan Department of Radiology Tokai University School of Medicine143 ShimokasuyaIsehara 259-1193Japan

We report 2 cases of pancreatic endocrine tumors that caused obstruction of the main pancreatic duct(MPD).A 49-year-old asymptomatic man was referred to our institution because dilation of the MPD was revealed by abdominal ultrasonography(US).No tumor was detected by endoscopic ultrasonography,computed tomography(CT),and magnetic resonance imaging(MRI).The diameter of the MPD was > 20 mm at the body,and no dilation was noted at the *** malignancy was not confirmed through cytology or imaging,pancreatic cancer was strongly ***-denectomy was *** and immunohistochemical examination revealed a 5 mm × 3 mm serotonin-positive endocrine *** was present around the MPD and seemed to cause stricture.A 32-year-old asymptomatic man had elevated serum amylase,and US demonstrated dilation of the *** tumor was detected by CT and *** cancer was suspected due to stricture and dilation of the *** of middle part of pancreas was *** and immunohistochemical examination revealed a serotonin-positive endocrine tumor sized 5 mm × 4 *** report 2 cases of serotonin-positive pancreatic endocrine tumors that caused stricture of the MPD in spite of the small size of the tumor.

关键词： Serotonin Pancreatic endocrine tumor Main pancreatic duct Obstruction Dilatation